Abstract:
INTRODUCTION:The course of the recovery phase after general anaesthesia, during which consciousness and pain gradually return, is essentially determined by the choice of anaesthetic drug, and its total dose or duration of application. This phase is often complicated by more or less severe agitation, especially in children. In the present study we investigated whether the application of a topical anaesthetic to the conjunctiva at the end of a strabismus operation had a positive effect on the recovery behaviour of the child. PATIENTS/METHODS:This prospective, randomised, blinded study was conducted with 50 healthy, ASA class I or II children, aged 3 to 8 years undergoing their first strabismus operation. Following the surgeon's randomisation two drops of a 0,5% tetracaine-HCl ophthalmic solution were applied to the operated conjunctiva three times at 30-s intervals immediately following wound closure. The postoperative evaluation encompassed heart rate, as well as COMFORT and CHEOPS scores. The first assessment was directly postoperatively with repetitions at 15, 30, 45, 60, 75, 90 and 120 min, as well as on the day after surgery. RESULTS:The CHEOPS scores did not differ significantly between children with or without topical anaesthesia at any time during the observation period. The COMFORT scores revealed a slight, but non-significant analgesic effect at 15 and 30 min. The 60 min score showed the opposite effect, possibly indicating a slight disadvantage of the topical anaesthesia. There were no significant differences with regard to time to first request for additional systemic analgesia, to the total dose of systemic pain medication, or to when the patient was eligible for discharge to the ward. CONCLUSION:The application of topical tetracaine-HCl immediately after wound closure had no positive effects on the course of the postoperative recovery period after strabismus surgery in children. There was no evidence of an effect on pain or emergence agitation. HINTERGRUND:Die Dauer der Aufwachphase nach einer Allgemeinanästhesie, in der Bewusstsein, Kontaktfähigkeit und Schmerzempfinden allmählich wiederkehren, wird im Wesentlichen von der Art, der Dosis und der Applikationsdauer der verwendeten Narkosemittel bestimmt. Diese Phase ist, gerade bei Kindern, häufig von Schmerz und Agitation gekennzeichnet. In der vorliegenden Studie wurde untersucht, ob sich eine unmittelbar am Ende einer Augenmuskeloperation applizierte Oberflächenanästhesie positiv auf das Aufwachverhalten des Kindes auswirkt. PATIENTEN/METHODIK:Eingeschlossen in diese prospektive, randomisierte, verblindete Studie wurden 50 gesunde Kinder der ASA-Klassen I oder II im Alter von 3 bis 8 Jahren, bei denen eine erste Augenmuskeloperation durchgeführt wurde. Randomisiert wurden 3-mal im Abstand von je 30 s 2 Tropfen 0,5% Tetracain-Augentropfen in das/die operierte(n) Auge(n) gegeben. Die postoperative Beurteilung erfolgte anhand von CHEOPS- und COMFORT-Skalen unmittelbar postoperativ sowie nach 15, 30, 45, 60, 75, 90 und 120 min und am Folgetag der Operation. ERGEBNISSE:Die CHEOPS-Scores zeigten über den gesamten Beobachtungszeitraum keine signifikanten Unterschiede. Die COMFORT-Scores wiesen initial (15 und 30 min) auf leicht geringere Schmerzen und Agitation hin (statistisch nicht signifikant). Ab 60 min postoperativ ergaben sich eher stärkere Schmerzen, sodass ab dann ein Nachteil in der Applikation der zusätzlichen Tropfen gesehen werden kann. Es zeigte sich kein signifikanter Unterschied im Hinblick auf den Zeitpunkt der Anforderung oder die Dosis von zusätzlicher systemischer Schmerzmedikation oder bez. der notwendigen Verweildauer im Aufwachraum. SCHLUSSFOLGERUNG:Die zusätzliche Applikation eines Lokalanästhetikums (Tetracain-HCl) unmittelbar postoperativ erbringt keinen positiven Nutzen in Bezug auf die postoperative Aufwachphase nach Augenmuskeloperationen bei Kindern. Eine Reduktion von Schmerzen oder Agitation konnte nicht bewiesen werden.
