Abstract:
:Background "En face" optical coherence tomography (OCT) is an imaging technique with optic sections parallel to the retinal pigment epithelium (RPE). This study aims to define the use of this technique in the evaluation of small pigmented choroidal tumors. Patients and Methods Investigation of 27 small pigmented choroidal tumors with "en face" OCT. Following manual segmentation, the optic sections performed with a spectral domain OCT at 30, 80 and 130 µ under the RPE were selected for morphological and statistical analysis. Results Internal tumor reflectance is variable (hyper-, iso-, or hypo-reflective), with a uniform or a bull's eye appearance. The reflectance becomes progressively lower towards the centre of the tumor. The margins of the pigmented tumors appear similar or less extensive than ophthalmoscopically. Peritumoral vascularization appears distinct from the 80 µ section downwards. Conclusions On "en face" OCT, small pigmented choroidal tumors present with a uniform or bull's eye internal reflectance, and are of variable intensity relative to the surrounding choroid. Their margins can appear more restrained than those on colour fundus photography.
journal_name
Klin Monbl Augenheilkdjournal_title
Klinische Monatsblatter fur Augenheilkundeauthors
Cotting-Bodmer S,Zografos L,Schalenbourg Adoi
10.1055/s-0042-123172subject
Has Abstractpub_date
2017-04-01 00:00:00pages
597-599issue
4eissn
0023-2165issn
1439-3999journal_volume
234pub_type
杂志文章abstract:BACKGROUND:Data from real-life studies on neovascular AMD (nvAMD) generally fall significantly behind respective data from interventional prospective trials. This can be attributed at least partially to differences in patient cohorts concerning both stages of AMD (including consecutive scarring or atrophy), as well as ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0041-107672
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:The purpose of this study was to assess the vasoconstrictor effect of the prostaglandin F2 alpha analog latanoprost in isolated porcine ciliary arteries. MATERIAL AND METHODS:With a myograph system to measure isometric forces, porcine ciliary arteries were exposed, in a cumulative manner, to increasing concent...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2001-15904
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:The ICG filling is supposed to be faster than Fluorescein filling. Interestingly the filling characteristics of these dyes were never correlated directly using precise quantitative methods. Since ICG and Fluorescein are injected as a mixture, the simultaneous 2-channel angiography provides a suitable method ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2000-10558
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:In the light of studies in children which showed no significant changes concerning anterior chamber depth, central corneal thickness and chamber angle width after eye muscle surgery, the aim of this study was to evaluate such changes in adults by means of optical coherence tomography. PATIENTS AND METHODS:U...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0029-1245748
更新日期:2010-10-01 00:00:00
abstract::In anophthalmos the forces which stimulate development and growth of the bony orbit are absent. As a result these cases have not only a tiny socket but also an underdeveloped bony orbit, which cannot retain an artificial eye. The small conjunctival sac and bony orbit can be mechanically enlarged by means of Hema socke...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050502
更新日期:1987-09-01 00:00:00
abstract::In case of keratoconus the epithelial cells are also participating in the pathological processes. Their activity of producing basal membrane is increased. In the stroma four cell types are found; two of them are normal elements. The origin of the two pathological forms is unknown. They may represent as well vagrant ce...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-03-01 00:00:00
abstract:BACKGROUND:Non-neovascular age-related macular degeneration (AMD) is not yet treatable. This article summarises current clinical research approaches. The reasons for the current lack of success are analysed. METHODS:Literature and databank search. RESULTS:The number of therapeutic approaches and mechanisms is limited...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-0914-3183
更新日期:2019-09-01 00:00:00
abstract::The microsurgical processing of longterm preserved tissue is still a problem for lamellar and perforating keratoplasties. Advantages of donor tissue cut with rotortrephines versus manual trephines are presented. Optimal possibilities of examination and storage of donor tissue are explained. A lamellar microkeratome, a...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2008-1045717
更新日期:1992-02-01 00:00:00
abstract::We report on a 46-year old white male with Norrie disease. In the right eye he had a keratotorus with non vascularized corneal scars and mature cataract. After penetrating keratoplasty a pseudoglioma with irreversible total retinal detachment was found. The left eye had phthisis bulbi with corneal pannus and band kera...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1046058
更新日期:1991-08-01 00:00:00
abstract::Over a period of 4 months the authors observed 240 outpatients with 302 "red eyes." Oculogenital strains of Chlamydia trachomatis were diagnosed in 12.5% of these cases. Bacterial monoinfections were found in 13.9%, coinfections in 63.9%. The remaining 9.7% included Candida sp. (4%) and Herpes I (1.4%) infections, whi...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1054593
更新日期:1984-09-01 00:00:00
abstract::Out of 1300 eyes enucleated between 1966-1974, 300 subsequently revealed histologically-proved malignant melanomas of the uvea. In 264 cases the clinical diagnosis was correctly made. In 36 cases the i.o. malignant melanomas were clinically unsuspected. The incorrect clinical diagnoses included: secondary glaucoma (30...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-03-01 00:00:00
abstract:BACKGROUND:Vitamin A deficiency is a leading cause of blindness in childhood in the developing countries. In developed countries xerophthalmia occurs mainly as secondary hypovitaminosis due to malabsorption in chronic alcoholism or intestinal disorders. PATIENT AND METHODS:A 24-year-old female patient complained of ni...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1034956
更新日期:1998-08-01 00:00:00
abstract::The biological significance of autophagy in the metabolism of visual cells is discussed. In the process of autophagy, parts of the cytoplasm including cell organelles are surrounded by membranes. This formation is called an autophagic vacuole. Then, the contents of the vacuole are degraded by enzymes. Autophagy is a w...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-09-01 00:00:00
