Botulinum Toxin Therapy for Parkinson's Disease.

abstract：:CPP reflects perfusion problems related to increased ICP or inadequate MAP. CPP is a most helpful and practical management tool. The relationship of CBF and CPP depends on cerebral vascular resistance (flow equals pressure divided by resistance). At present, we do not have a practical method to measure vascular resist...

journal_title：Seminars in neurology

authors： Stone JL

更新日期：1989-09-01 00:00:00

abstract：:Synucleinopathies, with and without dementia, encompass a wide range of diseases including Parkinson's disease, multiple system atrophy, rapid eye movement (REM) sleep behavior disorder, and dementia with Lewy bodies (DLB). DLB is a neurodegenerative disorder resulting in slowly progressive and unrelenting dementia un...

journal_title：Seminars in neurology

authors： Weisman D,McKeith I

更新日期：2007-02-01 00:00:00

abstract：:Stroke in the distribution of the posterior circulation may present as acute onset spontaneous vertigo and imbalance. Although vertigo due to posterior circulation stroke is usually associated with other neurologic symptoms or signs, small infarcts in the cerebellum or brainstem can present with vertigo without other ...

journal_title：Seminars in neurology

authors： Kim JS,Lee H

更新日期：2013-07-01 00:00:00

abstract：:The accumulation of fibrillar α-synuclein protein is the pathological hallmark occurring in both multiple system atrophy (MSA) and diffuse Lewy body disease (DLBD). The oligodendrocytes are especially involved in MSA, while subtypes of neurons are the targets in DLBD. In both instances, the changes are widespread with...

journal_title：Seminars in neurology

authors： Ramirez EP,Vonsattel JP

更新日期：2014-04-01 00:00:00

abstract：:Autoimmune epilepsy is increasingly recognized as a distinct clinical entity, driven in large part by the recent discovery of neural autoantibodies in patients with isolated or predominant epilepsy presentations. Detection of neural autoantibodies in high-risk epilepsy patients supports an immune-mediated cause of sei...

journal_title：Seminars in neurology

authors： Quek AML,O'Toole O

更新日期：2018-06-01 00:00:00

abstract：:Treatment of dementias represents an important but relatively neglected part of neurological care of the elderly population. Individual therapeutic interventions may make only small changes to the quality of life of individuals afflicted with dementia, but when used in combination these interventions synergize and can...

journal_title：Seminars in neurology

authors： Tisher A,Salardini A

更新日期：2019-04-01 00:00:00

abstract：:The muscular dystrophies are disorders of progressive muscular degeneration and weakness. As a group they display clinical heterogeneity that reflects the heterogeneity of molecular mechanisms responsible for them, and range from congenital to adulthood onset. Recent advances in the field include improved methods of d...

journal_title：Seminars in neurology

authors： Flanigan KM

更新日期：2012-07-01 00:00:00

abstract：:The diagnosis of inherited neuropathies can be challenging in several ways. First, a hereditary neuropathy must be suspected. Although some family histories are clear with multiple members affected, other families require directed inquiry. Second, even when a hereditary neuropathy is clear, it can be difficult to make...

journal_title：Seminars in neurology

authors： Lawson V,Gharibshahi S

更新日期：2010-09-01 00:00:00

abstract：:Telemedicine is the use of electronic communication methods, such as the telephone, the Internet, and videoconferencing, to exchange medical information from one geographic site to another. Telestroke is the use of telemedicine specifically for stroke care. A strokologist is a physician with the special skills require...

journal_title：Seminars in neurology

authors： Demaerschalk BM

更新日期：2010-11-01 00:00:00

abstract：:Parkinson's disease (PD) is a significant neurodegenerative disease of the elderly, affecting 1 to 2% of those over 60 years of age. The disorder is characterized by resting tremor, bradykinesia, rigidity, postural instability, and pathologically by alpha-synuclein-positive Lewy bodies. For most, the etiology is unkno...

