Eruptive xanthomas in a child with the nephrotic syndrome.

abstract：:We report two cases of congenital curvilinear palpable hyperpigmentation on the posterior aspect of bilateral legs in male infants. These lesions appeared shortly after birth and mimicked child abuse with looped cord or postinflammatory hyperpigmentation. Histopathologic features showed lentiginous melanocytic hyperpl...

journal_title：Journal of the American Academy of Dermatology

authors： Zhu YI,Fitzpatrick JE,Weston WL

更新日期：2005-08-01 00:00:00

abstract：:Immunopathology continues to be important in diagnostic dermatopathology. Immunopathology is an invaluable tool for assessing the tissue of origin or direction of differentiation of cells. In some cases this can result in a more precise diagnosis. This article reviews the role of immunopathology in determining the bio...

journal_title：Journal of the American Academy of Dermatology

authors： Wallace ML,Smoller BR

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Rituximab has been increasingly used in autoimmune blistering dermatoses, mainly in pemphigus. However, only a few larger case series are available on this subject and information on the efficacy of retreatment with rituximab during relapses is lacking. OBJECTIVE:We sought to determine efficacy and adverse ...

journal_title：Journal of the American Academy of Dermatology

authors： Kasperkiewicz M,Shimanovich I,Ludwig RJ,Rose C,Zillikens D,Schmidt E

更新日期：2011-09-01 00:00:00

abstract：:The psychosocial impact of infection with human immunodeficiency virus (HIV) can be viewed from three perspectives: (1) the issues focused by acquired immunodeficiency syndrome (AIDS), (2) the persons affected, and (3) the emotions encountered. Among the many issues faced by AIDS patients, their families, and their ca...

journal_title：Journal of the American Academy of Dermatology

authors： Cline DJ

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Dermatitis herpetiformis (DH) is highly associated with celiac disease. Recently, tissue transglutaminase (tTG) was identified as the autoantigen of IgA antibodies in celiac disease. The prevalence of antibodies to tTG in DH patients is not known. OBJECTIVE:The purpose of this study was to determine whether...

journal_title：Journal of the American Academy of Dermatology

authors： Rose C,Dieterich W,Bröcker EB,Schuppan D,Zillikens D

更新日期：1999-12-01 00:00:00

abstract：:Pruritus is a common symptom in patients with hepatobiliary disease. Numerous treatments have been attempted. We review published therapeutic trials for hepatobiliary pruritus and utilize statistical analysis to evaluate treatment results. Randomized placebo-controlled studies show cholestyramine, rifampin, naloxone, ...

journal_title：Journal of the American Academy of Dermatology

authors： Connolly CS,Kantor GR,Menduke H

更新日期：1995-11-01 00:00:00

abstract：:The clinical, electron microscopic, and freeze-fracture features of the skin of a harlequin fetus are described. Ultrastructural findings included large, concentric lamellar bodies, focal absence of intercellular stratum corneum lipid, and an increase in the size of desmosomes and the number of tight junctions. Althou...

journal_title：Journal of the American Academy of Dermatology

authors： Fleck RM,Barnadas M,Schulz WW,Roberts LJ,Freeman RG

更新日期：1989-11-01 00:00:00

abstract：:We present the case of two patients with an unusual form of discoid lupus erythematosus that was confined almost exclusively to the palms and soles. In both patients this form of discoid lupus erythematosus did not respond to conventional therapies, which included topical steroids, intralesional steroids, prednisone, ...

journal_title：Journal of the American Academy of Dermatology

authors： Ashinoff R,Werth VP,Franks AG Jr

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Knowledge is limited regarding unknown primary Merkel cell carcinoma (UPMCC). OBJECTIVE:We sought to document the characteristics and behavior of UPMCC, and determine the most appropriate treatment. METHODS:A multicenter, retrospective, consecutive study reviewing patients given a diagnosis of UPMCC betwee...

journal_title：Journal of the American Academy of Dermatology

authors： Tarantola TI,Vallow LA,Halyard MY,Weenig RH,Warschaw KE,Weaver AL,Roenigk RK,Brewer JD,Otley CC

更新日期：2013-03-01 00:00:00

abstract：:Several infections contracted in utero result in similar physical and laboratory findings during the neonatal period; the TORCH syndrome encompasses such patients. Skin lesions are a frequent finding and the dermatologist may play an important role in the early evaluation of these infants. In this review we discuss et...

