Differential Activation of a Mouse Estrogen Receptor β Isoform (mERβ2) with Endocrine-Disrupting Chemicals (EDCs).

abstract：:Pavlovian conditioning processes may contribute to some symptoms of multiple chemical sensitivity (MCS). This review summarizes the potential relevance of the literature on conditional taste and olfactory aversions, conditional sensitization, and conditional immunomodulation to understanding MCS. A conditioning-based ...

journal_title：Environmental health perspectives

authors： Siegel S,Kreutzer R

更新日期：1997-03-01 00:00:00

abstract：:This article provides an overview of methods for reliability assessment of quantitative structure-activity relationship (QSAR) models in the context of regulatory acceptance of human health and environmental QSARs. Useful diagnostic tools and data analytical approaches are highlighted and exemplified. Particular empha...

journal_title：Environmental health perspectives

authors： Eriksson L,Jaworska J,Worth AP,Cronin MT,McDowell RM,Gramatica P

更新日期：2003-08-01 00:00:00

abstract：:I examined non-Hispanic Black and non-Hispanic White differences in exposure to noncriteria air pollutants in 44 U.S. Census Bureau-defined metropolitan areas with populations greater than one million, using data on air toxics concentrations prepared for the U.S. Environmental Protection Agency as part of its Cumulati...

journal_title：Environmental health perspectives

authors： Lopez R

更新日期：2002-04-01 00:00:00

abstract：:The neurochemical basis of memory has been approached experimentally in four different ways: the bioassay; the interventive approach; the interventive-correlative approach; and the correlative approach. These approaches are fundamentally similar to those used for the study of the chemistry of any behavior. Each of the...

journal_title：Environmental health perspectives

authors： Dunn AJ

更新日期：1978-10-01 00:00:00

abstract：:Our work has focused on the determination of physiological traits that may facilitate in situ degradation of xenobiotic compounds by indigenous microorganisms. For this our interests center on the following questions: What are the ambient conditions in a benzene, toluene, ethylbenzene, and xylene (BTEX)-contaminated a...

journal_title：Environmental health perspectives

authors： Olsen RH,Mikesell MD,Kukor JJ,Byrne AM

更新日期：1995-06-01 00:00:00

abstract：:The central feature of hemopoiesis is life-long, stable cell renewal. This process is supported by hemopoietic stem cells which, in the steady state, appear to be dormant in cell cycling. The entry into cell cycle of the dormant stem cells may be promoted by such factors as interleukin-1, interleukin-6 (IL-6), and gra...

journal_title：Environmental health perspectives

authors： Ogawa M

更新日期：1989-03-01 00:00:00

abstract：:Beginning approximately 4 years after the Chernobyl nuclear accident a steady increase in the incidence of thyroid cancer was observed in children and adolescents of the Bryansk Oblast, which received the highest level of radionuclide contaminants in Russia. We examined the spatial relationship between the residence l...

journal_title：Environmental health perspectives

authors： Parshkov EM,Chebotareva IV,Sokolov VA,Dallas CE

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVES:The National Environmental Policy Act and related state laws require many public agencies to analyze and disclose potentially significant environmental effects of agency actions, including effects on human health. In this paper we review the purpose and procedures of environmental impact assessment (EIA), ex...

journal_title：Environmental health perspectives

authors： Bhatia R,Wernham A

更新日期：2008-08-01 00:00:00

abstract：:Participants at the Napa Conference on Genetic and Molecular Ecotoxicology assessed the status of this field in light of heightened concerns about the genetic effects of exposure to hazardous substances and recent advancements in our capabilities to measure those effects. We present here a synthesis of the ideas discu...

journal_title：Environmental health perspectives

authors： Anderson S,Sadinski W,Shugart L,Brussard P,Depledge M,Ford T,Hose J,Stegeman J,Suk W,Wirgin I

更新日期：1994-12-01 00:00:00

abstract：:Considerable attention has been given to the relationship between levels of fine particulate matter (particulate matter < or = 2.5 microm in aerodynamic diameter; PM(2.5) in the atmosphere and health effects in human populations. Since the U.S. Environmental Protection Agency began widespread monitoring of PM(2.5) lev...