journal_title：Seminars in neurology

authors： Lorincz MT

更新日期：2006-11-01 00:00:00

abstract：:The clinical evaluation of peripheral neuropathies can be challenging. This article presents an approach based on a structured assessment that asks a series of yes or no questions during the history and examination that leads to localization and characterization of the neuropathy. The final assessment includes further...

journal_title：Seminars in neurology

authors： Bromberg MB

更新日期：2005-06-01 00:00:00

abstract：:Lightning and electrical injuries have widespread manifestations involving almost all organ systems of the body, including the central nervous system (CNS) and the eye. This article considers the neuro-ophthalmologic effects of lightning and electrical injury. ...

journal_title：Seminars in neurology

authors： Grover S,Goodwin J

更新日期：1995-12-01 00:00:00

abstract：:The vast majority of people living with human immunodeficiency virus (HIV) infection reside in resource-limited settings. As compared with resource-rich settings, there are important differences in the epidemiology and outcomes of HIV infection in resource-limited settings. Nonetheless, little HIV neurology research o...

journal_title：Seminars in neurology

authors： Meyer AC

更新日期：2014-02-01 00:00:00

abstract：:Pregnancy and the postpartum period confer an increased risk of stroke. The risk appears to be increased for all strokes during the puerperium and for hemorrhagic strokes during pregnancy. During pregnancy, physiologic systems are under increased stress to accommodate the growing fetus, which results in substantial he...

journal_title：Seminars in neurology

authors： Sells CM,Feske SK

更新日期：2017-12-01 00:00:00

abstract：:Multiple sclerosis (MS) affects more than 500,000 Americans, and it is commonly on the differential diagnosis associated with patient referrals to neurology offices. Diagnostically, there are several nuances to the established criteria. Understanding the usefulness of various tests and the potential diagnoses that can...

journal_title：Seminars in neurology

authors： Frohman EM,Greenberg BM

更新日期：2010-02-01 00:00:00

abstract：:Deficiencies in reading and writing appear to be major and lasting handicaps for learning-disabled college students. However, gains have been made in program modifications for learning-disabled students in many higher education institutions. Many adults with learning disabilities find that their handicap makes it diff...

journal_title：Seminars in neurology

authors： Gottesman RL

更新日期：1991-03-01 00:00:00

abstract：:Both general neurologists and neurologists with a broad spectrum of subspecialty interests are often asked to evaluate patients with disorders of the spinal cord. Over the past decade, there have been significant advances in our understanding of a wide spectrum of immune-mediated, infectious, metabolic, hereditary, pa...

journal_title：Seminars in neurology

authors： Kumar N

更新日期：2010-02-01 00:00:00

abstract：:Clinical guidelines for the determination of brain death in children were first published in 1987. These guidelines were revised in 2011 under the auspices of the Society of Critical Care Medicine, the American Academy of Pediatrics, and the Child Neurology Society, and provide the minimum standards that must be satis...

journal_title：Seminars in neurology

authors： Mathur M,Ashwal S

更新日期：2015-04-01 00:00:00

abstract：:The field of neurocritical care has evolved tremendously in recent years, a development explained vastly by the advent of neurophysiological monitoring. From basic intracranial pressure measurements to brain tissue oxygenation, microdialysis, cerebral blood flow (CBF), and surface and intracortical electroencephalogra...

journal_title：Seminars in neurology

authors： Francoeur CL,Pain M,Mayer SA

更新日期：2016-12-01 00:00:00

abstract：:Neuroimaging is commonly utilized in the evaluation of post-cardiac arrest patients, providing a unique ability to visualize and quantify structural brain injury that can complement clinical and electrophysiologic data. Despite its lack of validation, we would advocate that neuroimaging is a valuable prognostication t...

