Association between ambient air pollution and proliferation of umbilical cord blood cells.


:It has been established as a common knowledge that ambient air pollution (AAP) has an adverse effect on human health. The pathophysiological mechanism of this impact is likely to be related to the oxidative stress. In the current study we estimate the association between AAP and cell proliferation (CP) of umbilical cord blood cells, representing maternal organism most proximal to the fetal body. Blood samples were tested for proliferation in 292 enrolled Arab-Bedouin women at delivery (July 2012-March 2013). The estimates of AAP were defined by a hybrid satellite based model predicting both PM2.5 (particles<2.5µm in diameter) and PM10 (particles<10µm in diameter) as well as monitoring stations for gaseous air pollutants. Risk estimates of pollution exposure were adjusted to medical history, household risk factors and meteorological factors on the day of delivery or one week prior. Ambient ozone (O3) levels on 1, 2, 3and 4 days prior to delivery were associated with lower CP (Prevalence ratio (PR)=0.92, 0.92, 0.93, 0.93, respectively). Increase in inter-quartile range (IOR) of PM2.5 one day before delivery was associated with 9% increase in CP levels (PR=1.09). The positive direction in association was changed to negative association with CP for PM2.5 levels measured at more distant time periods (PR=0.90 and 0.93 for lags 5 and 6 days, respectively). Investigation of PM10 levels indicated a similar pattern (PR=1.05 for pollution values recorded one day before delivery and 0.93 and 0.95 for lags of 5 and 6 days, respectively). Carbon monoxide (CO) levels were associated with lower CP on the day of delivery and 1day prior (PR=0.92 and PR=0.94). To conclude, the levels of cell proliferation of umbilical cord blood cells appear to be associated with the AAP. More studies are needed to support our findings.


Environ Res


Environmental research


Novack L,Yitshak-Sade M,Landau D,Kloog I,Sarov B,Karakis I




Has Abstract


2016-11-01 00:00:00












  • Structural and social-economic determinants of China's transport low-carbon development under the background of aging and industrial migration.

    abstract::This paper aims to explore structural and social-economic determinants of China's transport CO2 emissions (TCEs) from 2004 to 2016, by using logarithmic mean Divisa index (LMDI). Compared with existing studies, two new factors, i.e., spatial pattern and age structure, that should have impacts on TCEs, are considered i...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Feng C,Xia YS,Sun LX

    更新日期:2020-09-01 00:00:00

  • Quantification of eight bisphenol analogues in blood and urine samples of workers in a hazardous waste incinerator.

    abstract::Bisphenol A (BPA) has been widely used in the manufacture of polycarbonate plastic and epoxy resins. In recent years, producers have started replacing BPA by other chemical analogues, such as bisphenol -S (BPS) and -F (BPF), all of them under the label "BPA-free". However, despite bisphenol (BP) analogues have a very ...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: González N,Cunha SC,Monteiro C,Fernandes JO,Marquès M,Domingo JL,Nadal M

    更新日期:2019-09-01 00:00:00

  • Early life low-level cadmium exposure is positively associated with increased oxidative stress.

    abstract::Environmental exposure to cadmium (Cd) is known to induce oxidative stress, a state of imbalance between the production of reactive oxygen species (ROS) and the ability to detoxify them, in adults. However, data are lacking on potential effects in early-life. We evaluated urinary concentrations of 8-oxo-7,8-dihydro-2'...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Kippler M,Hossain MB,Lindh C,Moore SE,Kabir I,Vahter M,Broberg K

    更新日期:2012-01-01 00:00:00

  • Risk to consumers from mercury in bluefish (Pomatomus saltatrix) from New Jersey: Size, season and geographical effects.

    abstract::Relatively little attention has been devoted to the risks from mercury in saltwater fish, that were caught by recreational fisherfolk. Although the US Food and Drug Administration has issued advisories based on mercury for four saltwater species or groups of fish, there are few data on how mercury levels vary by size,...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Burger J

    更新日期:2009-10-01 00:00:00

  • Blood cadmium concentrations and environmental exposure sources in newcomer South and East Asian women in the Greater Toronto Area, Canada.

    abstract:BACKGROUND:Immigrant women are often identified as being particularly vulnerable to environmental exposures and health effects. The availability of biomonitoring data on newcomers is limited, thus, presenting a challenge to public health practitioners in the identification of priorities for intervention. OBJECTIVES:In...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Wiseman CLS,Parnia A,Chakravartty D,Archbold J,Zawar N,Copes R,Cole DC

