Update on Obesity and Obesity Paradox in Heart Failure.

Abstract:

:Obesity has reached epidemic proportions in most of the Westernized world. Overweightness and obesity adversely impact cardiac structure and function, including on both the right and, especially, left sides of the heart, with adverse affects on systolic and, especially, diastolic ventricular function. Therefore, it is not surprising that obesity markedly increases the prevalence of heart failure (HF). Nevertheless, many studies have documented an obesity paradox in large cohorts with HF, where overweight and obese have a better prognosis, at least in the short-term, compared with lean HF patients. Although weight loss clearly improves cardiac structure and function and reduces symptoms in HF, there are no large studies on the impact of weight loss on clinical events in HF, preventing definitive guidelines on optimal body composition in patients with HF.

journal_name

Prog Cardiovasc Dis

authors

Lavie CJ,Sharma A,Alpert MA,De Schutter A,Lopez-Jimenez F,Milani RV,Ventura HO

doi

10.1016/j.pcad.2015.12.003

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

393-400

issue

4

eissn

0033-0620

issn

1873-1740

pii

S0033-0620(15)30029-3

journal_volume

58

pub_type

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