Causal thinking in practice: strengths and weaknesses of the clinical vantage point.

Abstract:

:The place of causal inference in clinical practice is considered. One function relates to the validation of existing knowledge, as in the evaluation of the medical literature, and is exemplified by the process of editorial selection. A second function relates to the validation of potential knowledge, as in the testing of hypotheses, and is exemplified by the pursuit of a nutritional cause of retarded mental development. Features of clinical practice that contribute strengths or weaknesses to causal inference are then examined. These include the diagnostic process, the effect of cumulative clinical experience, continuity of observation and follow-up, and the focus on disease.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Susser M

subject

Has Abstract

pub_date

1984-11-01 00:00:00

pages

842-9

issue

5

eissn

0031-4005

issn

1098-4275

journal_volume

74

pub_type

杂志文章
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    abstract:BACKGROUND:Adults frequently seek medical services in children's hospital emergency departments (CHEDs), and are required to be admitted to CHEDs under the provisions of the Emergency Medical Transfer and Active Labor Act (EMTALA), which requires medical evaluation and stabilization of every patient who presents to an ...

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    doi:10.1542/peds.111.6.1268

    authors: Bourgeois FT,Shannon MW

    更新日期:2003-06-01 00:00:00

  • Spermatic cord torsion: diagnostic limitations.

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    authors: Stoller ML,Kogan BA,Hricak H

    更新日期:1985-12-01 00:00:00

  • Arkansas' experience: statewide surveillance and parental information on the child obesity epidemic.

    abstract::Parents, clinicians, public health officials, and policy makers need readily available information on the extent of the childhood obesity epidemic. As in any epidemic, the strategies and tools used to combat the imminent threat are frequently based on scientific rationale and experience but applied in areas in which w...

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    doi:10.1542/peds.2008-3586J

    authors: Thompson JW,Card-Higginson P

    更新日期:2009-09-01 00:00:00

  • American Academy of Pediatrics: Medical conditions affecting sports participation.

    abstract::Children and adolescents with medical conditions present special issues with respect to participation in athletic activities. The pediatrician can play an important role in determining whether a child with a health condition should participate in certain sports by assessing the child's health status, suggesting approp...

    journal_title:Pediatrics

    pub_type: 指南,杂志文章

    doi:10.1542/peds.107.5.1205

    authors: Committee on Sports Medicine and Fitness.

    更新日期:2001-05-01 00:00:00

  • On the front lines: lessons learned in implementing multidisciplinary peripheral venous access pain-management programs in pediatric hospitals.

    abstract::Venipuncture and intravenous cannulation are among the most common and widespread medical procedures performed on children today. Therefore, effective treatment of venous access pain can benefit from an integrated systems approach that enlists multiple players in the health care system. By using case studies that anal...

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    doi:10.1542/peds.2008-1055i

    authors: Leahy S,Kennedy RM,Hesselgrave J,Gurwitch K,Barkey M,Millar TF

    更新日期:2008-11-01 00:00:00

  • Prolonged neonatal jaundice and the diagnosis of biliary atresia: a single-center analysis of trends in age at diagnosis and outcomes.

    abstract::Age at diagnosis is a modifiable risk factor in outcomes after hepatoportoenterostomy in biliary atresia; however, distinguishing biliary atresia from other more common causes of prolonged neonatal jaundice can be difficult. To focus attention on diagnosis of biliary atresia, we analyzed secular trends in the age at d...

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    doi:10.1542/peds.2007-2709

    authors: Wadhwani SI,Turmelle YP,Nagy R,Lowell J,Dillon P,Shepherd RW

    更新日期:2008-05-01 00:00:00

  • Herpes simplex virus central nervous system relapse during treatment of infantile spasms with corticotropin.

    abstract::Here we report an infant who had herpes simplex virus (HSV) encephalitis and sustained severe bilateral damage to the posterior frontal lobes, postcentral gyri, and the thalami despite intravenous acyclovir treatment. At 7 months of age, the patient developed infantile spasms and was treated with corticotropin injecti...

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    doi:10.1542/peds.2005-1867

    authors: Bonkowsky JL,Filloux FM,Byington CL

    更新日期:2006-05-01 00:00:00

  • Pneumococcal mastoiditis in children.

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    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.106.4.695

    authors: Kaplan SL,Mason EO Jr,Wald ER,Kim KS,Givner LB,Bradley JS,Barson WJ,Tan TQ,Schutze GE,Yogev R

    更新日期:2000-10-01 00:00:00

  • Laparoscopic diagnosis and cure of hyperinsulinism in two cases of focal adenomatous hyperplasia in infancy.

    abstract::Persistent hyperinsulinemic hypoglycemia of infancy or congenital hyperinsulinism of the neonate is a rare condition that may cause severe neurologic damage if the disease is unrecognized or inadequately treated. Current treatment aims to restore normal blood glucose levels by providing a carbohydrate-enriched diet an...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2003-1180-L

    authors: De Vroede M,Bax NM,Brusgaard K,Dunne MJ,Groenendaal F

    更新日期:2004-10-01 00:00:00

  • Decreasing PICU catheter-associated bloodstream infections: NACHRI's quality transformation efforts.

    abstract:OBJECTIVE:Despite the magnitude of the problem of catheter-associated bloodstream infections (CA-BSIs) in children, relatively little research has been performed to identify effective strategies to reduce these complications. In this study, we aimed to develop and evaluate effective catheter-care practices to reduce pe...

