Implication of HLA-C and KIR alleles in human papillomavirus infection and associated cervical lesions.

abstract：:Virus-specific cytotoxic T lymphocytes (CTLs) are crucial for the control of respiratory syncytial virus (RSV) infection. This study has identified CTL epitopes of the RSV N protein in healthy subjects. We screened the primary structure of the N protein for HLA-A 0201-binding amino acid consensus motifs, identifying t...

journal_title：Viral immunology

authors： Terrosi C,Di Genova G,Savellini GG,Correale P,Blardi P,Cusi MG

更新日期：2007-09-01 00:00:00

abstract：:Severe acute respiratory syndrome (SARS) is a deadly and highly infectious disease caused by SARS Coronavirus (SARS-CoV). Inactivated SARS-CoV has been explored as a vaccine against SARS-CoV; however, current knowledge of inactivated SARS-CoV vaccine is quite limited. We attempted to investigate the effects of differe...

journal_title：Viral immunology

authors： Gai W,Zou W,Lei L,Luo J,Tu H,Zhang Y,Wang K,Tien P,Yan H

更新日期：2008-03-01 00:00:00

abstract：:Studies of immune function in human immunodeficiency virus (HIV)-infected children are important, because functional abnormalities can precede CD4+ T-cell loss and are associated with the development of opportunistic and bacterial infections. We sought to correlate clinical parameters and immunological function with H...

journal_title：Viral immunology

authors： Peters VB,Mayer L,Sperber KE

更新日期：1999-01-01 00:00:00

abstract：:Regulatory/suppressor cells have become rehabilitated and respectable. They returned as regulators of autoimmunity, but are now acknowledged to critically influence immunity to foreign antigens, such as those found on microbes. This review describes the principal types of regulatory cells that influence immunity to mi...

journal_title：Viral immunology

authors： Suvas S,Rouse BT

更新日期：2005-01-01 00:00:00

abstract：:Transmissible spongiform encephalopathies are fatal neurodegenerative disorders that include Creutzfeldt-Jakob disease in humans, bovine spongiform encephalopathy and scrapie in sheep and goats. Transmissible spongiform encephalopathies are thought by some to result from changes in the conformation of a membrane glyco...

journal_title：Viral immunology

authors： Daude N

更新日期：2004-01-01 00:00:00

abstract：:In this study we investigated the efficacy of a multigenic DNA prime/modified vaccinia Ankara (MVA)boost vaccine approach, followed by mucosal challenge with highly pathogenic simian-human immunodeficiency virus (SHIV) 89.6P, using different routes for vaccine delivery. After three times of DNA priming (SIVmac239, Gag...

journal_title：Viral immunology

authors： Stolte-Leeb N,Bieler K,Kostler J,Heeney J,Haaft PT,Suh YS,Hunsmann G,Stahl-Hennig C,Wagner R

更新日期：2008-06-01 00:00:00

abstract：:Subjects > or = 55 years of age were immunized with attenuated varicella zoster virus (VZV) vaccine (live) or with the same vaccine, which had been heated to 56 degrees C for 7 days (killed). The ability of subjects' blood lymphocytes to lyse target cells infected with VZV was determined before and 3 months after immu...

journal_title：Viral immunology

authors： Hayward AR,Buda K,Jones M,White CJ,Levin MJ

更新日期：1996-01-01 00:00:00

abstract：:In cattle, cells with functional characteristics similar to those of natural killer (NK) cells are difficult to detect. However, lymphokine-activated killer (LAK) cells can be detected readily after in vitro activation of peripheral blood mononuclear leukocytes (PBML) with interleukin-2 (IL-2). In the present study, w...

journal_title：Viral immunology

authors： Campos M,Ohmann HB,Rapin N,Babiuk LA

更新日期：1991-01-01 00:00:00

abstract：:Fowl aviadenoviruses (FAdVs) are distributed worldwide in poultry farms. Some FAdVs are the causative agents of inclusion body hepatitis and hydropericardium syndrome that cause significant economic losses to the poultry industry. In contrast with human adenovirus, the study of the molecular biology of FAdV is still f...

journal_title：Viral immunology

authors： Deng L,Griffin BD,Pei Y,Leishman D,McBey BA,Sharif S,Nagy É

更新日期：2017-11-01 00:00:00

abstract：:Virus-based influenza vaccines induce less protection in old compared to young subjects due, in part, to age-associated alterations in the immune response. This study shows that old mice produce a less diverse HI antibody response after immunization than adult mice. However, immunization of old and young mice with pla...

journal_title：Viral immunology

authors： Radu DL,Antohi S,Bot A,Weksler ME,Bona C

更新日期：1999-01-01 00:00:00

abstract：:Genetic polymorphism of IFNAR-1 plays a large role in determining the clearance or chronicity after hepatitis B virus (HBV) exposure. However, it is not clear whether type I interferon receptor-1 (IFNAR-1) variations continuously exert their effects to influence the final outcomes following HBV chronicity, including a...

