Modification of the Schwartz equations for children increases their accuracy at eGFR > 60 mL/min/1.73 m(2).

Abstract:

AIM:Estimation of eGFR in children with normal kidney function using the Schwartz equations results in underestimating real GFR. MATERIALS AND METHODS:We propose modification of three Schwartz equations - two based on creatinine concentration (eGFRScrBS bedside) and (eGFRScr) and one 3-marker based on creatinine, urea and cystatin C concentrations (eGFRS3M). The iohexol test (reference method) was performed 417 times in 353 children >2 years with mean GFR: 98 ± 31.6 ml/min/1.73m(2). The assessment included also the Filler and Zappitelli equations. The modification was performed using methods: (1) based on equation, eGFRcor = a [eGFR - T] + T, where T = 50, if eGFR > T, and a equals for: eGFRScrBS 1.4043, for eGFRScr 2.0048, for eGFRS3M 1.2951, and (2) based on correction of all coefficients of the original equation. RESULTS:For comparison of all the results and for children with GFR< 60, 60-90, 90-135 and > 135 ml/min/1.73m(2) the correlation coefficient, relative error (RE) and root mean square relative error (RMSRE) was employed and revealed improvement of RE from 25.9 to 6.8 and 3.9% (depending on the correction method) for eGFRScr; from 19 to 8.1 and 3.9% for eGFRScrBS and: from 11.6% to 2.0 and 2.3% for eGFRS3M (respectively). The RMSRE values changed from 30 to 21.3 and 19.8% for eGFRScr, from 25.1 to 21.6 and 19.8% for eGFRScrBS and from 19.1 to 15.8 and 15.3 % for eGFRS3M. CONCLUSIONS:Modifications of Schwartz equations at GFR > 60 ml/min/1.73m(2) significantly improves the accuracy of calculating eGFR. The 3-markers equation is more accurate and should be employed frequently.

journal_name

Ren Fail

journal_title

Renal failure

authors

Zachwieja K,Korohoda P,Kwinta-Rybicka J,Miklaszewska M,Moczulska A,Bugajska J,Berska J,Drożdż D,Pietrzyk JA

doi

10.3109/0886022X.2016.1163152

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

787-98

issue

5

eissn

0886-022X

issn

1525-6049

journal_volume

38

pub_type

杂志文章
  • Protective effect of curcumin on busulfan-induced renal toxicity in male rats.

    abstract:AIM:The aim of this study was to evaluate the effects of curcumin in an experimental model of busulfan-induced renal toxicity with emphasis on importance of histological alterations. METHODS:In this study, we utilized 32 adult male Wistar rats (250 ± 10 g). All the animals were divided into four experimental groups ra...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2020.1818580

    authors: Abdollahifar MA,Ebrahimi V,Aliaghaei A,Raoofi A,Khosravi A,Hasani A,Mehdizadeh A,Asadi M

    更新日期:2020-11-01 00:00:00

  • The effects of proteinuria on urinary cystatin-C and glomerular filtration rate calculated by serum cystatin-C.

    abstract:BACKGROUND:The measurement of glomerular filtration rate (GFR) applying serum creatinine (Cr) does not reflect the GFR of patients accurately, and thus recently, studies on the measurement of GFR applying serum cystatin-C (Cys-C) have been conducted. We investigated the relationship between Cys-C and proteinuria in pat...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2012.672154

    authors: Kim JS,Kim MK,Lee JY,Han BG,Choi SO,Yang JW

    更新日期:2012-01-01 00:00:00

  • Significant benefits after renal transplantation in patients with chronic heart failure and chronic kidney disease.

    abstract:BACKGROUND:Chronic heart failure (CHF) and chronic kidney disease (CKD) are serious medical conditions with significant morbidity and mortality and often coexist. Because of perioperative risks in these patients, they may not be considered a candidate for renal transplantation (RTx). MATERIAL AND METHODS:We compare re...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2014.899474

    authors: Kute VB,Vanikar AV,Patel HV,Gumber MR,Shah PR,Engineer DP,Balwani MR,Gautam RS,Modi PR,Shah VR,Trivedi HL

