Abstract：
BACKGROUND:Morbus Morbihan is a rare complication of rosacea, consisting of a persistent lymphoedema of the upper part of the face. It has typically a chronic course, unspecific histopathological findings and an extreme refractoriness to therapy. PATIENTS AND METHODS:Between February 2008 and January 2010, 5 patients with Morbus Morbihan were observed at the Department of Ophthalmology of the University Medical Centre Mainz. In the present cohort study, we describe the clinical, laboratory and histological findings that led to the diagnosis. The course of the affection and the results of different therapeutic options are also reported. RESULTS:Each patient underwent a complete ophthalmological examination, as well as general and dermatological consultations. All patients showed facial skin alterations typical for rosacea. 4 out of 5 subjects underwent a lid biopsy to confirm the diagnosis of Morbus Morbihan, one patient refused it. Initial treatment consisted of various systemic and local medical therapies, however, with poor success. One patient had intravenous therapy with corticosteroids elsewhere with no effect. We treated 3 cases with intralesional triamcinolone injections with good results. 2 patients underwent upper lid blepharoplasty. Results of surgery remained stable also due to manual lymph drainage and intralesional injections of triamcinolon. No complications or side effects were seen in patients treated with triamcinolone. CONCLUSIONS:Morbus Morbihan can be diagnosed only after excluding other conditions leading to chronic lid swelling. In our series, good results were achieved with intralesional injection of triamcinolone. Surgery also led to relevant improvements for a long period (13 months), with some adjuvant therapy. The treatment of chronic eyelid oedema associated with rosacea remains a challenge for the ophthalmologist and the oculoplastic surgeon.
journal_name
Klin Monbl Augenheilkdjournal_title
Klinische Monatsblatter fur Augenheilkundeauthors
Renieri G,Brochhausen C,Pfeiffer N,Pitz Sdoi
10.1055/s-0029-1245960subject
Has Abstractpub_date
2011-01-01 00:00:00pages
19-24issue
1eissn
0023-2165issn
1439-3999journal_volume
228pub_type
杂志文章abstract：:During the last years electrophysiology in ophthalmology has been facilitated to a big extent by computerized methods. Thus it has become a suitable method for an increasing number of relevant diagnostic problems. To make comparisons between test results of different diagnostic places easier an international standard ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章,评审
doi：10.1055/s-2008-1045575
更新日期：1993-02-01 00:00:00
abstract：:Für die (Früh-)Diagnose einer Glaukomerkrankung ist die Beurteilung der Papille von entscheidender Bedeutung. Das Spektrum von High-Tech-Geräten zur Papillenbeurteilung hat sich in den letzten Jahren erweitert und die Anwendung ist in der klinischen Praxis angekommen 1. Voraussetzung für die sinnvolle Anwendung und In...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-0033-1358179
更新日期：2015-09-01 00:00:00
abstract：:On two female patients it was shown that intoxication by sedatives containing part bromecarbamide may result in various ocular diseases. The two patients complained of a sudden inexplicable deterioration of vision; semi-dilated slow-responding pupils were diagnosed. Only in one case could a sudden vertical nystagmus b...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：BACKGROUND:A major focus of our study was to determine the value of postoperative intraocular pressure (IOP) in predicting the outcome of trabeculectomy (TE). PATIENTS AND METHODS:The medical charts of 547 patients undergoing glaucoma filtering surgery at the Department of Ophthalmology of the University of Cologne fr...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2000-10376
更新日期：2000-07-01 00:00:00
abstract：:A 67-year-old woman patient presented with protrusion of the right globe of unknown origin. Computer tomography revealed a probably benign space-occupying lesion (osteoma) originating in the orbital wing portion of the sphenoidal bone and extending to the orbital roof of the frontal bone. ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1057477
更新日期：1980-03-01 00:00:00
abstract：:We present two further cases of choroiditis geographica. One of them we were able to follow up for two years. This allowed us to observe from the beginning the eye which was not at first involved. Weeks before the first lesions were visible, alterations of the EOG appeared. In the other case both eyes were already inv...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1984-10-01 00:00:00
abstract：:In 40.8% of 169 eyes affected with diabetic preretinopathy (verified by fluorescein angiography) arteriovenous shunt vessels were found. These vessels occur with significant prevalence in eyes with areas of retinal capillary occlusions, and in cases with diabetes of long duration. There is strong evidence that AV shun...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1057587
