Abstract:
:Environmental exposure to cadmium (Cd) is known to induce oxidative stress, a state of imbalance between the production of reactive oxygen species (ROS) and the ability to detoxify them, in adults. However, data are lacking on potential effects in early-life. We evaluated urinary concentrations of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG), a recognized marker of oxidative DNA damage, in relation to Cd exposure in 96 predominantly breast-fed infants (11-17 weeks of age) in rural Bangladesh. Urinary 8-oxodG was measured using liquid chromatography tandem mass spectrometry and Cd in urine and breast milk by inductively coupled plasma mass spectrometry. Median concentration of 8-oxodG was 3.9 nmol/L, urinary Cd 0.30 μg/L, and breast-milk Cd 0.13 μg/L. In linear regression analyses, urinary 8-oxodG was positively associated with Cd in both urine (p=0.00067) and breast milk (p=0.0021), and negatively associated with body weight (kg; p=0.0041). Adjustment for age, body weight, socio-economic status, urinary arsenic, as well as magnesium, calcium, and copper in breast milk did not change the association between Cd exposure and urinary 8-oxodG. These findings suggest that early-life low-level exposure to Cd via breast milk induces oxidative stress. Further studies are warranted to elucidate whether this oxidative stress is associated with impaired child health and development.
journal_name
Environ Resjournal_title
Environmental researchauthors
Kippler M,Hossain MB,Lindh C,Moore SE,Kabir I,Vahter M,Broberg Kdoi
10.1016/j.envres.2011.11.012subject
Has Abstractpub_date
2012-01-01 00:00:00pages
164-70eissn
0013-9351issn
1096-0953pii
S0013-9351(11)00305-7journal_volume
112pub_type
杂志文章abstract::In response to criticisms raised regarding a case-control study of canine malignant lymphoma, the results of several ancillary analyses are reported. The case-control study demonstrated a significant association between risk for canine malignant lymphoma and the opportunity for exposure to 2,4-dichlorophenoxyacetic ac...
journal_title:Environmental research
pub_type: 杂志文章,多中心研究
doi:10.1006/enrs.1995.1056
更新日期:1995-08-01 00:00:00
abstract::The purpose of this study was to examine possible risk factors for lung cancer among nonsmokers. The Illinois State Cancer Registry was used to identify all nonsmoking lung cancer cases diagnosed between 1985 and 1987. Subjects were classified as nonsmokers only if their medical record specifically stated that they ha...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.1993.1001
更新日期:1993-01-01 00:00:00
abstract::Atopic dermatitis is one of the most common inflammatory skin diseases among children and adults. Although the risk factors for atopic dermatitis have not yet been fully identified, exposure to mercury may be an important environmental risk factor. The objective of this study was to evaluate the association between me...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2011.02.003
更新日期:2011-05-01 00:00:00
abstract::Several studies have reported associations between farming and respiratory health in neighboring residents. Health effects are possibly linked to fine dust and endotoxin emissions from livestock farms. Little is known about levels of these air pollutants in ambient air in livestock dense areas. We aimed to explore tem...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2016.12.004
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:The questioned link between air pollution and coronavirus disease 2019 (COVID-19) spreading or related mortality represents a hot topic that has immediately been regarded in the light of divergent views. A first "school of thought" advocates that what matters are only standard epidemiological variables (i.e....
