Usefulness of Modified Dindo-Clavien Scale to Evaluate the Correlation Between the Severity of Surgical Complications and Complications Related to the Renal and Pancreatic Grafts After Simultaneous Kidney and Pancreas Transplantation.

Abstract:

OBJECTIVE:Simultaneous pancreas and kidney transplantation (spktx) is the multiorgan transplantation. Thus various complications originated from transplanted organs and the complications that are not directly related to pancreatic or renal grafts could be developed at the same recipient. AIM:The aim of this study is to explore whether there is a correlation between the severity of complications originated from transplanted pancreas, transplanted kidney and general surgical complication developed at the same spktx recipient. METHODS:Complications which developed among 112 spktx recipients were divided into three groups: related to the pancreatic graft (PTXc), to the renal graft (KTXc) and the general surgical complication (GNc). Severity of postoperative complications using modified Dindo-Clavien scale recipients was evaluated for each group. The correlation of severity of coexisting complications from different complication groups was analyzed. RESULTS:There were 22 recipients who developed the coexistence of complication between different complication groups. Complication originated from two and three complication groups developed 15 (68.2%) and 7 (31.8%) patients, respectively. There was not found correlation of the complication severity between: KTXc and GNc group, GNc and PTXc group, KTXc and PTXc group. The correlation (r = 0.84) of complication severity in recipients who developed concurrently complication from transplanted kidney, transplanted pancreas and general surgery complication was found. CONCLUSION:The modified Dindo-Clavien scale is an useful methodology for the correlation description of complication severity in complex multiorgan transplantation such is spktx, especially when the complications originated from different, potentially independent from the pathophysiological point of view, sources.

journal_name

Transplant Proc

authors

Grochowiecki T,Madej K,Gałązka Z,Jakimowicz T,Jędrasik M,Świercz P,Łukawski K,Pączek L,Durlik M,Nazarewski S,Szmidt J

doi

10.1016/j.transproceed.2016.01.091

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

1677-80

issue

5

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(16)00356-0

journal_volume

48

pub_type

杂志文章
  • Liver ischemic preconditioning: a new strategy for the prevention of ischemia-reperfusion injury.

    abstract::Ischemic preconditioning renders the liver more tolerant to ischemia-reperfusion injury in warm and cold ischemia-reperfusion models. In general, the application of a 5 to 10-minute period of ischemia followed by 10 minutes of reperfusion confers early effective protection to the liver. Mechanisms responsible for this...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/s0041-1345(03)00571-2

    authors: Peralta C,Serafin A,Fernández-Zabalegui L,Wu ZY,Roselló-Catafau J

    更新日期:2003-08-01 00:00:00

  • The impact of experience of a transplantation center on the outcomes of orthotopic liver transplantation.

    abstract::The so-called learning factor has been disregarded for many years in analyzing the causes of surgical complications and post-operative mortality; it is also the case for OLT. In our center until April 2003, 209 OLT were performed in 196 patients. We evaluated the impact of experience of the transplantation team on the...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/s0041-1345(03)00834-0

    authors: Krawczyk M,Grzelak I,Zieniewicz K,Nyckowski P,Pawlak J,Michałowicz B,Patkowski W,Alsharabi A,Wróblewski T,Paluszkiewicz R,Małkowski P,Hevelke P,Pszenny C,Remiszewski P,Skwarek A,Smoter P,Grodzicki M,Kornasiewicz O,Kor

    更新日期:2003-09-01 00:00:00

  • Efficacy of subcutaneous epoetin-zeta on anemia in renal transplant recipients: a single-center experience.

    abstract:BACKGROUND:Persistent or "de novo" anemia (plasma hemoglobin<11 g/dL) may complicate the graft outcome in a significant number of renal transplant recipients. We describe a single-center experience with epoetin-zeta (EPO-Z), the biosimilar form for epoetin-alfa. METHODS:Twenty patients were included in the study, 10 i...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2014.07.027

    authors: Sabbatini M,Vitale S,Garofalo G,Torino M,Gallo R,Carrano R,Federico S

    更新日期:2014-09-01 00:00:00

  • Prognostic evaluation of the donor risk index among a prospective cohort of Italian patients undergoing liver transplantation.

