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Epinephrine-activation of heparin-nonreleasable lipoprotein lipase in 3 skeletal muscle fiber types of the rat.

Abstract：

:Epinephrine was used to activate the heparin non-releasable lipoprotein lipase (LPL) in the 3 skeletal muscle fiber types of the perfused rat hindlimb. Following a 9 min washout of the capillary-bound lipoprotein lipase, the hindquarter of the rat was perfused with a buffer containing 10 nM of epinephrine. Activity of the residual LPL in soleus, red vastus lateralis, and white vastus lateralis muscles increased 75%, 96%, and 102% respectively, following epinephrine perfusion. These results suggest that skeletal muscle LPL is under hormonal control possibly through protein phosphorylation by cyclic AMP dependent protein kinase.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Miller WC,Gorski J,Oscai LB,Palmer WK

doi

10.1016/0006-291x(89)91504-0

subject

Has Abstract

pub_date

1989-10-31 00:00:00

pages

615-9

issue

2

eissn

0006-291X

issn

1090-2104

pii

0006-291X(89)91504-0

journal_volume

164

pub_type

杂志文章

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