Diltiazem attenuates the inotropic and peripheral vascular effects of cardiac glycosides.

abstract：BACKGROUND:Although age is the most important variable associated with death among patients with persistent ST-segment elevation, its impact on outcome among patients without persistent ST-segment elevation remains unknown. Moreover, the impact of age on the efficacy of antiplatelet therapy with eptifibatide is unknown...

journal_title：American heart journal

authors： Hasdai D,Holmes DR Jr,Criger DA,Topol EJ,Califf RM,Harrington RA

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Carvedilol therapy during congestive heart failure demonstrated a good efficacy in mortality rate reduction and in improvement of left ventricular (LV) systolic performance. However, currently there is not any finding about the drug's effect on diastolic filling. The aim of this study was to evaluate the eff...

journal_title：American heart journal

authors： Palazzuoli A,Carrera A,Calabria P,Puccetti L,Pastrorelli M,Pasqui AL,Auteri A,Bruni F

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:In adults, the most common cause of out-of-hospital cardiac arrests (OHCA) is acute coronary artery occlusion. If an immediate coronary angiogram (CAG) is recommended for survivors presenting a ST segment elevation on the electrocardiogram (ECG) performed after resuscitation, there is still a debate regardin...

journal_title：American heart journal

authors： Hauw-Berlemont C,Lamhaut L,Diehl JL,Andreotti C,Varenne O,Leroux P,Lascarrou JB,Guerin P,Loeb T,Roupie E,Daubin C,Beygui F,Vilfaillot A,Glippa S,Djadi-Prat J,Chatellier G,Cariou A,Spaulding C,EMERGE investigators.

更新日期：2020-04-01 00:00:00

abstract：:Nitrates are widely used for the management of congestive heart failure (CHF), as well as angina pectoris. In both situations, nitrates significantly increase exercise capacity. The mechanism of this beneficial effect is unclear, especially in CHF. Isosorbide dinitrate reduces pulmonary capillary wedge pressure (PCWP)...

journal_title：American heart journal

authors： Franciosa JA

更新日期：1985-07-01 00:00:00

abstract：:A-II exerts its activity on various target tissues by binding to its receptors. The discovery of local RASs and A-II receptors within various tissues has generated interest in the clinical usefulness of RAS inhibition by directly blocking the action of A-II at the receptor level. Different A-II receptor subtypes have ...

journal_title：American heart journal

authors： Kang PM,Landau AJ,Eberhardt RT,Frishman WH

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Percutaneous pulmonary valve implantation (PPVI) has been introduced as therapy for right ventricular (RV) to pulmonary artery conduit dysfunction in patients with congenital heart disease. It has been shown that RV systolic function improved early after PPVI. The effects of PPVI on RV diastolic function and...

journal_title：American heart journal

authors： Romeih S,Kroft LJ,Bokenkamp R,Schalij MJ,Grotenhuis H,Hazekamp MG,Groenink M,de Roos A,Blom NA

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:The prodrug clopidogrel requires activation by cytochrome P-450 (CYP) enzymes for its antiplatelet effect. The genes encoding enzymes for clopidogrel activation are polymorphic, leading to reduced or increased function, depending on the respective genotype. Reduced-function alleles have been associated with ...

journal_title：American heart journal

authors： Tiroch KA,Sibbing D,Koch W,Roosen-Runge T,Mehilli J,Schömig A,Kastrati A

更新日期：2010-09-01 00:00:00

abstract：:The short-term hemodynamic effects of molsidomine (4 mg sublingually) were evaluated in 13 patients with congestive heart failure following acute myocardial infarction. Right heart catheterization was performed by means of a Swan-Ganz thermodilution catheter. Hemodynamic measurements were made 30, 60, 120, and 180 min...

journal_title：American heart journal

authors： Cantelli I,Lolli C,Brunelli A,Bracchetti D

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers effectively reduce blood pressure in patients with renovascular disease (RVD); yet, randomized cardiovascular prevention trials of these drugs typically exclude individuals with this condition. PATIENTS AND METHODS:We studied the ass...

journal_title：American heart journal

authors： Hackam DG,Duong-Hua ML,Mamdani M,Li P,Tobe SW,Spence JD,Garg AX

更新日期：2008-09-01 00:00:00

abstract：:There are selective blocking agents (antagonists) for alpha receptors and beta receptors. These blocking agents prevent the response to injected agonists and neurogenically released norepinephrine. The principal cardiovascular response to alpha blockade is postural hypotension with reflexly induced cardiac stimulation...

