The Challenge of Analyzing the Results of Next-Generation Sequencing in Children.

abstract：OBJECTIVE:This study evaluated age- and sedative agent-related differences in bispectral index across observed sedation levels in a large sample of children < 18 years of age. PATIENTS AND METHODS:With institutional review board approval and waiver of consent, data from 4 independently conducted studies were combined ...

journal_title：Pediatrics

authors： Malviya S,Voepel-Lewis T,Tait AR,Watcha MF,Sadhasivam S,Friesen RH

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:To compare 17-hydroxyprogesterone (17-OHP) levels measured by quantitative serum radioimmunoassay (RIA), including an extraction step, and by screening fluoroimmunoassay (FIA) on blood spots in preterm infants. METHODS:Subjects were 39 healthy infants born at less than 31 weeks' gestational age. Each infant ...

journal_title：Pediatrics

authors： al Saedi S,Dean H,Dent W,Stockl E,Cronin C

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVES:The association between parent-reported postnatal secondhand tobacco smoke exposure in the home and neurobehavioral disorders (attention-deficit/hyperactivity disorder, learning disabilities, and conduct disorders) among children younger than 12 years in the United States was examined using the 2007 National...

journal_title：Pediatrics

authors： Kabir Z,Connolly GN,Alpert HR

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:The role of laparoscopic surgery in pediatric inguinal hernia repair is unclear. We aimed to compare day-case laparoscopic hernia repair with open repair. METHODS:A prospective, single-blinded randomized study in children aged 4 months to 16 years with unilateral inguinal hernia was performed. The primary ou...

journal_title：Pediatrics

authors： Koivusalo AI,Korpela R,Wirtavuori K,Piiparinen S,Rintala RJ,Pakarinen MP

更新日期：2009-01-01 00:00:00

abstract：:This statement provides current recommendations about the use of emergency drugs for acute pediatric problems that require pharmacologic intervention. At each clinical setting, physicians and other providers should evaluate drug, equipment, and training needs. The information provided here is not all-inclusive and is ...

journal_title：Pediatrics

authors：

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between breastfeeding and the risk of life-threatening enterotoxigenic Escherichia coli (ETEC) diarrhea among Bangladeshi infants and young children <36 months of age. DESIGN:Case-control study. SETTING:A rural Bangladesh community. PARTICIPANTS:A total of 168 cases with clinical...

journal_title：Pediatrics

authors： Clemens JD,Rao MR,Chakraborty J,Yunus M,Ali M,Kay B,van Loon FPL,Naficy A,Sack DA

更新日期：1997-12-01 00:00:00

abstract：:The American Academy of Pediatrics recognizes that exposure to mass media (eg, television, movies, video and computer games, the Internet, music lyrics and videos, newspapers, magazines, books, advertising) presents health risks for children and adolescents but can provide benefits as well. Media education has the pot...

journal_title：Pediatrics

authors： Strasburger VC,Council on Communications and Media American Academy of Pediatrics.

更新日期：2010-11-01 00:00:00

abstract：:Deep venous thrombosis is a frequent, well-recognized complication of spinal cord injury. Patients with myelomeningocele often have similar weakness of the lower extremities. Following orthopedic surgery, they may also be immobilized at a time when they are hypercoagulable. In addition, as with patients with spinal co...

journal_title：Pediatrics

authors： Bernstein ML,Esseltine D,Azouz EM,Forbes P

更新日期：1989-11-01 00:00:00

abstract：:Survival of motor neuron 1-------negative spinal muscular atrophy (SMA) is heterogeneous and remains a diagnostic challenge. The clinical spectrum continues to expand and ∼33 genes have been identified to date. The present report describes a 9-year-old girl with novel clinical phenotype of a patient with polyarticular...

journal_title：Pediatrics

authors： Teoh HL,Solyom A,Schuchman EH,Mowat D,Roscioli T,Farrar M,Sampaio H

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Sexual assault is a major cause of injury, unplanned pregnancy, HIV infection, and mental health problems worldwide. In parts of sub-Saharan Africa, sexual assault has reached epidemic proportions. This study evaluated the efficacy of an empowerment and self-defense intervention for adolescent ...

journal_title：Pediatrics

authors： Sarnquist C,Omondi B,Sinclair J,Gitau C,Paiva L,Mulinge M,Cornfield DN,Maldonado Y