    更新日期:2017-04-01 00:00:00

  • Lead concentrations and isotopic signatures in vintages of French wine between 1950 and 1991.

    abstract::Vintages of French wine from 1950 to 1991 were analyzed for lead isotopes and concentrations to investigate whether they might be used to archive the isotopic composition of the anthropogenic lead in aerosols to which the vineyard was exposed. Early vintages (1950-1980) contained 78-227 ng/g of lead with 206Pb/207Pb r...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Rosman KJ,Chisholm W,Jimi S,Candelone JP,Boutron CF,Teissedre PL,Adams FC

    更新日期:1998-08-01 00:00:00

  • Urinary concentrations of bisphenol A in an urban minority birth cohort in New York City, prenatal through age 7 years.

    abstract:BACKGROUND:Despite growing concern over potential health effects associated with exposures to the endocrine disruptor, bisphenol A (BPA), insufficient information is available on determinants of BPA concentrations among minority populations in the US. OBJECTIVES:To describe concentrations and predictors of BPA in an i...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Hoepner LA,Whyatt RM,Just AC,Calafat AM,Perera FP,Rundle AG

    更新日期:2013-04-01 00:00:00

  • Prenatal exposure to manganese at environment relevant level and neonatal neurobehavioral development.

    abstract:BACKGROUND:Effects of prenatal Manganese (Mn) exposure at an environmental relevant level on neonatal neurodevelopment remains unclear. OBJECTIVES:In the multi-center study, we assessed the impact of low level prenatal Mn exposure on neonatal behavioral neurological assessments (NBNA), and explore a threshold umbilica...

    journal_title:Environmental research

    pub_type: 杂志文章,多中心研究


    authors: Yu XD,Zhang J,Yan CH,Shen XM

    更新日期:2014-08-01 00:00:00

  • Geochemistry and origin of PM10 in the Huelva region, Southwestern Spain.

    abstract::The results of chemical analysis of PM(10) atmospheric dust samples collected between July 2001 and June 2002 in rural and urban background monitoring stations in Huelva (South-western Spain) are reported. In order to identify the sources and quantify their contribution to PM(10), principal component analysis and rece...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Sánchez de la Campa AM,de la Rosa J,Querol X,Alastuey A,Mantilla E

    更新日期:2007-03-01 00:00:00

  • Intrauterine bisphenol A exposure leads to stimulatory effects on Sertoli cell number in rats.

    abstract::Using the optical disector for quantifying cell numbers, we investigated whether oral treatment of rats on days 6-21 of gestation with the weakly estrogenic bisphenol A (BPA, 0.1 or 50 mg/kg) or the highly estrogenic ethinyl estradiol (EE, 0.02 mg/kg) alters testicular histology, in those offspring 9-12 month of age. ...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Wistuba J,Brinkworth MH,Schlatt S,Chahoud I,Nieschlag E

    更新日期:2003-02-01 00:00:00

  • Planning for the health impacts of climate change: Flooding, private groundwater contamination and waterborne infection - A cross-sectional study of risk perception, experience and behaviours in the Republic of Ireland.

    abstract::The frequency and severity of flooding events will increase over the coming decades due to global climate change. While close attention has typically been paid to infrastructural and environmental outcomes of flood events, the potential adverse human health consequences associated with post-event consumption from priv...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Musacchio A,Andrade L,O'Neill E,Re V,O'Dwyer J,Hynds PD

    更新日期:2021-01-08 00:00:00

  • Effect of lead on bone and cartilage in sexually mature rats: a morphometric and histomorphometry study.

    abstract::The effect of exposure to lead on the longitudinal development of the femur and of its cartilage growth plate was studied in rats. A group of forty-five 50-day-old female Wistar rats was divided into a control group of 20 rats and an experimental group of 25 rats fed a diet supplemented with 17 mg of lead acetate per ...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: González-Riola J,Hernández ER,Escribano A,Revilla M,Ca-Seco,Villa LF,Rico H

    更新日期:1997-01-01 00:00:00

  • Mortality among frequent consumers of Great Lakes sport fish.

    abstract::Commercial and sport-caught fish provide a healthy source of dietary protein, omega-3 fatty acids, and other micronutrients. Regular fish consumption has been associated with decreased risk of heart disease and health professionals encourage adults to include fish in their weekly diets. However, fish harvested from co...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Tomasallo C,Anderson H,Haughwout M,Imm P,Knobeloch L

    更新日期:2010-01-01 00:00:00

  • Oxidative stress indices in natural populations of Avicennia alba Blume. as biomarker of environmental pollution.