journal_title：Seminars in neurology

authors： Greer DM,Wu O

更新日期：2017-02-01 00:00:00

abstract：:Carotid endarterectomy is an established surgical procedure to prevent stroke. The indications, preoperative evaluation, surgical timing, technical details, complications, and special circumstances for the use of this operation are reviewed. Future developments in the surgical reconstruction of the extracranial caroti...

journal_title：Seminars in neurology

authors： Pritz MB

更新日期：1998-01-01 00:00:00

abstract：:Dizziness is a common chief complaint with an extensive differential diagnosis that includes both benign and serious conditions. Physicians must distinguish the majority of patients who suffer from self-limiting conditions from those with serious illnesses that require acute treatment. The preferred approach to the di...

journal_title：Seminars in neurology

authors： Gurley KL,Edlow JA

更新日期：2019-02-01 00:00:00

abstract：:Improved disease control is critical for enhancing the lives of those living with multiple sclerosis. With specific immunologic targets, monoclonal antibody (mAb) treatments are highly effective options for relapsing forms of multiple sclerosis. The mechanism, efficacy, and current safety profiles are detailed for the...

journal_title：Seminars in neurology

authors： Singer BA

更新日期：2016-04-01 00:00:00

abstract：:Cognitive complaints are common in any adult neurology practice, and may present in a variety of ways other than classic "memory loss." In this article, the author reviews a simple approach to a symptom-based differential diagnosis, including recognition of impairment in several key cognitive domains as well as associ...

journal_title：Seminars in neurology

authors： Woodruff BK

更新日期：2011-02-01 00:00:00

abstract：:The management of severe brain injury requires a comprehensive approach in which imaging is an indispensable complement to the clinical and physiological information acquired at the bedside. Neuroimaging methods are routinely used in the diagnosis and prognosis of a broad spectrum of patients with acute neurological d...

journal_title：Seminars in neurology

authors： Stevens RD,Pustavoitau A,Chalela JA

更新日期：2008-11-01 00:00:00

abstract：:Neuroimmunologic and systemic rheumatic diseases are frequently accompanied by inflammation of the eye, ocular adnexa, and orbital tissues. An understanding of the diverse forms of ophthalmic pathology in these conditions aids the clinician in making appropriate preventative, diagnostic, therapeutic, and prognostic de...

journal_title：Seminars in neurology

authors： Vodopivec I,Lobo AM,Prasad S

更新日期：2014-09-01 00:00:00

abstract：:Metastatic plexopathy is often a disabling accompaniment of advanced systemic cancer and may involve any of the peripheral nerve plexuses. Brachial plexopathy most commonly occurs in carcinoma of the breast and lung; lumbosacral plexopathy is most common with colorectal and gynecologic tumors, sarcomas, and lymphomas....

journal_title：Seminars in neurology

authors： Jaeckle KA

更新日期：2004-12-01 00:00:00

abstract：:Establishing an open and honest physician-patient relationship is essential for the proper evaluation and management of headache disorders. Obtaining a complete headache and medical history is the most important part of the initial diagnostic evaluation. This history should include information about headache onset, pa...

journal_title：Seminars in neurology

authors： Marks DR,Rapoport AM

更新日期：1997-01-01 00:00:00

abstract：:A recent development in the evaluation of peripheral neuropathy patients has been the identification of autoantibodies directed against various peripheral nerve antigens. For some conditions, assay for the antibodies can be very helpful in confirming a diagnosis. In others, an antibody may be associated with clinical ...

journal_title：Seminars in neurology

authors： Kissel JT

更新日期：1998-01-01 00:00:00

abstract：:Diet may influence stroke risk via several mechanisms, but the optimal dietary habits for stroke prevention are not well established. We reviewed English-language MEDLINE publications from January 1979 through November 2004 for experimental, observational, and clinical studies of dietary factors (minerals, fats, chole...

journal_title：Seminars in neurology

authors： Ding EL,Mozaffarian D

更新日期：2006-02-01 00:00:00