Large-scale imaging of cortical dynamics during sensory perception and behavior.

abstract：:Bladder and erectile dysfunction are common urologic complications of diabetes and are associated with reduced parasympathetic autonomic control. To determine whether disruption of ganglionic neurotransmission contributes to the loss of function, we investigated synaptic transmission at parasympathetic, major pelvic g...

journal_title：Journal of neurophysiology

authors： Tompkins JD,Vizzard MA,Parsons RL

更新日期：2013-02-01 00:00:00

abstract：:1. The response properties of 39 periodontal ligament mechanoreceptors (PDLMs) and 12 intradental mechanoreceptors (IMs) related to the intact mandibular canine tooth were isolated by extracellular recording methods from the ipsilateral trigeminal semilunar ganglion. 2. The stimulus threshold and response magnitude of...

journal_title：Journal of neurophysiology

authors： Dong WK,Shiwaku T,Kawakami Y,Chudler EH

更新日期：1993-05-01 00:00:00

abstract：:1. Spontaneous synaptic activity in networks formed by dissociated neurons from embryonic rat midbrain was analyzed in tight seal whole cell recordings. 2. Application of furosemide (0.5 mM) to the cell and its surrounding area increased the frequency of spontaneous synaptic currents. Incubation of the culture with fu...

journal_title：Journal of neurophysiology

authors： Jarolimek W,Brunner H,Lewen A,Misgeld U

更新日期：1996-06-01 00:00:00

abstract：:1. Whole cell patch-clamp recordings were made of low-voltage-activated (LVA) calcium (Ca2+) currents using 2 mM barium (Ba2+) as charge carrier. Acutely dissociated neurons from medial septum (MS) and the nucleus of the diagonal band (nDB) were examined in young adult (1-3 mo) and aged (24-26 mo) Fischer 344 rats. 2....

journal_title：Journal of neurophysiology

authors： Murchison D,Griffith WH

更新日期：1995-08-01 00:00:00

abstract：:1. The synthesis of information from different sensory modalities in the superior colliculus is an important precursor of attentive and orientation behavior. 2. This integration of multisensory information is critically dependent on inputs from a small area of association cortex, the anterior ectosylvian sulcus. Remov...

journal_title：Journal of neurophysiology

authors： Wallace MT,Stein BE

更新日期：1994-01-01 00:00:00

abstract：:Spinal neurons undergo large cyclic membrane potential oscillations during fictive locomotion in lamprey. It was investigated whether these oscillations were due only to synaptically driven excitatory and inhibitory potentials or if voltage-dependent inward conductances also contribute to the depolarizing phase by usi...

journal_title：Journal of neurophysiology

authors： Hu GY,Biró Z,Hill RH,Grillner S

更新日期：2002-06-01 00:00:00

abstract：:1. Neuron-specific expression of alternately spliced exons of the gene encoding the Phe-Met-Arg-Phe-NH2 (FMRFamide) family of neuropeptides and the role of encoded peptides in synaptic transmission were examined in an identified cardiorespiratory interneuron, the visceral white interneuron (VWI), in the snail Lymnaea....

journal_title：Journal of neurophysiology

authors： Skingsley DR,Bright K,Santama N,van Minnen J,Brierley MJ,Burke JF,Benjamin PR

更新日期：1993-03-01 00:00:00

abstract：:Neurons in both the lateral intraparietal area (LIP) of the monkey parietal cortex and the intermediate layers of the superior colliculus (SC) are activated well in advance of the initiation of saccadic eye movements. To determine whether there is a progression in the covert processing for saccades from area LIP to SC...

journal_title：Journal of neurophysiology

authors： Paré M,Wurtz RH

更新日期：2001-06-01 00:00:00

abstract：:The aim of this study was to examine whether subjects who have learned a skilled locomotor task can transfer the acquired performance to conditions involving either a change in the external coordinates or in the sensory input from one leg. Subjects were trained to step over an obstacle with minimal foot clearance with...

journal_title：Journal of neurophysiology

authors： Lam T,Dietz V

更新日期：2004-10-01 00:00:00

abstract：:Outward K+ currents were recorded using a whole cell patch-clamp configuration, from acutely dissociated adult rat cutaneous afferent dorsal root ganglion (DRG) neurons (L4 and L5) identified by retrograde labeling with Fluoro-gold. Recordings were obtained 16-24 h after dissociation from cells between 39 and 49 mm in...

