Abstract:
:Out of 1300 eyes enucleated between 1966-1974, 300 subsequently revealed histologically-proved malignant melanomas of the uvea. In 264 cases the clinical diagnosis was correctly made. In 36 cases the i.o. malignant melanomas were clinically unsuspected. The incorrect clinical diagnoses included: secondary glaucoma (30), retinal detachment (2), iritis (2), and end/panophthalmitis (2). The clinical symptomatology and morphology of the secondary glaucoma caused by the i.o. melanomas did not differ from that due to other, non-neoplastic etiologies. In almost all of the 36 cases the eyes revealed unilateral severe opacity of the media. It is important that one consider an intraocular melanoma in cases of secondary glaucoma, retinal detachment, or intraocular inflammation in which the etiology is uncertain. This is also true in cases of blind, painful eyes in which there is no obvious etiology. Early diagnosis is of vital interest to the patient because this group, in which the malignant melanoma was unsuspected, may be, as suspected in this study, is characterised by extreme aggressivness and invasive capacity. One third of these eyes revealed extension of tumor through the sclera and optic nerve. Also these tumors often revealed more malignant cell types.
journal_name
Klin Monbl Augenheilkdjournal_title
Klinische Monatsblatter fur Augenheilkundeauthors
Völcker HE,Naumann GOsubject
Has Abstractpub_date
1976-03-01 00:00:00pages
311-7issue
3eissn
0023-2165issn
1439-3999journal_volume
168pub_type
杂志文章abstract::A 19-year-old woman presented in the latent phase of secondary syphilis with chronic bilateral anterior uveitis and a slightly elevated optic disk with indistinct margins in the left eye; this was interpreted as a meningitis of the optic nerve. Serologic examination revealed the syphilitic infection, which had not pre...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050356
更新日期:1987-03-01 00:00:00
abstract:BACKGROUND:The Mulvihill-Smith syndrome consists of a large number of stigmata. A few of them are also seen in the LEOPARD syndrome. In both syndromes keratoconus has not yet been reported. PATIENT:We present a twenty-year-old male patient suffering from keratoconus in connection with a Mulvihill-Smith syndrome. A ker...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045490
更新日期:1994-07-01 00:00:00
abstract::Natural treatment methods are currently becoming more and more interesting, in part due to recent results of experimental and clinical research. It has been shown that light of certain wavelengths has a systemic immunosuppressive effect. It therefore seemed logical to expose patients suffering from chronic iridocyclit...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050221
更新日期:1988-07-01 00:00:00
abstract::After a discussion of the pathomechanism of frontobasal cranial injury with a consecutive chiasmal lesion and diabetes insipidus due to a fracture of the basis of the skull, a personal observation of bitemporal hemianopia with a transient diabetes insipidus after a frontal motorcycle crash is recorded. A short survey ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-07-01 00:00:00
abstract:INTRODUCTION:Sarcoidosis can manifest itself in a variety of affection patterns in the eye. Early diagnosis and treatment are of crucial importance. Therefore the following three cases present occular symptoms associated with sarcoidosis. METHODS:Three case reports are described. RESULTS:We report three cases with pa...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0032-1328160
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Infections with varicella zoster virus may involve the optic nerve and the retina. Different pathomechanisms have been discussed. We present a case with an autoimmune inflammatory reaction according to the clinical course. PATIENT:A 69-year-old female was referred to our clinic because of suspected bilatera...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1034771
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND:Transmitted in an autosomal dominant fashion, the pattern dystrophies involve the retinal pigment epithelium and the external macular retina and are usually divided into four different entities. However, a progression from one form to another is possible, various forms may coexist in the same patient and a c...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035218
更新日期:1996-05-01 00:00:00
