Abstract:
:The aim of this study was to examine the relationship between insulin sensitivity and polychlorinated biphenyls (PCBs) exposure in non-diabetic pregnant women. Forty gravidas, 21-39 years of age and residing within the study area, were recruited. Seventeen 2,3,7,8-substituted dichloro-p-dioxin, dibenzofurans and 12 PCBs were measured using high-resolution gas chromatography/high-resolution mass spectrometry (HRGC/HRMS). Serum insulin and glucose were also measured. Insulin sensitivity and the quantitative insulin sensitivity check index (QUICKI) were calculated based on fasting glucose and insulin levels. Three specific congeners of PCBs (123, 126, and 169) were significantly associated with insulin activity (r=-0.34 approximately -0.36, p<0.05). Statistical analyses revealed that insulin sensitivity was significantly associated with age- and pre-pregnancy body mass indices (BMI)-adjusted for decreasing toxic equivalents (TEQ) of PCBs (p=0.02 for age- and BMI-adjusted). We also performed an insulin correlation for total TEQ and the TEQ of PCBs, and determined that insulin sensitivity was predicted by the TEQ of PCBs by a regression coefficient of -0.189 after adjustment for age and pre-pregnancy BMI. These findings suggest that PCBs may be associated with decreasing insulin sensitivity in non-diabetic pregnant women; however, the mechanism remains to be ascertained.
journal_name
Environ Resjournal_title
Environmental researchauthors
Chen JW,Wang SL,Liao PC,Chen HY,Ko YC,Lee CCdoi
10.1016/j.envres.2008.01.004subject
Has Abstractpub_date
2008-06-01 00:00:00pages
245-53issue
2eissn
0013-9351issn
1096-0953pii
S0013-9351(08)00006-6journal_volume
107pub_type
杂志文章abstract::Nitrogen dioxide (NO2) and black carbon (BC) concentrations were measured inside London taxicabs across 40 work shifts in a real-world occupational study. The shifts were measured across five plug-in hybrid range-extender electric taxicabs (TXe City) and five diesel taxicabs (TX4 Diesel). The aim of this study was to ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2021.110736
更新日期:2021-01-20 00:00:00
abstract::It has been established as a common knowledge that ambient air pollution (AAP) has an adverse effect on human health. The pathophysiological mechanism of this impact is likely to be related to the oxidative stress. In the current study we estimate the association between AAP and cell proliferation (CP) of umbilical co...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2016.09.009
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Given the lack of research on the personal exposure to fine particles (PM2.5) in Hong Kong, we examined the association between short-term personal exposure to PM2.5 and their constituents and inflammation in exhaled breath in a sample of healthy adult residents. METHOD:Forty-six participants underwent pers...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.02.009
更新日期:2018-07-01 00:00:00
abstract::Complex mixture exposures, such as those associated with water sources, are an important issue in health risk assessment. This study assessed the cytotoxicity of chemical mixtures extracted from water sources in regions of the Huai River Basin with high cancer incidences and built statistical models of cytotoxicity ba...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2014.12.027
更新日期:2015-02-01 00:00:00
abstract::Lake Mead National Recreational Area (LMNRA) serves as critical habitat for several federally listed species and supplies water for municipal, domestic, and agricultural use in the Southwestern U.S. Contaminant sources and concentrations vary among the sub-basins within LMNRA. To investigate whether exposure to enviro...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.01.041
更新日期:2018-05-01 00:00:00
abstract::The effect of chronic exposure to 2 ppm nitrogen dioxide (NO2) for 8 hr a day, 5 days a week, for 8 weeks was assessed in normal and emphysematous hamsters by measuring (1) lung morphometry (mean linear intercept [Lm] and internal surface area [ISA]), (2) lung mechanics (lung volume, compliance and coefficient of stat...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(87)80059-2
更新日期:1987-06-01 00:00:00
abstract:BACKGROUND:Exposure to far-field radiofrequency electromagnetic fields (RF-EMF) has raised public concerns in recent decades. However, it is not known if individuals' perception towards the health risks of RF-EMF is dependent on their knowledge of the objectively measured personal RF-EMF exposure levels. OBJECTIVES:Th...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.12.058
更新日期:2019-03-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110316
更新日期:2021-01-01 00:00:00