    abstract::Effects of multiple pollutants including heavy metal on oxidative stress indices were measured in leaves and roots of Avicennia alba Blume. collected from three coastal locations in Kerala-Cochin, Kollam and Chetua. We observed significant activities in lipid peroxidation, root oxidizability, electrolyte leakage and a...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Harish SR,Murugan K

    更新日期:2011-11-01 00:00:00

  • Sulfur-rich geothermal emissions elevate acid aerosol levels in metropolitan Taipei.

    abstract::Several studies have demonstrated that millions of people globally are potentially exposed to volcanic gases. Hydrogen sulfide is a typical gas in volcanic and geothermal areas. The gas is toxic at high concentrations that predominantly affects the nervous, cardiovascular, and respiratory systems. The WHO air quality ...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Lin CH,Mao IF,Tsai PH,Chuang HY,Chen YJ,Chen ML

    更新日期:2010-08-01 00:00:00

  • Some statistical issues related to multiple linear regression modeling of beach bacteria concentrations.

    abstract::As a fast and effective technique, the multiple linear regression (MLR) method has been widely used in modeling and prediction of beach bacteria concentrations. Among previous works on this subject, however, several issues were insufficiently or inconsistently addressed. Those issues include the value and use of inter...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Ge Z,Frick WE

    更新日期:2007-03-01 00:00:00

  • Static and dynamic studies of lanthanum(III) ion adsorption/desorption from acidic solutions using chelating ion exchangers with different functionalities.

    abstract::Increasing the number of applications of rare earth elements (REEs) has led to increased release of these metals into the environment. Removal of REEs from e-wastes is very important considering the increasing demand for these elements, the limited resource availability of them as well as the significant environmental...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Kołodyńska D,Fila D,Hubicki Z

    更新日期:2020-12-01 00:00:00

  • Phenols and parabens in relation to reproductive and thyroid hormones in pregnant women.

    abstract:INTRODUCTION:Phenols and parabens are ubiquitous environmental contaminants. Evidence from animal studies and limited human data suggest they may be endocrine disruptors. In the current study, we examined associations of phenols and parabens with reproductive and thyroid hormones in 106 pregnant women recruited for the...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Aker AM,Watkins DJ,Johns LE,Ferguson KK,Soldin OP,Anzalota Del Toro LV,Alshawabkeh AN,Cordero JF,Meeker JD

    更新日期:2016-11-01 00:00:00

  • Blood lead levels among children aged 1 to 5 years in Wuxi City, China.

    abstract::The objective of this study was to determine mean blood lead levels and prevalence of elevated blood lead levels among 1- to 5-year-old children in Wuxi City, China. By use of a representative cross-sectional survey that included measurements of capillary blood lead, 1117 children aged 1-5 years were examined from Oct...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Gao W,Li Z,Kaufmann RB,Jones RL,Wang Z,Chen Y,Zhao X,Wang N

    更新日期:2001-09-01 00:00:00

  • Antibiotic-resistant Escherichia coli and Klebsiella spp. in greywater reuse systems and pond water used for agricultural irrigation in the West Bank, Palestinian Territories.

    abstract::Treating and reusing greywater for agricultural irrigation is becoming increasingly prevalent in water-scarce regions such as the Middle East. However, the potential for antibiotic-resistant bacteria to be introduced into food systems or the environment via greywater reuse is a potential area of concern. It is known t...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Craddock HA,Chattopadhyay S,Rjoub Y,Rosen D,Greif J,Lipchin C,Mongodin EF,Sapkota AR

    更新日期:2020-09-01 00:00:00

  • Environmental implications of stored cattle slurry treatment with sulphuric acid and biochar: A life cycle assessment approach.

    abstract::With the increase of animal slurry produced from livestock production, the monitoring and mitigation of greenhouse gas (GHG) and ammonia (NH3) emissions represent a major issue. Life cycle assessment (LCA) has been used to evaluate the long-term environmental effects of applied strategies and technologies on cattle sl...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Miranda C,Soares AS,Coelho AC,Trindade H,Teixeira CA

    更新日期:2021-01-02 00:00:00

  • Effect of cadmium on the immune response in rats.

    abstract::Adult male inbred Wistar rats were given a subtoxic dose of cadmium (25 ppm) orally for 4 weeks prior to and during immunization with sheep erythrocytes (E). The control group received tap water during the experimental period. No difference in the antibody response to E was found between the two groups. Mononuclear pe...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Wesenberg GB,Wesenberg F

