Abstract:
BACKGROUND AND OBJECTIVES:Local control of disease is one of the main goals of osteosarcoma management. We conducted a retrospective evaluation of 95 operated cases of osteosarcoma over 7 years to know about the factors associated with local recurrence in resource-challenged environment of the developing world. METHODS:The factors which were evaluated and compared between local recurrence and non-local recurrence groups included demographic profile, site of tumor, whether biopsy done outside, type of surgery (limb salvage or amputation), presence of pathological fracture, vicinity of neurovascular bundle, tumor volume, histological subtype, chemotherapy induced necrosis, surgical margins, and delay in surgery. The time to local recurrence after surgery was also noted in the local recurrence group. RESULTS:At a mean follow-up of 2.8 years, biopsy done from outside the treating center and delay in surgery after completion of neo-adjuvant chemotherapy emerged as significant risk factors for local recurrence. Most of the local recurrences (80%) occurred within 12 months of the primary surgery. CONCLUSIONS:Lack of financial resources and availability of few tertiary care centers dealing with musculoskeletal oncology in the developing countries, lead to overburden with a long waiting list for tumor surgery making the scenario different from the Western world.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Poudel RR,Tiwari V,Kumar VS,Bakhshi S,Gamanagatti S,Khan SA,Rastogi Sdoi
10.1002/jso.24602subject
Has Abstractpub_date
2017-04-01 00:00:00pages
631-636issue
5eissn
0022-4790issn
1096-9098journal_volume
115pub_type
杂志文章abstract:BACKGROUND:A person-centered approach to co-decision-making using tailored information respects each woman's preferences and may heighten breast reconstruction satisfaction. METHODS:Women seeking breast reconstruction underwent initial and follow-up consultations wherein suitable options were discussed, and take-away ...
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更新日期:1993-12-01 00:00:00
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