journal_title：Viral immunology

authors： He XX,Chang Y,Jiang HJ,Tang F,Meng FY,Xie QH,Li PY,Song YH,Lin JS

更新日期：2010-06-01 00:00:00

abstract：:Th17 cells and the secreting cytokines play an important role in the immune response and inflammation that is induced by hepatitis B virus (HBV). However, it remains not fully elucidated how the antiviral agents affect Th17 cytokines and signal pathway. Telbivudine therapy has been proved to inhibit HBV replication ef...

journal_title：Viral immunology

authors： Hao C,Wang J,Kang W,Xie Y,Zhou Y,Ma L,Peng M,Bai X,Lian J,Jia Z

更新日期：2013-10-01 00:00:00

abstract：:A 90-amino acid peptide from the simian rotavirus SA-11 nonstructural protein, NSP4 was linked to the N-terminus of the Ricinus communis A-B toxin B subunit protein (RTB) and synthesized in Escherichia coli. Recombinant RTB and the NSP4(90)::RTB fusion protein bound artificial receptor glycoprotein asialofetuin in an ...

journal_title：Viral immunology

authors： Choi NW,Estes MK,Langridge WH

更新日期：2006-04-01 00:00:00

abstract：:To improve efficacy, especially for the cell-mediated response to inactivated viral vaccines, a modified levamisole (LMS) adjuvant formulation, designated LMS+, was evaluated for its efficacy in mice and chickens, using Newcastle Disease Virus (NDV) as a model pathogen. Compared with oil adjuvant, the killed NDV in LM...

journal_title：Viral immunology

authors： Yin J,Jin H,Kang Y,Xiao C,Zhao L,Li X,Ding Z,Yang F,Zhu Q,Wang B

更新日期：2006-07-01 00:00:00

abstract：:Serial virus specimens rescued from rabbits, experimentally infected with bovine immunodeficiency (BIV) strain R29, were monitored for changes in quasispecies population, using the single-strand conformation polymorphism (SSCP) analysis. The generation of characteristic SSCP patterns enables the rapid differentiation ...

journal_title：Viral immunology

authors： Kalvatchev Z,Walder R,Garzaro D,Barrios M

更新日期：2000-01-01 00:00:00

abstract：:Reovirus has previously been classified into three serotypes based on hemagglutination inhibition assays. In the present study, the specificity of cytotoxic T lymphocytes (CTL) generated in reovirus type 3-infected C3H/HeN mice was investigated at the population and clonal levels. Short-term CTL lines generated in res...

journal_title：Viral immunology

authors： Hogan KT,Cashdollar LW

更新日期：1991-10-01 00:00:00

abstract：:Outbreaks of the highly pathogenic H5N1 virus in poultry and humans are ongoing. Vaccination is an efficient method for prevention of H5N1 infection. Using chickens and ducks, we assessed the efficacy of a vaccine comprising H5N1 hemagglutinin (HA) protein produced in a baculovirus expression system. The immunized chi...

journal_title：Viral immunology

authors： Park EH,Song BM,Yum J,Kim JA,Oh SK,Kim HS,Cho GJ,Seo SH

更新日期：2014-11-01 00:00:00

abstract：:CD8(+) T-cell-mediated pulmonary immunopathology in respiratory virus infection is mediated in large part by antigen-specific TNF-α expression by antiviral effector T cells, which results in epithelial chemokine expression and inflammatory infiltration of the lung. To further define the signaling events leading to lun...

journal_title：Viral immunology

authors： Srikiatkhachorn A,Chintapalli J,Liu J,Jamaluddin M,Harrod KS,Whitsett JA,Enelow RI,Ramana CV

更新日期：2010-12-01 00:00:00

abstract：:This study aimed to investigate the seroprevalence of cytomegalovirus (CMV) infection and risk factors associated with CMV acquisition among pregnant women in Zimbabwe. In a cross-sectional study, pregnant women were recruited in late gestation, seeking antenatal care at council clinics in three high-density suburbs i...

journal_title：Viral immunology

authors： Mhandire D,Duri K,Kaba M,Mhandire K,Musarurwa C,Chimusa E,Munjoma P,Mazengera L,Stray-Pedersen B,Dandara C

更新日期：2019-09-01 00:00:00

abstract：:Cholangiocarcinoma is a malignancy of the biliary duct system. Presently, these malignant biliary tract diseases are common among the people in Southeast Asia, with the world's highest prevalence in northeastern Thailand and Laos. This carcinoma tends to grow slowly and to infiltrate the walls of the ducts, dissecting...

