Lysosomal iron accumulation in diabetic nephropathy.

abstract：:While the fractional excretion of solutes have long been considered excellent research tools to investigate tubular physiology, their clinical use has become common over the last 40 years in the diagnoses of many disorders; however, none have reached the clinical utility of the fractional excretion of sodium in the ab...

journal_title：Renal failure

authors： Diskin CJ,Stokes TJ,Dansby LM,Radcliff L,Carter TB

更新日期：2010-01-01 00:00:00

abstract：:Retroperitoneal fibrosis (RF) is a clinical entity characterized by the progressive proliferation of connective tissue that rarely forms a mass involving the periaortic area of the abdomen, which may be idiopathic as well as a result of an inflammatory process after aneurysmal dilatation of the aorta. This fibrotic ti...

journal_title：Renal failure

authors： Dişel U,Alpay NR,Paydas S

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:To explore the capacity of mutant lactobacilli to remove creatinine (Cr) and urea nitrogen (UN) via the gastrointestinal tract and its effects on renal pathology in the 5/6 nephrectomized rat model of chronic renal failure. METHODS:Sixty Sprague-Dawley rats were randomly divided into a Sham group, a Model g...

journal_title：Renal failure

authors： Wang F,Jiang YS,Liu F

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:This study was designed to investigate whether 3-amino benzamide (3-AB), a poly (ADP-ribose) polymerase (PARP) inhibitor, has a protective effect on kidney injury induced by renal ischemia/reperfusion (I/R) by decreasing oxidative and nitrosative stress on renal dysfunction and injury. MATERIALS AND METHO...

journal_title：Renal failure

authors： Oztas E,Guven A,Turk E,Uysal B,Akgul EO,Cayci T,Ersoz N,Korkmaz A

更新日期：2009-01-01 00:00:00

abstract：:Increased vascular calcification and oxidative stress are considered as extra renal risk factors at the pathogenesis cardiovascular events in chronic kidney disease (CKD). We investigated matrix Gla protein (MGP) (T-138C, Glu60X, Thr83Ala) and Klotho (Cys370Ser) gene polymorphisms, serum MGP levels, and oxidative stre...

journal_title：Renal failure

authors： Karsli Ceppioğlu S,Yurdun T,Canbakan M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:An increased red blood cell (RBC) phosphatidylserine (PS) exposure in uremic patients was found that could promote macrophage recognition and decrease RBC survival time. Furthermore, a reduced red cell life span was found to contribute anemia in patients with renal failure. It is therefore possible to hypoth...

journal_title：Renal failure

authors： Bi SH,Cheng LT,Wang T

更新日期：2006-01-01 00:00:00

abstract：:Acute renal failure secondary to ischemia/reperfusion (I/R) injury is associated with significant mortality and morbidity. Aminoguanidine (AG), an inducible nitric oxide synthase inhibitor with antioxidant properties, has been reported beneficial in renal I/R injury. The aim of the present study was to investigate the...

journal_title：Renal failure

authors： Onem Y,Ipcioglu OM,Haholu A,Sen H,Aydinoz S,Suleymanoglu S,Bilgi O,Akyol I

更新日期：2009-01-01 00:00:00

abstract：:Behçet's disease is a chronic systemic vasculitis with unknown etiology characterized by recurrent oral and genital ulcerations, ocular inflammation,having manifestations related to the skin and joints. Neurologic, pulmonary and gastrointestinal findings can also be observed during the course of the disease. In this r...

journal_title：Renal failure

authors： Nadir I,Gültekin F,Yönem O,Yildiz E

更新日期：2003-03-01 00:00:00

abstract：:Nontraumatic rhabdomyolysis is an important but under-recognized cause of acute renal failure. In alcoholics, rhabdomyolysis most frequently develop following muscle necrosis during alcohol-induced coma, but has also been described rarely in those without prolonged coma or seizures. We describe a patient who developed...

journal_title：Renal failure

authors： Muthukumar T,Jha V,Sud A,Wanchoo A,Bambery P,Sakhuja V

更新日期：1999-09-01 00:00:00

abstract：:This report describes a patient who developed acute rhabdomyolysis and acute renal failure following the application of MAST trousers associated with an overdose of diflunisal. This association has not previously been reported. ...