abstract::We assessed levels and determinants of mercury biomarkers among residents of Montreal and surroundings who eat sportfish from the nearby St. Lawrence River. Participants were selected from 1118 adult fishers responding to a 1996 screening questionnaire; the study sample (n=132) overrepresented respondents expected to ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.2000.4073
更新日期:2000-09-01 00:00:00
abstract::The MXene-based transition metal oxide composite is a potential candidate for photocatalysts. Rod-like pseudohexagonal phase Nb2O5/Nb2CTx composites were synthesized by a simple hydrothermal oxidation of 2D layered Nb2CTx. The Nb2O5/Nb2CTx composites show superior photocatalytic activity for 98.5% of degradation of Rh...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110587
更新日期:2021-02-01 00:00:00
abstract::Heat waves are considered to be increasing in frequency and intensity whereas they comprise a significant weather-related cause of deaths in several countries. Two heat waves occurred in Greece in summer 2007. These severe heat waves are assessed by analyzing the prevailing synoptic conditions, evaluating human therma...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2009.12.002
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:We previously reported increased risk of breast cancer associated with early life exposure to two measures of air pollution exposure, total suspended particulates (TSP) and traffic emissions (TE), possible proxies for exposure to polycyclic aromatic hydrocarbons (PAHs). Exposure to PAHs has been shown to be ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.11.040
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Heightened blood lead levels (BLL) are associated with cognitive deficiencies and adverse behavioral outcomes. Lead-contaminated house dust is the primary source of exposure in U.S. children, and evidence suggests that even background (low-level) exposure has negative consequences. Identifying sources of bac...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.12.069
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Although air pollution and social stress may independently increase childhood asthma, little is known on their synergistic effect on asthma, particularly in China with high levels of stress and air pollution. OBJECTIVES:To examine associations between exposure to a combination of parental stress and air pol...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.04.003
更新日期:2018-08-01 00:00:00
abstract::Despite the behaviors of ZnO nanoparticles (ZnO NPs) in wastewater treatment processes have been widely explored, the impacts of ZnO NPs on the activated sludge's flocculation and sedimentation performances for solid-liquid separation have rarely been involved yet. In this study, ZnO NPs were observed to exert a dose-...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110256
更新日期:2021-01-01 00:00:00
abstract::At the end of December 2019, the rapid spread of the COVID-19 (SARS-CoV-2) disease and, subsequently, deaths around the world, lead to the declaration of the pandemic situation in the world. At the beginning of the epidemic, much attention is paid to person-to-person transmission, disinfection of virus-contaminated su...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110612
更新日期:2021-02-01 00:00:00
abstract::The relationship of inorganic arsenic exposure through drinking water and total urinary arsenic excretion in a nonoccupationally exposed population was evaluated in a cross-sectional study in three mayor cities of Chile (Antofagasta, Santiago, and Temuco). A total of 756 individuals in three population strata (elderly...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2005.02.007
更新日期:2005-06-01 00:00:00
abstract::Relatively little attention has been devoted to the risks from mercury in saltwater fish, that were caught by recreational fisherfolk. Although the US Food and Drug Administration has issued advisories based on mercury for four saltwater species or groups of fish, there are few data on how mercury levels vary by size,...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2009.07.005
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:Polychlorinated biphenyls (PCBs) may interact with several thyroid functions. Severe environmental pollution by PCBs has been observed in Brescia, Italy, due to the presence of a factory that produced these compounds until 1984. OBJECTIVES:We aimed to investigate the correlation between serum levels of tota...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2008.08.003
更新日期:2008-11-01 00:00:00
abstract::n-Hexane is used in industry as a solvent for adhesive, dry cleaning, and vegetable oil extraction. In 1963, the first case of severe polyneuropathy suspected to be caused by n-hexane was referred to us. Case studies, animal experiments, and field surveys on n-hexane poisoning were conducted, and preventive measures l...
