Abstract:
BACKGROUND:The treatment of therapy-resistant secondary glaucoma with cyclodestructive approaches may give rise to unsatisfactory intraocular pressure results, leading to phthisis. A final option may be the implantation of an external glaucoma drainage system (GDS). A consecutive positioning of the drainage system under the conjunctiva and implantation of the drainage tube into the anterior chamber, may result in an uncontrolled reduced of intraocular pressure leading to intraocular haemorrhages into the anterior chamber or vitreous cavity. In particular, expulsive haemorrhages are feared as deleterious complication. PATIENTS AND METHODS:15 patients (15 eyes) with secondary glaucoma received a GDS. All patients were previously unsuccessfully treated by numerous approaches (mean 2.7 times). The mean preoperative intraocular pressure was 37 mmHg (range: 22 to 55 mmHg). We performed a sequential approach: during the first operation we implanted and fixed the resorption site of a Molteno GDS onto the sclera close to the equator in the superotemporal quadrant. After an inflammation-free interval of 2 - 3 weeks we placed the drainage tube into the anterior chamber. The average postoperative follow-up period was 20.5 months (range: 3 to 62 months). RESULTS:The implantation of the GDS using a sequential approach was well tolerated by all patients. While 14 out of 15 eyes achieved an IOP of 15 mmHg (range: 12 to 18 mmHg), 2 of them still required additional topical glaucoma treatment. An unsatisfactory IOP regulation was observed in only one eye although a revision surgery was performed postoperatively. Four eyes developed a light anterior chamber haemorrhage that resorbed without serious complications within 3 weeks. A choroidal effusion in one eye was treated by an anterior chamber injection of a viscoelastic gel. CONCLUSION:The potential disadvantage of the GDS can be almost completely avoided using a sequential approach. The implant heals well in the subtenon space during the first postoperative week, thus preventing an overfiltration of anterior chamber fluid. Our positive results show that the GDS is an important treatment option in selected patients.
journal_name
Klin Monbl Augenheilkdjournal_title
Klinische Monatsblatter fur Augenheilkundeauthors
Schmidt JC,Meyer CH,Hörle Sdoi
10.1055/s-2007-963181subject
Has Abstractpub_date
2007-08-01 00:00:00pages
641-6issue
8eissn
0023-2165issn
1439-3999journal_volume
224pub_type
临床试验,杂志文章abstract:BACKGROUND:TINU syndrome probably is a frequently overlooked disease where uveitis occurs in association with acute tubulointerstitial nephritis. Diagnostic criteria have been published recently. PATIENTS AND METHODS:In this retrospective case series the charts of four consecutive patients with TINU syndrome (follow-u...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2002-33583
更新日期:2002-07-01 00:00:00
abstract::Out of 1300 eyes enucleated between 1966-1974, 300 subsequently revealed histologically-proved malignant melanomas of the uvea. In 264 cases the clinical diagnosis was correctly made. In 36 cases the i.o. malignant melanomas were clinically unsuspected. The incorrect clinical diagnoses included: secondary glaucoma (30...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-03-01 00:00:00
abstract::83 eyes underwent a re-examination 3-7 years after trabeculotomy. By surgery alone the diurnal curve in 58 out of 74 eyes (78 percent) was regulated. In the majority of the other eyes additional medication controlled the i.o. pressure. There was no secondary cataract or other late complication. In 5 eyes there was a m...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:To investigate the structural basis for functional deficits in infantile strabismus we used a neuroanatomic tracer and a histochemical label to examine the primary visual cortex (area V1) of adult esotropic macaque monkeys. ANIMALS AND METHODS:The animals had developed natural esotropia in the first months ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035162
更新日期:1996-01-01 00:00:00
abstract::5 cases of intraocular Toxocara canis solitary granuloma are demonstrated. The coincidence of two different aspects of a disease: pseudocoloboma of the macula (toxoplasmosis) in the right and a toxocara solitary granuloma in the left eye of the same patient (case 5) perhaps will furnish proof possibility of foetal inf...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-08-01 00:00:00
abstract::There are multiple possible intraocular manifestations in patients with systemic neoplasms. At first line there are uveal, retinal and vitreous metastases from carcinomas, melanomas and lymphomas. In patients with von Hippel Lindau syndrome or familiar adenomatous polyposis coli (FAP), Gardner or Turcot syndromes, fun...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0031-1273474
更新日期:2011-07-01 00:00:00
