iTRAQ-coupled 2D LC/MS-MS analysis of CXCR7-transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of potential biomarkers.

abstract：:The outcomes of matched unrelated donor (MUD) hematopoietic stem cell transplantation (HSCT) and immunosuppressive therapy (IST) in patients with severe aplastic anemia (SAA) remain controversial. The clinical outcome in patients that undergo transplantation following failed IST is typically poorer when compared with ...

journal_title：Oncology letters

authors： Hsu SN,Chen JH,Kao WY

更新日期：2014-10-01 00:00:00

abstract：:Chromodomain helicase DNA-binding 5 (CHD5), which is a member of the CHD family, has been identified as a tumor suppressor gene in a variety of malignancies. The aim of the current study was to clarify the clinical significance of CHD5 expression in gastric cancer. CHD5 expression was evaluated using immunohistochemis...

journal_title：Oncology letters

authors： Hashimoto T,Kurokawa Y,Wada N,Takahashi T,Miyazaki Y,Tanaka K,Makino T,Yamasaki M,Nakajima K,Mori M,Doki Y

更新日期：2020-01-01 00:00:00

abstract：:Previous studies have revealed that fibrosis may affect the biological behavior of tumors, however associated research on papillary thyroid microcarcinoma (PTMC) is rare. The aim of the present study was to explore the association between interstitial fibrosis (IF) and the biological behavior of PTMC. In the present s...

journal_title：Oncology letters

authors： Liu X,Zhang S,Gang Q,Shen S,Zhang J,Lun Y,Xu D,Duan Z,Xin S

更新日期：2018-04-01 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC), one of the most common malignant tumors, endangers human health. Recently, the incidence of HNSCC has kept increasing: However, its prognosis has not significantly improved. Understanding the molecular mechanism underlying HNSCC development will therefore provide new stra...

journal_title：Oncology letters

authors： Zou B,Guan X,Zhang W,Wang D,Xu K,Yuan DY,Meng Z,Zhang B

更新日期：2019-12-01 00:00:00

abstract：:We compared the clinical effects and prognosis of patients receiving lymph node dissection after surgical removal of the thyroid tissues and those not receiving it after the removal. A total of 80 patients diagnosed with differentiated thyroid carcinoma (DTC) by our hospital from March 2012 to March 2014 were successi...

journal_title：Oncology letters

authors： Liu B,Qin H,Zhang B,Shi T,Li C,Liu Y,Song M

更新日期：2017-01-01 00:00:00

abstract：:AR-42 is a member of a novelly discovered class of phenylbutyrate-derived histone deacetylase inhibitors, and has a number of antitumor effects in a variety of tumor types; however, the role of AR-42 and its possible mechanisms have not been reported in the treatment of breast cancer. The aim of the present study was ...

journal_title：Oncology letters

authors： Zhou R,Wu J,Tang X,Wei X,Ju C,Zhang F,Sun J,Shuai D,Zhang Z,Liu Q,Lv XB

更新日期：2018-08-01 00:00:00

abstract：:Decreased expression of ten-eleven translocation (TET1, TET2 and TET3) proteins has been reported in various types of cancer. However, the expression levels of TET proteins in cervical cancer (CC) remain to be elucidated. The present study determined the levels of TET1, TET2 and TET3 transcripts in cancerous (n=80) an...

journal_title：Oncology letters

authors： Bronowicka-Kłys DE,Roszak A,Pawlik P,Sajdak S,Sowińska A,Jagodziński PP

更新日期：2017-05-01 00:00:00

abstract：:Acanthus ebracteatus Vahl. is commonly consumed with the aim of curing cancer, inflammatory conditions and skin diseases in traditional Thai medicine. It is known to contain various phytochemicals; however, very little is known about the effects of A. ebracteatus protein hydrolysate on cancer cells, including its mole...

journal_title：Oncology letters

authors： Khamwut A,Jevapatarakul D,Reamtong O,T-Thienprasert NP

更新日期：2019-09-01 00:00:00

abstract：:Lichen sclerosus is a chronic and inflammatory disease. Extensive studies have focused on the epidermis, with the dermis or epidermis-dermis receiving less attention. To investigate the role of galectin-7, a keratinocyte protein, in vulvar lichen sclerosus (VLS) and its potential effects on dermal fibroblasts, immunoh...

journal_title：Oncology letters

authors： Zhao Y,Zhao S,Li H,Qin X,Wu X

更新日期：2018-08-01 00:00:00

abstract：:The prognosis following surgical treatment of gastric carcinoma (GC) or gastroesophageal junction (GEJ) adenocarcinoma remains poor. Although adjuvant chemo-radiotherapy with 5-fluorouracil has been shown to be beneficial, a high rate of distant failure has been reported. Thus, the toxicity profile and efficacy of an ...

