Abstract：
BACKGROUND:There is growing evidence that persistent organic pollutants (POPs) may play an important role in increasing the risk of gestational diabetes mellitus (GDM). OBJECTIVES:The aim of this study was to examine the association between polychlorinated biphenyls (PCBs, 10 congeners) and polybrominated diphenyl ethers (PBDEs, 8 congeners) and GDM in primiparous women with no family history of diabetes in first-degree relatives during the third trimester of pregnancy. METHODS:This case-control study was performed among the three university hospitals of Tehran University of Medical Sciences. Serum samples were collected from cases (n=70) that were diagnosed with GDM and from controls (n=70) with a normal pregnancy that attended the same hospital for a routine prenatal visit. Pollutant levels were analyzed by Gas Chromatography Mass Spectrometry (GC/MS). RESULTS:Logistic regression analyses manifested the positive association between total POPs (sum of total PCBs and PBDEs) (Odds ratio (OR)=1.61, 95% CI: 1.31-1.97, p-value <0.0001) and total PCBs (OR=1.75, 95% CI: 1.35-2.27, p-value<0.0001) and GDM considering confounding variables (age, gestational age, pre-pregnancy body mass index (BMI), and total maternal serum lipid). In addition, we found a positive association between total PBDEs and GDM (OR =2.21; 95% CI: 1.48-3.30, p-value <0.0001). Finally, we found a positive association between Ln PCB 187, 118 and Ln PBDE 99, 28 with GDM. Meanwhile a negative association between Ln PCB 28 and GDM was established. CONCLUSION:Our data suggest that exposure to certain POPs (PCBs and PBDEs) could be a potential modifying risk factor for GDM.
journal_name
Environ Resjournal_title
Environmental researchauthors
Eslami B,Naddafi K,Rastkari N,Rashidi BH,Djazayeri A,Malekafzali Hdoi
10.1016/j.envres.2016.09.002subject
Has Abstractpub_date
2016-11-01 00:00:00pages
706-712eissn
0013-9351issn
1096-0953pii
S0013-9351(16)30540-0journal_volume
151pub_type
杂志文章abstract：:The cytotoxic activity of the DQ-12 standard dust on the external structure of peritoneal macrophages, after intraperitoneal introduction, was investigated, vs nontreated macrophages, and kept in in vitro cultures for 3, 6, and 24 hr. The alterations related to the external structure were investigated by scanning elec...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(83)90002-6
更新日期：1983-08-01 00:00:00
abstract：:Chronic exposure to hydrogen sulfide (H(2)S) in the parts per billion-parts per million range occurs in the population of Rotorua, a city built upon an actively degassing geothermal field in the Taupo Volcanic Zone, New Zealand. H(2)S is acutely toxic at high concentrations but little is understood of the health effec...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2005.08.006
更新日期：2006-06-01 00:00:00
abstract：:Penetration of 2,4,5,2',4',5'-[14C]hexachlorobiphenyl (HCB) through skin of young (33 days) and adult (82 days) female Fischer 344 rats was determined in vivo and by two in vitro methods. In vivo dermal penetration at 120 hr was 45% in young and 43% in adults. At 72 hr in vivo dermal penetration was 35% in young and 2...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(89)80053-2
更新日期：1989-10-01 00:00:00
abstract：BACKGROUND:Cohorts based on administrative data have size advantages over individual cohorts in investigating air pollution risks, but often lack in-depth information on individual risk factors related to lifestyle. If there is a correlation between lifestyle and air pollution, omitted lifestyle variables may result in...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.03.050
更新日期：2017-07-01 00:00:00
abstract：:Phthalates are potentially involved in the development of type 2 diabetes mellitus. In a cohort of 123 obese subjects, 10 phthalate metabolites were analyzed. An oral glucose tolerance test was performed and various estimates of insulin resistance and beta-cell function were calculated. After adjustment for age, physi...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2015.01.010
更新日期：2015-02-01 00:00:00
abstract：:This study was designed to evaluate the effects of a diet rich in fish contaminated with MeHg, mimicking the typical diet of the Amazon riverside population, in rats. Animals were randomly assigned to one of three groups with eight rats in each group: Group I-control, received commercial ration; Group II-received a di...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2011.09.013
更新日期：2011-11-01 00:00:00
abstract：:Pylons of utility lines are commonly used by breeding birds as structures for supporting their nests. Nesting near power lines, however, exposes adult birds and their offspring to the electric and magnetic fields (EMFs) produced by the current. Therefore, we searched for possible relationships between the magnetic fie...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2007.02.006
更新日期：2007-07-01 00:00:00
abstract：CONTEXT AND OBJECTIVE:Asthma among children is a major public health problem worldwide. There are increasing number of studies suggesting a possible association between allergenic pollen and exacerbations of asthma. In the context of global climate change, a number of future climate and air pollution scenarios predict ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2007.10.005
