Abstract:
BACKGROUND:Cigarette smoke and asbestos are recognized causes of lung carcinoma and together promote carcinogenesis. Adenocarcinoma is currently the most common cause of lung cancer in the USA and it has been linked to both smoking and asbestos exposure. Mutations in the epidermal growth factor gene receptor (EGFR) occur predominantly in non-smokers with adenocarcinoma. Methods Mutations in the EGFR gene were investigated using next-generation sequencing. RESULTS:We report the presence of EGFR exon point mutations in the pulmonary adenocarcinomas of three never-smokers occupationally exposed to asbestos. CONCLUSION:The role of asbestos as a possible cause of EGFR mutagenesis requires further investigation. Am. J. Ind. Med. 60:306-309, 2017. © 2017 Wiley Periodicals, Inc.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Kradin RL,Iafrate J,Christiani DCdoi
10.1002/ajim.22691subject
Has Abstractpub_date
2017-03-01 00:00:00pages
306-309issue
3eissn
0271-3586issn
1097-0274journal_volume
60pub_type
杂志文章abstract:BACKGROUND:The need to expand the use of evaluation to learn how education programs contribute to workers' occupational safety and health is well documented. Similarly recognized is the need to expand workers' involvement as primary stakeholders in program evaluation. METHODS:Articles for this review were identified t...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/1097-0274(200011)38:5<584::aid-ajim11>3.0.
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:Although work-site obesity prevention programs have been widely promoted, they have a high rate of attrition and participants find it very difficult to maintain the decreased weight. It is necessary to develop effective work-site programs that match the type of intervention to the participants and offer the ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10059
更新日期:2002-04-01 00:00:00
abstract::The National Research Council's report "Protecting Youth at Work" addresses the health and safety consequences of work by youth in the United States. The report finds that a higher proportion of U.S. youth work than in any other developed nation and that as much as 80% of youth will have worked during their high schoo...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199911)36:5<579::aid-ajim1
更新日期:1999-11-01 00:00:00
abstract::Pathologists eligible for inclusion in the study were identified from the membership lists of the Royal College of Pathologists from 1974 to 1987, establishing a population of 4,512 members. Overall mortality was lower among the study group compared with the general population of England and Wales, although there were...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700200108
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:This study updates information on mortality and cancer morbidity in a cohort of Norwegian talc workers. METHODS:Follow-up was extended with 24 years, covering 1953-2011. Comparisons were made with the general population and between subgroups within the cohort. RESULTS:Standardized mortality ratio for non-m...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22749
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Fish processing is a common economic activity in Southern Africa. The aim of this study was to determine the prevalence and host determinants of allergic symptoms, allergic sensitization, bronchial hyper-responsiveness and asthma among workers processing saltwater fish. METHODS:A cross-sectional study was c...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20635
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Between 1987 and 1992, the Finnish Institute of Occupational Health (FIOH) initiated and implemented the Asbestos Program that aimed at reducing asbestos-related risks. It was a cooperative effort between government authorities, labor market organizations, and health care and labor protection personnel. MET...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20282
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:Self-employed business owners in Korea make up one-quarter of the working population, and half of those who are self-employed are in micro and small businesses. Compared to the significant research interest in business management and economics, to date, there has been little interest in the health of small b...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23023
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Migrant and seasonal farmworkers are at risk for occupational illnesses from pesticide exposure, and the effectiveness of pesticide safety regulations has not been evaluated. It is important to learn from farmworker safety experiences to develop effective measures to improve agricultural workplace safety. M...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1042
更新日期:2001-05-01 00:00:00
abstract:OBJECTIVE:To investigate the one-year prevalence of musculoskeletal symptoms and associated risk factors in a large sample of Chinese workers in various industrial settings. METHODS:A total of 5,338 (3,632 males and 1,706 females) workers from 13 companies participated in this study. Musculoskeletal symptoms in differ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.21037
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Nearly one of every three workers in the United States is low-income. Low-income populations have a lower life expectancy and greater rates of chronic diseases compared to those with higher incomes. Low- income workers face hazards in their workplaces as well as in their communities. Developing integrated pu...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22174
更新日期:2014-05-01 00:00:00
abstract::Investigators must often rely on self-reported work history information collected with questionnaires. However, little is known about the agreement between self-reported estimates of exposure and records kept by companies. As part of a cross-sectional medical study of structural fumigation workers, self-reported work ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199710)32:4<364::aid-ajim7
更新日期:1997-10-01 00:00:00
abstract:BACKGROUND:The occupational lung cancer risk in manufacturing and repair of shoes was studied by pooling of two major case-control studies from Germany. METHODS:Some 4184 incident hospital-based cases of primary lung cancer and 4253 population controls, matched for sex, age, and region of residence were intensively in...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(200006)37:6<575::aid-ajim1
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:Nickel (Ni) compounds have been classified as carcinogenic to humans. The aim of the study is to evaluate exposures to Ni at workplaces in Italy. METHODS:Data on Ni compounds were collected from an occupational exposure registry. Statistical analysis was carried out for exposure-related variables. The numbe...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22914
