Quantitative analysis of retinal OCT.


:Clinical acceptance of 3-D OCT retinal imaging brought rapid development of quantitative 3-D analysis of retinal layers, vasculature, retinal lesions as well as facilitated new research in retinal diseases. One of the cornerstones of many such analyses is segmentation and thickness quantification of retinal layers and the choroid, with an inherently 3-D simultaneous multi-layer LOGISMOS (Layered Optimal Graph Image Segmentation for Multiple Objects and Surfaces) segmentation approach being extremely well suited for the task. Once retinal layers are segmented, regional thickness, brightness, or texture-based indices of individual layers can be easily determined and thus contribute to our understanding of retinal or optic nerve head (ONH) disease processes and can be employed for determination of disease status, treatment responses, visual function, etc. Out of many applications, examples provided in this paper focus on image-guided therapy and outcome prediction in age-related macular degeneration and on assessing visual function from retinal layer structure in glaucoma.


Med Image Anal


Medical image analysis


Sonka M,Abràmoff MD




Has Abstract


2016-10-01 00:00:00












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    abstract::Phase contrast, a noninvasive microscopy imaging technique, is widely used to capture time-lapse images to monitor the behavior of transparent cells without staining or altering them. Due to the optical principle, phase contrast microscopy images contain artifacts such as the halo and shade-off that hinder image segme...

    journal_title:Medical image analysis

    pub_type: 杂志文章


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  • Dynamically constructed network with error correction for accurate ventricle volume estimation.

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    pub_type: 杂志文章


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  • Directional wavelet based features for colonic polyp classification.

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    pub_type: 杂志文章


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  • Continuous diffusion signal, EAP and ODF estimation via Compressive Sensing in diffusion MRI.

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    pub_type: 杂志文章


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  • Interactive training system for interventional electrocardiology procedures.

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    pub_type: 杂志文章


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    pub_type: 杂志文章


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    journal_title:Medical image analysis

    pub_type: 杂志文章


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    journal_title:Medical image analysis

    pub_type: 杂志文章


    authors: Zhang T,Huang Y,Zhao L,He Z,Jiang X,Guo L,Hu X,Liu T

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    journal_title:Medical image analysis

    pub_type: 杂志文章


    authors: Weldeselassie YT,Barmpoutis A,Atkins MS

    更新日期:2012-08-01 00:00:00

  • Bayesian principal geodesic analysis for estimating intrinsic diffeomorphic image variability.

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    journal_title:Medical image analysis

    pub_type: 杂志文章


    authors: Zhang M,Fletcher PT

    更新日期:2015-10-01 00:00:00

  • Vessel extraction from non-fluorescein fundus images using orientation-aware detector.

    abstract::The automatic extraction of blood vessels in non-fluorescein eye fundus images is a tough task in applications such as diabetic retinopathy screening. However, vessel shapes have complex variations, and accurate modeling of retinal vascular structures is challenging. We have therefore developed a new approach to accur...

    journal_title:Medical image analysis

    pub_type: 杂志文章


    authors: Yin B,Li H,Sheng B,Hou X,Chen Y,Wu W,Li P,Shen R,Bao Y,Jia W

    更新日期:2015-12-01 00:00:00

  • Multiple hypothesis template tracking of small 3D vessel structures.

    abstract::A multiple hypothesis tracking approach to the segmentation of small 3D vessel structures is presented. By simultaneously tracking multiple hypothetical vessel trajectories, low contrast passages can be traversed, leading to an improved tracking performance in areas of low contrast. This work also contributes a novel ...

    journal_title:Medical image analysis

    pub_type: 杂志文章


    authors: Friman O,Hindennach M,Kühnel C,Peitgen HO

    更新日期:2010-04-01 00:00:00

  • Unsupervised boundary delineation of spinal neural foramina using a multi-feature and adaptive spectral segmentation.

    abstract::As a common disease in the elderly, neural foramina stenosis (NFS) brings a significantly negative impact on the quality of life due to its symptoms including pain, disability, fall risk and depression. Accurate boundary delineation is essential to the clinical diagnosis and treatment of NFS. However, existing clinica...

    journal_title:Medical image analysis

    pub_type: 杂志文章


    authors: He X,Zhang H,Landis M,Sharma M,Warrington J,Li S

    更新日期:2017-02-01 00:00:00