abstract::In the last four years we have treated with the mobile argon-laser beam 25 cases of aphakic pupillary block glaucoma (p. b. g.). According to the time of manifestation of the p. b. g. the patients were divided into an "early" and a "late" group. In the "early" group (17 eyes) the glaucoma manifested itself 1--4 days a...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-08-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of an intravitreal dexamethasone implant (Ozurdex®) in patients with cystoid macular oedema (CME) suffering from non-infectious uveitis. METHODS:Monocentric, retrospective, single-arm analysis in 49 patients (59 implanted eyes) with inactive uveitis, in whom CME had been unresponsive t...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0042-102058
更新日期:2016-05-01 00:00:00
abstract:INTRODUCTION:Until now, venous pressure within the eye has widely been equated with intraocular pressure (IOP). Measurements with dynamometers calibrated in instrument units or in force showed that the retinal venous pressure (RVP) may be higher than the IOP in glaucoma patients. In this study, the RVP was measured wit...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-1318-9991
更新日期:2021-01-12 00:00:00
abstract:BACKGROUND:Malignant melanoma of the choroid is the most common ocular primary malignancy, but is still a rare tumour. The occurrence of bilateral uveal melanoma is exceedingly rare. The probability of any one individual developing bilateral melanoma is estimated to be 1 to 50 million. MATERIALS AND METHODS:A retrospe...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2007-963519
更新日期:2007-10-01 00:00:00
abstract:PURPOSE:The purpose of this retrospective study is to compare the results of deep sclerectomy versus trabeculectomy for IOP reduction and the respective complication rates. METHODS:199 patients were treated by deep sclerectomy and 80 patients by trabeculectomy between 2000 and 2005. Retrospective results for IOP reduc...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1027599
更新日期:2008-12-01 00:00:00
abstract::In 1876 A. Weber introduced chemically from P. jaborandi isolated Pilocarpium muriaticum into the ophthalmological therapy. One year later it was used as a local drug to lower the intraocular pressure in glaucoma and replaced in the following years the extract of Calabar bean (Eserine). Clinical and pharmacological da...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 历史文章,杂志文章
doi:
更新日期:1976-11-01 00:00:00
abstract::An endogenous endophthalmitis is a severe, potentially blinding intraocular infection due to haematogenous spread of germs. In Europe, gram-positive bacteria and Candida albicans are common causative organisms. Compared to post-operative cases of endophthalmitis, endogenous endophthalmitis is relatively rare, accounti...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2008-1027611
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND:IR-photothermal ablation has, for some time, been described as an alternative to UV photoablation with Excimer lasers. Both procedures are based on different laser-tissue-interactions. IR solid state lasers have cost advantages over UV laser technology and allow a broader clinical use. New beam shaping princ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2008-1034776
更新日期:1999-04-01 00:00:00
abstract:BACKGROUND:The treatment of therapy-resistant secondary glaucoma with cyclodestructive approaches may give rise to unsatisfactory intraocular pressure results, leading to phthisis. A final option may be the implantation of an external glaucoma drainage system (GDS). A consecutive positioning of the drainage system unde...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:10.1055/s-2007-963181
更新日期:2007-08-01 00:00:00
abstract::Three variants of a new anomaloscope principle are described. This principle is distinguished by the fact that for generation of the mixed color and the reference color three interference filters with narrow band widths are used instead of an expensive dispersion prism. In the first variant the brightness of the mixed...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1055221
更新日期:1982-10-01 00:00:00
abstract:BACKGROUND:The difference in the ocular pulse amplitude between an individual's eyes may reflect abnormalities of the cerebrovascular circulation and has been shown to be helpful in assessing patients with cavernous sinus arteriovenous fistulas. HISTORY AND SIGNS:A 71-year-old woman presented with episcleral injection...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2004-812855
更新日期:2004-05-01 00:00:00
abstract::The suitability of ultrasonography, computer tomography and Octopus perimetry is illustrated with reference to an investigation carried out in 60 patients. First, the characteristic symptoms are described, depending on the localization of the lesion in the visual pathway. Then the advantages and disadvantages of the v...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1055172