journal_title：Journal of the American Academy of Dermatology

authors： Fine JD,Arndt KA

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:Current treatments for vitiligo, a common pigmentary disorder affecting around 1% of the world's population, are largely unsatisfactory. OBJECTIVE:We sought to report a Cochrane review of all interventions for the treatment of vitiligo. METHODS:We systematically searched a range of databases for randomized...

journal_title：Journal of the American Academy of Dermatology

authors： Whitton ME,Ashcroft DM,González U

更新日期：2008-10-01 00:00:00

abstract：:A 46-year-old albino woman is described with a melanoma on the leg from which a punch biopsy specimen was inadvertently taken. In the reexcision specimen, two biopsy wounds were recognized that were filled with tumor. The initial level III lesion had to be subsequently reported as a deep level IV amelanotic melanoma w...

journal_title：Journal of the American Academy of Dermatology

authors： van der Esch EP,Rampen FH

更新日期：1985-11-01 00:00:00

abstract：:Calciphylaxis is a rare phenomenon of cutaneous necrosis that typically occurs in association with renal failure and has a poor prognosis. We report 5 new cases of calciphylaxis that illustrate the important clinical and histopathologic features of the disease. All patients had end-stage renal failure at the time that...

journal_title：Journal of the American Academy of Dermatology

authors： Oh DH,Eulau D,Tokugawa DA,McGuire JS,Kohler S

更新日期：1999-06-01 00:00:00

abstract：:The occurrence of Kaposi's sarcoma in young homosexual men is a recently reported condition. The same individuals are at risk for the development of Pneumocystis carinii pneumonia and other unusual infections. These associations suggest these persons are somehow immunocompromised. Evidence of current or prior cytomega...

journal_title：Journal of the American Academy of Dermatology

authors： Rasmussen EO,Cooper KD,Kang K,White CR Jr,Regan DH,Hanifin JM

更新日期：1982-05-01 00:00:00

abstract：:Malignant melanoma presenting as an inflammatory skin metastasis has been described but is an exceedingly rare phenomenon. We report an unusual case of a patient who developed right leg lesions that were initially thought to be infectious in origin. There was no resolution of these lesions with antibiotic therapy, and...

journal_title：Journal of the American Academy of Dermatology

authors： Cotton J,Armstrong DJ,Wedig R,Hood AF

更新日期：1998-11-01 00:00:00

abstract：:This study was conducted to further evaluate the safety and efficacy of 3% topical minoxidil in the treatment of extensive alopecia areata. Patients were assigned to one of two treatment regimens in a double-blind manner. One group applied 3% minoxidil to the scalp twice daily for 64 weeks; the other group applied pla...

journal_title：Journal of the American Academy of Dermatology

authors： Price VH

更新日期：1987-03-01 00:00:00

abstract：:Acute generalized exanthematous pustulosis is a severe cutaneous adverse reaction characterized by the rapid development of nonfollicular, sterile pustules on an erythematous base. It is attributed to drugs in the majority of cases. Antibiotics are the most common cause of acute generalized exanthematous pustulosis; h...

journal_title：Journal of the American Academy of Dermatology

authors： Szatkowski J,Schwartz RA

更新日期：2015-11-01 00:00:00

abstract：:Two families with anetoderma are described. Unlike previous reports of familial anetoderma, the disease process seemed to be limited to the skin, and there were no associated ocular, gastrointestinal, or orthopedic anomalies in the affected patients or in any other family members. Although infrequently reported, aneto...

journal_title：Journal of the American Academy of Dermatology

authors： Friedman SJ,Venencie PY,Bradley RR,Winkelmann RK

更新日期：1987-02-01 00:00:00

abstract：:Six months after the occurrence of pyoderma gangrenosum, subcorneal pustular dermatosis developed in a 60-year-old woman. The patient's serum was found to contain an IgA-lambda paraprotein. Although similar cases have been reported, this case is unique in that a distinct episode of pyoderma gangrenosum was followed by...

journal_title：Journal of the American Academy of Dermatology

authors： Kohl PK,Hartschuh W,Tilgen W,Frosch PJ

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Patients with rosacea have increased amounts of cathelicidin and protease activity but their usefulness as disease biomarkers is unclear. OBJECTIVE:We sought to evaluate the effect of doxycycline treatment on cathelicidin expression, protease activity, and clinical response in rosacea. METHODS:In all, 170 ...