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    pub_type: 杂志文章,多中心研究

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    authors: Miller MR,Griswold M,Harris JM 2nd,Yenokyan G,Huskins WC,Moss M,Rice TB,Ridling D,Campbell D,Margolis P,Muething S,Brilli RJ

    更新日期:2010-02-01 00:00:00

  • Clinical and virologic features of hepatitis C virus infection associated with intravenous immunoglobulin.

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    pub_type: 杂志文章

    doi:

    authors: Jonas MM,Baron MJ,Bresee JS,Schneider LC

    更新日期:1996-08-01 00:00:00

  • Diaper need and its impact on child health.

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    doi:10.1542/peds.2013-0597

    authors: Smith MV,Kruse A,Weir A,Goldblum J

    更新日期:2013-08-01 00:00:00

  • Cholestasis and Hepatic Iron Deposition in an Infant With Complex Glycerol Kinase Deficiency.

    abstract::We present a 6-week-old male infant with persistent hyperbilirubinemia, hypertriglyceridemia, elevated creatine kinase levels, and transaminitis since the second week of life. When he developed hyperkalemia, clinical suspicion was raised for adrenal insufficiency despite hemodynamic stability. A full endocrine workup ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-1479

    authors: Montoya-Williams D,Mowitz M

    更新日期:2017-07-01 00:00:00

  • Urinary tract infection in febrile infants younger than eight weeks of Age.

    abstract:OBJECTIVE:To assess the usefulness of laboratory parameters, including peripheral white blood cell (WBC) count, C-reactive protein (CRP) concentration, erythrocyte sedimentation rate (ESR), and microscopic urinalysis (UA), for identifying febrile infants younger than 8 weeks of age at risk for urinary tract infection (...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.105.2.e20

    authors: Lin DS,Huang SH,Lin CC,Tung YC,Huang TT,Chiu NC,Koa HA,Hung HY,Hsu CH,Hsieh WS,Yang DI,Huang FY

    更新日期:2000-02-01 00:00:00

  • Long-term follow-up of 2 newborns with a combined birth weight of 540 grams.

    abstract::Long-term growth and developmental data are presented for the smallest and third smallest surviving newborns in the world literature to 5 and 20 years of age, respectively. Both patients exhibited normal motor and language development. Although head circumference for both newborns demonstrated catchup growth, signific...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-0039

    authors: Muraskas JK,Rau BJ,Castillo PR,Gianopoulos J,Boyd LA

    更新日期:2012-01-01 00:00:00

  • Palivizumab, a Humanized Respiratory Syncytial Virus Monoclonal Antibody, Reduces Hospitalization From Respiratory Syncytial Virus Infection in High-risk Infants.

    abstract::Objective. To determine the safety and efficacy of prophylaxis with palivizumab in reducing the incidence of hospitalization because of respiratory syncytial virus (RSV) infection in high-risk infants. Methods. A randomized, double-blind, placebo-controlled trial was conducted at 139 centers in the United States, the ...

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    pub_type: 杂志文章

    doi:

    authors:

    更新日期:1998-09-01 00:00:00

  • A population-based, postlicensure evaluation of the safety of a combination diphtheria, tetanus, acellular pertussis, hepatitis B, and inactivated poliovirus vaccine in a large managed care organization.

    abstract:BACKGROUND:Prelicensure studies of diphtheria, tetanus, acellular pertussis, hepatitis B, inactivated polio virus vaccine suggested that there were higher rates of fever after its administration than when its component antigens were given separately. METHODS:We conducted an open, controlled, cohort study to evaluate s...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-1977

    authors: Zangwill KM,Eriksen E,Lee M,Lee J,Marcy SM,Friedland LR,Weston W,Howe B,Ward JI

    更新日期:2008-12-01 00:00:00

  • Recent trends in waist circumference and waist-height ratio among US children and adolescents.

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    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-1062

    authors: Li C,Ford ES,Mokdad AH,Cook S

    更新日期:2006-11-01 00:00:00

  • A Sports-Based Youth Development Program, Teen Mental Health, and Physical Fitness: An RCT.

    abstract:OBJECTIVES:To assess the effectiveness of a positive youth development (PYD)-based sports mentorship program on the physical and mental well-being of adolescents recruited in a community setting. METHODS:This is a randomized controlled trial in which we recruited students from 12 secondary schools in Hong Kong, China....

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2017-1543

    authors: Ho FKW,Louie LHT,Wong WH,Chan KL,Tiwari A,Chow CB,Ho W,Wong W,Chan M,Chen EYH,Cheung YF,Ip P

    更新日期:2017-10-01 00:00:00

  • Impact of maternal diabetes mellitus on mortality and morbidity of preterm infants (24-33 weeks' gestation).

    abstract:OBJECTIVE:We hypothesized that maternal diabetes mellitus (DM) increases the risk for mortality, respiratory distress syndrome (RDS), and major complications of prematurity. METHODS:Analysis of prospectively collected (1995-2007) Israel National Very Low Birth Weight Infant Database. Maternal DM was recorded as preges...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-3443

    authors: Bental Y,Reichman B,Shiff Y,Weisbrod M,Boyko V,Lerner-Geva L,Mimouni FB,Collaboration With the Israel Neonatal Network.