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110556
更新日期:2021-02-01 00:00:00
abstract::Food safety assessment and communication have a strong importance in reducing human health risks related to food consumption. The research carried out within the ECsafeSEAFOOD project aims to assess seafood safety issues, mainly related to non-regulated priority environmental contaminants, and to evaluate their impact...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2015.06.038
更新日期:2015-11-01 00:00:00
abstract::Formaldehyde poses significant threats to the ecosystem and is widely used as a toxicity indicator to obtain electrical signal feedback in electroactive biofilm (EAB)-based sensors. Although many optimizations have been adopted to improve the performance of EAB to formaldehyde, nearly no studies have discussed the tox...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109143
更新日期:2020-04-01 00:00:00
abstract::In this study, a size-selective bioaerosol sampler was built and combined with adenosine triphosphate (ATP) bioluminescence assay for measuring the bioaerosol concentration more rapidly and easily. The ATP bioaerosol sampler consisted of a respirable cyclone, an impactor to collect bioaerosols onto the head of a swab ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110615
更新日期:2020-12-10 00:00:00
abstract::The purpose of this investigation was to examine the relationship between airway responsiveness and the permeability of histamine through the airways in conscious sheep after exposure to ozone (O3). Airway responsiveness was assessed by measuring the change from baseline in mean pulmonary flow resistance following a c...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(84)90080-x
更新日期:1984-06-01 00:00:00
abstract::Bisphenol A (BPA) and Di-(2-ethylhexyl) phthalate (DEHP) are two wide spread chemicals classified as endocrine disruptors (ED). The present study aims to estimate the non-dietary (dermal, non-dietary ingestion and inhalation) exposure to BPA and DEHP for a pregnant women cohort. In addition, to assess the prenatal exp...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.05.008
更新日期:2018-10-01 00:00:00
abstract::The high exposure risks of workers to herbicides in low- and middle-income countries is an important public health concern because of the potential resulting negative impacts on workers' health. This study investigated workers' personal protective equipment (PPE) compliance as a risk mitigation measure; particularly w...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2015.05.028
更新日期:2015-10-01 00:00:00
abstract::Labrador Tea (Rhododendron groenlandicum) has been an important food and medicinal plant to First Nations communities in North America for millenia, but little is known of its geochemical properties. Using plants from 10 sites in 4 provinces, including pristine and industrial regions, and employing the metal-free, ult...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109272
更新日期:2020-04-01 00:00:00
abstract::Epidemiologic studies have suggested that exposure to solvent-based materials in the painting trades is associated with an increased cancer risk. In order to determine if the solvent exposures of current union members of the International Brotherhood of Painters and Allied Tradesman (IBPAT) are associated with a genot...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(89)80005-2
更新日期:1989-12-01 00:00:00
abstract:BACKGROUND:There has been no investigation to date of adults with metabolic syndrome examining the association of short and long-term exposure to fine particulate matter (PM2.5) air pollution with cardiovascular-disease related inflammatory marker (WBC and CRP) levels in a nationally representative sample. The goal of ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.11.042
更新日期:2018-02-01 00:00:00
abstract::Traditional food consumption for Indigenous peoples is associated with improved nutrition and health but can also pose potential risks via exposure to contaminants. Polycyclic aromatic hydrocarbons (PAHs) are compounds of interest due to their widespread presence (e.g., their metabolites are detected in up to 100% of ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109112
更新日期:2020-03-01 00:00:00
abstract::Methylmercury (MeHg) is the most bioavailable and toxic form of the globally distributed pollutant Hg. Organisms of higher trophic levels living in aquatic ecosystems have potentially higher concentrations of MeHg. In this work, we analysed both MeHg and inorganic Mercury (Hg(II)) concentrations from dorsal feathers o...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109526
更新日期:2020-07-01 00:00:00
abstract::The median nerve somatosensory evoked potentials (SEP), pattern reversal visual evoked potentials (VEP), and brain stem auditory evoked potentials (BAEP) were studied in 109 healthy adults and in 88 patients with acute carbon monoxide (CO) poisoning. The upper limits for normal values of peak and interpeak latencies o...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.1993.1029
更新日期:1993-02-01 00:00:00