abstract::The action of some drugs on the eye may lead to the occurrence of unforeseen ocular and extraocular reactions. Vincaleukoblastin (Velbe) provokes serious corneal lesions with a healing time of two weeks and a half. The local application of Neo-Synephrine eye drops (10%) and Mydrial-Atropine ointment may lead in the ca...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-07-01 00:00:00
abstract:BACKGROUND:Previous studies have demonstrated, in the cat, a vasodilatation of retinal vessels in response to neuronal activity induced by diffuse luminance flicker. The aim of this study was to determine whether a similar diameter variation is detectable in humans. MATERIALS AND METHODS:Nine normal subjects were expo...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1034897
更新日期:1998-05-01 00:00:00
abstract::The authors investigated 7 children with developmental anomalies of the optic disc. In all cases a typical pattern of hypoplasia was observed. In all patients was found a very marked impairment of visual acuity or even blindness of the affected eye with most frequently squint and nystagmus. Besides ophthalmological in...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-08-01 00:00:00
abstract::Epibulbar osteomas are benign tumors which are usually present at birth. Up to now 39 cases have been described in the literature. In the last three years 4 further cases have been found in the Freiburg, Hamburg, Marburg, and Munich University Eye Clinics. Epibulbar osteomas probably occur more often than is generally...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057467
更新日期:1980-03-01 00:00:00
abstract::Thirty-six patients with postoperative microstrabismus (24 of them without or with only a slight amblyopia, 12 with severe unilateral amblyopia) and three control groups (normal binocular, long-term monocular, and inexperienced monocular subjects) were tested by their ability to hit 14 vertical sticks set in varied po...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050933
更新日期:1985-05-01 00:00:00
abstract:BACKGROUND:Low-dose oral contraceptives can still cause thromboembolic disorders with serious neurologic or ocular disabilities. PATIENT:A 22-year-old woman having used oral contraceptives for several months noticed sudden painless visual loss in her left eye. One tablet of her contraceptive contained ethinylestradiol...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0031-1273197
更新日期:2011-08-01 00:00:00
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journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0033-1350912
更新日期:2013-10-01 00:00:00
abstract::The results of campimetric investigations performed in 127 eyes (83 patients) are presented. The vertical diameter of the blind spot and intraocular pressure were measured several times before and after oral intake of a dose of glycerol combined with ascorbic acid. The tonometric value obtained when the blind spot is ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1055032
更新日期:1982-02-01 00:00:00
abstract::Whereas by far not all properties of the crystalline lens can be realized with an artifical intraocular lens, maximal stability of such a device is its most important feature. The latter can be achieved by the adherence of the lens to the capsular membrane, left behind after extra-capsular cataract extraction. In this...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-06-01 00:00:00
abstract:BACKGROUND:The healing process of corneal defects requires functioning limbus stem cells. Their loss will lead to secondary wound healing problems. Stem cell research offers new treatment options. MATERIAL AND METHODS:A Medline search of the U. S. National Library of Medicine was carried out. RESULTS:The autologous l...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0028-1109472
更新日期:2009-07-01 00:00:00
abstract:PURPOSE:To analyse the impact of cataract surgery after filtering operation on the intraocular pressure (IOP) due to primary open angle glaucoma (pOAG) versus secondary open angle glaucoma in pseudoexfoliation syndrome (PEX). The regulation of IOP was evaluated on the basis of criteria of advanced glaucoma intervention...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2002-26725
更新日期:2002-03-01 00:00:00
abstract::In the EU more than 70 % of national law has already been replaced by EU law. Medical doctors are mostly not informed, how these EU-laws will pass. Many directives, regulations and decisions are important for medical doctors. A characterization of the EU- institutions is represented. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2005-858749
更新日期:2005-11-01 00:00:00
abstract::Endophthalmitis after penetrating keratoplasty is rare but more frequently observed than after other intraocular procedures. The main source may be a contaminated donor cornea. This survey reviews current concepts of donor globe decontamination and avoidance of infection during preservation. Basically, we suggest the ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2008-1035268
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND:The treatment of therapy-resistant secondary glaucoma with cyclodestructive approaches may give rise to unsatisfactory intraocular pressure results, leading to phthisis. A final option may be the implantation of an external glaucoma drainage system (GDS). A consecutive positioning of the drainage system unde...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:10.1055/s-2007-963181
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:Malignant melanoma of the choroid is the most common ocular primary malignancy, but is still a rare tumour. The occurrence of bilateral uveal melanoma is exceedingly rare. The probability of any one individual developing bilateral melanoma is estimated to be 1 to 50 million. MATERIALS AND METHODS:A retrospe...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2007-963519
更新日期:2007-10-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the duration of the preoperative examination and patient comfort in measurements with an Image Guided System (Verion, Alcon), which is used for the calculation and intraoperative alignment of toric intraocular lenses, in comparison to established keratometry devices. PATIE...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0042-105566
更新日期:2016-08-01 00:00:00
abstract::A short summary of the characteristics of speaking, reading and writing is given, followed by the respective anatomical, physiological and neuropsychological counterparts, which are to be described as the "Hör-Denk-Sprech-Seh-Schreib-Organismus" (H-D-S-S-SCH-O). Various disorders occurring in the H-D-S-S-SCH-O as well...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045842
更新日期:1992-05-01 00:00:00