Abstract:
:This research investigated the substances employed by and experiences of patients who come to acute treatment after self-poisoning. A retrospective search of the Toxicology Investigators Consortium Registry was performed to characterize a large cohort of patients. A detailed prospective study of one inpatient toxicology service was also conducted. Patients chose readily available agents for self-poisoning. Most cases involved at least one substance that affects the central nervous system (CNS). The majority were prescription psychotropics and narcotics. When they had access to both CNS-active and CNS-inactive medications, patients almost invariably ingested a mind-altering agent. After recovering neurocognitive function, most patients were not actively experiencing suicidal thoughts. However, more than half of patients without CNS toxicity continued to have suicidal ideation after coming to care. These findings are consistent with the hypothesis that many suicidal patients may be seeking an altered psychosomatic state rather than death per se.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Rasimas JJ,Smolcic EE,Sinclair CMdoi
10.1016/j.psychres.2017.05.049subject
Has Abstractpub_date
2017-09-01 00:00:00pages
304-313eissn
0165-1781issn
1872-7123pii
S0165-1781(16)31323-3journal_volume
255pub_type
杂志文章abstract::Appropriately estimating stress levels in daily life is important for motivating people to undertake stress-management behaviors or seek out information on stress management and mental health. People who exhibit high stress underestimation might not be interested in information on mental health, and would therefore ha...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.12.090
更新日期:2018-04-01 00:00:00
abstract::There are no articles in the international psychiatric literature reporting subclinical visual system disorders in depressed patients, although a disturbance of circadian rhythms is one of the prominent theories of the etiopathogenesis of depression. Fifty patients aged 21-60 years suffering from major depression acco...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(03)00097-0
更新日期:2003-06-15 00:00:00
abstract::Seventeen psychiatric patients (11 with schizophrenia, 5 with other psychotic disorders, and 1 with obsessive-compulsive disorder) were examined by single photon emission computed tomography with 123I-iodobenzamide (IBZM) as tracer. Patients were treated with risperidone in two different dosage groups (3 mg and 8 mg) ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0925-4927(96)02839-9
更新日期:1996-11-25 00:00:00
abstract::Post-traumatic Stress Disorder (PTSD) and Major Depressive Disorder (MDD) are the most common psychiatric consequences among caregivers of pediatric patients affected by severe chronic illnesses. The aims of this study were to describe rates of PTSD and MDD in a sample of parents of epileptic children, and to examine ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.02.062
更新日期:2019-09-01 00:00:00
abstract::This study aimed to determine predictors of BMI and recovery for outpatients with anorexia nervosa (AN). Patients were participants of the ANTOP (Anorexia Nervosa Treatment of Out-Patients) trial and randomized to focal psychodynamic therapy (FPT), enhanced cognitive behavior therapy (CBT-E), or optimized treatment as...
journal_title:Psychiatry research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.psychres.2016.07.002
更新日期:2016-10-30 00:00:00
abstract::Blood dyscrasias excluding agranulocytosis received limited attention in antipsychotic-treated patients during the first 18 weeks of therapy, although severe clinical conditions have been reported in a few cases. We extracted data records of 285 Caucasian patients after 18 weeks of antipsychotic treatments to investig...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.06.068
更新日期:2017-10-01 00:00:00
abstract::Cognitive impairment is a frequent complication of advanced human immunodeficiency virus-1 (HIV-1) infection. However, structural imaging of the brain has not revealed abnormalities that precede the onset of clinical abnormalities. Cranial magnetic resonance (MR) studies were performed in 28 male subjects with intrave...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(93)90047-k
更新日期:1993-05-01 00:00:00
abstract::The inability to modulate processing time in conjunction with varying difficulty levels may be a core component of schizophrenia's cognitive deficit. In this study we used a parametric design to demonstrate this group's inability to increase and decrease response times in association with varying levels of task demand...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2004.04.003
更新日期:2004-07-15 00:00:00
abstract::The cognitive significance of P300 abnormalities in schizophrenia and obsessive-compulsive disorder (OCD) was investigated. P300 was measured by an auditory oddball paradigm, in which a series of standard tones (1000 Hz) and target tones (1500 Hz) were presented. The subject's task was to count the number of the prese...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0925-4927(03)00045-3
更新日期:2003-06-30 00:00:00
abstract::Five women with primary major bipolar affective disorders had variable and at times very high urinary phenylethylamine (PEA) excretion rates. The clinical picture of these patients was characterized by periodic bizarre behaviors and short psychotic episodes. These patients were generally nonresponsive to the usual tre...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(82)90009-9
更新日期:1982-04-01 00:00:00
abstract::High motivation and belief in a cause have been reported to be protective against posttraumatic stress disorder (PTSD), while below-average intellectual functioning and poor educational achievements have been reported to increase vulnerability to PTSD. The main goal of this study was to assess the effect of education,...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(01)00365-1
更新日期:2002-01-31 00:00:00
abstract::Schizophrenia is considered a connectivity disorder. Further, the functional connectivity (FC) of the default-mode network (DMN) has gained the interest of researchers. However, few studies have been conducted on the abnormal connectivity of DMN in early-onset schizophrenia (EOS). In this study, the key brain regions ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.113578
更新日期:2021-01-01 00:00:00
abstract::General practitioners (GP), on the frontline for individuals with mental health problems, often deal with work-related common psychiatric disorders. We aimed to determine the prevalence of work-related common psychiatric disorders in general practice and associated patients' and GPs' characteristics. HERACLES, a cross...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.09.008
更新日期:2018-01-01 00:00:00