    更新日期:2014-07-01 00:00:00

  • Role of glutathione for cisplatin nephrotoxicity in young and adult rats.

    abstract::Investigations were done in 10- and 55-day-old Wistar rats. Glutathione (GSH) level in kidney was decreased by 8 mmol buthionine sulfoximine (BSO)/100 g BW. There was no effect on the renal function and nephrotoxicity of cisplatin (0.6 mg CP/100 g BW) in adult rats. In young rats BSO treatment was followed by nephroto...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229309046144

    authors: Appenroth D,Winnefeld K

    更新日期:1993-01-01 00:00:00

  • Effect of sevelamer on dyslipidemia and chronic inflammation in maintenance hemodialysis patients.

    abstract:BACKGROUND:Hemodialysis (HD) patients often experience cardiovascular events, that might be related to altered calcium-phosphate metabolism, dyslipidemia, and chronic inflammation in addition to hypertension. Sevelamer, a non-calcium-containing phosphate binder, may improve the lipid profile of HD patients. However, th...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:

    authors: Yamada K,Fujimoto S,Tokura T,Fukudome K,Ochiai H,Komatsu H,Sato Y,Hara S,Eto T

    更新日期:2005-01-01 00:00:00

  • Acute renal failure in leptospirosis in Uruguay.

    abstract::The present study was carried out to describe epidemiology and clinical pattern of acute renal failure caused by leptospirosis in Uruguay. For these purposes, all literature published in Uruguay was reviewed. Three studies were analyzed: 2 series of patients and 1 case report that summarize 26 cases. The incidence of ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229709026295

    authors: Lombardi R

    更新日期:1997-03-01 00:00:00

  • Association of the angiotensinogen M235T and APO E gene polymorphisms in Turkish type 2 diabetic patients with and without nephropathy.

    abstract:BACKGROUND:Diabetic nephropathy (DN) is a leading cause of diabetes-related morbidity and mortality. The aim of this study was to evaluate the relationship of AGT M235T and apoprotein E (APO E) gene polymorphism with DN in Turkish patients of Type 2 diabetes, and to compare genotype and allele distributions among DN pa...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2011.568133

    authors: Reis KA,Ebinç FA,Koç E,Demirci H,Erten Y,Güz G,Derici UB,Bali M,Söylemezoğlu O,Arınsoy T,Sindel S

    更新日期:2011-01-01 00:00:00

  • Effect of glycine on cisplatin nephrotoxicity and heat-shock protein 70 expression in the rat kidney.

    abstract::Glycine has been shown to protect against cisplatin (CP) nephrotoxicity in rats and to enhance the in vitro expression of heat-shock protein (hsp) 70 in renal epithelial cells following sublethal heat shock. We hypothesized that the protective effect of glycine against CP nephrotoxicity may be due to an up-regulation ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229709026258

    authors: Musio F,Carome MA,Bohen EM,Sabnis S,Yuan CM

    更新日期:1997-01-01 00:00:00

  • Acute kidney injury in patients with pyogenic liver abscess.

    abstract::Incidence of acute kidney injury (AKI) in patients with pyogenic liver abscess is rare. In our study we found AKI in 32.6% of patients with liver abscess. Majority of the patients were in their fifties and sixties. As per acute kidney injury network trial criteria, renal failure was in stage 1 in 26.6%, stage 2 in 40%...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2011.569108

    authors: Sriramnaveen P,Sridhar A,Sandeep Y,Krishnakishore C,Sainaresh V,Manjusha Y,Sivakumar V

    更新日期:2011-01-01 00:00:00

  • Endothelial function and oxidative stress in chronic kidney disease of varying severity and the effect of acute hemodialysis.

