Abstract：
:Over the past decade, emerging clinical trial data supported the usefulness of implanted therapeutic cardiac devices (pacemakers and defibrillators) for the treatment of heart failure (HF). Interest has now developed in evaluating the potential of device diagnostics to identify HF patients at risk for clinical events and to be used in the management of HF patients. Initial studies have provided inconsistent results. A number of trial design elements have likely played a role in the lack of positive results, including cohort risk determination, intensity of usual care, intensity of the intervention, and selection of end points for the study. These issues will be important to understand when evaluating future clinical trial results and developing new studies, particularly in other HF patient cohorts such as HF with preserved left ventricular function.
journal_name
Prog Cardiovasc Disjournal_title
Progress in cardiovascular diseasesauthors
Whellan DJ,Adams S,Bowerman Ldoi
10.1016/j.pcad.2011.06.001subject
Has Abstractpub_date
2011-09-01 00:00:00pages
107-14issue
2eissn
0033-0620issn
1873-1740pii
S0033-0620(11)00125-3journal_volume
54pub_type
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