journal_title：Journal of neurophysiology

authors： Everill B,Rizzo MA,Kocsis JD

更新日期：1998-04-01 00:00:00

abstract：:Ablation and single-unit studies in primates have shown that inferior temporal (IT) cortex is important for pattern discrimination. The first paper in this series suggested that single units in IT cortex of alert monkeys respond to a set of two-dimensional patterns with complex temporal modulation of their spike train...

journal_title：Journal of neurophysiology

authors： Optican LM,Richmond BJ

更新日期：1987-01-01 00:00:00

abstract：:The functional role of input from the primary motor cortex (M1) to primary somatosensory cortex (S1) is unclear; one key to understanding this pathway may lie in elucidating the cell-type specific microcircuits that connect S1 and M1. Recently, we discovered that a subset of pyramidal neurons in the infragranular laye...

journal_title：Journal of neurophysiology

authors： Kinnischtzke AK,Fanselow EE,Simons DJ

更新日期：2016-09-01 00:00:00

abstract：:Regional blood oxygenation in the cerebellum and posterior cerebral cortices was monitored with functional magnetic resonance imaging (fMRI) at four Tesla while 16 normal subjects performed three tasks with identical visual stimulation: fixation; attention focused upon either stimulus shape or color and sustained duri...

journal_title：Journal of neurophysiology

authors： Le TH,Pardo JV,Hu X

更新日期：1998-03-01 00:00:00

abstract：:The mitral cell primary dendrite plays an important role in transmitting distal olfactory nerve input from olfactory glomerulus to the soma-axon initial segment. To understand how dendritic active properties are involved in this transmission, we have combined dual soma and dendritic patch recordings with computational...

journal_title：Journal of neurophysiology

authors： Chen WR,Shen GY,Shepherd GM,Hines ML,Midtgaard J

更新日期：2002-11-01 00:00:00

abstract：:Flexible behavior requires the ability to delay a response until it is appropriate. This can be achieved by holding either a sensory or a motor representation online. Here we assess whether maintenance of sensory or motor material drives the motor system to different functional states, as indexed by alterations of cor...

journal_title：Journal of neurophysiology

authors： van den Hurk P,Mars RB,van Elswijk G,Hegeman J,Pasman JW,Bloem BR,Toni I

更新日期：2007-02-01 00:00:00

abstract：:Exercise, in the form of moderate daily treadmill training following nerve transection and repair leads to enhanced axon regeneration, but its effect on functional recovery is less well known. Female rats were exercised by walking continuously, at a slow speed (10 m/min), for 1 h/day on a level treadmill, beginning 3 ...

journal_title：Journal of neurophysiology

authors： Boeltz T,Ireland M,Mathis K,Nicolini J,Poplavski K,Rose SJ,Wilson E,English AW

更新日期：2013-06-01 00:00:00

abstract：:Subfornical organ (SFO) neurons exhibit heterogeneity in current expression and spiking behavior, where the two major spiking phenotypes appear as tonic and burst firing. Insight into the mechanisms behind this heterogeneity is critical for understanding how the SFO, a sensory circumventricular organ, integrates and s...

journal_title：Journal of neurophysiology

authors： Medlock L,Shute L,Fry M,Standage D,Ferguson AV

更新日期：2018-11-01 00:00:00

abstract：:Mesencephalic trigeminal (M-V) neurons are primary somatosensory neurons with somata located within the CNS, instead of in peripheral sensory ganglia. In amphibians, these unipolar cells are found within the optic tectum and have a single axon that runs along the mandibular branch of the trigeminal nerve. The axon has...

journal_title：Journal of neurophysiology

authors： Pratt KG,Aizenman CD

更新日期：2009-07-01 00:00:00

abstract：:1. Voltage-dependent K+ currents were studied in normal rat anterior pituitary cells using the patch-clamp technique. To obtain cultures enriched for lactotrophs, density gradient centrifugation was performed on pituitary cells isolated from lactating rats. 2. Depolarizations to about -30 mV from a holding potential o...

journal_title：Journal of neurophysiology

authors： Herrington J,Lingle CJ

更新日期：1994-08-01 00:00:00

abstract：:The centre médian-parafascicular (CM-Pf) complex is located at the posterior intralaminar nuclei of the thalamus and forms part of the nonspecific thalamocortical projection system and the internal circuit of the basal ganglia. However, the functional roles of this complex remain to be fully elucidated. Here we have e...