    abstract:AIM:Oxidative stress (OS) and endothelial dysfunction are implicated in accelerated atherosclerosis in chronic kidney disease (CKD). We assessed endothelial function, OS, and carotid intimal medial thickness (CIMT) and their correlates in 44 CKD stage 5 patients (group III) before and after hemodialysis (HD), 40 patien...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2011.568138

    authors: Khaira A,Mahajan S,Kumar A,Saraya A,Tiwari SC,Prakash S,Gupta A,Bhowmik D,Agarwal SK

    更新日期:2011-01-01 00:00:00

  • Biological effects of lentivirus-mediated shRNA targeting collagen type I on the mesangial cells of rats.

    abstract:AIM:To investigate the effects of lentivirus-mediated shRNA targeting collagen type I on the mesangial cells of rats and the feasibility of lentivirus-mediated shRNA delivery through renal parenchyma injection. METHODS:Anti-collagen type I shRNA lentiviral vector was constructed, and rat mesangial cells were transfect...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2011.559679

    authors: Zhou C,Shan Y,Zhao H,He P

    更新日期:2011-01-01 00:00:00

  • Interleukin-17 promotes the production of underglycosylated IgA1 in DAKIKI cells.

    abstract:BACKGROUND:Interleukin 17 (IL-17) plays an important role in the pathogenesis of autoimmune diseases and might be associated with IgA nephropathy (IgAN). This study aimed to investigate the effect of IL-17 on autoimmune pathogenesis in IgA nephropathy. METHODS:DAKIKI cells were cultured and stimulated with IL-17 to pe...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2017.1419972

    authors: Lin JR,Wen J,Zhang H,Wang L,Gou FF,Yang M,Fan JM

    更新日期:2018-11-01 00:00:00

  • Efficacy of leflunomide combined with prednisone in the treatment of refractory nephrotic syndrome.

    abstract:OBJECTIVE:To assess the safety and clinical efficacy of leflunomide (LEF) and prednisone on refractory nephrotic syndrome (RNS). METHODS:A total of 52 patients with RNS were treated for 24 weeks between 2010 and 2014 in our hospital. In the treated group, 26 patients were treated with LEF and prednisone, and, in the c...

    journal_title:Renal failure

    pub_type: 杂志文章,随机对照试验

    doi:10.3109/0886022X.2016.1172917

    authors: Liu Y,Qu X,Chen W,Zhang Y,Liu L

    更新日期:2016-11-01 00:00:00

  • Readability and comprehensibility of over-the-counter medication labels.

    abstract::Nonprescription medications are relatively safe, but not risk-free and can lead to serious adverse events, particularly if used contrary to directions or without attention to depicted warnings. The question arises whether the information presented on the product label is readable and comprehensible to the average lay ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2013.872571

    authors: Trivedi H,Trivedi A,Hannan MF

    更新日期:2014-04-01 00:00:00

  • A systematic review on randomized control trials on rennin angiotensin aldosterone system inhibitors role in managing hypertension among hemodialysis patients.

    abstract::Randomized control trials (RCTs) are considered as most rigors way of determining the cause-effect relationship of a treatment and outcome. Activation of rennin angiotensin aldosterone system (RAAS) is an important contributor to hypertension in hemodialysis patients. The prevalence of hypertension in hemodialysis pat...

    journal_title:Renal failure

    pub_type: 杂志文章,评审

    doi:10.3109/0886022X.2016.1138833

    authors: Aftab RA,Khan AH,Adnan AS,Jannah N

    更新日期:2016-01-01 00:00:00

  • Infectious complications of prosthetic arteriovenous grafts for hemodialysis: prevention is better than cure.

    abstract::Synthetic arteriovenous grafts for hemodialysis constitute the second choice in comparison with native arteriovenous fistulas. Lower patency rates and significantly more frequent infections are the main disadvantages of hemodialysis grafts over fistulas. Infectious complications could vary between a simple local eryth...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2014.883910

    authors: Galanopoulos G,Lambidis C

    更新日期:2014-05-01 00:00:00

  • Higher thrombin activatable fibrinolysis inhibitor levels are associated with inflammation in attack-free familial Mediterranean fever patients.