abstract::The authors investigated the wound closure of conjunctival wounds with fibrin adhesive as compared to a suture technique in rabbits. Similarly, the fixation of a transplant of lyophilized dura mater on the sclera by fibrin adhesive was also compared with a suture technique. Both clinically and histologically, there we...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057252
更新日期:1981-07-01 00:00:00
abstract:PURPOSE:Laser Doppler measurements performed immediately after the transition from dark adaptation (DA) to light led to the hypothesis that retinal blood flow, Fret, is increased during DA, but the use of visible lasers had prevented measurements during DA. Our aim was to test this hypothesis by measuring Fret during a...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2000-10990
更新日期:2000-05-01 00:00:00
abstract:PURPOSE:In 40% retinoblastoma (Rb) results from a hereditary mutation of the Rb susceptibility gene (RB1). In this study, we tested the usefulness of intragenic DNA analysis for ophthalmologic follow-up in affected families. METHODS:Molecular analysis was performed on 103 DNA samples of 15 Rb families. We used 7 intra...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035456
更新日期:1995-05-01 00:00:00
abstract::Using mobile OCT equipment and remote ophthalmological diagnosis of n = 1538 diabetics in 17 diabetes practices in Germany, we found diabetic macular edema in 10.1% of the patients and retinal bleedings or microaneurysms in 15.6%. In 1.62% of the diabetics examined, the size of the edema was > 0.4 mm², in 7% the retin...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-1194-5211
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:The postoperative clinical course after penetrating keratoplasty and trephination in free form using a guided excimer laser beam has been published before. Here the findings of light-microscopy comparing corneal wound healing after experimental penetrating keratoplasty after laser trephination and after conv...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 评论,杂志文章
doi:10.1055/s-2006-927097
更新日期:2006-12-01 00:00:00
abstract:PURPOSE:An evaluation of the visual and refractive results was undertaken one year after implantation of a trifocal diffractive toric intraocular lens (IOL) during cataract surgery. METHODS:In a prospective study patients with a calculated postoperative corneal astigmatism of ≥ 0.75 D received a diffractive trifocal t...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:10.1055/s-0041-103335
更新日期:2015-08-01 00:00:00
abstract::A Study is described of a family in which four children of the same generation died during early childhood; three of them had an obvious hydrocephalus. Two of the latter could be examined clinically, and their eyes removed for pathology. One of them presented clinically bilateral leucocoria; histology showed a total d...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-04-01 00:00:00
abstract::Iatrogenic damage to the orbital fascial system during strabismus surgery may lead to adherences with resulting problems of motility. To prevent new adherences in revisional surgery, several materials were tried, with varying degrees of success. The authors tested Polyglactin 910, popular as a suture material in strab...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050257
更新日期:1988-09-01 00:00:00
abstract:PURPOSE:Corneal ulcer is a very rare clinical manifestation in hereditary familial amyloidosis of the Portuguese type, from which only one case has been reported previously. The case of a 35-year-old man illustrates the diagnostic findings and the difficulties encountered in understanding the physiopathology of such a ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035238
更新日期:1996-05-01 00:00:00
abstract::The present paper communicates clinical and pathohistologic findings in a case of carcinoma in situ of the conjunctiva (Bowen's disease) with a five-year course. Initially, there are clinical similarities between Bowen's disease and Mooren's ulcer; the diagnosis can be established on the basis of the histologic findin...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1987-10-01 00:00:00
abstract::Within a period of 14 months 73 patients with idiopathic blepharospasm which could not be treated satisfactorily by any other form of therapy were treated by injections of botulin toxin. In 55 cases the follow-up period was sufficiently long to permit an evaluation. Thirty-five patients were temporarily completely fre...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050804
更新日期:1986-10-01 00:00:00
abstract::Report on a catamnestic study which attempted to follow up patients who had undergone successful surgery for retinal detachment. A striking finding was that, even today, the vast majority of doctors discourage strenuous physical activity and sport. One of the reasons for this seems to be the discussion concerning the ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057344
