Endogenous Bioactive Jasmonate Is Composed of a Set of (+)-7-iso-JA-Amino Acid Conjugates.

Abstract:

:Jasmonates (JAs) regulate a wide range of plant defense and development processes. The bioactive JA is perceived by its receptor COI1 to trigger the degradation of JASMONATE ZIM-DOMAIN (JAZ) proteins and subsequently derepress the JAZ-repressed transcription factors for activation of expression of JA-responsive genes. So far, (+)-7-iso-JA-l-Ile has been the only identified endogenous bioactive JA molecule. Here, we designed coronafacic acid (CFA) conjugates with all the amino acids (CFA-AA) to mimic the JA amino acid conjugates, and revealed that (+)-7-iso-JA-Leu, (+)-7-iso-JA-Val, (+)-7-iso-JA-Met, and (+)-7-iso-JA-Ala are new endogenous bioactive JA molecules. Furthermore, our studies uncover the general characteristics for all the bioactive JA molecules, and provide a new strategy to synthetically generate novel active JA molecules.

journal_name

Plant Physiol

journal_title

Plant physiology

authors

Yan J,Li S,Gu M,Yao R,Li Y,Chen J,Yang M,Tong J,Xiao L,Nan F,Xie D

doi

10.1104/pp.16.00906

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

2154-2164

issue

4

eissn

0032-0889

issn

1532-2548

pii

pp.16.00906

journal_volume

172

pub_type

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