journal_title：Oncology letters

authors： Shulman K,Haim N,Wollner M,Bernstein Z,Abdah-Bortnyak R,Bar-Sela G

更新日期：2012-05-01 00:00:00

abstract：:1,6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl] diamantane (DPD), a diamantane derivative, was previously noted as an anticancer compound through anticancer drug screening with NCI-60 human tumor cells. Irinotecan (CPT-11), a semisynthetic derivative of camptothecin, is clinically active in the treatment of colorectal can...

journal_title：Oncology letters

authors： Yang PS,Wang JJ,Wang YH,Jan WC,Cheng SP,Hsu YC

更新日期：2016-05-01 00:00:00

abstract：:Despite all efforts at management, prognosis of advanced lung cancer is extremely poor, with a median survival time of ~1 year. The number of cancer patients aged >70 years is significantly increased among the cancer patient population. The aim of this study was to investigate the clinical importance of age in lung ca...

journal_title：Oncology letters

authors： Tas F,Ciftci R,Kilic L,Karabulut S

更新日期：2013-11-01 00:00:00

abstract：:The present study aimed to evaluate the expression of p53, Ki-67, epidermal growth factor receptor (EGFR) and O6-methylguanine-DNA methyltransferase (MGMT), and to analyze the correlation between their expression and the histological grade of the tumors in 152 patients with gliomas. The tumors were classified accordin...

journal_title：Oncology letters

authors： Hu X,Miao W,Zou Y,Zhang W,Zhang Y,Liu H

更新日期：2013-07-01 00:00:00

abstract：:Oncological and functional prognostic factors for patients with foot sarcomas have yet to be clarified. This study was undertaken to identify the prognostic factors for oncological and functional outcomes and the significance of adjuvant radiotherapy in achieving local control in patients with foot sarcomas. We review...

journal_title：Oncology letters

authors： Kozawa E,Nishida Y,Nakashima H,Tsukushi S,Toriyama K,Kamei Y,Ishiguro N

更新日期：2012-01-01 00:00:00

abstract：:It has been demonstrated that numerous types of metastatic cancer overexpress vacuolar-type H+ (V)-ATPases. It may be possible to inhibit the growth and metastasis of human cancer cells by inhibiting V-ATPases. It was previously reported that diphyllin, a novel V-ATPase inhibitor, can inhibit the migration and invasio...

journal_title：Oncology letters

authors： Pan S,Cai H,Gu L,Cao S

更新日期：2017-11-01 00:00:00

abstract：:Tanshinone IIA exhibits natural antioxidative and antineoplastic activity. However, to the best of our knowledge, the effects of tanshinone IIA on human nasopharyngeal carcinoma cells remains unknown. The present study aimed to investigate whether tanshinone IIA inhibits proliferation and induces apoptosis of human na...

journal_title：Oncology letters

authors： Liu B,Liu L,Zang A,Song Z,Yang H,Wang Z,Shang Y,Ma T,Zhang Y

更新日期：2019-09-01 00:00:00

abstract：:Previous studies have revealed the aberrant expression of a number of microRNAs (miRNA/miRs) in the blood circulation of patients with breast cancer (BC). The aim of the present study was to assess the effect of neoadjuvant chemotherapy on the levels of a panel of BC-associated miRNAs, which are at relatively low (let...

journal_title：Oncology letters

authors： Gezer U,Keskin S,Iğci A,Tükenmez M,Tiryakioğlu D,Cetinkaya M,Dişci R,Dalay N,Eralp Y

更新日期：2014-08-01 00:00:00

abstract：:The aim of this study was to ensure a high dose of intensity modulated radiation therapy (IMRT) was delivered to tumor tissue with a low dose to normal organs. Seldinger interventional techniques were used to inject chemotherapy drugs for nasopharyngeal carcinoma (NPC). IMRT was conducted 3 weeks after intervention. P...

journal_title：Oncology letters

authors： Fen X,Qin W,Bao W,Jiang F,Li B,Hu F,Chen X

更新日期：2013-08-01 00:00:00

abstract：:Invasive breast carcinoma (BRCA) is a serious disease that threatens the survival time of those affected. Alternative splicing (AS) involved in BRCA pathogenesis may be a potential therapeutic target. However, to the best of our knowledge, a systematic analysis of survival-related alternative splicing events (SREs) ha...

journal_title：Oncology letters

authors： Jia K,Wu Y,Huang J,Chen J,Wei H,Wu H

更新日期：2020-08-01 00:00:00

abstract：:The present study aimed to ascertain the significance of topoisomerase II α (TOP2A) and minichromosome maintenance protein (MCM) 2 expression in anal carcinoma. A total of 75 anal lesions were retrieved from the files of the Department of Pathology of Barretos Cancer Hospital (Barretos, Brazil) in order to verify the ...

