A Novel Recombinant Canine Adenovirus Type 1 Detected from Acute Lethal Cases of Infectious Canine Hepatitis.

abstract：:To study IgG-specific subclasses of hepatitis B virus (HBV) surface antigen (anti-HBs), in different populations in Taiwan, a comparison was made between 104 chronic carriers (60 male and 44 female) and 439 recovered individuals (247 male and 192 female). Biochemical analyses of aspartate aminotransferase (AST) and al...

journal_title：Viral immunology

authors： Tsai TH,Huang CF,Wei JC,Ho MS,Wang L,Tsai WY,Lin CC,Xu FL,Yang CC

更新日期：2006-07-01 00:00:00

abstract：:Essen regimen, the Thai Red Cross two-site ID regimen, Zagreb schedule, and the eight-site ID regimen are the standard rabies vaccines recommended by the World Health Organization (WHO). In this study, a liposomal rabies vaccine (LipoRV) was developed, which was found to facilitate the production of rabies virus neutr...

journal_title：Viral immunology

authors： Miao L,Yang Y,Yan M,Li Y,Zhao J,Guo J,Zheng D

更新日期：2017-12-01 00:00:00

abstract：:Toll-like receptor (TLR)3 signaling pathway is known to induce type 1 interferons (IFNs) and proinflammatory mediators leading to antiviral response against many viral infections. Double-stranded ribonucleic acid (dsRNA) has been shown to act as a ligand for TLR3 and, as such, has been a focus as a potential antiviral...

journal_title：Viral immunology

authors： Ahmed-Hassan H,Abdul-Cader MS,Ahmed Sabry M,Hamza E,Sharif S,Nagy E,Abdul-Careem MF

更新日期：2018-07-01 00:00:00

abstract：:To prepare the dominant multiepitope fusion antigen ROP2-SAG1 (RSmultiepitope) from Toxoplasma gondii in a prokaryotic system, the major immunodominant region (MIR) of the human hepatitis B virus core antigen (HBcAg(MIR)) was used as a delivery vector. The gene encoding the RSmultiepitope was inserted into HBcAg(MIR),...

journal_title：Viral immunology

authors： Wang W,Feng F,Lv J,Xie Z,Chen J,Zhang L,Li W

更新日期：2017-09-01 00:00:00

abstract：:Adenoviral vector has been extensively studied as a vaccine platform because of its ability to induce potent cellular and humoral immunity. One main advantage of adenoviral vectors is their natural tropism for mucosal surfaces, which makes them ideal for the purpose of mucosal vaccination against pathogens that prefer...

journal_title：Viral immunology

authors： Santosuosso M,McCormick S,Xing Z

更新日期：2005-01-01 00:00:00

abstract：:C57BL/6 mice can generate a type-specific and class IH-2Kb-restricted CTL response against histocompatible AKR/Gross murine leukemia virus (MuLV) cell surface antigen positive (GCSA+) tumor cells. These anti-AKR/Gross MuLV CTL are also known to lyse SC.Kb/623 target cells expressing the molecular MuLV clone AKR623 (de...

journal_title：Viral immunology

authors： White HD,Roeder DA,Lam T,Green WR

更新日期：1994-01-01 00:00:00

abstract：:The JHM strain of mouse hepatitis virus (JHMV) is rapidly cleared from the central nervous system (CNS) by CD8(+) T cells. In the absence of CD4(+) T cells, fewer CD8(+) T cells are found within the CNS in association with a coordinate increase in apoptotic lymphocytes. Previous data suggested that CD4(+) T cells may ...

journal_title：Viral immunology

authors： Zhou J,Hinton DR,Stohlman SA,Liu CP,Zhong L,Marten NW

更新日期：2005-01-01 00:00:00

abstract：:Stage of liver fibrosis is critical for treatment decision and prediction of outcomes in chronic hepatitis C (CHC) patients. We evaluated the diagnostic accuracy of transient elastography (TE)-FibroScan and noninvasive serum markers tests in the assessment of liver fibrosis in CHC patients, in reference to liver biops...

journal_title：Viral immunology

authors： Omran D,Zayed RA,Nabeel MM,Mobarak L,Zakaria Z,Farid A,Hassany M,Saif S,Mostafa M,Saad OK,Yosry A

更新日期：2018-05-01 00:00:00

abstract：:Expression of the high-affinity interleukin 2 receptor alpha chain (CD25) was used to monitor antigen-specific activation of T lymphocyte subsets (CD4+, CD8+, and gammadelta T cells) from cattle immunized with modified live bovine herpesvirus-1 (BHV-1). Calves seronegative for BHV-1 were either vaccinated with one dos...