journal_title：Journal of neurophysiology

authors： Minamimoto T,Kimura M

更新日期：2002-06-01 00:00:00

abstract：:Histamine is a known secretagogue in adrenal chromaffin cells. Activation of G-protein linked H(1) receptors stimulates phospholipase C, which generates inositol trisphosphate leading to release of intracellular calcium stores and stimulation of calcium influx through store operated and other channels. This calcium le...

journal_title：Journal of neurophysiology

authors： Currie KP,Fox AP

更新日期：2000-03-01 00:00:00

abstract：:1. The propagation of antidromically activated action potentials in CA1 pyramidal neurons was examined with intrasomatic and intradendritic electrical recording and optical measurements using the fluorescent calcium indicator Calcium Green-1. 2. In somatic recordings, trains of 40 action potentials, activated at rates...

journal_title：Journal of neurophysiology

authors： Callaway JC,Ross WN

更新日期：1995-10-01 00:00:00

abstract：:Speech stimuli give rise to neural activity in the listener that can be observed as waveforms using magnetoencephalography. Although waveforms vary greatly from trial to trial due to activity unrelated to the stimulus, it has been demonstrated that spoken sentences can be discriminated based on theta-band (3-7 Hz) pha...

journal_title：Journal of neurophysiology

authors： Howard MF,Poeppel D

更新日期：2010-11-01 00:00:00

abstract：:This study investigated how the ability to extend the fingers and thumb recovers early after stroke and how the ability to extend all of the digits affects grasping performance. We studied 24 hemiparetic patients at 3 and 13 wk post stroke. At each visit, we tested the subjects' ability to actively extend all five dig...

journal_title：Journal of neurophysiology

authors： Lang CE,DeJong SL,Beebe JA

更新日期：2009-07-01 00:00:00

abstract：:1. Adult rats and rats with a postnatal age of 3-29 days (PN 3-29) were used for the preparation of in vitro slices of the frontal neocortex. Epileptiform activity was induced by bath application of the gamma-aminobutyric acid-A (GABAA) receptor antagonists bicuculline or picrotoxin. 2. The voltage-sensitive dye RH 41...

journal_title：Journal of neurophysiology

authors： Sutor B,Hablitz JJ,Rucker F,ten Bruggencate G

更新日期：1994-10-01 00:00:00

abstract：:Substance P (SP) is an undecapeptide that is co-localized with conventional transmitters in the nucleus accumbens (NAc). Its neurochemical and behavioral effects resemble those of cocaine and amphetamine. How SP accomplishes these effects is not known, partly because its cellular and synaptic effects are not well char...

journal_title：Journal of neurophysiology

authors： Kombian SB,Ananthalakshmi KV,Parvathy SS,Matowe WC

更新日期：2003-02-01 00:00:00

abstract：:The effects of neuronal density on morphological and functional attributes of the evolving networks were studied in cultured dissociated hippocampal neurons. Plating at different densities affected connectivity among the neurons, such that sparse networks exhibited stronger synaptic connections between pairs of record...

journal_title：Journal of neurophysiology

authors： Ivenshitz M,Segal M

更新日期：2010-08-01 00:00:00

abstract：:A plaid pattern is formed when two sinusoidal gratings of different orientations are added together. Previous work has shown that V1 neurons selectively encode the direction and orientation of the component gratings in a moving plaid but not the direction of the plaid itself (Movshon et al. 1985). We recorded the resp...

journal_title：Journal of neurophysiology

authors： Tinsley CJ,Webb BS,Barraclough NE,Vincent CJ,Parker A,Derrington AM

更新日期：2003-08-01 00:00:00

abstract：:Effective connectivity between cortical areas decreases during slow wave sleep. This decline can be observed in the reduced interareal propagation of activity evoked either directly in cortex by transcranial magnetic stimulation (TMS) or by sensory stimulation. We present here a large-scale model of the thalamocortica...

journal_title：Journal of neurophysiology

authors： Esser SK,Hill S,Tononi G

更新日期：2009-10-01 00:00:00

abstract：:Accurate temporal coding of low-frequency tones by spikes that are locked to a particular phase of the sine wave (phase-locking), occurs among certain groups of neurons at various processing levels in the brain. Phase-locked responses have previously been studied in the inferior colliculus and neocortex of the guinea ...

journal_title：Journal of neurophysiology

authors： Wallace MN,Anderson LA,Palmer AR

更新日期：2007-10-01 00:00:00