更新日期：2008-02-01 00:00:00
abstract：:The Water Framework Directive 2000/60/EC implemented by the European Union established as the main objectives to achieve a "good ecological and chemical status" of the surface water and a "good quantitative and chemical status" of groundwater bodies. One of the major pressures affecting water bodies comes from the use...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.108570
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:Tobacco smoke exposure increases the risk of cancer in the liver, but little is known about the possible risk associated with exposure to ambient air pollution. OBJECTIVES:We evaluated the association between residential exposure to air pollution and primary liver cancer incidence. METHODS:We obtained data...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.01.006
更新日期：2017-04-01 00:00:00
abstract：BACKGROUND:Epidemiologic studies on the association between metals and body mass index (BMI) have been cross-sectional and have demonstrated inconsistent associations. Our study prospectively examined whether metals measured at baseline were associated with later BMI. We considered metals individually and as joint expo...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109396
更新日期：2020-05-01 00:00:00
abstract：BACKGROUND:Dichlorodiphenyltrichloroethane (DDT) and polychlorinated biphenyls (PCBs) are persistent organochlorine compounds bioaccumulating in human tissues. Body burden of organochlorines may be influenced by individual characteristics such as age, weight variations, breastfeeding, dietary habits and place of reside...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2011.06.001
更新日期：2011-08-01 00:00:00
abstract：:Household solid fuel use is a major source of many air pollutants causing severe air pollution and adverse health outcomes. In evaluation of health impacts of household air pollution, it is essential to characterize toxic properties like mutagenicity of residential fuel combustion emissions and exposure assessments. M...
journal_title：Environmental research
pub_type： 杂志文章,评审
doi：10.1016/j.envres.2017.05.001
更新日期：2017-07-01 00:00:00
abstract：BACKGROUND:Long-term exposure to ambient fine particulate matter (≤ 2.5 μg/m3 in aerodynamic diameter; PM2.5) is significantly associated with increased risk of premature mortality. Our goal was to provide an updated meta-analysis of all-cause and cause-specific mortality associated with exposure to PM2.5 and to better...
journal_title：Environmental research
pub_type： 杂志文章,meta分析
doi：10.1016/j.envres.2018.06.021
更新日期：2018-10-01 00:00:00
abstract：:Day-old Japanese quail were fed purified diets containing either 0.2 (control), 5.4, or 16.2 ppm lead as the acetate with either 25 (deficient) or 100 ppm (adequate control) iron for 2 weeks. Iron deficiency caused decreases in hemoglobin, iron, and manganese in the liver, and hepatic RNA synthesis. Iron deficiency al...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(84)90030-6
更新日期：1984-04-01 00:00:00
abstract：OBJECTIVE:Gut microorganisms contribute to the metabolism of environmental toxicants, including methylmercury (MeHg). Our main objective was to investigate whether associations between biomarkers for prenatal MeHg exposure and maternal gut microbiota differed between early and late gestation. METHODS:Maternal blood an...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.01.014
更新日期：2019-05-01 00:00:00
abstract：:Many residential hazards are disproportionately concentrated in older, urban dwellings and share common underlying causes, such as uncorrected moisture problems and inadequate maintenance and cleaning. Comprehensive and affordable approaches to remediation are needed, but the feasibility and efficacy of such approache...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2005.03.003
更新日期：2005-11-01 00:00:00
abstract：:To determine which of the faster and slower large myelinated nerve fibers (alpha fiber group) are more sensitive to chronic lead exposure, the distribution of nerve conduction velocities (DCV) as well as conventional sensory nerve conduction velocity (SCV) were measured once a month for 20 and 11 months in two male le...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1993.1118
更新日期：1993-08-01 00:00:00
abstract：BACKGROUND:Exposure to PM2.5 (fine particulate matter journal_title：Environmental research pub_type： 杂志文章 doi：10.1016/j.envres.2017.11.050 更新日期：2018-02-01 00:00:00
abstract：:We investigated the serum concentrations of two brominated flame retardants (BFRs) - polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecane (HBCDD) -in 59 women aged between 23 and 42 from the United Kingdom. We also collected demographic data, including age, bodyweight and height in order to test for assoc...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.108631
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:The prevalence of diabetes is on rise worldwide and environmental factors are being increasingly recognized to be involved in this rise. An emerging body of evidence has evaluated the impact of long-term exposure to noise on diabetes mellitus, highlighting the need to synthesize this evidence. OBJECTIVES:To...