journal_title:Environmental research
pub_type: 杂志文章,评审
doi:10.1006/enrs.1993.1091
更新日期:1993-07-01 00:00:00
abstract::Alien species contribute to global change in all marine ecosystems. Environmental variability can affect species distribution and population sizes, and is therefore expected to influence alien species. In this study, we have investigated temporal variability of 11 alien species representing different trophic levels an...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2011.03.002
更新日期:2011-10-01 00:00:00
abstract::Air quality monitoring is part of the initial strategy in the pollution prevention program in Indonesia. Since 1978, the government of Indonesia has had a commitment to the World Health Organization (WHO) to provide air quality data for the Global Environmental Monitoring System (GEMS Programme)--The WHO/UNEP Project,...
journal_title:Environmental research
pub_type: 杂志文章,评审
doi:10.1006/enrs.1993.1131
更新日期:1993-10-01 00:00:00
abstract::1,2-Cyclohexane dicarboxylic acid, diisononyl ester (DINCH) is a complex mixture of nine carbon branched-chain isomers. It has been used in Europe since 2002 as a plasticizer to replace phthalates such as di(2-ethylhexyl)phthalate (DEHP) and diisononyl phthalate (DINP). Urinary concentrations of the oxidative metaboli...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2013.05.007
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:Gut microorganisms contribute to the metabolism of environmental toxicants, including methylmercury (MeHg). Our main objective was to investigate whether associations between biomarkers for prenatal MeHg exposure and maternal gut microbiota differed between early and late gestation. METHODS:Maternal blood an...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.01.014
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Extracellular vesicles (EVs) represent a plausible molecular mechanism linking particulate matter (PM) inhalation to its systemic effects. Microvesicles (MVs) are released from many cell types in response to various stimuli. Increased body mass index (BMI) could modify the response to PM exposure due to enha...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.02.014
更新日期:2017-05-01 00:00:00
abstract::Inhalation of welding fume (WF) can result in the deposition of toxic metals, such as manganese (Mn), in the brain and may cause neurological changes in exposed workers. Alterations in telomere length are indicative of cellular aging and, possibly, neurodegeneration. Here, we investigated the effect of WF inhalation o...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108900
更新日期:2020-01-01 00:00:00
abstract::In this study, a size-selective bioaerosol sampler was built and combined with adenosine triphosphate (ATP) bioluminescence assay for measuring the bioaerosol concentration more rapidly and easily. The ATP bioaerosol sampler consisted of a respirable cyclone, an impactor to collect bioaerosols onto the head of a swab ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110615
更新日期:2020-12-10 00:00:00
abstract::Enantio-selective molecular dynamics of (±)-o,p-DDT uptake and degradation in water-sediment system is described. Both uptake and degradation processes of (-)-o,p-DDT were slightly higher than (+)-o,p-DDT enantiomer. The optimized parameters for uptake were 7.0μgL-1 concentration of o,p-DDT, 60min contact time, 5.0pH,...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.10.022
更新日期:2018-01-01 00:00:00
abstract::Indicators for cooking fuel pollution are needed to determine the extent of fuel-related problems in developing countries and to assess the success of measures undertaken to reduce such problems. It is proposed that eye irritation in the form of tears or smarting eyes during cooking time [tears while cooking (TWC)] is...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.1997.3771
更新日期:1997-10-01 00:00:00
abstract::Hydrological and thermal river regimes have changed greatly due to the construction of reservoirs and dams. Water temperature changes have important significance for aquatic habitats and freshwater ecosystems. To investigate the impact of large reservoirs on the water temperature regime along the middle reach of the Y...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109221
更新日期:2020-04-01 00:00:00