Respiratory pathogen panels in the hospital: good or unnecessary?

abstract：PURPOSE OF REVIEW:The aim of this review is to provide an update of nonantibiotic therapies for acute gastroenteritis (AGE), focusing on antiemetics and probiotics. RECENT FINDINGS:The mainstay of therapy for nonsevere AGE remains oral rehydration therapy (ORT). Recent randomized controlled trials and metaanalyses hav...

journal_title：Current opinion in infectious diseases

authors： Funk A,Schnadower D,Freedman SB

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:There is a history of inadequate treatments for cryptosporidiosis and a lack of understanding of the species that cause human disease. Against this background, we review the efficacy of antiparasitic agents, particularly nitazoxanide, which has led to increased treatment options, the potential for imm...

journal_title：Current opinion in infectious diseases

authors： Smith HV,Corcoran GD

更新日期：2004-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Enteric fever continues to be an important infection among populations in endemic countries and among travelers to these areas. This review aims to describe recent epidemiological trends and developments in diagnosis, treatment and prevention. RECENT FINDINGS:Data indicate that the burden of enteric ...

journal_title：Current opinion in infectious diseases

authors： Meltzer E,Schwartz E

更新日期：2010-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights progress made in the development of vaccines aimed at the stages of malaria parasites found in mosquitoes that block the transmission of malaria within a community. RECENT FINDINGS:Substantial progress has been made on the production and characterization of the leading candidat...

journal_title：Current opinion in infectious diseases

authors： Saul A

更新日期：2007-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The frequency and impact of viruses among intensive care unit (ICU) nonimmunocompromised patients remains controversial. This review analyzes their place as causal pathogens in ventilator-associated pneumonia, as well as their effects on ICU patients' outcomes. RECENT FINDINGS:Herpesviruses, namely h...

journal_title：Current opinion in infectious diseases

authors： Chiche L,Forel JM,Papazian L

更新日期：2011-04-01 00:00:00

abstract：:The sequence of the Treponema pallidum genome was completed in July 1998, yielding a wealth of new information regarding the enigmatic spirochete that causes syphilis and related treponematoses. By providing the sequences and predicted functions of over 1000 genes, the genome sequence will greatly facilitate research ...

journal_title：Current opinion in infectious diseases

authors： Norris SJ,Weinstock GM

更新日期：2000-02-01 00:00:00

abstract：:Therapeutic approaches in the practice of haematology/oncology are increasing in complexity. Agents such as the purine analogues and monoclonal antibodies may introduce a new spectrum of infection as a consequence of prolonged/profound lymphoid suppression. The use of high dose therapy with stem cells support is incre...

journal_title：Current opinion in infectious diseases

authors： Potter M

更新日期：1999-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Prion diseases such as Creutzfeldt-Jakob disease represent a unique infection control problem because prions exhibit an unusual resistance to conventional chemical and physical decontamination methods. This paper reviews the recent literature and provides recommendations for the prevention of nosocomi...

journal_title：Current opinion in infectious diseases

authors： Weber DJ,Rutala WA

更新日期：2002-08-01 00:00:00

abstract：PURPOSE OF REVIEW:HIV postexposure prophylaxis is often recommended following potential sexual exposure to HIV. Recent data address the effectiveness of postexposure prophylaxis and prevention counseling, cost-effectiveness, antiretroviral options, challenges with nonoccupational postexposure prophylaxis among adolesce...

journal_title：Current opinion in infectious diseases

authors： Roland ME

更新日期：2007-02-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Viruses are an increasingly recognized cause of community-acquired pneumonia (CAP), but their exact role in nosocomial pneumonia is still debated. This review focuses on the role of viruses as a cause of nosocomial pneumonia. RECENT FINDINGS:Respiratory viruses may be responsible for healthcare-a...

journal_title：Current opinion in infectious diseases

authors： Luyt CE,Bréchot N,Chastre J

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes past and ongoing efforts for using polyclonal and monoclonal antibodies for the treatment of influenza, and is focused on products that have entered clinical trials. RECENT FINDINGS:At least three polyclonal and eight monoclonal antibody products have been tested in clinical tr...

journal_title：Current opinion in infectious diseases

authors： Beigel JH

更新日期：2018-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Migrants living in high-income countries are disproportionately affected by HIV infection and frequently have characteristics associated with poor HIV clinical outcomes. HIV epidemiology among migrants is influenced by changes in migration patterns and variations in transmission risk behaviors. Here w...

journal_title：Current opinion in infectious diseases

authors： Ross J,Cunningham CO,Hanna DB

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To review risk-based pre-emptive treatment for adenovirus (ADV) based on quantitative PCR (qPCR) and to provide an update on clinical trials of brincidofovir (BCV) and ADV-specific cytotoxic T lymphocytes (ADV-CTLs). RECENT FINDINGS:ADV qPCR in various body compartments enables distinction of clinica...

journal_title：Current opinion in infectious diseases

authors： Lee YJ,Prockop SE,Papanicolaou GA

更新日期：2017-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The world's population is becoming increasing mobile. Each mobile population (e.g. immigrants, refugees, travelers) has certain characteristics that determine public health risk and infectious disease burden. Refugees present unique challenges to public health officials and infectious disease speciali...

journal_title：Current opinion in infectious diseases

authors： Stauffer WM,Weinberg M

更新日期：2009-10-01 00:00:00

abstract：:Although the association remains controversial, enteroviruses have been implicated in the aetiology of several chronic diseases in humans. Investigations in vitro lead to better understanding of virus-cell interactions, and improve our knowledge of the molecular factors that are involved in the establishment and maint...