更新日期：1980-06-01 00:00:00
abstract：:The clinical application of TV fluorescein angiography with subsequent image analysis as performed on a patient with familial Mediterranean fever (FMF), who was suffering from an arterial branch occlusion, is discussed. In addition, the diagnostic relevance of rheologic parameters to the diagnostic evaluation of retin...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1050888
更新日期：1985-02-01 00:00:00
abstract：BACKGROUND:Using biomicroscopy the evidence of deposits of silicone oil in the anterior segment after vitrectomy is limited. We examined the anterior segment by high resolution ultrasound to verify the possibility to identify silicone oil. MATERIALS AND METHODS:Ten patients treated by vitrectomy with instillation of s...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2002-36327
更新日期：2002-11-01 00:00:00
abstract：:In a randomized and controlled study (already published) the efficacy and safety of Pindolol eye drops 1% were compared with Timolol eye drops 0.5% in the treatment of open-angle glaucoma over a period of 6 months. With the exception of some allergic reactions there was no difference between the two with regard to IOP...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1050872
更新日期：1985-01-01 00:00:00
abstract：:The authors report on 120 patients who underwent iridencleisis (155 eyes). Of these, 36 had open-angle glaucoma, 26 congestive glaucoma and 54 were suffering from acute glaucoma of long standing. Two patients had exfoliation syndrome and two, secondary glaucoma. The kind of filtration bleb, postoperative complications...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1054765
更新日期：1983-04-01 00:00:00
abstract：:The beta-blocker Metipranolol is discussed with reference to a pilot study and a double-blind study. It was found to be remarkably effective in lowering intraocular pressure. No statistically significant difference was found between Metipranolol and Timolol with regard to their effect on intraocular pressure and blood...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 临床试验,杂志文章
doi：10.1055/s-2008-1054859
更新日期：1983-06-01 00:00:00
abstract：:Forty eyes were studied in order to establish the relative function of the upper and lower lacrimal ducts. Following artificial occlusion first of the upper and then of the lower lacrimal ducts. Schirmer's No. 1 test was performed. The wetting of the test strips was used as an indirect measure of tear discharge. Highe...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1054425
更新日期：1984-02-01 00:00:00
abstract：BACKGROUND:Corneal cross-linking (CXL) with riboflavin is being used more frequently for the treatment of therapy-resistant microbial keratitis, since increasing drug resistance and specific pathogens, e.g. contact lens-associated Acanthamoeba, make this therapy appear as an attractive option to avoid a keratoplasty à ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-0034-1368535
更新日期：2014-06-01 00:00:00
abstract：INTRODUCTION:The course of the recovery phase after general anaesthesia, during which consciousness and pain gradually return, is essentially determined by the choice of anaesthetic drug, and its total dose or duration of application. This phase is often complicated by more or less severe agitation, especially in child...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章,随机对照试验
doi：10.1055/a-1260-3023
更新日期：2020-10-01 00:00:00
abstract：:The 30-prism-test is a relatively quick and simple method for many-sided testing binocular behaviour in near distance in patients with reading difficulties and asthenopic symptoms, respecting well known and assumed causes of the disturbances. Therefore indications for treatment are given. ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1035556
更新日期：1994-05-01 00:00:00
abstract：:Extensive experimental research proved that the healing of lens capsule wounds can be supported effectively by application of a fibrin tissue adhesive. The result is a circumscribed scar in an otherwise clear lens. The clinical application of the method was successful as well. Preliminary results have been published a...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1054911
更新日期：1983-10-01 00:00:00
abstract：:In 21 patients with macular hole and retinal detachment a macular buckling procedure was performed including diathermic or cryogenic coagulation. An absorbable fibrin sponge (Fibrospum) was used as a new buckling material, which needs not to be sutured to the sclera at the posterior pole. In comparison to other proced...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1977-08-01 00:00:00
