Abstract：
:Clinical acceptance of 3-D OCT retinal imaging brought rapid development of quantitative 3-D analysis of retinal layers, vasculature, retinal lesions as well as facilitated new research in retinal diseases. One of the cornerstones of many such analyses is segmentation and thickness quantification of retinal layers and the choroid, with an inherently 3-D simultaneous multi-layer LOGISMOS (Layered Optimal Graph Image Segmentation for Multiple Objects and Surfaces) segmentation approach being extremely well suited for the task. Once retinal layers are segmented, regional thickness, brightness, or texture-based indices of individual layers can be easily determined and thus contribute to our understanding of retinal or optic nerve head (ONH) disease processes and can be employed for determination of disease status, treatment responses, visual function, etc. Out of many applications, examples provided in this paper focus on image-guided therapy and outcome prediction in age-related macular degeneration and on assessing visual function from retinal layer structure in glaucoma.
journal_name
Med Image Analjournal_title
Medical image analysisauthors
Sonka M,Abràmoff MDdoi
10.1016/j.media.2016.06.001subject
Has Abstractpub_date
2016-10-01 00:00:00pages
165-169eissn
1361-8415issn
1361-8423pii
S1361-8415(16)30081-0journal_volume
33pub_type
社论abstract：:In this paper, we present a graph-based concurrent brain tumor segmentation and atlas to diseased patient registration framework. Both segmentation and registration problems are modeled using a unified pairwise discrete Markov Random Field model on a sparse grid superimposed to the image domain. Segmentation is addres...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2014.02.006
更新日期：2014-05-01 00:00:00
abstract：:Prostate brachytherapy is a treatment for prostate cancer using radioactive seeds that are permanently implanted in the prostate. The treatment success depends on adequate coverage of the target gland with a therapeutic dose, while sparing the surrounding tissue. Since seed implantation is performed under transrectal ...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2012.06.001
更新日期：2012-10-01 00:00:00
abstract：:Knowledge of whole heart anatomy is a prerequisite for many clinical applications. Whole heart segmentation (WHS), which delineates substructures of the heart, can be very valuable for modeling and analysis of the anatomy and functions of the heart. However, automating this segmentation can be challenging due to the l...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2019.101537
更新日期：2019-12-01 00:00:00
abstract：:With the development of deep learning, its application in diagnosis of benign and malignant thyroid nodules has been widely concerned. However, it is difficult to obtain medical images, resulting in insufficient number of data, which contradicts the large amount of data required for acquiring effective deep learning d...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2020.101819
更新日期：2021-01-01 00:00:00
abstract：:Interpretation of ultrasound videos of the fetal heart is crucial for the antenatal diagnosis of congenital heart disease (CHD). We believe that automated image analysis techniques could make an important contribution towards improving CHD detection rates. However, to our knowledge, no previous work has been done in t...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2016.11.006
更新日期：2017-02-01 00:00:00
abstract：:Although there are many algorithms available in the literature aimed at segmentation and model reconstruction of 3D angiographic images, many are focused on characterizing only a part of the vascular network. This study is motivated by the recent emerging prospects of whole-organ simulations in coronary hemodynamics, ...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2007.06.012
更新日期：2007-12-01 00:00:00
abstract：:The spinal cord is an essential and vulnerable component of the central nervous system. Differentiating and localizing the spinal cord internal structure (i.e., gray matter vs. white matter) is critical for assessment of therapeutic impacts and determining prognosis of relevant conditions. Fortunately, new magnetic re...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2014.01.003
更新日期：2014-04-01 00:00:00
abstract：:High-dimensional pathological images produced by Immunohistochemistry (IHC) methods consist of many pathological indexes, which play critical roles in cancer treatment planning. However, these indexes currently cannot be utilized in survival prediction because joining them with patients' clinicopathological features (...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2020.101640
更新日期：2020-05-01 00:00:00
abstract：:Over the past 20 years, the field of medical image registration has significantly advanced from multi-modal image fusion to highly non-linear, deformable image registration for a wide range of medical applications and imaging modalities, involving the compensation and analysis of physiological organ motion or of tissu...