journal_title：Environmental health perspectives

authors： Holloman CH,Bortnick SM,Morara M,Strauss WJ,Calder CA

更新日期：2004-09-01 00:00:00

abstract：:A system suitable for the detection of meiotic aneuploidy is described in which various different origins of the aneuploidy can be distinguished. Aneuploid meiotic products are detected as black disomic spores held in asci containing all the products of a single meiosis. Aneuploidy may result from nondisjunction or fr...

journal_title：Environmental health perspectives

authors： Bond DJ,McMillan L

更新日期：1979-08-01 00:00:00

abstract：:The integrated exposure uptake biokinetic model for lead in children was developed to provide plausible blood lead distributions corresponding to particular combinations of multimedia lead exposure. The model is based on a set of equations that convert lead exposure (expressed as micrograms per day) to blood lead conc...

journal_title：Environmental health perspectives

authors： White PD,Van Leeuwen P,Davis BD,Maddaloni M,Hogan KA,Marcus AH,Elias RW

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Climate influences dengue ecology by affecting vector dynamics, agent development, and mosquito/human interactions. Although these relationships are known, the impact climate change will have on transmission is unclear. Climate-driven statistical and process-based models are being used to refine our knowledg...

journal_title：Environmental health perspectives

authors： Morin CW,Comrie AC,Ernst K

更新日期：2013-11-01 00:00:00

abstract：:To assess the possibility that increases in UV-B exposure on the earth's surface could lead to impaired resistance to several infectious diseases, we studied the effect of UV-B exposure on resistance against Trichinella spiralis. Wistar rats, orally infected with T. spiralis larvae, were exposed to suberythemal doses ...

journal_title：Environmental health perspectives

authors： Goettsch W,Garssen J,Deijns A,de Gruijl FR,van Loveren H

更新日期：1994-03-01 00:00:00

abstract：:Adults eating a Western diet digest and absorb ingested food containing approximately 100 g fat, 350 g carbohydrate, and 75 g protein daily. Normal fat absorption requires adequate gastric, pancreatic, liver-biliary, mucosal, and lymphatic function. Carbohydrate and protein absorption is much less dependent on liver-b...

journal_title：Environmental health perspectives

authors： Heizer WD

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:Although adverse effects of high temperature on mortality have been studied extensively in urban areas, little is known of the heat-mortality associations outside of cities. OBJECTIVE:We investigated whether heat-mortality associations differed between urban and nonurban areas and how urbanicity affected th...

journal_title：Environmental health perspectives

authors： Chen K,Zhou L,Chen X,Ma Z,Liu Y,Huang L,Bi J,Kinney PL

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:In the 1990s, the mercury-based preservative thimerosal was used in most pediatric vaccines. Although there are currently only two thimerosal-containing vaccines (TCVs) recommended for pediatric use, parental perceptions that vaccines pose safety concerns are affecting vaccination rates, particularly in ligh...

journal_title：Environmental health perspectives

authors： Curtis B,Liberato N,Rulien M,Morrisroe K,Kenney C,Yutuc V,Ferrier C,Marti CN,Mandell D,Burbacher TM,Sackett GP,Hewitson L

更新日期：2015-06-01 00:00:00

abstract：:The main source of cadmium in the diet is cereal or meat, especially in liver and kidney. Since the cadmium in both liver and kidney is bound to metallothionein, a heat-stable protein, the gastrointestinal absorption and metabolism of cadmium metallothionein (CdMt) was studied in detail. The selective renal cadmium de...

journal_title：Environmental health perspectives

authors： Cherian MG

更新日期：1979-02-01 00:00:00

abstract：:For decades, a number of guinea pig tests have been used to identify human contact allergens in workplace and consumer products, but these tests have limitations. In addition to using large numbers of test animals, they also provide only subjective measurements, because the allergic activity is measured by watching th...

journal_title：Environmental health perspectives

authors： Clay R

更新日期：1998-10-01 00:00:00

abstract：:Chemoprotective phytochemicals exhibit multiple activities and interact with several cellular receptors, including the aryl hydrocarbon (Ah) receptor (AhR). In this study we investigated the AhR agonist/antagonist activities of the following flavonoids: chrysin, phloretin, kaempferol, galangin, naringenin, genistein, ...

journal_title：Environmental health perspectives

authors： Zhang S,Qin C,Safe SH

更新日期：2003-12-01 00:00:00

abstract：:Biological monitoring of genotoxic hazard in the rubber industry was performed in 19 male workers and 20 age-matched controls in a local health unit in northern Italy. Peripheral blood lymphocytes were analyzed for the presence of DNA damage (single-cell microgel-electrophoresis, or comet assay) and for cytogenetic pa...

