Baroreflex function in hypertension: consequences for antihypertensive therapy.

Abstract:

:Studies performed in experimental animal models of hypertension as well as in human hypertension have unequivocally shown that reflex cardiovascular control undergoes profound changes with high blood pressure and participates throughout direct and indirect mechanisms at the development and progression of hypertension-related target organ damage. This explains why investigation of the effects of antihypertensive drugs on neural cardiovascular control has a significant impact on hypertension treatment. This review will examine the main features of cardiovascular reflex control in hypertension and the effects of the different classes of antihypertensive drugs in uncomplicated and complicated hypertension.

journal_name

Prog Cardiovasc Dis

authors

Grassi G,Trevano FQ,Seravalle G,Scopelliti F,Mancia G

doi

10.1016/j.pcad.2006.03.002

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

407-15

issue

6

eissn

0033-0620

issn

1873-1740

pii

S0033-0620(06)00024-7

journal_volume

48

pub_type

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