journal_title：American heart journal

authors： Ahlquist RP

更新日期：1976-12-01 00:00:00

abstract：:The clinical profile and outcome of idiopathic restrictive cardiomyopathy in a group of eight children are reviewed. There were six girls and two boys. Age at presentation was 4.0 +/- 2.6 years (range 1.3 to 9.5 years). All patients had evidence of congestive heart failure with systemic venous congestion. Right or lef...

journal_title：American heart journal

authors： Lewis AB

更新日期：1992-06-01 00:00:00

abstract：:MAT is an uncommon arrhythmia most often seen in elderly patients with chronic pulmonary disease who are critically ill due to acute respiratory or cardiac decompensation. Its importance lies in the fact that it is commonly mistaken for AF, since both disorders are characterized by narrow ventricular complexes, irregu...

journal_title：American heart journal

authors： Scher DL,Arsura EL

更新日期：1989-09-01 00:00:00

abstract：:In prior studies, we have shown that the antikaliuretic drugs, triamterene and amiloride, through a direct cardiac effect reduce the loss of cardiac potassium induced by the administration of digitalis. Since loss of myocardial potassium is thought to underlie digitalis arrhythmias, this study was performed to determi...

journal_title：American heart journal

authors： Seller RH,Greco J,Banach S,Seth R

更新日期：1975-07-01 00:00:00

abstract：:Currently available antiplatelet agents are limited in the scope and magnitude of platelet inhibition. Orally active platelet glycoprotein IIb/IIIa antagonists are currently in clinical testing. These agents may extend platelet inhibition and clinical benefit from parenteral glycoprotein IIb/IIIa antagonists. The most...

journal_title：American heart journal

authors： Kereiakes DJ

更新日期：1999-07-01 00:00:00

abstract：:To evaluate the potential for hyperbaric oxygen (HBO) to produce transient improvement in function in areas of myocardium ischemic at rest (hibernating myocardium), 24 patients were studied within 1 week of acute myocardial infarction. Results were compared with single-photon emission computed tomography (SPECT) thall...

journal_title：American heart journal

authors： Swift PC,Turner JH,Oxer HF,O'Shea JP,Lane GK,Woollard KV

更新日期：1992-11-01 00:00:00

abstract：:Coronary atherosclerosis may cause acute and chronic ischemic syndromes; the former are caused by "acute plaque events," mostly thrombosis complicating vulnerable ruptured plaques, namely severe lesions with large core, thin cap, and weak shoulder infiltrated by activated inflammatory cells. Plaque rupture may also oc...

journal_title：American heart journal

authors： Arbustini E,Morbini P,Bello BD,Prati F,Specchia G

更新日期：1999-08-01 00:00:00

abstract：:To elucidate the long-term outcome and frequency of complications after heart transplantation for peripartum cardiomyopathy (PPCM), we compared the courses of eight consecutive patients undergoing transplantation for PPCM with those of nine female age-matched control subjects undergoing transplantation for idiopathic ...

journal_title：American heart journal

authors： Rickenbacher PR,Rizeq MN,Hunt SA,Billingham ME,Fowler MB

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Studies document better survival in heart failure patients with decreased left ventricular ejection fraction (EF) and higher body mass index (BMI; kg/m(2)) compared to those with a lower BMI. However, it is unknown if this "obesity paradox" applies to heart failure patients with preserved EF or if it extends...

journal_title：American heart journal

authors： Kapoor JR,Heidenreich PA

更新日期：2010-01-01 00:00:00

abstract：:The Institute of Medicine report on the frequency and consequences of medical errors in clinical practice has stimulated physicians to evaluate current practice and means of improving medical care. In the treatment of patients with acute myocardial infarction, previous studies have found that dosing of fibrinolytic th...

journal_title：American heart journal

authors： Cannon CP

更新日期：2000-12-01 00:00:00

abstract：:In 14 patients with severe congestive heart failure, the effects of captopril on the forearm circulation were evaluated with strain gauge plethysmography. Changes in plasma renin activity, angiotensin II, norepinephrine, epinephrine, bradykinin, prostaglandin E2, and 6-keto-prostaglandin F1 alpha concentrations were a...

