Upregulation of myosin heavy chain MHClalpha in rat muscles after unweighting and clenbuterol treatment.

abstract：:ARD1 protein is a mammalian gene product homologous to a yeast Ard1p (Arrest defective 1 protein) acetyltransferase. Although two alternative splicing products of ARD1, ARD1(235) and ARD1(225), were reported in mouse, only ARD1(235) orthologue was reported in humans. Here we show that ARD1(225) is not expressed in hum...

journal_title：Biochemical and biophysical research communications

authors： Chun KH,Cho SJ,Choi JS,Kim SH,Kim KW,Lee SK

更新日期：2007-02-02 00:00:00

abstract：:Recombinant human insulin-like growth factor binding protein 3 (hIGFBP-3) stably expressed in chinese hamster ovary cells (CHO cells) has been purified to homogeneity from serum-free culture media. The purified protein migrates as a doublet (45/43 kDa) upon SDS-PAGE. The purified recombinant hIGFBP-3 is fully active a...

journal_title：Biochemical and biophysical research communications

authors： Tressel TJ,Tatsuno GP,Spratt K,Sommer A

更新日期：1991-07-31 00:00:00

abstract：:Wound healing in mammals can take several weeks to months and the process is always accompanied by scar formation. Wound healing mechanisms that mimic regeneration are not found in most mature mammalian tissues. However, the MRL/MPJ (MRL) mouse has the unique capacity to regenerate ear hole wound completely in less th...

journal_title：Biochemical and biophysical research communications

authors： Masinde G,Li X,Baylink DJ,Nguyen B,Mohan S

更新日期：2005-04-29 00:00:00

abstract：:Hepatocyte Growth Factor (HGF) was originally identified as hepatotrophic factor for liver regeneration. More recently, HGF was revealed to stimulate proliferation of various epithelial cells. At present study, we have investigated the mitogenic effect of HGF on gastric epithelial cells in the primary culture system. ...

journal_title：Biochemical and biophysical research communications

authors： Takahashi M,Ota S,Terano A,Yoshiura K,Matsumura M,Niwa Y,Kawabe T,Nakamura T,Omata M

更新日期：1993-03-15 00:00:00

abstract：:Chronic kidney disease (CKD) has recently emerged as a major risk factor for cardiovascular pathology. CKD patients display accelerated atherosclerotic process, leading to circulatory complications. However, it is currently not clear how uremic conditions accelerate atherosclerosis. Apoptosis is an important homeostat...

journal_title：Biochemical and biophysical research communications

authors： Trécherel E,Godin C,Louandre C,Benchitrit J,Poirot S,Mazière JC,Massy ZA,Galmiche A

更新日期：2012-01-06 00:00:00

abstract：:A cDNA clone for human transferrin was identified from a human liver cDNA library by pre-screening with different ss-cDNA probes against length-fractionated liver mRNAs, positive hybridization-selection and nucleotide sequence analysis. The insert was of 1 kb, encoding human transferrin from aminoacid 403 through the ...

journal_title：Biochemical and biophysical research communications

authors： Uzan G,Frain M,Park I,Besmond C,Maessen G,Trépat JS,Zakin MM,Kahn A

更新日期：1984-02-29 00:00:00

abstract：:Neurosteroids are endogenously derived compounds, mediating rapid effects in the central nervous system. They participate in vital processes, including memory and learning, neuroplasticity, and neuroprotection in Alzheimer's disease. However, the mechanisms behind those effects remain to be elucidated. The neurosteroi...

journal_title：Biochemical and biophysical research communications

authors： Elfverson M,Linde AM,Le Grevès P,Zhou Q,Nyberg F,Johansson T

更新日期：2008-07-25 00:00:00

abstract：:The aim of this study was to illustrate the further process of 24p3 protein after association with epididymal spermatozoa. We have previously identified a caput-initiated 24p3 protein, which interacts with the spermatozoa surface in vitro. In the present study, we investigate another role of the 24p3 protein with sper...

