Abstract：
:Seventeen psychiatric patients (11 with schizophrenia, 5 with other psychotic disorders, and 1 with obsessive-compulsive disorder) were examined by single photon emission computed tomography with 123I-iodobenzamide (IBZM) as tracer. Patients were treated with risperidone in two different dosage groups (3 mg and 8 mg) and haloperidol (10-20 mg) and compared with eight healthy control subjects. There was a statistically significant difference in basal ganglia/frontal cortex ratios of IBZM binding between controls and all treatment groups. A statistically significant difference was also found concerning these ratios and percentage of dopamine D2 receptor occupancy rates between the treatment groups with lowest ratios and highest percentage of D2 receptor occupancy in the group of patients treated with haloperidol, followed by the group treated with 8 mg of risperidone and the group treated with 3 mg of risperidone.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Küfferle B,Brücke T,Topitz-Schratzberger A,Tauscher J,Gössler R,Vesely C,Asenbaum S,Podreka I,Kasper Sdoi
10.1016/s0925-4927(96)02839-9subject
Has Abstractpub_date
1996-11-25 00:00:00pages
23-30issue
1eissn
0165-1781issn
1872-7123journal_volume
68pub_type
杂志文章abstract：:This study aimed to evaluate the effectiveness of electroconvulsive therapy (ECT) among patients with treatment resistant schizophrenia (TRS). Records of patients who had received ECT were reviewed to identify patients with TRS who were administered ECT in combination with clozapine. Socio-demographic, clinical data a...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.01.042
更新日期：2017-03-01 00:00:00
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journal_title：Psychiatry research
pub_type： 临床试验,杂志文章
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更新日期：2003-08-30 00:00:00
abstract：:Cannabis use has been associated with a continuum of psychotic experiences. However, it is unclear whether mood and anxiety symptoms account for increases in attenuated positive psychotic symptoms (APPS) among cannabis users. We predicted that depression and anxiety symptoms would mediate the relation between cannabis...
journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：2014-08-15 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
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journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：2018-01-01 00:00:00
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journal_title：Psychiatry research
pub_type： 信件
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更新日期：2020-08-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章,评审
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更新日期：2020-01-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.03.010
更新日期：2016-05-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(96)02929-0
更新日期：1996-11-15 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0925-4927(95)02732-d
更新日期：1995-08-08 00:00:00
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pub_type： 杂志文章
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更新日期：2010-06-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.09.053
更新日期：2018-12-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2013.07.034
更新日期：2013-12-30 00:00:00
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pub_type： 杂志文章,meta分析
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更新日期：2018-11-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.04.025
更新日期：2018-06-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.psychres.2020.112797
更新日期：2020-02-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.psychres.2011.05.039
更新日期：2011-10-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2013.11.012
更新日期：2014-02-28 00:00:00
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doi：10.1016/0925-4927(90)90008-t
更新日期：1990-04-01 00:00:00
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pub_type： 杂志文章
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更新日期：2011-10-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(03)00148-3
更新日期：2003-08-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2015.09.008
更新日期：2015-12-15 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2006.03.002
更新日期：2007-08-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(95)02788-2
更新日期：1995-11-29 00:00:00
abstract：:While hallucinations have been described for over two millennia, their cause remains unclear. Brain-based models suggest that abnormal cerebral excitation and a lack of normal cerebral inhibition may play primary roles, but evaluation of these hypotheses has been hampered by difficulty in studying the hallucinatory st...
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pub_type： 杂志文章,评审
doi：10.1016/s0925-4927(99)00041-4
更新日期：1999-12-20 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2010.10.012
更新日期：2011-05-15 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(89)90148-0
更新日期：1989-03-01 00:00:00
abstract：:Thirty depressed patients were compared with 39 controls for their plasma norepinephrine (NE) levels in relation to a cold challenge (placing a hand in ice cold water for 1 minute). Depressed patients showed significantly higher plasma NE levels than controls. Unipolar, but not bipolar patients, had significantly high...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(87)90073-4
更新日期：1987-06-01 00:00:00
abstract：:Mental illness is associated with unfair treatment in a number of areas of life. There is currently no psychometrically validated measure that has been developed to specifically focus on such experienced discrimination. This study aimed to finalise the Discrimination and Stigma Scale (DISC) and establish its psychomet...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2013.03.007
更新日期：2013-06-30 00:00:00
