Urinary phthalate metabolites are associated with insulin resistance in obese subjects.

Abstract:

:Phthalates are potentially involved in the development of type 2 diabetes mellitus. In a cohort of 123 obese subjects, 10 phthalate metabolites were analyzed. An oral glucose tolerance test was performed and various estimates of insulin resistance and beta-cell function were calculated. After adjustment for age, physical activity level, smoking behavior, medication use and body mass index, several phthalate metabolites were linked to markers of glucose tolerance and insulin resistance.

journal_name

Environ Res

journal_title

Environmental research

authors

Dirinck E,Dirtu AC,Geens T,Covaci A,Van Gaal L,Jorens PG

doi

10.1016/j.envres.2015.01.010

subject

Has Abstract

pub_date

2015-02-01 00:00:00

pages

419-23

eissn

0013-9351

issn

1096-0953

pii

S0013-9351(15)00011-0

journal_volume

137

pub_type

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