journal_title：Biochemical and biophysical research communications

authors： Elangovan N,Lee YC,Tzeng WF,Chu ST

更新日期：2004-07-09 00:00:00

abstract：:When TT virus (TTV) DNA was quantitated in whole blood and plasma aliquots from 27 viremic individuals by real-time detection PCR that can detect essentially all TTV genotypes, the TTV load was 6.9 +/- 3.5 (mean +/- standard deviation)-fold higher in the whole blood than in the plasma samples [P < 0.002 (paired t test...

journal_title：Biochemical and biophysical research communications

authors： Takahashi M,Asabe S,Gotanda Y,Kishimoto J,Tsuda F,Okamoto H

更新日期：2002-01-11 00:00:00

abstract：:Considering the dynamic nature of CYPs, methods that reveal information about substrate and enzyme dynamics are necessary to generate predictive models. To compare substrate dynamics in CYP2E1 and CYP2A6, intramolecular isotope effect experiments were conducted, using deuterium labeled substrates: o-xylene, m-xylene, ...

journal_title：Biochemical and biophysical research communications

authors： Harrelson JP,Henne KR,Alonso DO,Nelson SD

更新日期：2007-01-26 00:00:00

abstract：:Max binding protein (MNT) is a member of the Myc/Max/Mad network that plays a role in cell proliferation, differentiation and apoptosis. We previously observed that MNT was differentially expressed in hepatocellular carcinoma (HCC) and interacted with Nck1 by 2-DE. Nck family adaptor proteins function to couple tyrosi...

journal_title：Biochemical and biophysical research communications

authors： Wu J,Zhou Q,Wang Y,Zhou X,Li J

更新日期：2012-02-03 00:00:00

abstract：:We examined the expression of a Caenorhabditis elegans (C. elegans) elav-like gene, which we designated elr-1. The elr-1 gene encodes a predicted 456-amino-acid protein containing three putative RNA-binding domains and belongs to the ELAV family, which is functionally involved in neuronal differentiation. Northern blo...

journal_title：Biochemical and biophysical research communications

authors： Fujita M,Kawano T,Ohta A,Sakamoto H

更新日期：1999-07-14 00:00:00

abstract：:Glycogen synthase kinase-3beta (GSK3beta) is recognized as one of major kinases to phosphorylate tau in Alzheimer's disease (AD), thus lots of AD drug discoveries target GSK3beta. However, the inactive form of GSK3beta which is phosphorylated at serine-9 is increased in AD brains. This is also inconsistent with phosph...

journal_title：Biochemical and biophysical research communications

authors： Lim YW,Yoon SY,Choi JE,Kim SM,Lee HS,Choe H,Lee SC,Kim DH

更新日期：2010-04-30 00:00:00

abstract：:SHPS-1 (SHP substrate-1) is a glycosylated receptor-like protein with three immunoglobulin-like domains in its extracellular region and four YXX(L/V/I) motifs, potential tyrosine phosphorylation and SRC homology 2 (SH2) domain binding sites, in its cytoplasmic region. Various mitogens and cell adhesion induce tyrosine...

journal_title：Biochemical and biophysical research communications

authors： Yamao T,Matozaki T,Amano K,Matsuda Y,Takahashi N,Ochi F,Fujioka Y,Kasuga M

更新日期：1997-02-03 00:00:00

abstract：:To characterize mesenchymal stem cells (MSC), we compared gene expression profiles in human bone marrow MSC (11 lines) and human fibroblasts (4 lines) by RT-PCR and real time PCR. Messenger RNA levels of MHC-DR-alpha, MHC-DR-beta, MHC-DR-associated protein CD74, tissue factor pathway inhibitor-2, and neuroserpin were ...

journal_title：Biochemical and biophysical research communications

authors： Ishii M,Koike C,Igarashi A,Yamanaka K,Pan H,Higashi Y,Kawaguchi H,Sugiyama M,Kamata N,Iwata T,Matsubara T,Nakamura K,Kurihara H,Tsuji K,Kato Y

