[Clinically unsuspected malignant melanomas of the posterior uvea (author's transl)].

Abstract:

:Out of 1300 eyes enucleated between 1966-1974, 300 subsequently revealed histologically-proved malignant melanomas of the uvea. In 264 cases the clinical diagnosis was correctly made. In 36 cases the i.o. malignant melanomas were clinically unsuspected. The incorrect clinical diagnoses included: secondary glaucoma (30), retinal detachment (2), iritis (2), and end/panophthalmitis (2). The clinical symptomatology and morphology of the secondary glaucoma caused by the i.o. melanomas did not differ from that due to other, non-neoplastic etiologies. In almost all of the 36 cases the eyes revealed unilateral severe opacity of the media. It is important that one consider an intraocular melanoma in cases of secondary glaucoma, retinal detachment, or intraocular inflammation in which the etiology is uncertain. This is also true in cases of blind, painful eyes in which there is no obvious etiology. Early diagnosis is of vital interest to the patient because this group, in which the malignant melanoma was unsuspected, may be, as suspected in this study, is characterised by extreme aggressivness and invasive capacity. One third of these eyes revealed extension of tumor through the sclera and optic nerve. Also these tumors often revealed more malignant cell types.

journal_name

Klin Monbl Augenheilkd

authors

Völcker HE,Naumann GO

subject

Has Abstract

pub_date

1976-03-01 00:00:00

pages

311-7

issue

3

eissn

0023-2165

issn

1439-3999

journal_volume

168

pub_type

杂志文章
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    更新日期:1994-01-01 00:00:00

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    abstract::Corneal changes are typical for infantile glaucoma. In newborns, Descemet's membrane and the stroma are still soft, and distend when intraocular pressure rises. Cell counts were performed under the reflecting microscope to determine whether the endothelium is affected when corneal diameter increases and changes occur ...

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    更新日期:1992-03-01 00:00:00

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    doi:

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    更新日期:1976-06-01 00:00:00

  • [Lymphatic congestion of the conjunctiva after pre-auricular lymph node excision].

    abstract:PATIENT:A 68-year-old woman presented with massive congestion of lymphatic vessels of temporal inferior conjunctiva two months after extirpation of the parotic gland for an aciniform epithelioma on the same side. Clinical findings of the right and left eye were unremarkable otherwise. The congestion resolved spontaneou...

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  • [Survival after treatment for malignant choroidal melanoma: comparison between conservative therapy (Ru106/Rh106 applicator) and enucleation with and without postoperative irradiation to the orbit; 1960 to 1979].

    abstract::The survival rate was calculated using the life table method in 1,501 patients suffering from choroidal melanomas and treated in 10 eye hospitals in the GDR between 1960 and 1979. The results of treatment by (1) enucleation, (2) enucleation with postoperative irradiation of the orbit and (3) local irradiation with 106...

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    doi:10.1055/s-2008-1054859

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    更新日期:1983-06-01 00:00:00

  • [Information system in ophthalmology].

    abstract:BACKGROUND:Rapid advances in digital imaging technology that characterised the early part of the 21 (st) century have caused modern hospital information systems (HIS) to face a big challenge. One of the key goals of their reorganisation is integration based on open standards in order to achieve optimal interoperability...

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    更新日期:2008-12-01 00:00:00

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    更新日期:1988-06-01 00:00:00

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  • [Congenital fibrosis syndrome. Considerations on etiology, genetics and surgical therapy].

    abstract::Fibrosis syndrome has been a well-known clinical entity for more than a century. Nevertheless, there are still some unresolved questions concerning its etiology, chronological course, and optimal timing of surgery. On the basis of their experience in 12 cases (2 unilateral, 10 bilateral, 7 with eye muscles and/or lid ...

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  • [Biometry of the anterior chamber of the eye in Nd:YAG laser iridectomy].

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    更新日期:1990-03-01 00:00:00

  • [Lowering of intraocular pressure by aqueous solution of bupranolol in chronic uncomplicated glaucoma simplex (author's transl)].

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    doi:

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    更新日期:1979-05-01 00:00:00

  • [Intrabulbar and peribulbar reactive lymphoid hyperplasia].

    abstract::Report on a 69-year-old woman with a choroidal and a large peribulbar tumor. A scan ultrasonography of the peribulbar mass revealed a homogeneous structure of the lymphoma/sarcoma/pseudo-tumor type. Histological examination disclosed a reactive lymphoid hyperplasia without "Dutcher bodies", and consistent with a benig...

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    doi:10.1055/s-2008-1057457

    authors: Haddad R,Slezak H,Till P

    更新日期:1980-02-01 00:00:00

  • [Ocular pulse amplitude during manipulation of systemic perfusion parameters].

    abstract:BACKGROUND:The mechanism for the control of choroidal perfusion is unclear. The present study was designed to investigate for the effect of standardized alteration of systemic perfusion parameters on choroidal hemodynamics in healthy volunteers. METHODS:Intraocular pressure (IOP; German abbreviation: IOD), Ocular Puls...

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    更新日期:1998-10-01 00:00:00

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    doi:

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    更新日期:1975-09-01 00:00:00

  • [The effect of levobunolol eyedrops on trabecular outflow of aqueous humor in chronic simple glaucoma].

    abstract::The present paper reports a double-blind, cross-over, randomized study in which 31 patients (62 eyes) suffering from open-angle glaucoma were included. These patients were treated for one year with 0.5% levobunolol and 0.5% timolol ophthalmic solutions and followed up. Tonographic examinations of outflow facility show...

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    doi:

    authors: Călugăru M

    更新日期:1989-03-01 00:00:00