abstract:BACKGROUND:The number of studies on air pollution with birth defects as the primary outcome has increased dramatically over the past two decades, but the potential role of specific air pollutants in congenital limb anomalies remains unclear. OBJECTIVES:To evaluate associations between preconception and first-trimester...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109643
更新日期:2020-08-01 00:00:00
abstract::There is growing evidence that exposure to persistent organic pollutants (POPs) is statistically associated with incidence of cardiovascular disease (CVD) or its risk factors. Decarbromodiphenyl ether (BDE-209) is a new POP which exists extensively in human tissues, but its potential effects on CVD have so far receive...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.10.035
更新日期:2019-02-01 00:00:00
abstract::Urinary β2-microgroblin (β2-MG) excretion levels above 300 μg/g creatinine are used to indicate defective tubular reabsorption. Arguably, increased urinary β2-MG excretion could also reflect glomerular filtration rate decline. Thus, we investigated an association between urinary β2-MG and estimated glomerular filtrati...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.03.026
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:In 1979, approximately 2,000 people in central Taiwan were accidentally exposed to polychlorinated biphenyls and dibenzofurans due to ingestion of contaminated cooking oil. This event was called Yucheng, "oil-syndrome" in Chinese. We followed the exposed persons and compared their cause-specific mortality wi...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2012.09.003
更新日期:2013-01-01 00:00:00
abstract::Air pollution caused by particulate matter (PM) has become a serious issue, and significant research has focused on managing large stationary emission sources, i.e., the primary sources of PM. Currently, the U.S. Environmental Protection Agency (EPA) Method 201A and ISO 23210 are predominantly employed to measure the ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110507
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:Dairy working increases the prevalence of lower airway respiratory diseases, especially COPD and asthma. Epidemiological studies have reported that chronic inhalation of organic dusts released during specific daily tasks could represent a major risk factor for development of these pathologies in dairy worker...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.07.025
更新日期:2017-10-01 00:00:00
abstract::This study is based on the analysis of a set of industrial sectors (coal processing, wood processing, transport, oil, and water treatment) in order to identify the amount and type of combustible waste suitable for incineration. The main ignition and combustion parameters of these wastes have been experimentally obtain...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108559
更新日期:2019-09-01 00:00:00
abstract::An attempt has been made to study the biochemical properties of lung alkaline phosphatase so that it may serve as a model for measuring the toxicity of air pollutants, especially metals. Lung was shown to be a better source of this enzyme in comparison to other organs in rats. The optimum pH, metal requirements, subst...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(87)80053-1
更新日期:1987-06-01 00:00:00
abstract::In the past two decades, epidemiological studies have shown that air pollution is one of the causes of morbidity and mortality. In this study the effect of PM10, PM2.5, NO2, SO2 and O3 pollutants on human health among the inhabitants of Mashhad has been evaluated. To evaluate the health effects due to air pollution, t...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2016.07.039
更新日期:2016-11-01 00:00:00
abstract::Various materials have been investigated for the adsorptive removal of volatile organic compounds (VOCs, such as benzene). However, most materials proposed for the adsorptive removal of gaseous benzene (and other VOCs) perform relatively poorly (e.g., an impractically low-service 10% breakthrough volume [BTV10] at < 1...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.109043
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Healthcare workers (HCWs) are highly exposed to SARS-CoV-2 infection given their specific tasks. The IgG-IgM serological assay has demonstrated good accuracy in early detection in symptomatic patients, but its role in the diagnosis of asymptomatic patients is uncertain. The aim of our study was to assess IgM...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2021.110793
更新日期:2021-01-25 00:00:00
abstract:BACKGROUND:Human biomonitoring (HBM) data is increasingly being compared to risk-based screening values to assess human health risk. However, as screening values have not been established for assessing biomarker concentrations of organophosphate (OP) pesticide metabolites, there are few studies using HBM data on urinar...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108739
更新日期:2020-03-01 00:00:00
abstract::The fractionation of natural organic matter (NOM) and its impact on the binding of quinolones to mineral surfaces and transport behavior under flow-through conditions have been scarcely investigated. In this study, the sorption and transport of a widely used quinolone antibiotic, Nalidixic acid (NA), were investigated...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110187
更新日期:2020-12-01 00:00:00