Abstract:
BACKGROUND:Vitamin A deficiency is a leading cause of blindness in childhood in the developing countries. In developed countries xerophthalmia occurs mainly as secondary hypovitaminosis due to malabsorption in chronic alcoholism or intestinal disorders. PATIENT AND METHODS:A 24-year-old female patient complained of night blindness since one week. There was a history of pancreas tail resection combined with radiation due to a papillary low grade cystic carcinoma at the age of 15. During a review period of 9 years of follow-up there was a slow disseminated metastatic spread including the liver. Despite a progressive tumor cachexia the patient was practising a profession. Visual acuity was 20/20 OU with normal visual fields. Dark adaptation was reduced to one log unit and scotopic electroretinography was extinguished. Serum vitamin A level was reduced to 75 ng/ml (normal range 400-700 ng/ml). RESULTS:Under vitamin A substitution dark adaption and scotopic electroretinography normalized and night blindness disappeared within 7 days. CONCLUSIONS:In malabsorption syndromes, especially in combination with liver manifestations, xerophthalmia should be considered as a potential complication. Vitamin A substitution should be administered if necessary. In cases of malignant tumors differential diagnosis includes the cancer associated retinopathy (CAR).
journal_name
Klin Monbl Augenheilkdjournal_title
Klinische Monatsblatter fur Augenheilkundeauthors
Schönherr Udoi
10.1055/s-2008-1034956subject
Has Abstractpub_date
1998-08-01 00:00:00pages
108-11issue
2eissn
0023-2165issn
1439-3999journal_volume
213pub_type
杂志文章abstract::Oxidative stress at the retinal pigment epithelium (RPE) is involved in the pathophysiology of age-related macula degeneration (ARMD). Observations on a clinical or laboratory level have revealed that supplementation of antioxidative scavengers failed in many cases. A potential therapeutic target is the cellular signa...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2008-1027600
更新日期:2009-01-01 00:00:00
abstract::Thirty-six patients with postoperative microstrabismus (24 of them without or with only a slight amblyopia, 12 with severe unilateral amblyopia) and three control groups (normal binocular, long-term monocular, and inexperienced monocular subjects) were tested by their ability to hit 14 vertical sticks set in varied po...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050933
更新日期:1985-05-01 00:00:00
abstract::Intraocular pressure (IOP) of 617 eyes was measured with both an AO non-contact tonometer (NCT) and a Goldmann applanation tonometer (GAT). - Statistical evaluation and the scattergram gave the following results: Correlation coefficient r = 0.74. Regression line y = 3.01 + 0.8x. Close agreement between mean GAT (17.8 ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057700
更新日期:1980-11-01 00:00:00
abstract:BACKGROUND:The aim of this research is to catalogue the increasing number of side effects of medications on the eyes and, by putting this catalogue into a data bank, to make it available for use in hospitals. Here a deliberate search is made for medications, which could possibly cause certain side effects as well as a ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2008-1035248
更新日期:1996-05-01 00:00:00
abstract::A 27 year old male patient with a subretinal granuloma was diagnosed as having a serologically established toxocara infection (Immunoprecipitation test in living larva). Calcifications could be demonstrated in X-ray and CT-scan imaging. The significance of calcifications for the differential diagnosis of retinoblastom...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1046304
更新日期:1990-11-01 00:00:00
abstract:BACKGROUND:Glaucoma is the main cause of irreversible blindness in the world. Because of the increasing mean age, glaucoma is expected to become more common in the developing countries. Besides tonometry and perimetry the appearance of the optic nerve head is a main part of glaucoma diagnosis. Ethnic differences have t...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0028-1109644
更新日期:2009-10-01 00:00:00
abstract::Nine months after leaving the Lebanon, a four-year-old immigrant boy presented with a 5 months history of blepharitis. The lesion remained therapy-resistant for aminoglycoside antibiotics. Six months later, the patient presented with an indolent granulomatous necrotizing purulent blepharitis and follicular conjunctivi...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045741
更新日期:1992-03-01 00:00:00
abstract::The author presents a case of exogenous, retrocorneal, limbal infiltration due to chromomycosis, following cataractextraction. Since the etiology of this keratitis was not recognized at the beginning, steroids were applied causing an exacerbation of the keratitis with hypopyoniritis. A perforating, excentric keratopla...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract::Seventy-eight contact lens patients issued with soft HEMA lenses were examined in order to establish reasons for intolerance. The examination was carried out in conjunction with a questionnaire designed to furnish information about the habits of the contact lens patients. Less than 50% of the patients had been advised...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057272
更新日期:1981-08-01 00:00:00
abstract::A 36-years aged woman suffering from migraine used Ergosanol special-suppositories. An edema of the retina with star figure appeared in both eyes with only a few months distance. After putting away that drug visual acuity restituted completely in spite of a partial neuritic atrophy of the optic nerve in the first suff...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-11-01 00:00:00
abstract:BACKGROUND:Several enzyme defects of the galactose pathway may lead to cataract formation. We report on a family with familiar cataract. PATIENTS:A 2-year-old Turkish girl (daughter of first cousins) presented with dense cortical and subcapsular opacifications and mature cataract respectively. Bilateral phacectomy, pl...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1034710
更新日期:1999-10-01 00:00:00
abstract::In this study the Reichert non-contact tonometer (NCT II) was compared with the Goldmann applanation tonometer (GAT) in 25 subjects (50 eyes; pressure range 9-17 mmHg). The relationship NCT/GAT fulfilled the conditions required for legal verification. Marked differences between the readings of both instruments can be ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1046068
更新日期:1991-09-01 00:00:00
abstract::In 40.8% of 169 eyes affected with diabetic preretinopathy (verified by fluorescein angiography) arteriovenous shunt vessels were found. These vessels occur with significant prevalence in eyes with areas of retinal capillary occlusions, and in cases with diabetes of long duration. There is strong evidence that AV shun...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057587