abstract::Internalized stigma reduces chances of clinical and subjective recovery in people with schizophrenia and other severe mental illness. To date, there is not enough evidence about an effective intervention to reduce internalized stigma that promotes clinical and subjective recovery in people with high internalized stigm...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.113635
更新日期:2021-01-01 00:00:00
abstract::Ninety-one patients treated with amitriptyline and 60 normal control subjects underwent a standardized heart rate analysis in supine posture. Tests included the determination of time- and frequency-derived measurements of heart rate variability. The patients differed significantly from the control subjects in all para...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(95)02511-t
更新日期:1995-04-28 00:00:00
abstract::There is little information on gender differences in general mental health, smoking, drinking and chronic diseases in Chinese elderly. We examined the gender differences in general mental health, smoking, drinking and a number of chronic diseases in a large Chinese old population. Multistage stratified cluster samplin...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.02.007
更新日期:2017-05-01 00:00:00
abstract::The present follow-up study examines the associations between cognition and parent-rated internalizing problems among adolescents with early-onset schizophrenia (EOS) at baseline (T1) and self-rated internalizing problems 13 years later (T2). Twelve individuals (8 male/4 female) with EOS and 30 healthy controls (16 ma...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.04.033
更新日期:2018-07-01 00:00:00
abstract::Our study aimed to evaluate the presence of antibodies related to gluten intolerance in patients with mood disorders. A total of 60 patients with a diagnosis of bipolar disorder or depressive disorder were recruited. Fourty-eight subjects randomly selected among unrelated family members were included as controls. Celi...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.12.008
更新日期:2018-02-01 00:00:00
abstract::Ninety-five patients hospitalized for acute psychosis were reviewed with respect to hallucinogen use and family history of mental illness. Sixty-three percent of admissions had used hallucinogens to some degree within 3 years of the index admission. Drug users were predominantly male, although no age or diagnostic dif...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(83)90030-6
更新日期:1983-06-01 00:00:00
abstract::Posttraumatic stress disorder (PTSD) and social anxiety disorder (SAD) are highly comorbid (Collimore et al., 2010). Trauma may present a shared environmental factor contributing to the development of comorbidity; however, existent research has been hampered by use of restrictive samples and limitations in the range o...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.10.036
更新日期:2016-12-30 00:00:00
abstract::In the present study we set out to explore the long-term clinical course of schizophrenia in a holistic manner by adopting sequence analysis. Our aim was to identify course types of illness by means of cluster analysis. The study was based on course and outcome data for 107 patients followed up over 134 months after f...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.04.056
更新日期:2015-08-30 00:00:00
abstract::As part of anational Finnish study on reproductive health of women with severe mental disorders, we compared pregnancy- and delivery-, and postpartum-related outcomes between women with schizophrenia (n = 3444) and those with schizoaffective disorder (n = 985), focusing on their singleton pregnancies after illness ons...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.113504
更新日期:2020-12-01 00:00:00
abstract::Posttraumatic stress disorder (PTSD) affects many returning combat veterans, but underlying biological mechanisms remain unclear. In order to compare circulating micro RNA (miRNA) of combat veterans with and without PTSD, peripheral blood from 24 subjects was collected following deployment, and isolated miRNA was sequ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.01.081
更新日期:2017-05-01 00:00:00
abstract::It has been reported that the balance between T-helper type 1 (Th1) cytokines and T-helper type 2 (Th2) cytokines plays a role in psychiatric disorders such as bipolar disorder. The T-helper type 3 (Th3) cytokine, which transforming growth factor beta-1 (TGF-beta1), has been shown to modulate the production of Th1 and...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2004.08.005
更新日期:2004-12-30 00:00:00
abstract::Executive dysfunctions have been consistently demonstrated in patients with schizophrenia. This study aimed to investigate deficits in specific executive functioning components, namely working memory and inhibition, in schizophrenia. In study 1, a set of neurocognitive function tests was administered to 41 patients wi...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2009.07.014
更新日期:2010-10-30 00:00:00
abstract::The pharmacokinetic properties of platelets make these vascular elements a potential and convenient model for serotoninergic neurons. Because we encountered several difficulties in preliminary platelet serotonin (5HT) uptake assays, we explored the influence of several assay factors on the parameters obtained. We foun...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(87)90051-5
更新日期:1987-09-01 00:00:00
abstract::This 1-year longitudinal study of adults who have recently transitioned from homelessness to Permanent Supportive Housing (PSH) focuses on quality of life as a primary outcome of interest. Eighty of 103 new tenants participated in structured interviews at the time of entry into their new home and at 12-months post-hou...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.07.072
更新日期:2014-12-15 00:00:00
abstract::Tourette syndrome (TS) is a heritable disorder characterized by tics that are decreased in some patients by treatment with alpha adrenergic agonists and dopamine receptor blockers. Thus, this study examines the relationship between catecholamine gene expression in blood and tic severity. TS diagnosis was confirmed usi...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2012.04.034
更新日期:2012-12-30 00:00:00
abstract::Social functioning is an important component of mental disorders for assessment and treatment. There is no recognised self-report instrument to measure social functioning across disorders where social impairment is significant. The Social Functioning Scale (SFS) has, however, been used to assess social functioning in ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.03.037
更新日期:2019-06-01 00:00:00
abstract::Preliminary data are presented on levels of plasma cortisol, dopamine (DA), epinephrine (EPI), and norepinephrine (NE) before and after dexamethasone in 22 depressed patients (of whom 4 were psychotic). Platelet monoamine oxidase (MAO) activity, determined in 19 of the depressed patients, was significantly higher in t...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(87)90007-2
更新日期:1987-02-01 00:00:00