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Cloning, nucleotide sequence and characterization of a New Zealand rabbit metallothionein-I gene.

Abstract：

:We have isolated a rabbit metallothionein-I gene from a lambda gt10 library. The coding sequence of this gene is interrupted by two introns occurring at amino acid positions 9 1/3 and 30 1/3. Comparison of the promoter sequence of this gene with the promoters of other metallothionein genes identified a number of oligonucleotide sequences which are recognized by trans-acting proteins involved in the regulation of these genes by heavy metals, glucocorticoids and alpha interferon.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Tam YC,Chopra A,Hassan M,Thirion JP

doi

10.1016/s0006-291x(88)81210-5

subject

Has Abstract

pub_date

1988-05-31 00:00:00

pages

209-16

issue

1

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(88)81210-5

journal_volume

153

pub_type

杂志文章

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