    abstract:BACKGROUND/AIM:The definition of an extended criteria donor for orthotopic liver transplantation (OLT) remains controversial. The donor risk index (DRI) has become the main tool to define the marginality of hepatic grafts in the United States. The aim of this study was to prospectively evaluate the prognostic ability o...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2009.03.097

    authors: Vitale A,D'Amico F,Gringeri E,Valmasoni M,Pauletto A,Bonsignore P,Bassi D,D'Amico FE,Polacco M,Burra P,Russo F,Angeli P,Poci C,Feltracco P,Romano A,Cillo U

    更新日期:2009-05-01 00:00:00

  • External biliary fistula in orthotopic liver transplantation.

    abstract::During orthotopic liver transplantation (OLT), various situations may occur in which biliary reconstruction is neither technically feasible nor recommended. One bridge to a delayed anastomosis can be an external biliary fistula (EBF). This procedure allows the surgeon to execute hemostatic maneuvers, such as abdominal...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2009.03.026

    authors: Gilbo N,Mirabella S,Strignano P,Ricchiuti A,Lupo F,Giono I,Sanna C,Fop F,Salizzoni M

    更新日期:2009-05-01 00:00:00

  • Treatment of nonalbumin rats by transplantation of immortalized hepatocytes using artificial human chromosome.

    abstract::The shortage of organ donors has impeded the development of human hepatocyte transplantation. Immortalized hepatocytes, however, could provide an unlimited supply of transplantable cells. To determine whether immortalized hepatocytes could provide global metabolic support in end-stage liver disease, rat hepatocyte clo...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2008.10.023

    authors: Ito M,Ikeno M,Nagata H,Yamamoto T,Hiroguchi A,Fox IJ,Miyakawa S

    更新日期:2009-01-01 00:00:00

  • Early postoperative complications of pediatric liver transplantation: experience at one center.

    abstract::To evaluate the postoperative complications within the first month among 20 pediatric liver transplant recipients between April 1990 and March 2003 we retrospectively studied their medical charts to gather demographic data; primary diagnosis; operative duration; perioperative transfusions; time to extubation; length o...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2003.11.029

    authors: Araz C,Pirat A,Torgay A,Zeyneloglu P,Arslan G

    更新日期:2004-01-01 00:00:00

  • Antiviral therapy for hepatitis B after kidney transplantation.

    abstract::The clinical outcome of HBsAg-positive renal transplant recipients has been adversely affected by potentially fatal acute hepatitic exacerbations and chronic liver disease, in addition to the increased risk of hepatocellular carcinoma. The difficulty in predicting the evolution and severity of liver disease after kidn...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2004.07.062

    authors: Chan TM

    更新日期:2004-09-01 00:00:00

  • Comparison of Two Different Inhalation Anesthetics on Grafted Kidney Function in Patients Undergoing Renal Transplantation Surgery: Desflurane or Sevoflurane?

    abstract:BACKGROUND:Anesthetic management of patients during renal transplantation is vitally important for ensuring proper functioning of kidneys that have undergone ischemia-reperfusion damage. The goal of this prospective study was to compare the effects of 2 different inhalation agents (sevoflurane and desflurane) on grafte...

    journal_title:Transplantation proceedings

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.transproceed.2017.01.014

    authors: Karadeniz MS,Ciftci HS,Tefik T,Mammadov O,Yazıcı H,Nane I,Turkmen A,Oguz F,Tugrul KM

    更新日期:2017-04-01 00:00:00

  • Diagnostic performance of serum cystatin C and serum creatinine in the prediction of chronic kidney disease in renal transplant recipients.

    abstract:BACKGROUND:Chronic kidney disease (CKD) has adverse impacts on mortality and morbidity of renal transplant recipients. Serum cystatin C (sCysC) is a novel marker in predicting the CKD. We therefore compare sCysC and serum creatinine (sCr) with the aim of improving the detection of CKD in renal transplant recipients. M...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2010.09.150

    authors: Tsai JP,Wu SW,Hung TW,Kao WT,Hong CL,Lian JD,Chang HR

    更新日期:2010-12-01 00:00:00

  • Epidemiologic and Economic Aspects Related to Hemodialysis and Kidney Transplantation in Santa Catarina in the Period of 2012-2013.