更新日期：2014-05-01 00:00:00

abstract：:Self-assessments of 133 parents' (74 families) feelings, perceptions, reactions to stresses, and satisfactions during a period of electronic home monitoring are reported. Data were collected during structured interviews by students in a graduate social work program. Although extreme anxiety was prevalent initially, on...

journal_title：Pediatrics

authors： Cain LP,Kelly DH,Shannon DC

更新日期：1980-07-01 00:00:00

abstract：:Since the American Academy of Pediatrics published guidelines for pediatric cancer centers in 1986 and 1997, significant changes in the delivery of health care have prompted a review of the role of tertiary medical centers in the care of pediatric patients. The potential effect of these changes on the treatment and su...

journal_title：Pediatrics

authors： Corrigan JJ,Feig SA,American Academy of Pediatrics.

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:This study examines the relationship of intrauterine growth, measured by size and maturity at birth, to age at menarche, while also considering a wide range of other factors that may affect maturation. The research is motivated by the current debate about the importance of the prenatal environment as a determ...

journal_title：Pediatrics

authors： Adair LS

更新日期：2001-04-01 00:00:00

abstract：:The relationship between heavy drinking during pregnancy and congenital malformations is well known; however, whether moderate or light drinking is teratogenic is controversial. This prospective birth defects study collected information from 32,870 women about alcohol consumption during the first trimester of pregnanc...

journal_title：Pediatrics

authors： Mills JL,Graubard BI

更新日期：1987-09-01 00:00:00

abstract：:To improve child health at a community level, pediatricians require knowledge and skills that have not been traditionally included in residency training. Recent policy statements from the American Academy of Pediatrics and requirements from Accreditation Council for Graduate Medical Education Residency Review committe...

journal_title：Pediatrics

authors： Shipley LJ,Stelzner SM,Zenni EA,Hargunani D,O'Keefe J,Miller C,Alverson B,Swigonski N

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Recent children's health surveys have documented a high prevalence of emotional, developmental, and behavioral problems among children. Data from the 2003 National Survey of Children's Health provide new insights into these problems and their association with family function and community participation. Thes...

journal_title：Pediatrics

authors： Blanchard LT,Gurka MJ,Blackman JA

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:Berardinelli-Seip syndrome is a rare congenital lipoatrophy with a severe prognosis and no efficient therapy. Children present with low leptin levels and severe metabolic complications (insulin resistance, elevated triglyceride levels, and hepatic steatosis). The objective of this study was to test safety and...

journal_title：Pediatrics

authors： Beltrand J,Beregszaszi M,Chevenne D,Sebag G,De Kerdanet M,Huet F,Polak M,Tubiana-Rufi N,Lacombe D,De Paoli AM,Levy-Marchal C

更新日期：2007-08-01 00:00:00

abstract：:In summary: (1) Colestipol therapy plus diet reduced total cholesterol 19 +/- 3% in 11 hypercholesterolemic children after two months and 13 +/- 5% after two years in five children. (2) Diet therapy did not significantly reduce serum concentration of any of the fat-soluble vitamins or folate. (3) During 24 months of c...

journal_title：Pediatrics

authors： Schwarz KB,Goldstein PD,Witztum JL,Schonfeld G

更新日期：1980-02-01 00:00:00

abstract：:Echocardiographic evaluation of left ventricular (LV) performance was performed in 41 children during and following anthracycline chemotherapy. Prior to treatment LV function was normal in all patients; LV shortening fraction was 35.2 +/- 0.7% and percent of predicted velocity of circumferential fiber shortening was 1...

journal_title：Pediatrics

authors： Lewis AB,Crouse VL,Evans W,Takahashi M,Siegel SE

更新日期：1981-07-01 00:00:00

abstract：OBJECTIVE:We tested the hypothesis that survival is highest for infants born in the same weight range whether mothers are adolescent or adult, comparing the weights at which infants of these mothers achieve lowest neonatal mortality. METHODS:The relationship between birth weight and neonatal mortality was studied in b...

journal_title：Pediatrics

authors： Rees JM,Lederman SA,Kiely JL

更新日期：1996-12-01 00:00:00

abstract：:Antibiotic overuse contributes to antibiotic resistance, which is a threat to public health. Antibiotic stewardship is a practice dedicated to prescribing antibiotics only when necessary and, when antibiotics are considered necessary, promoting use of the appropriate agent(s), dose, duration, and route of therapy to o...

journal_title：Pediatrics

authors： Gerber JS,Jackson MA,Tamma PD,Zaoutis TE,COMMITTEE ON INFECTIOUS DISEASES, PEDIATRIC INFECTIOUS DISEASES SOCIETY.