    abstract:BACKGROUND:Coagulation abnormalities have been reported in familial Mediterranean fever (FMF) patients with amyloidosis and nephrotic syndrome; but there is not enough data about the continuity of the thrombogenic activity in FMF patients in clinical remission. The purpose of this study was to assess thrombin activatab...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2014.886935

    authors: Bavbek N,Ceri M,Akdeniz D,Kargili A,Duranay M,Erdemli K,Akcay A,Guz G

    更新日期:2014-06-01 00:00:00

  • The aqueous extract of aged black garlic ameliorates colistin-induced acute kidney injury in rats.

    abstract::The use of colistin in the treatment of multidrug-resistant Gram-negative bacterial infections is restricted due to nephrotoxicity. We investigated the effects of aged black garlic extract (ABGE) on colistin-induced kidney injury in rats. Rats were assigned to four groups. Normal saline was intraperitoneally and intra...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2018.1561375

    authors: Lee TW,Bae E,Kim JH,Jang HN,Cho HS,Chang SH,Park DJ

    更新日期:2019-11-01 00:00:00

  • Ureteral anastomosis with a polyimide stent in rat kidney transplantation.

    abstract::Background: Complications associated with ureteral anastomosis in kidney transplantation are highly prevalent, despite the development of various types of stents. The current stent materials and placement methods have several limitations. This study attempts to provide an alternative by investigating ureteral anastomo...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2020.1726386

    authors: Wang T,Yu Z,Chen C,Song Y,Zeng X,Su Y,Yi C

    更新日期:2020-11-01 00:00:00

  • A prospective study of hepatitis B vaccination - a comparison of responders versus nonresponders.

    abstract::Herein we present one of the largest single-center reports of the response of hemodialysis patients to a two-vaccine hepatitis B virus vaccination protocol in a European dialysis population. A hepatitis B recombinant DNA vaccine, HBvaxPRO, was given at a dose of 40 µg intramuscularly using a four-dose schedule at 0, 1...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2011.559300

    authors: Brown CM,Donlon S,O'Kelly P,Casey AM,Collier C,Conlon PJ,Walshe JJ

    更新日期:2011-01-01 00:00:00

  • Clinicopathologic characteristics and outcomes of lupus nephritis with positive antineutrophil cytoplasmic antibody.

    abstract::Aims: The aim was to determine whether anti-neutrophil cytoplasmic antibody (ANCA)-positive serology in patients with lupus nephritis (LN) is associated with different clinicopathologic features and outcomes.Methods: In our retrospective analysis, 283 patients were enrolled between 2013 and 2018. Thirty-six patients w...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2020.1735416

    authors: Wang S,Shang J,Xiao J,Zhao Z

    更新日期:2020-11-01 00:00:00

  • Unilateral nephrectomy and progression of renal failure.

    abstract::Extensive ablation of renal mass in experimental animals leads to progressive glomerulosclerosis and chronic renal failure (CRF). Clinical studies are far from answering the question whether patients with reduced renal mass are at risk of developing progressive CRF. The aim of our study was to examine the morphologica...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229309054954

    authors: Buccianti G,Lorenz M,Cresseri D,Bianchi ML,Valenti G,Cicchetti F,Francucci BM

    更新日期:1993-01-01 00:00:00

  • Update on role of direct renin inhibitor in diabetic kidney disease.

    abstract:BACKGROUND:Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease (ESRD). Renin-angiotensin-aldosterone system (RAAS) plays a critical role in the development of DKD with angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) being the mainstay of treatment. System...

    journal_title:Renal failure

    pub_type: 杂志文章,评审

    doi:10.3109/0886022X.2014.900425

    authors: Dhakarwal P,Agrawal V,Kumar A,Goli KM,Agrawal V

    更新日期:2014-07-01 00:00:00

  • Polyneuropathy due to cyclosporine A in patients with renal transplantation: a case report.

