Abstract:
:Metastases to the gingival soft tissues are rare in hepatocellular carcinoma (HCC). To the best of our knowledge, only 13 cases have been reported in English literature to date. The present study described the case of a 43-year-old Chinese man who was admitted to Tangdu Hospital (Xi'an, China) due to the presence of a gingival tumor that was initially diagnosed as granulation tissue by a dental surgeon. Examination of the patient's medical history revealed that a solid mass, measuring 1.5 cm in diameter, was identified in the right lobe of the liver 2 years prior to presentation at the current hospital; however, no biopsy was performed. Thus, the tumor was resected and histological examination resulted in an initial diagnosis of atypical squamous cell carcinoma. However, the histopathological characteristics, immunohistochemical features and serum α-fetoprotein expression levels supported a diagnosis of metastatic HCC. In conclusion, the present case study highlights the difficulties in diagnosing metastatic HCC without a history of primary HCC, and the importance of excluding a diagnosis of metastatic tumor when a lesion is identified in the gingival. Furthermore, it was determined that a final diagnosis of gingival metastasis of HCC predominantly depends on pathological characteristics and immunohistochemical features.
journal_name
Oncol Lettjournal_title
Oncology lettersauthors
Gong LI,Zhang WD,Mu XR,Han XJ,Yao LI,Zhu SJ,Zhang FQ,Li YH,Zhang Wdoi
10.3892/ol.2015.3422subject
Has Abstractpub_date
2015-09-01 00:00:00pages
1565-1568issue
3eissn
1792-1074issn
1792-1082pii
OL-0-0-3422journal_volume
10pub_type
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