journal_name
Klin Monbl Augenheilkdjournal_title
Klinische Monatsblatter fur Augenheilkundeauthors
Karstädt N,Crozier TA,Horn M,Naxer S,Schittkowski MPdoi
10.1055/a-1260-3023subject
Has Abstractpub_date
2020-10-01 00:00:00pages
1194-1201issue
10eissn
0023-2165issn
1439-3999journal_volume
237pub_type
杂志文章,随机对照试验abstract::The term glaucoma is used as a melting pot of many different diseases which have in common that the retinal ganglion cells and their axons are damaged. Untreated, apoptosis can be induced causing ganglion cell death which subsequently leads to typical glaucomatous damage at the optic nerve head, scotomas of the visual...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0031-1299246
更新日期:2012-02-01 00:00:00
abstract::The causes of hypo- and hyperchromic heterochromia were analysed in 94 patients. The hypochromic forms were the commonest, especially the Fuchs-Herrenschwandt heterochromia, and heterochromia simplex. Also after degenerative diseases and accidents appears almost exclusively hypochromic heterochromia. Causes of hyperch...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to describe the effectiveness of aflibercept in treatment-naive patients with neovascular age related macular degeneration (nAMD) and the impact of patients' residential distance to the clinic and patients' mobility on therapy in a pro re nata regime. METHODS:A retrospective dataset ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-1008-9357
更新日期:2020-06-01 00:00:00
abstract::The tearing eye (epiphora) is the guiding symptome of nasolacrimal duct obstruction. Depending on the localization of stenosis, mucopurulent lacrimal discharge occurs additionally. These symptoms induce alterations of the optical system and can cause severe complications such as acute phlegmonous dacryocystitis. The g...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-1283-9271
更新日期:2020-11-18 00:00:00
abstract::Prophylactic cryo coagulation is especially suitable when there is cloudy media, e.g. blood in the vitreous body or a cataract which would prevent light or laser coagulation. Cryo lesions applied under ophthalmoscopic control are without complication. The paper reviews the 116 eyes collected in 1971 and augments it wi...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-06-01 00:00:00
abstract:BACKGROUND:About 3-10% of patients suffering from metastatic disease develop metastatic choroidal tumors. In this case report ocular symptoms were the first sign of a systemic malignancy. CASE REPORT:A 65-year old man complained of an increasing painful redness of his left eye. He showed a white mass with 10 mm in thi...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2000-10578
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:Vitamin and trace element deficiencies may cause visual disturbances. Before starting a substitutional therapy, specific investigations should be performed. HISTORY AND SIGNS:We present a kidney-transplanted patient who suffered for 6 months from night blindness. The electroretinography showed a severe decr...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2006-926632
更新日期:2006-05-01 00:00:00
abstract::During his researches on colour-vision Goethe has examined two colour blind students. The reports and the colour tests made by Goethe himself are mostly preserved. Due to the colour confusions in the whole purple zone Goethe decided that the subjects were blue blind. During the 19th century-- however--the supposition ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 传,历史文章,杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract:PURPOSE:To remind of the absolute necessity for early diagnosis in the presence of ocular signs in children giving rise to possible intraocular tumours. METHOD:Based on our own experience of intraocular tumours in children, together with findings from the literature, diagnostic criteria and methods of treatment are pr...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2001-15884
更新日期:2001-05-01 00:00:00
abstract:PURPOSE:The aim of this study was to investigate the vasorelaxing properties of pinacidil (a potassium-channel-opener) in isolated porcine ciliary arteries. METHODS:Isometric contractions of isolated porcine ciliary arteries were measured with a myograph system. The vessels were first precontracted with the thromboxan...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2001-15894
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:The aim of this study was to compare the results of intraocular pressure (IOP) measurements obtained using the pressure phosphene tonometer Proview with those from Goldmann applanation tonometer (GAT) in normal and glaucomatous eyes. PATIENTS AND METHODS:The IOP in 150 eyes of 62 healthy volunteers and 88 p...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2006-927094
更新日期:2006-11-01 00:00:00
abstract:PURPOSE:To heighten the awareness of the medical world to the importance of correct and rapid diagnosis in the presence of leukocoria in the child. METHODS:Starting with the presenting symptom, the authors present the guide lines to follow in a practical manner in order to reach a diagnosis in the principal retinal di...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2008-1034807
更新日期:1999-05-01 00:00:00
abstract:PURPOSE:To assess the safety and efficacy of treatment of macular edema secondary to central retinal vein occlusion (CRVO) with intravitreal bevacizumab. PATIENTS AND METHOD:The ongoing prospective study included 8 consecutive patients (8 eyes) with macular edema secondary to CRVO (6 non ischemic and 2 ischemic), trea...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:10.1055/s-2008-1027258
更新日期:2008-05-01 00:00:00
abstract:PURPOSE:Diabetic retinopathy (DR) is a microvascular disease characterized by capillary dropout and resultant retinal ischemia which then leads to retinal vascular remodeling. Our goal was to assess blood flow velocities in retinal collateral vessels in healthy and diabetic subjects with various stages of DR. METHODS:...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-0861-9675
更新日期:2019-04-01 00:00:00
abstract::This is a rare auto-immune illness with necrosis of cartilages. Palpebral oedema, conjunctivitis, episcleritis, iridocyclitis and proptosis belong to this syndrom. But the cataracts often described are iatrogenic, due to the intense corticotherapy required. A report is given of one personal observation and discussion ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-04-01 00:00:00