journal_title：Viral immunology

authors： Endsley JJ,Quade MJ,Terhaar B,Roth JA

更新日期：2002-01-01 00:00:00

abstract：:Hepatitis E virus (HEV) is one of the primary causative agents of acute hepatitis. It is noteworthy that HEV can develop chronic infection and even lead to liver cirrhosis; however, the mechanism has not been revealed. In this study, the ELISA assay was used to detect protein levels, and we found that HEV open reading...

journal_title：Viral immunology

authors： Lei Q,Li L,Cai J,Huang W,Qin B,Zhang S

更新日期：2016-03-01 00:00:00

abstract：:Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe respiratory disease with significant mortality. Two testing methods are currently used for MERS-CoV diagnostics: nucleic acid detection (the gold standard) and serological analysis. In this study, we evaluated the detection of MERS-CoV-IgG in suspec...

journal_title：Viral immunology

authors： Alhetheel A,Altalhi H,Albarrag A,Shakoor Z,Mohamed D,El-Hazmi M,Somily A,Barry M,Bakhrebah M,Nassar M

更新日期：2017-11-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) continues to be an economically important infectious disease of swine. Mechanisms governing activation of the innate immune response to PRRSV remain to be elucidated. Virulence differences observed between PRRSV isolates have been attributed to replication ab...

journal_title：Viral immunology

authors： Loving CL,Brockmeier SL,Vincent AL,Lager KM,Sacco RE

更新日期：2008-09-01 00:00:00

abstract：:Besides being an important target in the antiretroviral therapy against the human immunodeficiency virus type 1 (HIV-1), the HIV-1 reverse transcriptase (RT) enzyme has potential as a vaccine antigen. In this study, we explored the ability of plasmid-encoded RT to induce cell-mediated immune responses. The strategy fo...

journal_title：Viral immunology

authors： Hallengärd D,Wahren B,Bråve A

更新日期：2013-04-01 00:00:00

abstract：:We investigated the duration of humoral responses to dengue virus infection in individuals who recalled experiencing dengue fever-like illnesses at the time of the Second World War, when dengue fever epidemics occurred throughout the Pacific and Southeast Asia. In July 1943 dengue fever reappeared in Hawaii following ...

journal_title：Viral immunology

authors： Imrie A,Meeks J,Gurary A,Sukhbaatar M,Truong TT,Cropp CB,Effler P

更新日期：2007-12-01 00:00:00

abstract：:Serum antibodies against the E6 and E7 proteins of human papillomavirus (HPV) 16 and 18 are associated with cervical cancer. The aim of this study was to investigate the presence of local antibodies against HPV in cervicovaginal washings (CWs). In this study antibodies against the native HPV16 and HPV18 E6/E7 proteins...

journal_title：Viral immunology

authors： Tjiong MY,Zumbach K,Schegget JT,van der Vange N,Out TA,Pawlita M,Struyk L

更新日期：2001-01-01 00:00:00

abstract：:Severe acute respiratory syndrome (SARS) is a deadly and highly infectious disease caused by SARS Coronavirus (SARS-CoV). Inactivated SARS-CoV has been explored as a vaccine against SARS-CoV; however, current knowledge of inactivated SARS-CoV vaccine is quite limited. We attempted to investigate the effects of differe...

journal_title：Viral immunology

authors： Gai W,Zou W,Lei L,Luo J,Tu H,Zhang Y,Wang K,Tien P,Yan H

更新日期：2008-03-01 00:00:00

abstract：:Exposure to environmental contaminants has a profound effect on immune function, yet mechanistic understanding of how pollutants deregulate immune responses has, for many chemicals, remained elusive. Available data suggest that certain pollutants alter host immune responses and increase susceptibility to viral infecti...

journal_title：Viral immunology

authors： Lawrence BP

更新日期：2007-07-01 00:00:00

abstract：:Genetic polymorphism of IFNAR-1 plays a large role in determining the clearance or chronicity after hepatitis B virus (HBV) exposure. However, it is not clear whether type I interferon receptor-1 (IFNAR-1) variations continuously exert their effects to influence the final outcomes following HBV chronicity, including a...

journal_title：Viral immunology

authors： He XX,Chang Y,Jiang HJ,Tang F,Meng FY,Xie QH,Li PY,Song YH,Lin JS

更新日期：2010-06-01 00:00:00

abstract：:Adaptive B cell response is a key arm of protective immunity against influenza viruses. Owing to the acutely infectious and cytopathic nature of these viruses, efficient containment of viral spread relies on the prompt provision of protective antibodies to the site of virus infection, the respiratory tract (RT). To ac...

journal_title：Viral immunology

authors： Takahashi Y,Onodera T,Adachi Y,Ato M

更新日期：2017-07-01 00:00:00

abstract：:Current treatments for hepatitis C infection have limited efficacy, and there is no vaccine available. The goal of this study was to compare the immune response to several immunization combinations against hepatitis C virus (HCV). Six groups of mice were immunized at weeks 0, 4, and 8 with different combinations of a ...

