Abstract:
BACKGROUND/OBJECTIVES:Telomere length is a useful biomarker for determining general aging status. Some studies have reported an association between alcohol consumption and telomere length in a general population; however, it is unclear whether the alcohol flush reaction, which is an alcohol-related trait predominantly due to acetaldehyde dehydrogenase deficiency, is associated with telomere length. This cross-sectional study aimed to evaluate the associations of alcohol consumption and alcohol flush reaction with leukocyte telomere length (LTL). SUBJECTS/METHODS:The study included 1,803 Korean adults. Participants provided blood specimens for LTL measurement assay and reported their alcohol drinking status and the presence of an alcohol flush reaction via a questionnaire-based interview. Relative LTL was determined by using a quantitative polymerase chain reaction. Statistical analysis used multiple linear regression models stratified by sex and age groups, and potential confounding factors were considered. RESULTS:Age-specific analyses showed that heavy alcohol consumption (> 30 g/day) was strongly associated with a reduced LTL in participants aged ≥ 65 years (P < 0.001) but not in younger participants. Similarly, the alcohol flush reaction was associated with a reduced LTL only in older participants who consumed > 15 g/day of alcohol (P < 0.01). No significant alcohol consumption or alcohol flush reaction associations with LTL were observed in the sex-specific analyses. CONCLUSIONS:The results suggest that older alcohol drinkers, particularly those with the alcohol flush reaction, may have an accelerated aging process.
journal_name
Nutr Res Practjournal_title
Nutrition research and practiceauthors
Wang H,Kim H,Baik Idoi
10.4162/nrp.2017.11.4.334subject
Has Abstractpub_date
2017-08-01 00:00:00pages
334-339issue
4eissn
1976-1457issn
2005-6168journal_volume
11pub_type
杂志文章abstract:BACKGROUND/OBJECTIVES:Sodium intake is positively associated with blood pressure, which may increase the risk for cardiovascular disease (CVD). Therefore, we assessed the disease burden of CVD attributable to sodium intakes above 2,000 mg/day and prospectively investigated the association between dietary/urinary sodium...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2020.14.5.501
更新日期:2020-10-01 00:00:00
abstract::Zinc is an essential trace element required for bone formation, however not much has been clarified yet for its role in osteoblast. We hypothesized that zinc would increase osteogenetic function in osteoblasts. To test this, we investigated whether zinc treatment enhances bone formation by stimulating osteoblast proli...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2010.4.5.356
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Urbanization and lifestyle changes have resulted in nutrition transition. Over-nutrition causes obesity increase, although malnutrition still exists. This phenomenon is called a double burden of malnutrition (DBM). This study was conducted to confirm the existence of DBM and to investigate the die...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2018.12.5.426
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Helicobacter pylori (H. pylori) colonization of the stomach mucosa and duodenum is the major cause of acute and chronic gastroduodenal pathology in humans. Efforts to find effective anti-bacterial strategies against H. pylori for the non-antibiotic control of H. pylori infection are urgently requi...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2017.11.1.11
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Carnosic acid (CA), found in rosemary (Rosemarinus officinalis) leaves, is known to exhibit anti-obesity and anti-inflammatory activities. However, whether its anti-inflammatory potency can contribute to the amelioration of obesity has not been elucidated. The aim of the current study was to inves...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2014.8.5.516
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Obesity-induced steatohepatitis accompanied by activated hepatic macrophages/Kupffer cells facilitates the progression of hepatic fibrinogenesis and exacerbates metabolic derangements such as insulin resistance. Heme oxyganase-1 (HO-1) modulates tissue macrophage phenotypes and thus is implicated ...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2016.10.6.623
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:We examined dietary fat intake and the major food sources by young children in Korea. SUBJECTS/METHODS:A total of 1,041 children aged 1-5 years were identified from the 2013-2015 Korea National Health and Nutrition Examination Survey. Data on total fat and fatty acid intake were obtained by a sin...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2018.12.4.324
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:A higher frequency of family meals is associated with good dietary habits in young people. This study focused on the relationships of family meal frequency with food neophobia and personality traits in adolescents. SUBJECTS/METHOD:For this purpose, we administered a survey to 495 middle school students in S...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2014.8.4.476
更新日期:2014-08-01 00:00:00
abstract::We evaluated folate status of child-bearing age women diagnosed with abnormal pap smear in the US post-folic acid (FA) fortification era and assessed the determinants of NTD-protective and supra-physiologic (SP) concentrations of folate. The distribution of 843 women according to NTD-protective concentrations of RBC f...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2013.7.4.315
更新日期:2013-08-01 00:00:00
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journal_title:Nutrition research and practice
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doi:10.4162/nrp.2019.13.2.159
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Iron deficiency in early life is associated with developmental problems, which may persist until later in life. The question of whether iron repletion after developmental iron deficiency could restore iron homeostasis is not well characterized. In the present study, we investigated the changes of ...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2015.9.6.613
更新日期:2015-12-01 00:00:00
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journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2019.13.6.543
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Despite the importance of a low-iodine diet (LID) for thyroid cancer patients preparing for radioactive iodine (RAI) therapy, few studies have evaluated dietary intake during LID. This study evaluated the amount of dietary iodine intake and its major food sources during a typical diet and during L...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2016.10.2.167