abstract::The author presents a set of colored pictures which permits to delimitate 3 kinds of zonular fibers. 1. Short anterior fibers. 2. Short posterior or medial fibers, and 3. long posterior fibers. Describe also 3 irregular rings where the zonular fibers are firmly attached to the hyaloids and vitreous. 1. The Wieger's or...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1977-07-01 00:00:00
abstract::According to the German Social Legal Code I (I. Sozialgesetzbuch, SGB I) the recipient of social benefits is under obligation to submit to medical treatment if such treatment would result in an improvement of his/her condition or in the prevention of further deterioration (section 63 SGB I). In certain situations, lac...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050624
更新日期:1986-03-01 00:00:00
abstract:BACKGROUND:We wanted to analyse and compare the results of our first 100 cases of refractive surgery using the commonly accepted refractive parameters and using more subjective data. MATERIALS AND METHODS:Retrospective analysis of the first 100 consecutive cases of refractive surgery using objective and subjective cri...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1998-05-01 00:00:00
abstract::35 patients were examined for their pseudoaccommodation 6 to 18 months after cataract extraction and implantation of a diffractive multifocal intraocular lens (MIOL). While in 15 patients a MIOL had been implanted in both eyes 20 patients had a MIOL in one eye only. 45 type 3M 815 LE and 5 3M 825 XE lenses were implan...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045554
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:The present study investigates how often a simultaneous fluorescein and indocyanine green (ICG) angiography had therapeutic consequences and if it is useful as a clinical routine diagnostic tool. PATIENTS AND METHODS:502 consecutive simultaneous angiographies in eyes with exudative macular degeneration were...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2005-858011
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND:Long-term follow-up and angiographic findings of serpiginous choroiditis, a chronic disease with recurrences of unknown origin, are reported. PATIENTS AND METHODS:A retrospective analysis of the data of 4 patients with serpiginous choroidopathy, who were treated in the eye clinic of Mainz in the past 10-18 ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2006-926575
更新日期:2006-05-01 00:00:00
abstract::Description of an aspect of a disease characterized by marked retinal venous anastomotic vessels in a 69-year-old man. There is no recognition of blindness of patients left eye and a declared trauma of war. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1977-05-01 00:00:00
abstract:BACKGROUND:The aim of this study is to report the feasibility of one to two weeks delayed reconstruction after eyelid tumor excision. PATIENTS AND METHODS:A retrospective case-series study was designed. Fourteen consecutive outpatients referred to a tertiary referral eye center for eyelid tumor management were enrolle...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0031-1299208
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Computer programmes for visual stimulation may give new impulses to the field of amblyopia treatment by offering an option to shift the apparative visual training into the domestic sphere. Regarding this aspect we report on a placebo controlled study on a newly developed vision training consisting of a backg...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:10.1055/s-2001-14921
更新日期:2001-04-01 00:00:00
abstract::Epibulbar osteomas are benign tumors which are usually present at birth. Up to now 39 cases have been described in the literature. In the last three years 4 further cases have been found in the Freiburg, Hamburg, Marburg, and Munich University Eye Clinics. Epibulbar osteomas probably occur more often than is generally...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057467
更新日期:1980-03-01 00:00:00
abstract::There are three forms of lens dislocation in the posterior segment: intravitreal, prebasal, and intrabasal. The location of the dislocated lens depends on gravity and the condition of the vitreous body. As a rule the dislocated lens lies at the bottom of the vitreous cavity; it may be completely embedded in the vitreo...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050310
更新日期:1988-12-01 00:00:00
abstract::In facial hemiatrophy two different types are known: the progressive acquired type, which is relatively more common, and the rare congenital non progressive form. Two children--both with congenital facial hemiatrophy--are presented, both showed a (horizontally and vertically) smaller lid fissure and antimongoloid conf...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045880
更新日期:1992-08-01 00:00:00
abstract::Cataract surgery is evolving more and more into a refractive procedure with high expectations in terms of visual rehabilitation. Especially patients presenting after previous Excimer laser corneal surgery are used to being independent from glasses. Unfortunately, some of these patients showed unexpected hyperopic surp...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0029-1245594
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Using biomicroscopy the evidence of deposits of silicone oil in the anterior segment after vitrectomy is limited. We examined the anterior segment by high resolution ultrasound to verify the possibility to identify silicone oil. MATERIALS AND METHODS:Ten patients treated by vitrectomy with instillation of s...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2002-36327
更新日期:2002-11-01 00:00:00
abstract::After a discussion of the pathomechanism of frontobasal cranial injury with a consecutive chiasmal lesion and diabetes insipidus due to a fracture of the basis of the skull, a personal observation of bitemporal hemianopia with a transient diabetes insipidus after a frontal motorcycle crash is recorded. A short survey ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-07-01 00:00:00