    abstract:BACKGROUND:Chronic kidney disease (CKD) is a worldwide public health problem and is expressed by increasing amounts of patients on renal replacement therapy (RRT), with significant economic and social impacts. The aim of this work was to analyze socioeconomic and mortality aspects of CKD patients in Santa Catarina (SC)...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2016.06.026

    authors: Silva AT,Soares LB,Magajewski FR

    更新日期:2016-09-01 00:00:00

  • Impact of immunosuppression on the development of Epstein-Barr virus (EBV) viremia after pediatric liver transplantation.

    abstract:OBJECTIVES:Pediatric liver transplant (OLT) patients are at risk of posttransplant lymphoproliferative disease (PTLD) from Epstein-Barr virus (EBV). This study examined the impact of induction and immunosuppression on EBV viremia. METHODS:A retrospective chart review was performed on 197 pediatric patients and inducti...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2012.04.035

    authors: Lu BR,Park KT,Hurwitz M,Cox KL,Berquist WE

    更新日期:2013-01-01 00:00:00

  • Investigation of the biomechanical integrity of decellularized rat abdominal aorta.

    abstract:OBJECTIVES:The loss or damage of an organ or tissue is one of the most common and devastating problems in healthcare today. Tissue engineering applies the principles of engineering and biology toward the development of functional biological replacements that are able to maintain, improve, or restore the function of pat...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2014.11.061

    authors: Katsimpoulas M,Morticelli L,Michalopoulos E,Gontika I,Stavropoulos-Giokas C,Kostakis A,Haverich A,Korossis S

    更新日期:2015-05-01 00:00:00

  • Disseminated nocardiosis: a rare infectious complication following non-heart-beating donor liver transplantation.

    abstract::Nocardiosis is an infrequent disease that affects patients who display a cellular immunodeficiency, such as transplant recipients on immunosuppressive treatment, but uncommonly associated with high morbidity and mortality rates. Disseminated Nocardiosis affecting the central nervous system (CNS), abdomen, skin, and lu...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2009.05.011

    authors: Jimenez-Galanes Marchan S,Meneu Díaz JC,Caso Maestro O,Perez Saborido B,Moreno Elola-Olaso A,Abradelo Usera M,Fundora Suarez Y,Gimeno Calvo A,Moreno Molinero V,Garcia Reyne A,Barra Valencia V,San Juan Garrido R,Moreno Gonzalez E

    更新日期:2009-07-01 00:00:00

  • The role of cysteinyl-LT(1)receptor (CysLT(1)R) in renal ischemia-reperfusion injury.

    abstract::The pathogenesis of ischemia-reperfusion (I/R) injury is known to involve cytokines and particularly surface adhesion molecules, the expression of which initiates the attachment of inflammatory cells. Renal I/R injury, a clinically important problem, is an invariable consequence of renal transplantation. The problem b...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2008.08.153

    authors: Matsuyama M,Funao K,Chargui J,Touraine JL,Nakatani T,Yoshimura R

    更新日期:2009-01-01 00:00:00

  • Real-time monitoring of nitric oxide (NO) and pO2 levels under ischemic conditions associated with small bowel ischemia/reperfusion injury using selective electrodes for NO and oxygen molecules.

    abstract::The present study demonstrated the feasibility of monitoring nitric oxide (NO) and pO2 levels under ischemic conditions associated with small bowel ischemia/reperfusion (I/R) injury through the use of selective electrodes for NO and oxygen molecules. NO levels gradually increased during ischemia. When reperfusion was ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2007.08.090

    authors: Watanabe T,Owada S,Kobayashi H,Ishiuchi A,Nakano H,Asakuta T,Shimamura T,Asano T,Koizumi S,Jinnouchi Y,Katayama M,Kamibayasi M,Murakami E,Otsubo T

    更新日期:2007-12-01 00:00:00

  • Islet preparation purity is overestimated, and less pure fractions have lower post-culture viability before clinical allotransplantation.