更新日期:1982-08-01 00:00:00
abstract::The beta-blocker Metipranolol is discussed with reference to a pilot study and a double-blind study. It was found to be remarkably effective in lowering intraocular pressure. No statistically significant difference was found between Metipranolol and Timolol with regard to their effect on intraocular pressure and blood...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:10.1055/s-2008-1054859
更新日期:1983-06-01 00:00:00
abstract::A large variety of diseases may cause a subretinal neovascularization originating from choroidal vessels. Four cases of parapillary choroidal neovascularisation are described, including neovascularization caused by senile and myopic degeneration, by drusen of the optic nerve head, and by angioid streaks. Obliteration ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050277
更新日期:1988-10-01 00:00:00
abstract::Mycotic Septicaemia (especially with the Candida species) is not an uncommon hazard of hospitalized patients, especially those on intravenous hyperalimentation. Two such patients with endogenous mycotic bilateral endophthalmitis are presented. In spite of typical ocular symptoms diagnosis was delayed. Two further unil...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-03-01 00:00:00
abstract:BACKGROUND:We present the description of a successful outcome of intravitreal triamcinolone injection (IVTA) in a patient with cystoid macular oedema (CME) and severe retinal vasculitis suggestive of ocular Behçet's disease. HISTORY AND SIGNS:A healthy 32 year-old Caucasian man presented initially with right retinal v...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1027351
更新日期:2008-05-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the visual outcome and endothelial cell density in the first series of 100 eyes after Descemet membrane endothelial keratoplasty (DMEK) for the treatment of Fuchs endothelial dystrophy. DESIGN:This was a non-randomised prospective clinical trial. METHODS:The first 100 con...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:10.1055/s-0029-1245446
更新日期:2010-06-01 00:00:00
abstract::A survey is presented of orthoptic exercises practiced over the last 120 years. An attempt is made to deduce attitudes to the exercises from contemporary sensory theories. The currently prevalent nihilistic attitude toward orthoptic training is discussed. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 历史文章,杂志文章
doi:10.1055/s-2008-1057189
更新日期:1981-03-01 00:00:00
abstract::In this contribution the authors present the results of treatment by pars plana vitrectomy in a consecutive series of 200 patients with proliferative retinopathy. Anatomical success was achieved in 82% of the cases of simple vitreous hemorrhages, in 63% and 67% respectively of the cases of traction detachment with or ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050630
更新日期:1986-04-01 00:00:00
abstract::Intraocular pressure (IOP) of 617 eyes was measured with both an AO non-contact tonometer (NCT) and a Goldmann applanation tonometer (GAT). - Statistical evaluation and the scattergram gave the following results: Correlation coefficient r = 0.74. Regression line y = 3.01 + 0.8x. Close agreement between mean GAT (17.8 ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057700
更新日期:1980-11-01 00:00:00
abstract::Computerized threshold perimetry of the central 30 degrees was performed on 69 eyes of 36 patients (men and women of all age groups and with different types of diabetes) one day before and one month after panretinal photocoagulation by argon laser. An average of 900 spots were placed in a chessboard pattern in three s...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050103
更新日期:1988-03-01 00:00:00
abstract::The term glaucoma is used as a melting pot of many different diseases which have in common that the retinal ganglion cells and their axons are damaged. Untreated, apoptosis can be induced causing ganglion cell death which subsequently leads to typical glaucomatous damage at the optic nerve head, scotomas of the visual...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0031-1299246
更新日期:2012-02-01 00:00:00
abstract::a) Punctum plasty (eversion of the lacrimal point): This simple method results in a permanently enlarged punctum. A 4-0 silk suture is passed through the vertical part of the canaliculus and the conjunctiva, drawing them together very tightly. The thread falls out after 4-6 weeks. b) Management of trichiasis: Electrol...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1046212
更新日期:1990-05-01 00:00:00