更新日期：2005-06-24 00:00:00

abstract：:Nitric oxide (NO) production is increased in the intestine and may contribute to intestinal injury in sepsis. However, the tissue expression of inducible NO synthase (iNOS) mRNA throughout the digestive tract and its relation with the mucosal damage after endotoxin challenge remain unknown. We therefore measured tissu...

journal_title：Biochemical and biophysical research communications

authors： Chen K,Inoue M,Okada A

更新日期：1996-07-25 00:00:00

abstract：:Tetrahymena p85 is localized to the presumptive division plane before division furrow formation; its molecular weight in SDS-polyacrylamide gel electrophoresis differs in wild-type and temperature-sensitive cell-division-arrest mutant cdaA1 cells. At the restrictive temperature, p85 localization and division furrow fo...

journal_title：Biochemical and biophysical research communications

authors： Gonda K,Nishibori K,Ohba H,Watanabe A,Numata O

更新日期：1999-10-14 00:00:00

abstract：:Gaf-1/Rip11 encoded by the clone KIAA0857 participates in endosomal recycling through the interaction with both gamma-SNAP, a member of the soluble NSF attachment protein family, and a small GTPase, Rab11. Gaf-1/Rip11 and other Rab11-interacting proteins constitute a novel protein family that is involved in the endocy...

journal_title：Biochemical and biophysical research communications

authors： Kawase K,Shibata M,Kawashima H,Hatsuzawa K,Nagahama M,Tagaya M,Tani K

更新日期：2003-04-18 00:00:00

abstract：:Receptor-mediated responses to prostaglandins E1 and E2 are shown by electrophysiological methods in follicle-enclosed oocytes of Xenopus laevis. In voltage-clamped oocytes, prostaglandins E1 and E2 elicited an outward hyperpolarizing current. This outward membrane current was caused by an increase in K+ conductance. ...

journal_title：Biochemical and biophysical research communications

authors： Mori K,Oka S,Tani A,Ito S,Watanabe Y

更新日期：1989-08-15 00:00:00

abstract：:Isocitrate dehydrogenase 1 (IDH1) mutations have been detected in gliomas and other tumors. Although IDH1 catalyzes the oxidative carboxylation of isocitrate to α-ketoglutarate (α-KG) in cytosol, mutated IDH1 proteins possess the ability to change α-KG into the oncometabolite D-2-hydroxyglutarate (D-2HG). Several mono...

journal_title：Biochemical and biophysical research communications

authors： Fujii Y,Ogasawara S,Oki H,Liu X,Kaneko MK,Takano S,Kato Y

更新日期：2015-10-30 00:00:00

abstract：:We established a sensitive and specific two-site enzyme immunoassay (EIA) for prolactin-releasing peptide (PrRP) using two region-specific monoclonal antibodies. We investigated the tissue distribution and the plasma concentration of immunoreactive (ir-) PrRP in rats using this assay. Ir-PrRP was widely distributed in...

journal_title：Biochemical and biophysical research communications

authors： Matsumoto H,Murakami Y,Horikoshi Y,Noguchi J,Habata Y,Kitada C,Hinuma S,Onda H,Fujino M

更新日期：1999-04-13 00:00:00

abstract：:In the presence of endothelin, there was a rapid increase in the 45Ca++ efflux from primary cultured rat vascular smooth muscle cells, both in physiological salt solution and in calcium free medium containing 2 mM EGTA. The 45Ca++ influx was not affected. The endothelin-induced, transient increase in cytosolic calcium...

journal_title：Biochemical and biophysical research communications

authors： Miasiro N,Yamamoto H,Kanaide H,Nakamura M

更新日期：1988-10-14 00:00:00

abstract：:To search autoantigens in autoimmune pancreatitis (AIP), we have screened the human pancreas cDNA library with a patient's serum and obtained 10 positive clones. Seven out of 10 clones were amylase alpha-2A, the autoantibody to which was specifically detected in sera from patients with AIP and fulminant type 1 diabete...