journal_title：American heart journal

authors： Nishimura H,Kubo S,Ueyama M,Kubota J,Kawamura K

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Patients with kidney failure have a heavy burden of coronary artery disease. The results of preventive, diagnostic, and therapeutic measures developed in nonuremic populations cannot automatically be extrapolated to this unique group of patients. METHODS AND RESULTS:Articles were reviewed if they contained ...

journal_title：American heart journal

authors： Vaitkus PT

更新日期：2000-06-01 00:00:00

abstract：:The purpose of this study was to delineate the clinical, ECG, and angiographic features of a large series of consecutive patients with angina at rest. Transient ST segment elevation during pain was observed in 219 patients (group I), while 220 patients showed ST segment depression during pain (group II). Group II pati...

journal_title：American heart journal

authors： de Servi S,Ghio S,Ferrario M,Ardissino D,Angoli L,Mussini A,Bramucci E,Salerno J,Viganò M,Montemartini C

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:This study was designed to determine if vertically transmitted HIV infection and maternal infection with HIV are associated with altered cardiovascular structure and function in utero. METHODS:Fetal echocardiography was performed in 173 fetuses of 169 HIV-infected mothers (mean gestational age, 33.0 weeks; ...

journal_title：American heart journal

authors： Hornberger LK,Lipshultz SE,Easley KA,Colan SD,Schwartz M,Kaplan S,Starc TJ,Ayres NA,Lai WW,Moodie DS,Kasten-Sportes C,Sanders SP

更新日期：2000-10-01 00:00:00

abstract：:The aortocaval fistula is a classic model of pure cardiac volume overload in rats. This model is characterized by dilation of the ventricular cavities and eccentric cardiac hypertrophy. There are also changes in peripheral arterial flow: high flow in the proximal part of the aorta, upstream of the shunt, and low flow ...

journal_title：American heart journal

authors： Arnal JF,Philippe M,Laboulandine I,Michel JB

更新日期：1993-09-01 00:00:00

abstract：:The clinical usefulness of cardiac imaging modalities that rely upon the detection of perfusion defects and wall motion disturbances requires conditions that provoke a heterogeneity of coronary flow and a myocardial oxygen imbalance, respectively. Traditionally, this has been achieved by exercise stress testing. Many ...

journal_title：American heart journal

authors： van Rugge FP,van der Wall EE,Bruschke AV

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Older adults presenting with acute myocardial infarction (MI) often have multivessel coronary artery disease amenable to percutaneous coronary intervention (PCI), yet the risks of multivessel intervention may outweigh potential benefits in these patients. We sought to determine if nonculprit intervention dur...

journal_title：American heart journal

authors： Wang TY,McCoy LA,Bhatt DL,Rao SV,Roe MT,Resnic FS,Cavender MA,Messenger JC,Peterson ED

更新日期：2016-02-01 00:00:00

abstract：:Metoprolol or placebo was gradually withdrawn during 1 week in 115 patients participating in a 3-year, double-blind, postinfarction study. During the first month after withdrawal mental symptoms and increased cardiac symptoms occurred significantly more frequently in the metoprolol group. Disabling symptoms requiring ...

journal_title：American heart journal

authors： Olsson G,Hjemdahl P,Rehnqvist N

更新日期：1984-09-01 00:00:00

abstract：:The incremental advantage of transesophageal echocardiography was determined by comparing results of paired transthoracic and transesophageal echocardiographic examinations performed in 61 patients for evaluation of suspected infective endocarditis. According to clinical and pathologic data, 31 of 61 (51%) patients ha...

journal_title：American heart journal

authors： Birmingham GD,Rahko PS,Ballantyne F 3rd

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:We aim to validate the diagnostic performance of the first fully automatic, electronic heart failure (HF) identification algorithm and evaluate the implementation of an HF Dashboard system with 2 components: real-time identification of decompensated HF admissions and accurate characterization of disease char...

journal_title：American heart journal

authors： Cox ZL,Lewis CM,Lai P,Lenihan DJ

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Cardiac resynchronization therapy (CRT) improves symptoms, reduces heart failure (HF)-related hospitalizations, and reverses left ventricular remodeling in some patients with moderate to severe HF and ventricular dyssynchrony defined by a prolonged QRS duration. The effects of CRT on HF outcomes in patients ...

journal_title：American heart journal

authors： Linde C,Gold M,Abraham WT,Daubert JC,REVERSE Study Group.

更新日期：2006-02-01 00:00:00