更新日期:1980-06-01 00:00:00
abstract::Mycotic Septicaemia (especially with the Candida species) is not an uncommon hazard of hospitalized patients, especially those on intravenous hyperalimentation. Two such patients with endogenous mycotic bilateral endophthalmitis are presented. In spite of typical ocular symptoms diagnosis was delayed. Two further unil...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to describe the effectiveness of aflibercept in treatment-naive patients with neovascular age related macular degeneration (nAMD) and the impact of patients' residential distance to the clinic and patients' mobility on therapy in a pro re nata regime. METHODS:A retrospective dataset ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-1008-9357
更新日期:2020-06-01 00:00:00
abstract::In a series of 6000 cases of pseudophakia following extracapsular cataract extraction and implantation of Simcoe-type posterior chamber lenses, observed for a minimum of 20 months, the incidence of retinal detachment was 21 cases (0.33%). Significant risk factors include male sex (18/21, 82%), high myopia (axial lengt...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050061
更新日期:1988-01-01 00:00:00
abstract::Intact or denuded bovine corneas were incubated in the presence of 14lC GlcN and parts of the proteoglycan-glycoprotein complexes of the stroma were extracted by 0.15M NaCl and successively by 1.0M CaCl2. The specific activities of total GAG and KS were determined. In the presence of the epithelial layer the biosynthe...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1977-12-01 00:00:00
abstract::In 64 eyes the combined procedure (group I) and in 67 aphacic eyes a trabeculotomy (group II) was performed. There were different types of glaucoma. Re-examinations wer done 6 months and 1--10 years postoperatively. No definite differences of operative or postoperative complications existed between the two groups. In ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-10-01 00:00:00
abstract::This review summarizes the knowledge and highlights recent advances in clinical research of retinopathy of prematurity (ROP). This disease is still important, because improvements in neonatal intensive care during the last years have increased the survival of the most immature newborns, but did not diminish the ROP fr...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2004-812886
更新日期:2004-03-01 00:00:00
abstract::The present study consists of light- and electron-microscopic examination of excised cornea in a case of lipid keratopathy (Schnyder) in which a perforating keratoplasty was performed. It demonstrates the deposition of cristalline and non-cristalline substances in the corneal epithelium as well as the anterior half of...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-09-01 00:00:00
abstract::Background To evaluate the technique of inverted internal limiting membrane (ILM) flaps for the management of large macular holes and autologous ILM free flaps for non-closing macular holes. Patients and methods All macular holes were treated with pars plana vitrectomy and dual blue assisted ILM flap technique. The in...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0042-119694
更新日期:2017-04-01 00:00:00
abstract::By means of torsional shift operation, or "rotatory Kestenbaum procedure" - in which both ocular bulbs are rotated to the side to which the head is inclined - head malpostures can be eliminated or alleviated in three out of four cases. This applies both to the smaller group of patients with true nystagmus compensation...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050307
更新日期:1988-12-01 00:00:00
abstract::A report is given of a case of a unilateral condition of this type in a 30-year-old woman, who was observed and repeatedly photographed for more as 7 years. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-09-01 00:00:00
abstract::From an original group of 36 Patients (15 with relatively advanced chronic open-angle glaucoma and 21 with ocular hypertension) 21 (seven glucoma and 14 ocular hypertension) were well controlled with Timolol alone or in combination with other pressure-lowering drugs after a three years' observation period. Dropouts oc...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057259
更新日期:1981-07-01 00:00:00
abstract:BACKGROUND:We investigated the presence of Nicotinamid-adenin-dinucleotid-phosphat (NADPH)-diaphorase activity in endothelial cells of the human uveal vessels, using a histochemical procedure which presumably localizes the reaction product nitric oxide. MATERIAL AND METHODS:11 donor eyes destined for corneal transplan...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035414
更新日期:1995-02-01 00:00:00
abstract::Noninfectious ulceration of the peripheral cornea remains a major diagnostic and therapeutic challenge. The pathogenesis in most of these disorders is unclear, however, on the basis of systemic connective tissue diseases, autoimmune mechanisms are most likely involved. The peripheral cornea has distinct morphological ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2008-1035173
更新日期:1996-02-01 00:00:00
abstract:OBJECTIVE:To study the learning risk of a new surgical technique, the deep sclerectomy (DS), which may be complicated with a perforation of the trabeculodescemetic membrane. To do so, we compared the results and the complications of patients who underwent DS transformed in trabeculectomy (DSt) and those of patients who...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035050
更新日期:1997-05-01 00:00:00
abstract::The clinical application of TV fluorescein angiography with subsequent image analysis as performed on a patient with familial Mediterranean fever (FMF), who was suffering from an arterial branch occlusion, is discussed. In addition, the diagnostic relevance of rheologic parameters to the diagnostic evaluation of retin...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050888
更新日期:1985-02-01 00:00:00
abstract::In an attempt to determine the accuracy of ultrasound biometry, the spherical equivalent of the refraction obtained after ECCE and implantation of a posterior chamber IOL in 1663 patients was compared to the desired refraction determined prior to surgery. Follow up time was 21 months on the average. In only 7.4% of th...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1046055
更新日期:1991-08-01 00:00:00
abstract::It has been shown by a series of 127 dacryocystorhinostomies using the Toti technique, that this operation, which is independent of age or aethiology, can be performed using a simple procedure and a short hospitalization time. The success rate of over 90% indicates that this operation should be used as a standard proc...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-02-01 00:00:00