journal_title：Viral immunology

authors： Pinyosophon A,Wiwanitkit V

更新日期：2002-01-01 00:00:00

abstract：:The ability of a highly divergent antigenic site of foot-and-mouth disease virus (FMDV) of serotype C to elicit neutralizing antibodies has been evaluated in mice and rabbits. The viruses compared, FMDV C-S8c1 and HR, differ in a single amino acid replacement in their capsid proteins, but represent two extreme antigen...

journal_title：Viral immunology

authors： Borrego B,Camarero JA,Mateu MG,Domingo E

更新日期：1995-01-01 00:00:00

abstract：:Highly pathogenic avian influenza (HPAI) H5N1 virus emerged in 1997 as a zoonotic disease in Hong Kong. It has since spread to Asia and Europe and is a serious threat to both the poultry industry and human health. For effective surveillance and possible prevention/control of HPAI H5N1 viruses, it is necessary to under...

journal_title：Viral immunology

authors： Daidoji T,Watanabe Y,Arai Y,Kajikawa J,Hirose R,Nakaya T

更新日期：2017-07-01 00:00:00

abstract：:Natural killer (NK) cells have been suggested to play a protective role in HIV disease progression. One potent effector mechanism of NK cells is antibody-dependent cellular cytotoxicity (ADCC) mediated by antiviral antibodies binding to the FcγRIIIa receptor (CD16) on NK cells. We investigated NK cell-mediated ADCC fu...

journal_title：Viral immunology

authors： Johansson SE,Rollman E,Chung AW,Center RJ,Hejdeman B,Stratov I,Hinkula J,Wahren B,Kärre K,Kent SJ,Berg L

更新日期：2011-10-01 00:00:00

abstract：:Exposure to environmental contaminants has a profound effect on immune function, yet mechanistic understanding of how pollutants deregulate immune responses has, for many chemicals, remained elusive. Available data suggest that certain pollutants alter host immune responses and increase susceptibility to viral infecti...

journal_title：Viral immunology

authors： Lawrence BP

更新日期：2007-07-01 00:00:00

abstract：:Patients with hepatitis B virus (HBV) infection may develop severe chronic liver disease. Carriers of HBV have an increased risk of developing cirrhosis, hepatic decompensation, and hepatocellular carcinoma. Worldwide an estimated 350 million people are infected with HBV, and 15-40% will develop serious sequelae in th...

journal_title：Viral immunology

authors： Filho RM,Carmo RF,Catsman C,Souza C,Silva A,Moura P,Tenorio AL,Vasconcelos LR,Cavalcanti Mdo S,Pereira LM

更新日期：2010-08-01 00:00:00

abstract：:The JHM strain of mouse hepatitis virus (JHMV) is rapidly cleared from the central nervous system (CNS) by CD8(+) T cells. In the absence of CD4(+) T cells, fewer CD8(+) T cells are found within the CNS in association with a coordinate increase in apoptotic lymphocytes. Previous data suggested that CD4(+) T cells may ...

journal_title：Viral immunology

authors： Zhou J,Hinton DR,Stohlman SA,Liu CP,Zhong L,Marten NW

更新日期：2005-01-01 00:00:00

abstract：:Adenoviral vector has been extensively studied as a vaccine platform because of its ability to induce potent cellular and humoral immunity. One main advantage of adenoviral vectors is their natural tropism for mucosal surfaces, which makes them ideal for the purpose of mucosal vaccination against pathogens that prefer...

journal_title：Viral immunology

authors： Santosuosso M,McCormick S,Xing Z

更新日期：2005-01-01 00:00:00

abstract：:Previous research has evaluated antibody responses toward an influenza virus vaccine in the context of deficiencies for vitamins A and D (VAD+VDD). Results showed that antibodies and antibody-forming cells in the respiratory tract were reduced in VAD+VDD mice. However, effectors were recovered when oral supplements of...

journal_title：Viral immunology

authors： Surman SL,Jones BG,Woodland DL,Hurwitz JL

更新日期：2017-12-01 00:00:00

abstract：:Hepatitis B and C infections can be either acute or chronic. The chronic infection can culminate in liver cirrhosis and hepatocellular carcinoma. Influence of the host genetic makeup on conversion of acute to chronic infection, development of cirrhosis, and hepatocellular carcinoma is an interesting area of research. ...

journal_title：Viral immunology

authors： Rehman SU,Rauf M,Abbas Z,Hamed MH,Qadri I

更新日期：2016-12-01 00:00:00

abstract：:Since the WHO declared coronavirus disease 2019 (COVID-19) as a pandemic, huge efforts were made to understand the disease, its pathogenesis, and treatment. COVID-19 is caused by severe acute respiratory syndrome (SARS) coronavirus-2 (SARS-CoV2), which is closely related to SARS-associated coronavirus (SARS-CoV). This...

journal_title：Viral immunology

authors： Assaf AM,Haddadin RN,Akour AA

更新日期：2020-10-05 00:00:00