    更新日期:2011-10-01 00:00:00

  • Race, otitis media, and antibiotic selection.

    abstract:BACKGROUND AND OBJECTIVE:Previous research suggests that physicians may be less likely to diagnose otitis media (OM) and to prescribe broad-spectrum antibiotics for black versus nonblack children. Our objective was to determine whether race is associated with differences in OM diagnosis and antibiotic prescribing natio...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2014-1781

    authors: Fleming-Dutra KE,Shapiro DJ,Hicks LA,Gerber JS,Hersh AL

    更新日期:2014-12-01 00:00:00

  • Stakeholder Perspectives on Research and Practice in Autism and Transition.

    abstract:OBJECTIVES:Individuals with autism spectrum disorder (ASD) are reported to experience significant challenges during the transition to adulthood. Although recent evidence indicates that individuals with ASD experience poor outcomes in adulthood, little is understood about the contributing factors. In this qualitative st...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-4300F

    authors: Kuo AA,Crapnell T,Lau L,Anderson KA,Shattuck P

    更新日期:2018-04-01 00:00:00

  • The emergency physician and the office-based pediatrician: an EMSC team. American Academy of Pediatrics. Committee on Pediatric Emergency Medicine.

    abstract::In a quality and cost-conscious health care environment, the pediatrician and emergency physician must work as a team. This statement clarifies important issues of this relationship, including coordination of patient care, communication between clinicians, provision of continuity care, and responsibility for quality e...

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    pub_type: 杂志文章

    doi:10.1542/peds.101.5.936

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  • Perinatal manifestations of maternal yellow nail syndrome.

    abstract::A term female firstborn infant had unexplained nonimmune fetal hydrops and recurrent left chylothorax at 4 weeks of age. A few months before conception, her mother had had acute dystrophic nail changes and is being treated for recurrent sinusitis, bronchiectasis, and a deficiency of serum IgG2. We suggest that they bo...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Govaert P,Leroy JG,Pauwels R,Vanhaesebrouck P,De Praeter C,Van Kets H,Goeteyn M

    更新日期:1992-06-01 00:00:00

  • Timing of adiposity rebound and adiposity in adolescence.

    abstract:OBJECTIVES:To investigate associations between timing of adiposity rebound (AR; the period in childhood where BMI begins to increase from its nadir) and adiposity (BMI, fat mass) at age 15 years in the Avon Longitudinal Study of Parents and Children (ALSPAC). METHODS:The sample consisted of 546 children with AR derive...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2014-1908

    authors: Hughes AR,Sherriff A,Ness AR,Reilly JJ

    更新日期:2014-11-01 00:00:00

  • Medication errors in pediatric inpatients: prevalence and results of a prevention program.

    abstract:OBJECTIVE:The objective of this study was to assess the prevalence and characteristics of medication errors in pediatric and neonatal inpatients and to measure the impact of interventions to reduce medication errors. METHODS:A preintervention and postintervention cross-sectional study was conducted of a sample of pres...

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    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2008-0014

    authors: Otero P,Leyton A,Mariani G,Ceriani Cernadas JM,Patient Safety Committee.

    更新日期:2008-09-01 00:00:00

  • International Variability in Gastrointestinal Decontamination With Acute Poisonings.

    abstract:BACKGROUND AND OBJECTIVES:Identifying international differences in the management of acute pediatric poisonings may help improve the quality of care. The objective of this study was to assess the international variation and appropriateness of gastrointestinal decontamination (GID) procedures performed in children and a...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2017-0006

    authors: Mintegi S,Dalziel SR,Azkunaga B,Prego J,Arana-Arri E,Acedo Y,Martinez-Indart L,Benito J,Kuppermann N,Pediatric Emergency Research Networks (PERN) Poisoning Working Group.

    更新日期:2017-08-01 00:00:00

  • Simulation in Pediatric Emergency Medicine Fellowships.

    abstract:BACKGROUND AND OBJECTIVES:Graduate medical education faces challenges as programs transition to the next accreditation system. Evidence supports the effectiveness of simulation for training and assessment. This study aims to describe the current use of simulation and barriers to its implementation in pediatric emergenc...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2014-4158

    authors: Doughty CB,Kessler DO,Zuckerbraun NS,Stone KP,Reid JR,Kennedy CS,Nypaver MM,Auerbach MA

    更新日期:2015-07-01 00:00:00

  • Endemic iron deficiency associated with Helicobacter pylori infection among school-aged children in Alaska.

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    pub_type: 杂志文章

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    authors: Baggett HC,Parkinson AJ,Muth PT,Gold BD,Gessner BD

    更新日期:2006-03-01 00:00:00

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    doi:10.1542/peds.103.4.766

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    更新日期:1999-04-01 00:00:00