Abstract:
:Although exercise is often recommended for managing osteoarthritis (OA), limited evidence-based exercise options are available for older adults with OA. This study compared the effects of Hatha yoga (HY) and aerobic/strengthening exercises (ASE) on knee OA. Randomized controlled trial with three arms design was used: HY, ASE, and education control. Both HY and ASE groups involved 8 weekly 45-min group classes with 2-4 days/week home practice sessions. Control group received OA education brochures and weekly phone calls from study staff. Standardized instruments were used to measure OA symptoms, physical function, mood, spiritual health, fear of falling, and quality of life at baseline, 4 and 8 weeks. HY/ASE adherences were assessed weekly using class attendance records and home practice video recordings. Primary analysis of the difference in the change from baseline was based on intent-to-treat and adjusted for baseline values. Eight-three adults with symptomatic knee OA completed the study (84% female; mean age 71.6 ± 8.0 years; mean BMI 29.0 ± 7.0 kg/m2). Retention rate was 82%. Compared to the ASE group at 8 weeks, participants in the HY group had a significant improvement from baseline in perception of OA symptoms (-9.6 [95% CI -15.3, -4]; p = .001), anxiety (-1.4 [95% CI -2.7, -0]; p = .04), and fear of falling (-4.6 [-7.5, -1.7]; p = .002). There were no differences in class/home practice adherence between HY and ASE. Three non-serious adverse events were reported from the ASE group. Both HY and ASE improved symptoms and function but HY may have superior benefits for older adults with knee OA. Trial registration The full trial protocol is available at clinicaltrials.gov (NCT02525341).
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Cheung C,Wyman JF,Bronas U,McCarthy T,Rudser K,Mathiason MAdoi
10.1007/s00296-016-3620-2subject
Has Abstractpub_date
2017-03-01 00:00:00pages
389-398issue
3eissn
0172-8172issn
1437-160Xpii
10.1007/s00296-016-3620-2journal_volume
37pub_type
杂志文章,随机对照试验abstract::Osteopoikilosis, a form of osteosclerotic disorders, is a rare bone dysplasia with typical radiologic findings. The pathology, which sometimes requires attention in differential diagnosis due to its radiologic appearance, has been reported previously with other diseases. In this report, a case diagnosed with both reac...
journal_title:Rheumatology international
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00270984
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journal_title:Rheumatology international
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abstract::Using commercially available antigens, enzyme-linked immunosorbent assays (ELISAs) were set up to demonstrate antibodies of IgG class against Sm and SS-A. Anti-Sm antibodies were demonstrated in 40% of patients with systemic lupus erythematosus (SLE), in 12% of patients with SJögren's syndrome, in 6% of patients with ...
journal_title:Rheumatology international
pub_type: 杂志文章
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abstract::Sleep disturbances and problems are increased in ankylosing spondylitis (AS). But much is not known in a quantitative way about sleep problems and effect of treatments on AS. This study is aimed first, to investigate sleep disturbances in AS and secondly, to evaluate the effects of anti-TNF treatment on SD in AS. One ...
journal_title:Rheumatology international
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journal_title:Rheumatology international
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journal_title:Rheumatology international
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abstract::Seronegative spondylarthropathies are disorders with the same predisposing antigen, namely HLA B27, a class I molecule of the HLA system. The mechanisms of the different diseases are unknown, and there is no proof of immune system participation. We have investigated patients with spondylarthropathies in order to searc...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00390264
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journal_title:Rheumatology international
pub_type: 临床试验,杂志文章
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abstract::It is known that patients with rheumatoid arthritis (RA) have an increased risk for non-Hodgkin's lymphomas in comparison with the general population. Although increased risk of lymphoma is attributed to the disease activity, the drugs used in the therapy of RA may also cause increased risk of malignancy. Herein, we r...
journal_title:Rheumatology international
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journal_title:Rheumatology international
pub_type: 杂志文章
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journal_title:Rheumatology international
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abstract::To study the mechanisms of chondrocyte damage, chondrocyte cytotoxicity as shown by chromium-51 release induced by polymorphonuclear leukocytes (PMNLs) was examined. PMNLs significantly enhanced chondrocyte cytotoxicity in the presence of phorbol dibutyrate. This chondrocyte damage was abolished by the addition of cat...
journal_title:Rheumatology international
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journal_title:Rheumatology international
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pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Rheumatology international
pub_type: 杂志文章,评审
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journal_title:Rheumatology international
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journal_title:Rheumatology international
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journal_title:Rheumatology international
pub_type: 杂志文章
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journal_title:Rheumatology international
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