Abstract：
:Mucoceles can occur in the oral cavity, appendix, bladder, paranasal sinuses, and lacrimal sac. In the oral cavity, mucoceles arise from pathological alterations in the minor salivary gland ducts. In this study, we aimed to histologically reevaluate cases of oral mucoceles to identify possible variants. A total of 667 slides containing tissue sections stained with hematoxylin and eosin diagnosed as a phenomenon of mucus extravasation were analyzed under light microscopy by 4 previously trained examiners. In 128 cases (19.1%), 1 or more histopathological changes were identified. Twenty cases (2.9%) exhibited collagenous globular structures compatible with myxoglobulosis. In 30 cases (4.49%), dissociation of collagen fibers after mucin extravasation was observed. Fifty-four cases (8.09%) exhibited papillary synovial metaplasia-like change, and 32 (4.79%) showed a significant reduction in the lumen of the cavity due to large papillae. Twenty cases (2.9%) were compatible with superficial mucoceles, and in 11 cases (1.64%), the foamy macrophages showed an unusual solid arrangement, known as clear cell change. It is essential to recognize the possible histopathological changes in oral mucoceles to avoid diagnostic pitfalls.
journal_name
Ann Diagn Patholjournal_title
Annals of diagnostic pathologyauthors
de Brito Monteiro BV,Bezerra TM,da Silveira ÉJ,Nonaka CF,da Costa Miguel MCdoi
10.1016/j.anndiagpath.2016.02.001subject
Has Abstractpub_date
2016-04-01 00:00:00pages
44-6eissn
1092-9134issn
1532-8198pii
S1092-9134(15)30076-9journal_volume
21pub_type
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journal_title：Annals of diagnostic pathology
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journal_title：Annals of diagnostic pathology
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journal_title：Annals of diagnostic pathology
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