更新日期：2021-01-01 00:00:00

abstract：:The place of causal inference in clinical practice is considered. One function relates to the validation of existing knowledge, as in the evaluation of the medical literature, and is exemplified by the process of editorial selection. A second function relates to the validation of potential knowledge, as in the testing...

journal_title：Pediatrics

authors： Susser M

更新日期：1984-11-01 00:00:00

abstract：OBJECTIVE:Currently, the methods for assessing milk ejection in women include serial sampling of plasma oxytocin and measurement of intraductal pressure, both of which are invasive and may induce stress. We hypothesized that milk ejection would cause an increase in milk-duct diameter that could be observed noninvasivel...

journal_title：Pediatrics

authors： Ramsay DT,Kent JC,Owens RA,Hartmann PE

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:To improve the frequency of electronic prescribing (e-prescribing) of discharge prescriptions at a children's hospital via a bundle of quality improvement interventions. METHODS:Surveys and focus groups were conducted with patient families and pediatric residents to identify barriers and propose solutions to...

journal_title：Pediatrics

authors： Fuchs J,Lo HY,Peterman A,Camp E,Chase L

更新日期：2016-11-01 00:00:00

abstract：:Infants born to women who are asymptomatic hepatitis B surface antigen (HBsAg) carriers frequently acquire hepatitis B virus infection in infancy. The spectrum of disease in such affected infants includes mild transient acute hepatitis B, chronic active hepatitis with or without cirrhosis, chronic persistent hepatitis...

journal_title：Pediatrics

authors： Delaplane D,Yogev R,Crussi F,Shulman ST

更新日期：1983-08-01 00:00:00

abstract：:Laparoscopy has been performed in 120 infants and children for a variety of indications including chronic abdominal pain, debatable appendicitis, liver biopsy, biliary atresia, and abdominal trauma. A specific diagnosis was made in 71% of patients and 59% were spared laparotomy. There were one complication and four er...

journal_title：Pediatrics

authors： Leape LL,Ramenofsky ML

更新日期：1980-08-01 00:00:00

abstract：OBJECTIVES:To compare the detection of facial attributes by computer-based facial recognition software of 2-D images against standard, manual examination in fetal alcohol spectrum disorders (FASD). METHODS:Participants were gathered from the Fetal Alcohol Syndrome Epidemiology Research database. Standard frontal and o...

journal_title：Pediatrics

authors： Valentine M,Bihm DCJ,Wolf L,Hoyme HE,May PA,Buckley D,Kalberg W,Abdul-Rahman OA

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:2-methylbutyryl-CoA dehydrogenase deficiency, also known as short/branched-chain acyl-CoA dehydrogenase (SBCAD) deficiency, is a recently described autosomal recessive disorder of L-isoleucine metabolism. Only 4 affected individuals in 2 families have been described. One patient developed athetoid cerebral pa...

journal_title：Pediatrics

authors： Matern D,He M,Berry SA,Rinaldo P,Whitley CB,Madsen PP,van Calcar SC,Lussky RC,Andresen BS,Wolff JA,Vockley J

更新日期：2003-07-01 00:00:00

abstract：:These are case reports of two children with structurally normal hearts and with normal coronary arteries, who survived myocardial infarction in the early neonatal period. They are only the third and fourth reported survivors of neonatal myocardial infarction and the first in which hypercholesterolemia is postulated to...

journal_title：Pediatrics

authors： Boulton J,Henry R,Roddick LG,Rogers D,Thompson L,Warner G

更新日期：1991-07-01 00:00:00

abstract：OBJECTIVES:Adolescents with justice system involvement have high rates of physical and behavioral health disorders and are potentially high users of costly health care services. We examined emergency department (ED) and hospital use among a national sample of adolescents with various levels of justice involvement. MET...

journal_title：Pediatrics

authors： Winkelman TNA,Genao I,Wildeman C,Wang EA

更新日期：2017-11-01 00:00:00