journal_title：Environmental research
pub_type： 杂志文章,meta分析
doi：10.1016/j.envres.2018.05.011
更新日期：2018-10-01 00:00:00
abstract：:The aims of this study were (1) to explore the behavioral and sociodemographic factors influencing urinary cotinine (COT-U) levels in active smokers and in environmental tobacco smoke (ETS)-exposed individuals, (2) to assess the specificity and sensitivity of the questionnaire for identifying active smokers and nonsmo...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2016.03.029
更新日期：2016-07-01 00:00:00
abstract：:Ciguatera fish poisoning (CFP) is one of the most devastating food-borne illnesses caused by fish consumption. Ciguatoxins (CTXs) are potent neurotoxins synthesized by the benthic microalgae Gambierdiscus spp. and Fukuyoa spp. that are transmitted to fish by grazing and predation. Despite the high incidence of CFP, af...
journal_title：Environmental research
pub_type： 杂志文章,评审
doi：10.1016/j.envres.2020.109111
更新日期：2020-03-01 00:00:00
abstract：:Mercury content of twelve podzols from NW Spain was studied to elucidate the main soil properties involved in the Hg accumulation of these soils. The highest average Hg concentrations (HgT) were found in the Bh and Bs horizons (64 and 105 μg kg-1), whereas the lowest occurred in the E horizons (15 μg kg-1). Moderate v...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110552
更新日期：2021-02-01 00:00:00
abstract：:The pathogenicity of mixed dust from a fluorite mine was studied by animal experiments and in vitro tests. Animal experiments showed that calcium fluorite can induce only a foreign body reaction in the lungs; the fibrous nodular lesions induced by the fluorite mine dust are due mainly to its silica component. It was d...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(87)80035-x
更新日期：1987-08-01 00:00:00
abstract：:Cardiovascular diseases (CVD) are responsible for around 20% of all deaths worldwide (approximately 14 million) and are the principal cause of death in all developed countries, accounting for 50% of all deaths. Variations in the annual per capita death rates in different countries are well documented. Less well known ...
journal_title：Environmental research
pub_type： 杂志文章,评审
doi：10.1016/s0013-9351(02)00009-9
更新日期：2003-05-01 00:00:00
abstract：:Lead arsenate (PbHAsO4) was used as an insecticide in Washington fruit orchards from 1905 to 1947. We examined exposure potential for children living in an agricultural community with historic PbHAsO4 use. Soil and housedust samples were collected from 58 residences. Families were asked about land use history, age of ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(03)00064-1
更新日期：2003-11-01 00:00:00
abstract：:Environmental exposure to cadmium (Cd) is known to induce oxidative stress, a state of imbalance between the production of reactive oxygen species (ROS) and the ability to detoxify them, in adults. However, data are lacking on potential effects in early-life. We evaluated urinary concentrations of 8-oxo-7,8-dihydro-2'...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2011.11.012
更新日期：2012-01-01 00:00:00
abstract：:To know the short- as well as long-term effect of aqueous latex extracts of Euphorbia tirucalli on carbohydrate and protein metabolism, the snail Lymnaea acuminata was exposed to sublethal doses of 0.37 and 0.55 mg/L for a 24-h and 0.20 and 0.31 mg/L for a 96-h exposure period. Significant (P<0.05) alterations in the ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2004.12.008
更新日期：2005-11-01 00:00:00
abstract：BACKGROUND:Dichlorodiphenyl dichloroethylene (DDE) and polychlorinated biphenyls (PCBs) can be passed from mother to offspring through placental transfer or breastfeeding. Unknown is whether maternal levels can predict concentrations in adult offspring. OBJECTIVES:To test the association between maternal blood levels ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2014.03.009
更新日期：2014-07-01 00:00:00
