Abstract:
:Pulmonary hypertension (PH) in the setting of left side heart disease is associated with adverse outcomes. The exact prevalence of PH in the different pathologies that affect the left ventricle, however, is difficult to access with the current literature. The lack of a standard definition of PH in older studies, the different modalities to assess pulmonary artery pressures and the varying disease severity, all account for the great variability in the reported prevalence of PH. PH can accompany heart failure (HF) with reduced (HFrEF) or preserved ejection fraction (HFpEF) as well as mitral and aortic valve disease; in any of these instances it is important to recognize whether the elevation of pulmonary pressures is driven by elevated left ventricular pressures only (isolated post-capillary PH) or if there is an accompanying remodeling component in the pulmonary arterioles (combined post-capillary and pre-capillary PH). The objective of this review is to describe the definitions, prevalence and the risk factors associated with the development of PH in the setting of HFrEF, HFpEF and valvular heart disease.
journal_name
Prog Cardiovasc Disjournal_title
Progress in cardiovascular diseasesauthors
Guha A,Amione-Guerra J,Park MHdoi
10.1016/j.pcad.2016.07.001subject
Has Abstractpub_date
2016-07-01 00:00:00pages
3-10issue
1eissn
0033-0620issn
1873-1740pii
S0033-0620(16)30053-6journal_volume
59pub_type
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