abstract：:Arteriovenous malformation is a rare vascular disease of the orbit that has to be differentiated from arteriovenous fistulas (e.g., of the carotid sinus), arterial aneurysms, the varices and the angiomas. It develops in the presence of an underlying constitutional maldifferentiation of the vascular bed but usually onl...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1046343
更新日期：1989-02-01 00:00:00
abstract：BACKGROUND:There is no exact knowledge concerning blinding diseases in Germany. Purpose of this study was to investigate the changes of diseases leading to new blindness in Baden (Southern Germany). METHODS:We evaluated the ophthalmological diseases leading to blindness in Baden from the applications presented to the ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2004-812724
更新日期：2004-02-01 00:00:00
abstract：BACKGROUND:In the last years, new findings from the research on pain diseases and the enhancement of therapeutic options have drastically changed the treatment of postherpetic neuralgia (PHN). This disease, belonging to the neuropathic pain syndromes, needs an adequate pain therapy at an early stage to prevent pain chr...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章,评审
doi：10.1055/s-0029-1245273
更新日期：2010-05-01 00:00:00
abstract：:An early diagnosis, differential diagnosis and possible decision about therapeutic interventions has considerable consequences for the personal and social life of patients affected with inherited retinal dystrophies (IRD). For the ophthalmologist, the clinical heterogeneity interferes with a simple diagnostic approach...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章,评审
doi：10.1055/a-1118-3705
更新日期：2020-03-01 00:00:00
abstract：:In an attempt to determine the accuracy of ultrasound biometry, the spherical equivalent of the refraction obtained after ECCE and implantation of a posterior chamber IOL in 1663 patients was compared to the desired refraction determined prior to surgery. Follow up time was 21 months on the average. In only 7.4% of th...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1046055
更新日期：1991-08-01 00:00:00
abstract：BACKGROUND:Computer-controlled video keratoscopy is being employed ever more frequently and for various indications. PATIENTS:We have studied the effects of high-viscosity and low-viscosity tear substitutes on the corneal topography, one and five minutes after application to 14 normal eyes of 7 subjects, and compared ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1035260
更新日期：1996-06-01 00:00:00
abstract：:Biological, rather then purely technical approach seems to be very essential to ensure better results in alloplasty of the cornea. The diseased corneal tissue (especially, after corneal burns) usually fails to accept a keratoprosthesis permanently. The cornea must, therefore, be biologically reconstructed by transplan...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1976-05-01 00:00:00
abstract：BACKGROUND:Cysticercosis is one of the two infections caused by Taenia solium. It is endemic in areas with poor hygienic standards. In western countries the patients history of previous living or travelling in endemic areas is important. Neurocysticercosis is a manifestation with single or multiple ocular, orbital or c...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1034723
更新日期：1999-11-01 00:00:00
abstract：BACKGROUND:Vitamin A, the fat soluble vitamin, must be supplied orally before resorption in the mucosa of the small intestine and storage in the liver. Vitamin A deficiency can cause alterations in the anterior segment of the eye, from Bitot spots, which are reversible, to irreversible keratomalacia. PATIENTS AND METH...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1045496
更新日期：1994-08-01 00:00:00
abstract：:A patient who had been exposed to toluol for ten years developed acute erythropsia. The examinations leading to the diagnosis and the possible differential diagnosis are discussed. ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1046214
更新日期：1990-05-01 00:00:00
abstract：:The present study consists of light- and electron-microscopic examination of excised cornea in a case of lipid keratopathy (Schnyder) in which a perforating keratoplasty was performed. It demonstrates the deposition of cristalline and non-cristalline substances in the corneal epithelium as well as the anterior half of...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1978-09-01 00:00:00
abstract：OBJECTIVE:Comparison of retinal neovascularizations of the disc (NVD) and elsewhere (NVE) in optical coherence tomography angiography (OCTA) and fluorescein angiography (FA) in patients with proliferative diabetic retinopathy. MATERIALS AND METHODS:15 consecutive patients were included in this study. All patients rece...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/a-0983-2271
更新日期：2019-11-01 00:00:00