    abstract:BACKGROUND:Calcineurin inhibitor cyclosporine A (CsA) is a potent immunosuppressive agent. The side effects of CsA include nephrotoxicity, hypertension, hypertrichosis, infection, hyperpotassemia, and, to a lower extent, neuropathy. OBJECTIVES:In this case report, we aimed to present a renal transplant patient with po...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2011.573893

    authors: Sayin R,Soyoral YU,Erkoc R

    更新日期:2011-01-01 00:00:00

  • Bone mineral density in patients on maintenance hemodialysis and effect of chronic hepatitis C virus infection.

    abstract:OBJECTIVE:To determine the prevalence of osteopenia and osteoporosis in HD patients at our center; to investigate whether HCV infection affects BMD in hemodialysis patients; to test for correlations between bone mineral density (BMD) and clinical and laboratory parameters in this population. SUBJECTS AND METHODS:The s...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1081/jdi-120038501

    authors: Yücel AE,Kart-Köseoglu H,Isiklar I,Kuruinci E,Ozdemir FN,Arslan H

    更新日期:2004-03-01 00:00:00

  • Nutritional status in stage V dialyzed patient versus CKD patient on conservative therapy across different economic status.

    abstract:BACKGROUND:This aim of this multi-centric cross-sectional study was to assess the nutritional status in Indian chronic kidney disease (CKD) patients and to compare the nutritional indicators between stage 5 dialyzed (CKD-D) patients below the poverty line (BPL), and stage 3-4 non-dialyzed (CKD-ND) patients above (APL) ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2013.872570

    authors: Vijayan M,Abraham G,Alex ME,Vijayshree N,Reddy Y,Fernando E,Mathew M,Nair S,Yuvaraj A

    更新日期:2014-04-01 00:00:00

  • Efficacy comparison of atorvastatin versus rosuvastatin on blood lipid and microinflammatory state in maintenance hemodialysis patients.

    abstract:INTRODUCTION:To investigate the effect of Atorvastatin (ATO) and Rosuvastatin (ROS) on blood lipid, high sensitivity CRP (hs-CRP), interleukin-6 (IL-6), albumin (ALB), prealbumin (PA), and transferring (TF) in maintenance hemodialysis (MHD) patients. METHODS:Eighty MHD patients were enrolled and divided into two group...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2016.1256309

    authors: Tian J,Hou X,Hu L,Chen T,Wu K,Cai C,Bai X

    更新日期:2017-11-01 00:00:00

  • Classic heat stroke in a case of simple hypohydrosis with "bad prognostic indicators" but a remarkable recovery.

    abstract::Heat stroke occurs in the desert area of Saudi Arabia quite frequently and manifest in different patterns including coagulopathy. Frequently encountered complications include renal or hepatic failure, rhabdomyolysis, acute respiratory distress syndrome (ARDS), disseminated intravascular coagulation (DIC), and seizure....

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1081/jdi-100107370

    authors: Sinha AK,Ghacha R,Youmbissi JT,Khursany IA

    更新日期:2001-09-01 00:00:00

  • The role of prolidase activity in the diagnosis of uremic bone disease.

    abstract::The derangements in bone metabolism in patients with chronic renal failure (CRF) are summarized as uremic bone disease (UBD). In this study, we planned to determine the serum prolidase to compare it with the other biochemical markers. This study was performed on 44 patients (19 females, 25 males, mean age = 56.8 +/- 1...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220600577726

    authors: Evrenkaya TR,Atasoyu EM,Kara M,Unver S,Gultepe M

    更新日期:2006-01-01 00:00:00

  • Leukocyte involvement in renal reperfusion-induced liver damage.

    abstract:BACKGROUNDS/AIMS:Renal ischemia-reperfusion (IR) induces organ damage in remote organs. The aim of this study was to assess the role of leukocytes in the induction of liver damage after renal IR injury. METHODS:Inbred mice were subjected to either sham operation or bilateral renal IR injury (60 min ischemia followed b...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2010.541585

    authors: Khastar H,Kadkhodaee M,Sadeghipour HR,Seifi B,Hadjati J,Delavari F,Soleimani M

    更新日期:2011-01-01 00:00:00