    abstract:BACKGROUND:Replacement of β-cells with the use of isolated islet allotransplantation (IT) is an emerging therapy for type 1 diabetics with hypoglycemia unawareness. The current standard protocol calls for a 36-72-hour culture period before IT. We examined 13 clinical islet preparations with ≥2 purity fractions to deter...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2014.06.011

    authors: Kitzmann JP,Karatzas T,Mueller KR,Avgoustiniatos ES,Gruessner AC,Balamurugan AN,Bellin MD,Hering BJ,Papas KK

    更新日期:2014-07-01 00:00:00

  • Newer antifungal agents for fungal infection prevention during hematopoietic cell transplantation: a meta-analysis.

    abstract:OBJECTIVE:The efficacy of newer antifungal agents to provide effective prophylaxis during stem cell transplantation has not yet been established. We compared the clinical outcomes using of the newer triazoles and echinocandins for antifungal prophylaxis. METHODS:We electronically searched the databases of Cochrane Cen...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.transproceed.2012.07.149

    authors: Xu SX,Shen JL,Tang XF,Feng B

    更新日期:2013-01-01 00:00:00

  • Influence of polyclonal antithymocyte globulins on the expression of adhesion molecules of isolated human umbilical vein endothelial cells.

    abstract:OBJECTIVES:Polyclonal antithymocyte globulins (ATGs) are immunosuppressive agents applied for the treatment and prevention of organ rejection after transplantation. ATGs induce complement-mediated cell death in T lymphocytes and decrease leukocyte adhesion. However, little is known about the effects of ATGs on endothel...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2009.11.038

    authors: Walther S,Beiras-Fernandez A,Csapo C,Münzing S,Stief CG,Hammer C,Reichart B,Thein E

    更新日期:2010-06-01 00:00:00

  • Cytomegalovirus infection renal transplant recipients: risk factors and outcome.

    abstract:OBJECTIVE:Cytomegalovirus (CMV) is the most common viral infection after allotransplantation; it can be a major cause of morbidity and mortality. Our aim was to analyze the main risk factors that lead to development of CMV infection and disease. PATIENTS AND METHODS:We retrospectively analyzed 207 patients who receive...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2009.06.057

    authors: Kanter J,Pallardó L,Gavela E,Escudero V,Beltrán S,Morales A,Avila A,Crespo JF

    更新日期:2009-07-01 00:00:00

  • Liver transplant combined with heart transplant in severe heterozygous hypercholesterolemia: report of the first case and review of the literature.

    abstract::Familial hypercholesterolemia (FH) is a dominant inherited disease of low-density lipoprotein (LDL) metabolism caused by mutations of LDL receptors mainly located in the liver. This metabolic disorder is responsible for severe cardiovascular disease, from coronary lesions to chronic heart failure (CHF). Liver transpla...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/j.transproceed.2005.03.037

    authors: Alkofer BJ,Chiche L,Khayat A,Deshayes JP,Lepage A,Saloux E,Reznik Y

    更新日期:2005-06-01 00:00:00

  • Blood pressure control according to the prevalence of diabetes in renal transplant recipients.

    abstract::Hypertension is one of the most frequent complications of renal transplantation. About 70% to 90% of this population display either high blood pressure (BP) or require antihypertensive therapy. Diabetes mellitus is also a common finding among kidney transplant recipients. The aim of the study was to assess the BP cont...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2012.05.089

    authors: Zbroch E,Malyszko J,Glowinska I,Maciorkowska D,Kobus G,Mysliwiec M

    更新日期:2013-01-01 00:00:00

  • Nitric oxide-mediated effects on liver blood flow.

    abstract::We investigated whether blockade of nitric oxide synthase by the arginine analog l- NAME could affect peripheral liver blood flow (PLBF) or hepatocyte integrity (serum ALT) in either a control series or in a series subjected to mild reduction of liver blood flow by temporary clamping of the hepatic artery (HA). Anesth...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2005.09.135

    authors: Gustafsson BI,Wallin M,Delbro DS,Friman S

    更新日期:2005-10-01 00:00:00

  • Hemophagocytic Syndrome as Uncommon Cause of Severe Pancytopenia After Liver Transplantation.