journal_title：Viral immunology

authors： Ghorbani M,Nass T,Azizi A,Soare C,Aucoin S,Giulivi A,Anderson DE,Diaz-Mitoma F

更新日期：2005-01-01 00:00:00

abstract：:The implications of sequential prime and challenge with mismatched influenza A viruses is a concern in mammals, including humans. We evaluated the ability of pigs affected with vaccine-associated enhanced respiratory disease (VAERD) to generate a humoral immune response against the heterologous challenge virus incitin...

journal_title：Viral immunology

authors： Gauger PC,Loving CL,Lager KM,Janke BH,Kehrli ME Jr,Roth JA,Vincent AL

更新日期：2013-10-01 00:00:00

abstract：:Anogenital warts are a common clinical manifestation of genital infection with human papillomavirus type 6b (HPV-6b). Accumulating data indicate that an effective cellular immune response is required for the control of HPV infections. However, in a minority of patients there is a high rate of recurrence of wart lesion...

journal_title：Viral immunology

authors： Blanchet JS,Sonnex C,Gough GW,Warren AP

更新日期：2007-04-01 00:00:00

abstract：:Nucleotide-binding domain leucine repeats (NLRs) are required for the recognition of various molecules that are expressed within microbes and are able to actuate appropriate immune responses via activation of cytokines. The current study evaluates the expression levels of NLRP1 and NLRC4, which are components of infla...

journal_title：Viral immunology

authors： Askari A,Nosratabadi R,Khaleghinia M,Zainodini N,Kennedy D,Shabani Z,Kazemi Arababadi M

更新日期：2016-11-01 00:00:00

abstract：:Hepatitis C virus (HCV) signifies an important health issue as it is a globally prevalent pathogen and poses a great threat to human health. Direct antiviral therapy became a landmark in treatment against chronic HCV infection as they have proven to increase sustained virological response (SVR) rate, provide shortened...

journal_title：Viral immunology

authors： Aziz H,Aziz M,Gill ML

更新日期：2018-04-01 00:00:00

abstract：:Studies of immune function in human immunodeficiency virus (HIV)-infected children are important, because functional abnormalities can precede CD4+ T-cell loss and are associated with the development of opportunistic and bacterial infections. We sought to correlate clinical parameters and immunological function with H...

journal_title：Viral immunology

authors： Peters VB,Mayer L,Sperber KE

更新日期：1999-01-01 00:00:00

abstract：:This study aimed to investigate the seroprevalence of cytomegalovirus (CMV) infection and risk factors associated with CMV acquisition among pregnant women in Zimbabwe. In a cross-sectional study, pregnant women were recruited in late gestation, seeking antenatal care at council clinics in three high-density suburbs i...

journal_title：Viral immunology

authors： Mhandire D,Duri K,Kaba M,Mhandire K,Musarurwa C,Chimusa E,Munjoma P,Mazengera L,Stray-Pedersen B,Dandara C

更新日期：2019-09-01 00:00:00

abstract：:One of the most profound enigmas in B cell biology is how activation-induced deaminase (AID) is targeted to a very small region of DNA in the immunoglobulin loci. Two specific regions are singled out: the variable region of 2 kb that contains rearranged genes on the heavy, κ light, and λ light chain loci, and the swit...

journal_title：Viral immunology

authors： Heltzel JMH,Gearhart PJ

更新日期：2020-05-01 00:00:00

abstract：:Human papillomavirus (HPV) regulation of host immune response leads to cervical lesions. In particular, natural killer (NK) cells are crucial for HPV control. Since specific HLA-I/KIR interactions modify NK cell activation, we analyzed HLA-C and KIR alleles in HPV infection and lesion development in 150 controls, 33 c...

journal_title：Viral immunology

authors： Rizzo R,Gentili V,Rotola A,Bortolotti D,Cassai E,Di Luca D

更新日期：2014-11-01 00:00:00

abstract：:Pretreatment of mice iv with syngeneic spleen cells modified with soluble HSV envelope antigens induced an anti-HSV antibody hyporesponsiveness following challenge with infectious virus. The epitope density on the HSV-modified spleen cells was quantitated using a photon-counting spectrofluorimeter so that observed imm...

journal_title：Viral immunology

authors： Wilson LA,Thompson JJ,Ohkawa S,Scott DW

更新日期：1992-07-01 00:00:00

abstract：:Insights into the host factors that contribute to an effective antiviral immune response may be obtained by examining global gene expression in simian human immunodeficiency virus (SHIV)-infected nonhuman primates that exhibit different virological outcomes. Immune responses and gene expression profiles in peripheral ...

journal_title：Viral immunology

authors： Chung HK,Pise-Masison CA,Radonovich MF,Brady J,Lee JK,Cheon SY,Markham P,Cristillo A,Pal R

更新日期：2008-12-01 00:00:00