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:This study investigates correlations between circulating microRNAs (miRNAs) and obesity-related parameters among young women (aged 20-30 years old) in Korea. SUBJECTS/METHODS:We analyzed TaqMan low density arrays (TLDAs) of circulating miRNAs in 9 lean (body mass index [BMI] < 25 kg/m2) and 15 ob...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2020.14.4.412
更新日期:2020-08-01 00:00:00
abstract::The objective of this study was to evaluate the inhibitory activity of natural products, against growth of Escherichia coli (ATCC 25922) and Salmonella typhimurium (KCCM 11862). Chitosan, epigallocatechin gallate (EGCG), and garlic were used as natural bioactives for antibacterial activity. The testing method was carr...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2007.1.4.273
更新日期:2007-01-01 00:00:00
abstract::The purpose of this study was to estimate the daily manganese (Mn) intake of Korean children. This study was done using a three-day dietary intake survey of 257 Korean children (boys 123; girls 134). The Mn intake values were calculated based on a database that provides the Mn content of the frequently consumed Korean...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2011.5.6.548
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Use of smaller plates to control food intake is a commonly recommended strategy for restricting energy intake, despite conflicting results. Therefore, the aim of this study was to examine whether or not three different sizes of plates influence energy intake during a multi-itemed buffet meal in no...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2016.10.5.524
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Isoflavones are widely believed to be beneficial to human health, in relation to their antioxidant potentials. Exercise can cause an imbalance between reactive oxygen species (ROS) and antioxidants. This study was conducted in order to investigate the ability of isoflavones in amelioration of oxid...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2014.8.6.618
更新日期:2014-12-01 00:00:00
abstract::Resistance training (RT) is associated with reduced risk of low grade inflammation related diseases, such as cardiovascular disease and type 2 diabetes. The majority of the data studying cytokines and exercise comes from endurance exercise. In contrast, evidence establishing a relationship between RT and inflammation ...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2010.4.4.259
更新日期:2010-08-01 00:00:00
abstract::The abnormal content of blood lipids often results in metabolic diseases, such as hyperlipidemia and obesity. Many agents, including natural sources from traditional food, have been developed to regulate the blood lipid contents. In this study, we examined the anti-hyperlipidemic activity of Rhynchosia nulubilis seeds...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2013.7.6.453
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Serum ferritin levels are significantly increased after menopause and greatly affect women's health. The aim of this study was to investigate the dietary and non-dietary factors associated with high ferritin levels in postmenopausal women. SUBJECTS/METHODS:Among adult women in 2010-2012, qualifie...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2016.10.1.81
更新日期:2016-02-01 00:00:00
abstract::[This retracts the article on p. 507 in vol. 10, PMID: 27698958.]. ...
journal_title:Nutrition research and practice
pub_type: 杂志文章,撤回出版物
doi:10.4162/nrp.2019.13.1.76
更新日期:2019-02-01 00:00:00
abstract::Beneficial effects of dehydroepiandrosterone (DHEA) supplement on age-associated chronic diseases such as cancer, cardiovascular disease, insulin resistance and diabetes, have been reported. However, its mechanism of action in hepatocellular carcinoma in vivo has not been investigated in detail. We have previously sho...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2008.2.2.80
更新日期:2008-07-01 00:00:00
abstract::Dietary sodium intake is considered one of the major causal factors for hypertension. Thus, to control the increase of blood pressure and reduce the risk of hypertension-related clinical complications, a reduction in sodium intake is recommended. The present study aimed at determining the association of dietary sodium...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2013.7.3.192
更新日期:2013-06-01 00:00:00
abstract::The aim of this study was to investigate the influencing factors that characterize low density lipoprotein (LDL) phenotype and the levels of LDL particle size in healthy Korean women. In 57 healthy Korean women (mean age, 57.4 ± 13.1 yrs), anthropometric and biochemical parameters such as lipid profiles and LDL partic...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2012.6.2.120
更新日期:2012-04-01 00:00:00
abstract::In order to promote foodservice for the elderly, foodservice managers in Continuing Care Retirement Communities (CCRCs) must identify the main factors to enhance the satisfaction and behavioral intentions with food service. The purpose of this study was to investigate the relationships between relationship quality (co...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2011.5.1.73
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:This study examined the effect of nutrition labeling formats on parents' food choices for their children at different restaurant types. SUBJECTS/METHODS:An online survey was conducted with 1,980 parents of children aged 3-12 years. Participants were randomly assigned to fast food or family restau...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2018.12.3.243
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:Chronic hyperglycemia induces oxidative stress via accumulation of reactive oxygen species (ROS) and contributes to diabetic complications. Hyperglycemia induces mitochondrial superoxide anion production through the increased activity of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. ...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2017.11.5.430
更新日期:2017-10-01 00:00:00
abstract::In Korea, chestnut production is increasing each year, but consumption is far below production. We investigated the effect of chestnut extracts on antioxidant activity and anticancer effects. Ethanol extracts of raw chestnut (RCE) or chestnut powder (CPE) had dose-dependent superoxide scavenging activity. Viable numbe...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2011.5.3.185
更新日期:2011-06-01 00:00:00
abstract::This study investigated the effect of physical training and oxidative stress on the antioxidative activity and on plasma lipid profile. Forty eight rats were given either a physical training or no training for 4 weeks and were then subdivided into 3 groups: before-exercise (BE); during-exercise (DE); after-exercise (A...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2007.1.1.14
更新日期:2007-04-01 00:00:00