    abstract:BACKGROUND:A rare but life-threatening cause of pancytopenia after liver transplantation is hemophagocytic syndrome. We present a 48-year-old woman who underwent liver transplantation and developed a hemophagocytic syndrome secondary to Epstein-Barr virus with a fatal course, despite initial treatment with immunosuppre...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2020.02.060

    authors: Valenzuela EF,García AC,García-Pajares F,Tejada JT,Muñoz RN,Martín CM,Delgado LS,Martín CA,Álvarez CA,Fernández-Fontecha E,Sánchez-Antolín G

    更新日期:2020-06-01 00:00:00

  • The impact of "high-producer" interleukin-6 haplotypes on cardiovascular morbidity and mortality in a kidney transplant population.

    abstract:BACKGROUND:At present, inflammation is considered to be one of the key players in the development and maintenance of atherosclerosis, with ample impact on renal transplant outcomes. Interleukin-6 (IL-6) levels and the underlying genetically determined "high-producer" status impact cardiovascular morbidity and mortality...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2009.06.123

    authors: Krüger B,Walberer A,Farkas S,Tokmak F,Obed A,Schenker P,Henning B,Schlitt HJ,Krämer BK,Banas B

    更新日期:2009-07-01 00:00:00

  • Total parenteral nutrition: challenges and practice in the cirrhotic patient.

    abstract::Patients with cirrhosis develop metabolic derangements of protein, carbohydrate, and lipid metabolism. Malnutrition is commonplace and is associated with morbidity and mortality. Specific nutrient deficiencies may occur and enteral or parenteral nutritional support may improve outcome in appropriately selected patient...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/j.transproceed.2006.05.030

    authors: Buchman AL

    更新日期:2006-07-01 00:00:00

  • Thromboelastography as a Predictor of Outcomes Following Liver Transplantation.

    abstract:BACKGROUND:Thromboelastography (TEG) has been used perioperatively during liver transplantation (LT) to provide a real-time global hemostasis assessment for targeted blood product replacement. We aimed to analyze the relationship between post-LT TEG results and outcomes. METHODS:We retrospectively analyzed patients un...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2017.07.015

    authors: Trautman CL,Palmer WC,Taner CB,Canabal JM,Getz T,Goldman A,Heckman MG,Diehl NN,Lee DD,Stancampiano FF

    更新日期:2017-11-01 00:00:00

  • Analysis of the Organ Offers Received From European Union Countries Before and After the Introduction of a Dedicated Information Technology Portal: The COORENOR/FOEDUS Portal.

    abstract:INTRODUCTION:To optimize the use of nontransplantable organs in their own territory, the European Commission, as part of a project led by Italy, has promoted the use of an information technology (IT) portal, the COORENOR portal, developed by the Czech Republic in 2012, which evolved to become FOEDUS in 2015. METHODS:T...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2017.02.034

    authors: Peritore D,Rizzato L,Di Ciaccio P,Trapani S,Carella C,Oliveti A,Rizzo A,Nanni Costa A

    更新日期:2017-05-01 00:00:00

  • Converting family advocates to level 1 recovery coordinators.

    abstract:PURPOSE:The family advocate plays a crucial role in the organ and tissue procurement process for transplantation and research. This responsibility can weigh profoundly on the consent/conversion rates for family advocates. Some potential donor families consider time as a critical factor when deciding to donate. It was h...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2008.03.058

    authors: Caillouet-O'Neal C,Booker QG

    更新日期:2008-05-01 00:00:00

  • Islet of Langerhans allogeneic transplantation at the University of Geneva in the steroid free era in islet after kidney and simultaneous islet-kidney transplantations.

    abstract:AIMS:We report a single-center experience of islet allogeneic transplantation in islet after kidney (IAK) and simultaneous islet-kidney (SIK) type 1 diabetic recipients using a steroid-free immunosuppressive regimen. METHODS:Eight patients received 12 islet infusions in 5 IAK and 3 SIK procedures. Median age was 51 ye...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2004.04.027

    authors: Berney T,Bucher P,Mathe Z,Andres A,Bosco D,Mage R,Toso C,Oberholzer J,Becker C,Philippe J,Bühler L,Morel P

    更新日期:2004-05-01 00:00:00