journal_title：Renal failure

authors： Pilmore H,Walker RJ

更新日期：1993-01-01 00:00:00

abstract：:To evaluate the efficacy of Silodosin as a medical expulsive therapy of ureteral stones, we searched PubMed, EMBASE, the Cochrane Library, and CBM up to June 2015. All randomized controlled trials (RCTs) were identified in which patients were randomized to receive Silodosin versus placebo or other therapies for ureter...

journal_title：Renal failure

authors： Ding H,Ning Z,Dai Y,Shang P,Yang L

更新日期：2016-10-01 00:00:00

abstract：:Aldosterone is reported to promote fibrosis of multiple organs. Recent studies showed that Na+-H+ exchanger isoform 1 (NHE1) was involved in mineralocorticoid-induced tissue fibrosis. The present study examined the role of NHE1 in aldosterone-induced glomerulosclerosis in rats. SD male rats were subjected to 5/6 nephr...

journal_title：Renal failure

authors： Zhang M,Chen J,Liu S,You L,Lin S,Gu Y

更新日期：2009-01-01 00:00:00

abstract：:We present a patient with AL amyloidosis who had an autologous stem cell transplant (ASCT) over 9 years ago. She has since then developed slowly progressive renal insufficiency and the nephrotic syndrome. Hematologic evaluation has failed to identify recurrent disease and a renal biopsy demonstrated extensive amyloid ...

journal_title：Renal failure

authors： Rifkin SI,Weinstein SS

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is associated with markedly increased cardiovascular (CV) risk. This increase is not fully explained by traditional CV risk factors but may in part be mediated by nontraditional risk factors, such as inadequate vitamin D (vit D) levels and insulin resistance (IR). Although IR is ...

journal_title：Renal failure

authors： Lai S,Coppola B,Dimko M,Galani A,Innico G,Frassetti N,Mariotti A

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Gastrointestinal complications are frequent in patients with renal disease and are responsible for substantial morbidity and mortality among these patients in developing countries. Many times, these patients are subjected to endoscopic evaluation and mucosal biopsies are taken for definitive diagnosis. This ...

journal_title：Renal failure

authors： Thomas R,Panackal C,John M,Joshi H,Mathai S,Kattickaran J,Iqbal M

更新日期：2013-01-01 00:00:00

abstract：:We investigated the mechanism of impaired serum opsonic activity in patients suffering from chronic renal failure (CRF). Prehemodialysis pooled serum from CRF patients was fractionated using Sephadex G-50 gel chromatography, and the effects of the obtained fractions on serum opsonic activity were examined using lumino...

journal_title：Renal failure

authors： Kikuchi T,Nigawara K,Sugawara K,Nakaji S,Abe T,Satoh H

更新日期：1997-01-01 00:00:00

abstract：:Objective The objective of this study is to explore the efficacy and safety of mizoribine (MZR) in treating nephrotic syndrome patients afflicted with hepatitis B virus (HBV). Methods The present study included 36 nephrotic syndrome patients accompanied with HBV infection. A draft of MZR (150-200 mg/d), methylpredniso...

journal_title：Renal failure

authors： Liu J,Zhang K,Ji Y,Zhang W,Li W,Yong Q,Wang J,Sun J,Zhang H

更新日期：2016-06-01 00:00:00

abstract：UNLABELLED:Contrast-induced nephropathy (CIN) is the third leading cause of acute kidney injury (AKI) in hospitalized patients. Diabetes mellitus remains a consistent independent predictor of contrast nephropathy. AIM:To determine frequency and predictors of contrast-induced nephropathy after cardiac catheterization i...

journal_title：Renal failure

authors： Sany D,Refaat H,Elshahawy Y,Mohab A,Ezzat H

更新日期：2014-03-01 00:00:00

abstract：:Compared to prior studies which frequently pinpoint the impairment of one parameter or function, this paper reports for the first time an extensive characterization of the toxic effects of gentamicin in a single model of primary cultured rabbit proximal tubule cells developed without insulin and glucose. Biochemical, ...

journal_title：Renal failure

authors： Monteil C,Leclere C,Fillastre JP,Morin JP

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is associated with muscle excess fatigue and diminished maximal whole body oxygen consumption, which in part could be depended on poor muscle microcirculatory network. The aim of this study was to assume the influence of different stages of CKD on microcirculation vessels in func...

journal_title：Renal failure

authors： Flisiński M,Brymora A,Elminowska-Wenda G,Bogucka J,Walasik K,Stefańska A,Odrowaz-Sypniewska G,Manitius J