更新日期:2018-12-01 00:00:00
abstract::The most daunting problem in community-based studies of occupational cancer is retrospective exposure assessment. To avoid the error involved in using job title as the exposure variable or self-report of exposure, our team developed an approach based on expert judgment applied to job descriptions obtained by interview...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199703)31:3<280::aid-ajim3
更新日期:1997-03-01 00:00:00
abstract::Health care workers may be occupationally exposed to known and suspected teratogens including viruses, anesthetic gases, sterilants, mercury, and x-radiation. To assess the risk of congenital defects among offspring of health care workers, we analyzed parental occupational histories for 4,915 case babies with congenit...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700240103
更新日期:1993-07-01 00:00:00
abstract::An occupational injury surveillance project was conducted in 15 of Iowa's 99 counties. Trained abstractors reviewed the medical records of persons admitted for trauma to hospitals during 1983. Based on these chart reviews, subsequent mail-out questionnaires and phone contacts were made, and rate estimates for occupati...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700180213
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:The oncogene product EGF-receptor (EGF-R), the tumor suppressor gene product p53, and anti-p53 antibodies are detectable in serum of certain cancer patients. Increased levels of some of these products were reported in lung cancer patients after occupational asbestos exposure, after exposure to polycyclic aro...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,多中心研究
doi:10.1002/(sici)1097-0274(199912)36:6<602::aid-ajim2
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND:There are very few published studies evaluating the impact of safety and health training on injury outcomes in the construction industry. The aim of this study was to assess the impact of the training program on injury rates at a major railway construction project. METHODS:The population consisted of 2,795 ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20770
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:Many authorities are concerned about the rising use and the potential overuse of opioid pain medications. A study of opioid prevalence and dosage in Ohio's workers' compensation (WC) system was conducted, with comparisons made to opioid use in other WC and non-WC settings. METHODS:Systematic literature revi...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.21021
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Impairment of olfactory function in humans has been associated with occupational exposure to volatile chemicals. To investigate whether exposure to styrene was associated with olfactory impairment, olfactory function was examined in workers with a minimum of 4 years exposure to styrene in the reinforced-plas...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10102
更新日期:2003-07-01 00:00:00
abstract::This study examined mortality to December 31, 1989 in a cohort of 2,222 males employed between 1947 and 1975 at a transformer manufacturing plant in Canada, where there had been extensive use of transformer fluid, some containing polychlorinated biphenyls (PCBs). A combined cohort list of 2,222 names was independently...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700250310
更新日期:1994-03-01 00:00:00
abstract:BACKGROUND:Work-related injuries in commercial fishing are of concern internationally. To better identify the causes of injury, this study coded occupational injuries by working processes in commercial fishing for fresh market fish. METHODS:A classification system of the work processes was developed by participation i...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20163
更新日期:2005-06-01 00:00:00
abstract:OBJECTIVE:To compare fatal and hospitalized nonfatal work-related traumatic injuries by occupation and cause. METHODS:Fatal and hospitalized nonfatal injuries occurring from 1991-1995 were identified from Washington State workers' compensation claims data. Nonfatal injuries were classified as severe if they had at lea...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199908)36:2<317::aid-ajim1
更新日期:1999-08-01 00:00:00
abstract::In conjunction with industrial hygiene surveys, mutagenicity studies were performed for the airborne contaminants in three polyurethane manufacturing plants. Airborne particles were collected on glass-fiber filters with Hi-Vol pumps from different locations in each plant. Gases were collected in multiple-sorbent cartr...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700110410
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Use of worker's compensation (WC) as payer underestimates work-related (WR) injuries. We evaluated three methods to identify WR injuries: WC as payer, ICD-9-CM work-status codes E000.0/E000.1, and other ICD-9-CM external cause codes. METHODS:We identified injury-related emergency department visits from Nort...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22984
更新日期:2019-07-01 00:00:00
abstract::Quantitative evaluation of worker exposure to silica in nine Standard Industrial Classification (SIC) codes was conducted, using data derived from OSHA compliance inspections, in order to assess the silica exposure problem in the U.S. The nine SICs studied were those in which OSHA inspections were concentrated. They i...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700100403
更新日期:1986-01-01 00:00:00
abstract::In view of the increasing incidence of diseases such as gastritis and ulcers in workers exposed to noise, we assessed whether noise does in fact affect gastric secretion. Then, considering the conflicting findings published on the effects of noise on gastric secretion, we also investigated whether the response was rel...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700260310
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND:Studies comparing different forms of asbestos are rare, and limited by the failure to compare results with unexposed populations. We compare autoimmune responses among former workers and residents of the crocidolite mining and milling town of Wittenoom, Western Australia, with an unexposed population. METHO...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22863
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Occupational exposure to lead and solvents has declined steadily over the past 20 years, however, construction workers continue to be exposed to these neurotoxicants. The purpose of this study was to investigate the cognitive effects of chronic occupational exposure to lead and solvents. METHOD:Based on K-X...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10287
更新日期:2003-10-01 00:00:00