Inverse association between toenail arsenic and body mass index in a population of welders.

Abstract:

:Recent data show that arsenic may play a role in obesity-related diseases. However, urinary arsenic studies report an inverse association between arsenic level and body mass index (BMI). We explored whether toenail arsenic, a long-term exposure measure, was associated with BMI in 74 welders with known arsenic exposure. BMI showed significant inverse associations with toenail arsenic (p=0.01), which persisted in models adjusted for demographics, diet and work history. It is unclear whether low arsenic biomarker concentrations in high BMI subjects truly reflect lower exposures, or instead reflect internal or metabolic changes that alter arsenic metabolism and tissue deposition.

journal_name

Environ Res

journal_title

Environmental research

authors

Grashow R,Zhang J,Fang SC,Weisskopf MG,Christiani DC,Kile ML,Cavallari JM

doi

10.1016/j.envres.2014.03.010

subject

Has Abstract

pub_date

2014-05-01 00:00:00

pages

131-3

eissn

0013-9351

issn

1096-0953

pii

S0013-9351(14)00056-5

journal_volume

131

pub_type

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