journal_title：Environmental health perspectives

authors： Moretti M,Villarini M,Scassellati-Sforzolini G,Monarca S,Libraro M,Fatigoni C,Donato F,Leonardis C,Perego L

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Lead (Pb) exposure has been associated with a host of pathological conditions in humans. In rodents Pb exposure has been shown to alter the hypothalamic-pituitary-adrenal (HPA) axis function. OBJECTIVE:We investigated the effects of lead on responses of the HPA axis to a psychosocial laboratory stressor adm...

journal_title：Environmental health perspectives

authors： Fortin MC,Cory-Slechta DA,Ohman-Strickland P,Nwankwo C,Yanger TS,Todd AC,Moynihan J,Walton J,Brooks A,Fiedler N

更新日期：2012-02-01 00:00:00

abstract：:Organophosphate (OP) pesticides are commonly used in the United States, and farmworkers are at risk for chronic exposure. Using a sample of 218 farmworkers in 24 communities and labor camps in eastern Washington State, we examined the association between agricultural crop and OP pesticide metabolite concentrations in ...

journal_title：Environmental health perspectives

authors： Coronado GD,Vigoren EM,Thompson B,Griffith WC,Faustman EM

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Studies estimating health effects of long-term air pollution exposure often use a two-stage approach: building exposure models to assign individual-level exposures, which are then used in regression analyses. This requires accurate exposure modeling and careful treatment of exposure measurement error. OBJEC...

journal_title：Environmental health perspectives

authors： Bergen S,Sheppard L,Sampson PD,Kim SY,Richards M,Vedal S,Kaufman JD,Szpiro AA

更新日期：2013-09-01 00:00:00

abstract：:Although most people are thought to receive their highest acute exposures to gasoline while refueling, relatively little is actually known about personal, nonoccupational exposures to gasoline during refueling activities. This study was designed to measure exposures associated with the use of an oxygenated fuel under ...

journal_title：Environmental health perspectives

authors： Backer LC,Egeland GM,Ashley DL,Lawryk NJ,Weisel CP,White MC,Bundy T,Shortt E,Middaugh JP

更新日期：1997-08-01 00:00:00

abstract：:We found an epidemic of juvenile hypothyroidism among a population of self-defined "downwinders" living near the Hanford nuclear facility located in southeast Washington State. The episode followed massive releases of 131I. Self-reported data on 60 cases of juvenile hypothyroidism (<20 years of age) among a group of 8...

journal_title：Environmental health perspectives

authors： Goldsmith JR,Grossman CM,Morton WE,Nussbaum RH,Kordysh EA,Quastel MR,Sobel RB,Nussbaum FD

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Arsenicals (roxarsone and nitarsone) used in poultry production likely increase inorganic arsenic (iAs), monomethylarsonic acid (MMA), dimethylarsinic acid (DMA), and roxarsone or nitarsone concentrations in poultry meat. However, the association between poultry intake and exposure to these arsenic species, ...

journal_title：Environmental health perspectives

authors： Nigra AE,Nachman KE,Love DC,Grau-Perez M,Navas-Acien A

更新日期：2017-03-01 00:00:00

abstract：:The fundamental problems in population monitoring for genetic effects are twofold: the binomialized nature of the data and the lower power due to small risk of finding positive results. The binomial character is artificial, even forced, and can with advantage be replaced by more refined analysis, and by a focus on all...

journal_title：Environmental health perspectives

authors： Murphy EA

更新日期：1981-12-01 00:00:00

abstract：:Granular activated carbon (GAC), in the presence of dilute aqueous hypochlorite solutions typical of those used in water treatment, was converted to a reagent capable of carrying out free-radical coupling reactions and other oxidations of dilute aqueous solutions of phenols. The products included biphenyls with chlori...

journal_title：Environmental health perspectives

authors： Voudrias EA,Larson RA,Snoeyink VL,Chen AS,Stapleton PL

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Benchmark dose (BMD) modeling is an important step in human health risk assessment and is used as the default approach to identify the point of departure for risk assessment. A probabilistic framework for dose-response assessment has been proposed and advocated by various institutions and organizations; ther...

journal_title：Environmental health perspectives

authors： Shao K,Shapiro AJ

更新日期：2018-01-11 00:00:00