journal_title：Oncology letters

authors： Scapulatempo-Neto C,Veo C,Fregnani JHTG,Lorenzi A,Mafra A,Melani AGF,Loaiza EAA,Rosa LAR,de Oliveira CM,Levi JE,Longatto-Filho A

更新日期：2017-03-01 00:00:00

abstract：:The current study reports the case of a large retroperitoneal tumor treated with modified simultaneous integrated boost (SIB) radiotherapy. A 45-year-old female presented to the emergency department complaining of left abdominal pain and fever. A computed tomography scan detected a retroperitoneal tumor of 12×16×16 cm...

journal_title：Oncology letters

authors： Nomiya T,Akamatsu H,Harada M,Ota I,Hagiwara Y,Ichikawa M,Miwa M,Mizutani M,Kato T,Nagaoka A,Tomita Y,Nemoto K

更新日期：2015-06-01 00:00:00

abstract：:This study aims to comparatively analyze the impact of laparoscopic myomectomy (LM) and transcervical resection of myoma (TCRM) on ovarian function, immune function and quality of sexual life of patients with hysteromyoma. Two hundred and forty patients with hysteromyoma admitted into the Second Affiliated Hospital of...

journal_title：Oncology letters

authors： Zhang Y,Gu X,Meng Y,Guo H,Du J,Xing W

更新日期：2018-03-01 00:00:00

abstract：:Previous studies have reported that alcohol dehydrogenase (ADH) isoenzymes possess diagnostic value in gastric cancer (GC). However, the prognostic value of ADH isoenzymes in GC remains unclear. The aim of the present study was to identify the prognostic value of ADH genes in patients with GC. The prognostic value of ...

journal_title：Oncology letters

authors： Guo E,Wei H,Liao X,Xu Y,Li S,Zeng X

更新日期：2018-04-01 00:00:00

abstract：:Hepatocellular carcinoma is a serious public health problem in China. The mortality rate associated with the majority of cancer types has decreased as a result of targeted therapy. However, the mortality rates associated with hepatocellular carcinoma have not improved; therefore, the identification of new molecular ta...

journal_title：Oncology letters

authors： Yuan B,Bo W,Feng X,Hu Y,Zeng J

更新日期：2020-12-01 00:00:00

abstract：:The present study aimed to retrospectively review the contribution of 18F-fluorodeoxygluose-positron emission tomography/computed tomography (18F-FDG PET/CT) in the assessment of biochemical recurrence in patients with a diagnosis of local-stage prostate cancer (PCa) who underwent radical prostatectomy (RP) or receive...

journal_title：Oncology letters

authors： Öztürk H,Karapolat I

更新日期：2016-01-01 00:00:00

abstract：:The pharmacological actions of Ophiopogonin D include resistance to cardiovascular and cerebrovascular diseases, anti-aging effects, improvement in learning deficit and dysmnesia, anti-tumor, anti-radiation and anti-inflammatory effects, immunoregulation, and the relief of cough and hepatopulmonary pathological lesion...

journal_title：Oncology letters

authors： Yan Z,Liu G,Liang M,Xu Y

更新日期：2019-02-01 00:00:00

abstract：:Lung cancer is the leading cause of cancer-associated mortality worldwide and its prognosis is poor. Few effective biomarkers for non-small cell lung cancer (NSCLC) have been translated into the clinical practice aiming to assist in the treatment plan design and prognosis evaluation. The aim of the present study was t...

journal_title：Oncology letters

authors： Hao L,Du B,Xi X

更新日期：2017-08-01 00:00:00

abstract：:Corosolic acid (CRA), a pentacyclic triterpene isolated from medicinal herbs, has been reported to exhibit anticancer properties in several cancers. However, the anticancer activity of CRA in osteosarcoma cells is still unclear. In the present study, the inhibitory effect of CRA in osteosarcoma MG-63 cells was investi...

journal_title：Oncology letters

authors： Jia Y,Yuan H,Shan S,Xu G,Yu J,Zhao C,Mou X

更新日期：2016-11-01 00:00:00

abstract：:Chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell disorder. It is characterized by the presence of the Philadelphia (Ph) chromosome, t(9;22)(q34.1;q11.2), which carries the BCR-ABL1 fusion gene. Tyrosine kinase inhibitors (TKIs) have markedly changed the treatment approach of CML and have become the f...

journal_title：Oncology letters

authors： Al-Khallaf H,Alali H,Alkhatti A

更新日期：2018-11-01 00:00:00

abstract：:The inhibitory effect of resveratrol on the growth of gastric cancer cells through downregulation of the Wnt/β-catenin signaling pathway were studied. First we determined the effective concentration of resveratrol on the growth and proliferation of MGC-803 gastric cancer cells. Methylthiazolyl tetrazolium assay showed...

journal_title：Oncology letters

authors： Dai H,Deng HB,Wang YH,Guo JJ

更新日期：2018-08-01 00:00:00