更新日期:1981-12-01 00:00:00
abstract:PURPOSE:Sturge-Weber syndrome is a rare congenital disorder consisting of cutaneous, leptomeningeal and ocular vascular malformations. Glaucoma occurs in 30-70 % of patients. Treatment is challenging due to a high risk of severe complications such as expulsive haemorrhage, massive choroidal effusion and serous retinal ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
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更新日期:2012-10-01 00:00:00
abstract::Description of an aspect of a disease characterized by marked retinal venous anastomotic vessels in a 69-year-old man. There is no recognition of blindness of patients left eye and a declared trauma of war. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1977-05-01 00:00:00
abstract::ERG and EOG were performed in three male patients deriving from two no related families and who had vitreo-retinal degeneration including macula area. The EOG was below normal and ERG-potentials particularly b-waves reduced. The finding although of interest are not pathognomically significant. Therefore the diagnosis ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract:BACKGROUND:Proliferative retinopathy is an important cause of vision loss in diabetic patients. Incomplete panretinal photocoagulation (PRP) can lead to recurrent proliferation of new vessels. PATIENTS AND METHODS:We retrospectively analysed the outcome of patients with high risk proliferative diabetic retinopathy (PD...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,随机对照试验
doi:10.1055/s-0035-1545795
更新日期:2015-04-01 00:00:00
abstract::Conjunctivitis is a frequent disease mostly caused by infections. In the case of a single-sided manifestation and additional resistance to anti-infective therapy a widespread differential diagnosis has to be considered. The case report of a 41-year-old patient suffering from unilateral persistent conjunctivitis is pre...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1027457
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:Most reports on transscleral suture fixation of posterior chamber lenses (PCL) do not mention the principal difficulty that the surgeon has no valid information which structures were perforated by the needle and where he happened to fix the PCL loops. To know this exactly is a "conditio sine qua non". Withou...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045599
更新日期:1993-04-01 00:00:00
abstract::Examinations of hormone levels in blind persons compared with almost blind and people with normal vision and hormone evaluation with increased artificial light exposure show a definite stimulating effect of light on the human hormonal balance. The effect of light is mediated by an intact perception of light by the eye...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1977-07-01 00:00:00
abstract:BACKGROUND:Morbus Morbihan is a rare complication of rosacea, consisting of a persistent lymphoedema of the upper part of the face. It has typically a chronic course, unspecific histopathological findings and an extreme refractoriness to therapy. PATIENTS AND METHODS:Between February 2008 and January 2010, 5 patients ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0029-1245960
更新日期:2011-01-01 00:00:00
abstract::Botulinum toxin is recognised as the gold standard for the treatment of essential blepharospasm and hemifacial spasm, which is similar in effect in synkinesis after facial nerve palsy. The injection intervals can be adjusted according to the patients' needs and be shortened for up to six weeks in cases of eyelid cramp...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0042-122339
更新日期:2018-06-01 00:00:00
abstract::Among the 185 retinoblastoma patients seen at the Lausanne Retinoblastoma Clinic from 1963-1993, 24 (14%) first presented with another sign than classical leukocoria (60.5%) or strabismus (21.5%). Most of these atypical signs were related to inflammatory complications of unrecognized retinoblastoma; they consisted of ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035546
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND:Myelodysplastic syndrome is a clonal disease of the hematopoetic system characterized by insufficiency of affected bone marrow cell lines. After long-term course of myelodysplastic syndrome an acceleration towards acute myeloic leukemia is a frequent finding. Involvement of the eye is a well known phenomenon...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1034944
更新日期:1998-07-01 00:00:00
abstract:BACKGROUND:Several enzyme defects of the galactose pathway may lead to cataract formation. We report on a family with familiar cataract. PATIENTS:A 2-year-old Turkish girl (daughter of first cousins) presented with dense cortical and subcapsular opacifications and mature cataract respectively. Bilateral phacectomy, pl...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1034710
更新日期:1999-10-01 00:00:00