    更新日期:1983-08-01 00:00:00

  • Evaluation of exposure to road traffic noise: Effects of microphone height and urban configuration.

    abstract::Noise pollution is a major environmental problem due to its impact on human health and implications for other spheres of society. Since road traffic is the main source of noise pollution, the use of measurement methodologies to accurately determine the environmental noise levels to which the façades of buildings in ci...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Montes González D,Barrigón Morillas JM,Rey Gozalo G,Godinho L

    更新日期:2020-12-01 00:00:00

  • Residential exposure to chromium waste--urine biological monitoring in conjunction with environmental exposure monitoring.

    abstract::To determine whether a population living on or adjacent to four sites of chromate production waste was measurably exposed to environmental chromium, spot samples of urine were collected along with wipe samples of household dust and lifestyle/activity interview data. Findings were compared to those from a control popul...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Stern AH,Freeman NC,Pleban P,Boesch RR,Wainman T,Howell T,Shupack SI,Johnson BB,Lioy PJ

    更新日期:1992-08-01 00:00:00

  • Hydroxyl-radical-dependent DNA damage by ambient particulate matter from contrasting sampling locations.

    abstract::Exposure to ambient particulate matter (PM) has been reported to be associated with increased respiratory, cardiovascular, and malignant lung disease. Previously we have shown that PM can induce oxidative DNA damage in A549 human lung epithelial cells. The aims of the present study were to investigate the variability ...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Shi T,Duffin R,Borm PJ,Li H,Weishaupt C,Schins RP

    更新日期:2006-05-01 00:00:00

  • Residential radon and lung cancer incidence in a Danish cohort.

    abstract::High-level occupational radon exposure is an established risk factor for lung cancer. We assessed the long-term association between residential radon and lung cancer risk using a prospective Danish cohort using 57,053 persons recruited during 1993-1997. We followed each cohort member for cancer occurrence until 27 Jun...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Bräuner EV,Andersen CE,Sørensen M,Andersen ZJ,Gravesen P,Ulbak K,Hertel O,Pedersen C,Overvad K,Tjønneland A,Raaschou-Nielsen O

    更新日期:2012-10-01 00:00:00

  • Radiofrequency exposure in the Neonatal Medium Care Unit.

    abstract::The aims of this study were to characterize electromagnetic fields of radiofrequency (RF-EMF) levels generated in a Neonatal Medium Care Unit and to analyze RF-EMF levels inside unit's incubators. Spot and long-term measurements were made with a dosimeter. The spot measurement mean was 1.51±0.48V/m. Higher values were...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Calvente I,Vázquez-Pérez A,Fernández MF,Núñez MI,Múñoz-Hoyos A

    更新日期:2017-01-01 00:00:00

  • Lead exposure is related to hypercortisolemic profiles and allostatic load in Brazilian older adults.

    abstract::Lead levels (Pb) have been linked to both hyper- and hypo-reactivity of hypothalamic-pituitary-adrenal axis (HPA) axis to acute stress in animals and humans. Similarly, allostatic load (AL), the 'wear and tear' of chronic stress, is associated with inadequate HPA axis activity. We examined whether Pb levels would be a...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Souza-Talarico JN,Suchecki D,Juster RP,Plusquellec P,Barbosa Junior F,Bunscheit V,Marcourakis T,de Matos TM,Lupien SJ

    更新日期:2017-04-01 00:00:00

  • Urinary cobalt and ferritin in four-years-old children.

    abstract::Cobalt (Co) is an essential trace element but may cause toxic effects upon occupational or environmental exposure. The present study is aimed to determine the urine concentrations of Co in four years-old children in the INMA-Asturias cohort (Spain) and to assess the factors determining the observed levels. This cohort...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Junqué E,Grimalt JO,Fernández-Somoano A,Tardón A

    更新日期:2020-04-01 00:00:00

  • Factors affecting plasma benzo[a]pyrene levels in environmental studies.

    abstract::Benzo[a]pyrene (BaP) is a useful indicator of exposure to polycyclic aromatic hydrocarbons (PAHs), airborne carcinogenic compounds. Radioimmunoassay was used to test for plasma BaP differences in 61 subjects divided into three groups based on geographic-demographic locale: urban-industrial, urban-residential, and oute...

    journal_title:Environmental research

    pub_type: 杂志文章


    authors: Hutcheon DE,Kantrowitz J,Van Gelder RN,Flynn E

    更新日期:1983-10-01 00:00:00