更新日期：2008-01-01 00:00:00

abstract：:Renal biopsy data indicate that tubular epithelial cells serve as a reservoir for HIV-1 infection. We studied the effect of HIV-1 gp120 envelope gene expression on tubular cell apoptosis. HIV-1 gp120 was expressed in a lentiviral vector pHR-CMV-IRES2-EGFP-DeltaB. This plasmid construct was used to produce pseudotyped ...

journal_title：Renal failure

authors： Vashistha H,Husain M,Kumar D,Singhal PC

更新日期：2009-01-01 00:00:00

abstract：:Gentamicin-induced nephrotoxicity results in necrosis of proximal tubular epithelial cells. In mammals, the injured nephron can be repaired by migration and division of surviving cells. We examined this repair process in the fresh-water goldfish, Carassius auratus. Fish were given a single intraperitoneal injection of...

journal_title：Renal failure

authors： Reimschuessel R,Williams D

更新日期：1995-03-01 00:00:00

abstract：:This study was aimed to investigate the therapeutic potential of coenzyme Q10 and its combination with sitagliptin in experimentally induced diabetic nephropathy. The diabetic rats were treated with coenzyme Q10 or sitagliptin and their concomitant administration. Various parameters of renal function like serum creati...

journal_title：Renal failure

authors： Maheshwari R,Balaraman R,Sen AK,Shukla D,Seth A

更新日期：2017-11-01 00:00:00

abstract：:Neutrophil-lymphocyte ratio (NLR) is a marker of systemic inflammation that has been shown to predict mortality in patients with malignancies, ischemic heart disease and peripheral vascular disease. Its prognostic value in hemodialysis patients is unclear. The aims of this study were to: (i) explore the relationship b...

journal_title：Renal failure

authors： Neuen BL,Leather N,Greenwood AM,Gunnarsson R,Cho Y,Mantha ML

更新日期：2016-01-01 00:00:00

abstract：AIMS:The use of hemodialysis temporary dual-lumen catheters is often complicated by infections, which may be a significant cause of death among patients with end stage renal disease (ESRD). The aim of this study was to assess the incidence of bacteremia and bacterial colonization related to non-tunneled, non-cuffed, du...

journal_title：Renal failure

authors： de Freitas LW,Neto MM,Nascimento MM,Figueiredo JF

更新日期：2008-01-01 00:00:00

abstract：:A 68-year-old male presented with acute myeloid leukemia, renal failure, hypokalemia, and enlarged kidneys on renal ultrasound. Renal biopsy revealed massive leukemic infiltration of the kidney. After systemic chemotherapy, the patient developed tumor lysis syndrome followed by a phase of proximal tubule dysfunction p...

journal_title：Renal failure

authors： Rüger W,Kruip MJ,Betjes MG

更新日期：2009-01-01 00:00:00

abstract：:Anticoagulants are commonly used to prolong circuit life during continuous hemofiltration. However, a clear correlation between routinely performed blood coagulability tests and circuit life has not been demonstrated. This lack of correlation may derive from the limited ability of such tests to describe the likelihood...

journal_title：Renal failure

authors： Baldwin I,Tan HK,Bridge N,Bellomo R

更新日期：2000-05-01 00:00:00

abstract：:Although sudden sensorineural hearing loss (SSNHL) affects chronic kidney disease (CKD) patients more frequently than non-CKD patients, few reports have described SSNHL in dialysis patients. We aimed to review the characteristics of SSNHL in chronic dialysis patients and evaluate treatment responses to steroid therapy...

journal_title：Renal failure

authors： Kang SM,Lim HW,Yu H

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:The present study investigated whether hemodialysis (HD) patients exhibit future memory impairment (PM; the capability of remembering to perform expected future actions) and exploring relevant factors of PM task performance. METHODS:Sixty HD patients and 60 healthy controls matched by age are enrolled in the...

journal_title：Renal failure

authors： Wang B,Li M,Tang F,Wang Y,Han Y,Lu W,Zhang L,Zhang L,Ni W,Zhang L,Zhang L

更新日期：2020-11-01 00:00:00

abstract：:The case records of 75 patients who had systemic lupus erythematosus (SLE) and renal involvement on renal histology were reviewed. There were 70 females and 5 males, with a ratio of 14:1. The majority of the patients were in their second and third decades of life. SLE nephritis was distinctly uncommon in patients belo...

journal_title：Renal failure

authors： Williams W,Shah D

更新日期：1990-01-01 00:00:00