journal_title：Medical image analysis
pub_type： 社论
doi：10.1016/j.media.2016.06.031
更新日期：2016-10-01 00:00:00
abstract：:A stochastic finite element framework is presented for the simultaneous estimation of the cardiac kinematic functions and material model parameters from periodic medical image sequences. While existing biomechanics studies of the myocardial material constitutive laws have assumed known tissue kinematic measurements, a...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/s1361-8415(03)00066-5
更新日期：2003-12-01 00:00:00
abstract：:Fast and accurate 2D/3D registration plays an important role in many applications, ranging from scientific and engineering domains all the way to medical care. Today's predominant methods are based on computationally expensive approaches, such as virtual forward or back projections, that limit the real-time applicabil...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2020.101815
更新日期：2021-01-01 00:00:00
abstract：:We propose in this article a content-based image retrieval (CBIR) method for diagnosis aid in medical fields. In the proposed system, images are indexed in a generic fashion, without extracting domain-specific features: a signature is built for each image from its wavelet transform. These image signatures characterize...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2009.11.004
更新日期：2010-04-01 00:00:00
abstract：:We have developed a new technique for extracting histological parameters from multi-spectral images of the ocular fundus. The new method uses a Monte Carlo simulation of the reflectance of the fundus to model how the spectral reflectance of the tissue varies with differing tissue histology. The model is parameterised ...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2006.05.007
更新日期：2006-08-01 00:00:00
abstract：:In-silico continuum simulations of organ and tissue scale physiology often require a discretisation or mesh of the solution domain. Cubic Hermite meshes provide a smooth representation of anatomy that is well-suited for simulating large deformation mechanics. Models of organ mechanics and deformation have demonstrated...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2011.06.010
更新日期：2011-12-01 00:00:00
abstract：:Numerous algorithms are available for segmenting medical images. Empirical discrepancy metrics are commonly used in measuring the similarity or difference between segmentations by algorithms and "true" segmentations. However, one issue with the commonly used metrics is that the same metric value often represents diffe...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2019.101601
更新日期：2020-02-01 00:00:00
abstract：:In order to improve the accuracy of image-guided neurosurgery, different biomechanical models have been developed to correct preoperative images with respect to intraoperative changes like brain shift or tumor resection. All existing biomechanical models simulate different anatomical structures by using either appropr...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/s1361-8415(02)00059-2
更新日期：2002-12-01 00:00:00
abstract：:Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is increasingly being used for the detection and diagnosis of breast cancer. Compared to mammography, DCE-MRI provides higher sensitivity, however its specificity is variable. Moreover, DCE-MRI data analysis is time consuming and depends on reader expertis...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2014.12.001
更新日期：2015-02-01 00:00:00
abstract：:This paper describes a new robust and fully automatic method for calibration of three-dimensional (3D) freehand ultrasound called Confhusius (CalibratiON for FreeHand UltraSound Imaging USage). 3D Freehand ultrasound consists in mounting a position sensor on a standard probe. The echographic B-scans can be localized i...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2004.06.021
更新日期：2005-02-01 00:00:00
abstract：:Pseudo-healthy synthesis is the task of creating a subject-specific 'healthy' image from a pathological one. Such images can be helpful in tasks such as anomaly detection and understanding changes induced by pathology and disease. In this paper, we present a model that is encouraged to disentangle the information of p...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2020.101719
更新日期：2020-08-01 00:00:00
abstract：:A new information-theoretic approach is presented for finding the registration of volumetric medical images of differing modalities. Registration is achieved by adjustment of the relative position and orientation until the mutual information between the images is maximized. In our derivation of the registration proced...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/s1361-8415(01)80004-9
更新日期：1996-03-01 00:00:00
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journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2019.01.007
更新日期：2019-04-01 00:00:00
abstract：:Atlas-based methods for automated preoperative planning of the femoral stem implant in total hip arthroplasty are described. Statistical atlases are constructed from a number of past preoperative plans prepared by experienced surgeons in order to represent the surgeon's expertise of the planning. Two types of atlases ...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2011.10.005
更新日期：2012-02-01 00:00:00
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journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2018.02.008
更新日期：2018-05-01 00:00:00
abstract：:A multiple hypothesis tracking approach to the segmentation of small 3D vessel structures is presented. By simultaneously tracking multiple hypothetical vessel trajectories, low contrast passages can be traversed, leading to an improved tracking performance in areas of low contrast. This work also contributes a novel ...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2009.12.003
更新日期：2010-04-01 00:00:00
abstract：:This paper describes a method for the enhancement of curvilinear structures such as vessels and bronchi in three-dimensional (3-D) medical images. A 3-D line enhancement filter is developed with the aim of discriminating line structures from other structures and recovering line structures of various widths. The 3-D li...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/s1361-8415(98)80009-1
更新日期：1998-06-01 00:00:00
abstract：:With the advent of large-scale imaging studies and big health data, and the corresponding growth in analytics, machine learning and computational image analysis methods, there are now exciting opportunities for deepening our understanding of the mechanisms and characteristics of heart disease. Two emerging fields are ...
journal_title：Medical image analysis
pub_type： 社论,评审
doi：10.1016/j.media.2016.06.027
更新日期：2016-10-01 00:00:00
abstract：:Label fusion is a critical step in many image segmentation frameworks (e.g., multi-atlas segmentation) as it provides a mechanism for generalizing a collection of labeled examples into a single estimate of the underlying segmentation. In the multi-label case, typical label fusion algorithms treat all labels equally - ...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2014.06.005
更新日期：2014-10-01 00:00:00
abstract：:In this work we propose a comprehensive study of Digital Stent Enhancement (DSE), from the analysis of the requirements to the validation of the proposed solution. First, we derive the stent visualization requirements in the context of the clinical application and workflow. Then, we propose a DSE algorithm combining a...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2011.03.002
更新日期：2011-08-01 00:00:00
abstract：:This paper presents a new approach to the simulation of soft tissues deformation suitable for real time computation, particularly intriguing for medical applications. The approach implements a quasi-static solution for elastic global deformations of objects filled with fluid and fibers, which can be a good approximati...
journal_title：Medical image analysis
pub_type： 杂志文章
doi：10.1016/j.media.2012.04.002
更新日期：2012-07-01 00:00:00
abstract：:After two decades of increasing interest and research activity, computer-assisted diagnostic approaches are reaching the stage where more routine deployment in clinical practice is becoming a possibility [Kruppinski, E.A., 2004. Computer-aided detection in clinical environment: Benefits and challenges for radiologists...
journal_title：Medical image analysis
pub_type： 杂志文章,评审
doi：10.1016/j.media.2005.06.003
更新日期：2006-04-01 00:00:00
