Mechanisms of atrial fibrillation: lessons from studies in patients.

Abstract:

:Recent clinical studies performed in human subjects have provided important clues that improved our understanding of the mechanisms of atrial fibrillation (AF) and facilitated development of new treatment strategies. When analyzed together, these studies confirm the complexity and multifactorial nature of AF. Because a variety of mechanisms such as focal drivers within the thoracic veins, rotors in the left atrium, multiple reentrant circuits, and autonomic innervation may play a role in the initiation and maintenance of AF alone or in combination, the best strategy to eliminate AF may be the accurate identification of one or more of the mechanisms critical to the genesis of AF and to target the specific mechanism(s).

journal_name

Prog Cardiovasc Dis

authors

Oral H

doi

10.1016/j.pcad.2005.06.003

subject

Has Abstract

pub_date

2005-07-01 00:00:00

pages

29-40

issue

1

eissn

0033-0620

issn

1873-1740

pii

S0033-0620(05)00030-7

journal_volume

48

pub_type

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