journal_title：Journal of the American Academy of Dermatology

authors： Di Nardo A,Holmes AD,Muto Y,Huang EY,Preston N,Winkelman WJ,Gallo RL

更新日期：2016-06-01 00:00:00

abstract：:"Poikiloderma" is a morphologic and descriptive term referring to a combination of cutaneous atrophy, telangiectasia, and varied macular pigmentary changes that result in a mottled skin appearance. Its etiology includes both congenital and acquired causes. Many studies have reported different causes of acquired poikil...

journal_title：Journal of the American Academy of Dermatology

authors： Nofal A,Salah E

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Sarcoidosis and granuloma annulare (GA) are cutaneous granulomatous disorders that can be difficult to treat. There is evidence of underlying Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway activation in sarcoidosis, suggesting that JAK inhibition might be effective. OBJEC...

journal_title：Journal of the American Academy of Dermatology

authors： Damsky W,Thakral D,McGeary MK,Leventhal J,Galan A,King B

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:The use of cutaneous resurfacing lasers to treat rhytides is widely accepted. Several carbon dioxide lasers, many using fundamentally different technologies, are available. OBJECTIVE:The purpose of this study was to compare the results obtained and side effects after treating rhytides with 3 different carbo...

journal_title：Journal of the American Academy of Dermatology

authors： Gross EA,Rogers GS

更新日期：1998-10-01 00:00:00

abstract：:We describe a 33-year-old patient with a giant skin tumor on her right big toe. The tumor was characterized by unusual clinical manifestations including huge size and papillomatous surface. Chronic long-standing irritation as a result of aerobic exercise may have been involved in the development of giant fibrokeratoma...

journal_title：Journal of the American Academy of Dermatology

authors： Kakurai M,Yamada T,Kiyosawa T,Ohtsuki M,Nakagawa H

更新日期：2003-05-01 00:00:00

abstract：:Skin toxicities are the most common side effects associated with the epidermal growth factor receptor inhibitor erlotinib, occurring in most patients receiving the drug. Clinical trials evaluating erlotinib for the treatment of non-small cell lung cancer have reported a range of skin disorders, the most common being a...

journal_title：Journal of the American Academy of Dermatology

authors： Kiyohara Y,Yamazaki N,Kishi A

更新日期：2013-09-01 00:00:00

abstract：:Patients with basal cell carcinoma and solar keratoses were treated with etretinate. Substantial and prolonged clinical improvement was seen. All patients with solar keratoses showed a decrease in the mean area and number of lesions and eight patients demonstrated complete healing clinically. Two patients experienced ...

journal_title：Journal of the American Academy of Dermatology

authors： Hughes BR,Marks R,Pearse AD,Gaskell SA

更新日期：1988-03-01 00:00:00

abstract：:Ochronosis is an uncommon condition characterized by yellow-brown pigment deposits in the dermis. It occurs in exogenous and endogenous forms. We report a case of exogenous ochronosis in a Hispanic woman and discuss the different forms of this condition. We treated the lesions with Q-switched ruby laser. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kramer KE,Lopez A,Stefanato CM,Phillips TJ

更新日期：2000-05-01 00:00:00

abstract：:Euxyl K 400 is a preservative system for cosmetics and toiletries that contains phenoxyethanol and methyldibromoglutaronitrile in a 4:1 ratio. In The Netherlands, Italy, and Germany, the prevalence of allergy to Euxyl K 400 has risen in the past 4 years and is currently 2% to 4% in patients suspected of having contact...

journal_title：Journal of the American Academy of Dermatology

authors： De Groot AC,van Ginkel CJ,Weijland JW

更新日期：1996-11-01 00:00:00

abstract：:Five of seven patients with acquired immunodeficiency syndrome (AIDS) who had pruritus and a chronic, nonspecific-appearing skin eruption had increased antibody titers to antigens in the salivary glands of Aedes taeniorhynchus, a salt marsh mosquito common to South Florida. We hypothesize that the pruritus and skin le...

journal_title：Journal of the American Academy of Dermatology

authors： Penneys NS,Nayar JK,Bernstein H,Knight JW

更新日期：1989-08-01 00:00:00

abstract：:Pyoderma gangrenosum is a neutrophilic dermatosis that may be associated with myeloid malignancies. Less information is available about the association of pyoderma gangrenosum with lymphoid malignancies. We present, to our knowledge, the first case of pyoderma gangrenosum associated with biphenotypic acute leukemia wh...

journal_title：Journal of the American Academy of Dermatology

authors： Asai M,Aragane Y,Kawada A,Shimada T,Kanamaru A,Yamada H,Tezukam T

更新日期：2001-03-01 00:00:00