Abstract:
:Persistent hyperinsulinemic hypoglycemia of infancy or congenital hyperinsulinism of the neonate is a rare condition that may cause severe neurologic damage if the disease is unrecognized or inadequately treated. Current treatment aims to restore normal blood glucose levels by providing a carbohydrate-enriched diet and drugs that inhibit insulin secretion. If medical treatment fails, then surgery is required. Because congenital hyperinsulinism may be caused either by diffuse involvement of pancreatic beta-cells or by a focal cluster of abnormal beta-cells, the extent of pancreatectomy varies. We report on 2 patients with a focal form of the disease for whom diagnosis was made with laparoscopy. Laparoscopic enucleation of the lesion was curative.
journal_name
Pediatricsjournal_title
Pediatricsauthors
De Vroede M,Bax NM,Brusgaard K,Dunne MJ,Groenendaal Fdoi
10.1542/peds.2003-1180-Lsubject
Has Abstractpub_date
2004-10-01 00:00:00pages
e520-2issue
4eissn
0031-4005issn
1098-4275pii
114/4/e520journal_volume
114pub_type
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