journal_title：Current opinion in infectious diseases

authors： Frisk G

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Burkholderia mallei is a facultative intracellular pathogen that causes the highly contagious and often the fatal disease, glanders. With its high rate of infectivity via aerosol and recalcitrance toward antibiotics, this pathogen is considered a potential biological threat agent. This review focuses ...

journal_title：Current opinion in infectious diseases

authors： Saikh KU,Mott TM

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Climate change, deforestation, urbanization, and increased population mobility have made the risk of large outbreaks of yellow fever more likely than ever. Yellow fever vaccine production barely meets demands. In this review, we address the causes of the recent yellow fever outbreaks, why fractional d...

journal_title：Current opinion in infectious diseases

authors： Visser LG

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review identifies trends in the study of interactions between Staphylococcus aureus and humans. When nasal colonization is in the neutral state, infection clearly represents a state of host-pathogen disbalance. The features leading from apparent homeostatic colonization to pathogenesis are identi...

journal_title：Current opinion in infectious diseases

authors： van Belkum A

更新日期：2006-08-01 00:00:00

abstract：:Tuberculosis in childhood is an important cause of mortality worldwide. The disease is difficult to diagnose and the underlying immune mechanisms are poorly understood. Advances in the application of molecular genetic tools, as illustrated by the recent completion of the genome sequence of Mycobacterium tuberculosis, ...

journal_title：Current opinion in infectious diseases

authors： Kampmann B,Young D

更新日期：1998-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Antimicrobial resistance (AMR) is a threat to global health and new approaches to combating AMR are needed. Use of machine learning in addressing AMR is in its infancy but has made promising steps. We reviewed the current literature on the use of machine learning for studying bacterial AMR. RECENT FI...

journal_title：Current opinion in infectious diseases

authors： Macesic N,Polubriaginof F,Tatonetti NP

更新日期：2017-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The early treatment of invasive fungal infection is critical but is hampered by the non-specific nature of clinical and radiological signs and the insensitivity of current laboratory diagnostic methods. If mortality due to invasive fungal infection is to be reduced, new, preemptive therapeutic strateg...

journal_title：Current opinion in infectious diseases

authors： Jones BL,McLintock LA

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The issue of whether the outcome of bacteremic pneumococcal infections is improved with the use of combination antibiotic therapy versus monotherapy is still not resolved. This review highlights recent studies that have addressed this issue. RECENT FINDINGS:Some studies have indicated benefit of comb...

journal_title：Current opinion in infectious diseases

authors： Feldman C,Anderson R

更新日期：2009-04-01 00:00:00

abstract：PURPOSE OF REVIEW:There is a global need for well tolerated, effective, and affordable vaccines to prevent group A streptococcal infections and their most serious complications. The aim of this review is to highlight the recent progress in the identification of promising vaccine antigens and new approaches to vaccine d...

journal_title：Current opinion in infectious diseases

authors： Dale JB,Walker MJ

更新日期：2020-06-01 00:00:00

abstract：PURPOSE OF REVIEW:For decades, healthcare workers have been known to be at risk from acquiring a variety of bloodborne pathogen infections as a result of occupational exposure. Primary prevention of exposures, as recommended by universal precautions guidelines, remains the cornerstone of protecting healthcare workers. ...

journal_title：Current opinion in infectious diseases

authors： Beekmann SE,Henderson DK

更新日期：2005-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Colonization of the host epithelia by pathogenic Escherichia coli is influenced by the ability of the bacteria to interact with host surfaces. Because the initial step of an E. coli infection is to adhere, invade, and persist within host cells, some strategies used by intestinal and extraintestinal E....

journal_title：Current opinion in infectious diseases

authors： Kalita A,Hu J,Torres AG

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review addresses recent developments that relate to the pathogenesis of severe malaria and its treatment, and also highlights the increase in the global burden of malaria and provides a summary of clinical trials of malaria vaccines. RECENT FINDINGS:Malaria, one of the world's most important par...

journal_title：Current opinion in infectious diseases

authors： Maitland K,Bejon P,Newton CR

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The need for better drugs to treat patients with Chagas disease remains urgent. This review summarizes the advancements in drug development over the past 2 years. RECENT FINDINGS:Drug development efforts are almost exclusively occurring as preclinical research, although phase II studies for the antif...

journal_title：Current opinion in infectious diseases

authors： Buckner FS,Navabi N

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to provide an update on the public health impact of food-related illness in light of recent high-profile outbreaks and advances in the methodology to estimate illness burden. It includes mainly literature from high-income countries, as burden of illness estimations have b...

journal_title：Current opinion in infectious diseases

authors： O'Brien SJ

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The leishmaniases, caused by protozoan parasites of the genus Leishmania, are a significant health problem in many regions of the world. This review highlights the recent advances in the study of leishmaniasis related to parasite biology, disease pathogenesis, clinical evaluation and treatment, and pr...

journal_title：Current opinion in infectious diseases

authors： Melby PC

更新日期：2002-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The source, significance and optimal management of low-level viraemia during highly active antiretroviral therapy (HAART) are poorly defined. This review highlights recent observations that have implications for clinical practice. RECENT FINDINGS:The definition of low-level viraemia remains elusive. ...

journal_title：Current opinion in infectious diseases

authors： Doyle T,Geretti AM

更新日期：2012-02-01 00:00:00