journal_title：Biochemical and biophysical research communications

authors： Takizawa S,Endo T,Wanjia X,Tanaka S,Takahashi M,Kobayashi T

更新日期：2009-08-14 00:00:00

abstract：:Various tumor cells express interleukin 7 (IL-7) and IL-7 variants. IL-7 has been confirmed to stimulate solid tumor cell proliferation. However, the effect of IL-7 variants on tumor cell proliferation remains unclear. In this study, we evaluated the role of IL-7δ5 (an IL-7 variant lacking exon 5) on proliferation and...

journal_title：Biochemical and biophysical research communications

authors： Pan D,Liu B,Jin X,Zhu J

更新日期：2012-06-15 00:00:00

abstract：:A bovine brain calmodulin-dependent protein kinase undergoes autophosphorylation with a maximal incorporation of 10 mol phosphate per mol enzyme. The autophosphorylated enzyme is fully active, independent of Ca2+ and calmodulin. Although the autophosphorylation reaction depends on Ca2+ and calmodulin, it can be render...

journal_title：Biochemical and biophysical research communications

authors： Zhang GY,Wang JH,Sharma RK

更新日期：1993-03-15 00:00:00

abstract：:Information about histone sequences and histone gene organization from invertebrate chordates is completely lacking. A genomic clone containing linked H3 and H4 histone genes from the urochordate Styela plicata was analyzed. The nucleotide sequence indicates that the two genes are transcribed in opposite directions an...

journal_title：Biochemical and biophysical research communications

authors： Ishaq AI,Rizvi SB,Wells DE,Tomlinson CR

更新日期：1993-07-30 00:00:00

abstract：:Myocardial stunning (temporary post-ischaemic contractile dysfunction) may be caused by oxidative stress and/or impaired myocyte calcium homeostasis. Regional myocardial stunning was induced in open-chest pigs (segment shortening reduced to 68.3+/-4.7% of baseline) by repetitive brief circumflex coronary occlusion (I/...

journal_title：Biochemical and biophysical research communications

authors： Kumar S,Hall RJ,Mani AR,Moore KP,Camici PG,Rimoldi OE,Williams AJ,Macleod KT

更新日期：2009-09-11 00:00:00

abstract：:A two fold stimulation in the incorporation of [3H-methyl] groups from [3H-methyl] methionine into phospholipids was seen in intact pancreatic islets within six minutes of exposure to a glucose concentration that stimulates insulin release. Nonstimulatory sugars, L-glucose and D-galactose, as well as dibutyryl cAMP, d...

journal_title：Biochemical and biophysical research communications

authors： Kowluru A,Rana RS,MacDonald MJ

更新日期：1984-07-31 00:00:00

abstract：:The effect of calcitonin gene-related peptide(CGRP) on the release of atrial natriuretic peptide(ANP) was studied in spontaneously beating, isolated rat atria. CGRP stimulated the ANP release in a dose-dependent manner. When the atria were incubated with a combination of phentolamine, propranolol, and atropine, these ...

journal_title：Biochemical and biophysical research communications

authors： Yamamoto A,Kimura S,Hasui K,Fujisawa Y,Tamaki T,Fukui K,Iwao H,Abe Y

更新日期：1988-09-30 00:00:00

abstract：:CREB3 (Luman) is a family member of ER resident transcription factors, which are cleaved upon the induction of ER stress. Their N-terminal fragments shuttle into the nucleus where they regulate the transcription of target genes. Here, we found that human CREB3 is phosphorylated within its transcription activation doma...

journal_title：Biochemical and biophysical research communications

authors： Schmitt BM,Ampofo E,Stumpf H,Montenarh M,Götz C

更新日期：2020-03-12 00:00:00