Abstract:
BACKGROUND:Recent studies have analyzed the potential of advanced endoscopic imaging techniques for differentiating hyperplastic and adenomatous colorectal lesions. Latest endoscopic resection techniques now also allow for treatment of more advanced staged lesions including treatment of early cancerous lesions. AIMS:To assess the potential of the i-scan technology to differentiate between adenomatous polyps and advanced staged neoplasia. METHODS:Consecutive patients undergoing colonoscopy at a tertiary referral center were included. After a dedicated training, participating endoscopists underwent a review of 298 unknown images of colonic lesions to assess colorectal lesion histology. RESULTS:Overall accuracy for prediction of advanced staged neoplasia was 92.2% (sensitivity: 94.2%, specificity 90.9%). The positive and negative predictive values were calculated as 87.5% and 95.9%, respectively. The κ-value for differentiating adenomatous polyps and advanced staged neoplasia was 0.8193 (0.7894 to 0.8492). Intraobserver agreement was calculated with a κ-value of 0.9301 (0.8875 to 0.9727). CONCLUSIONS:Accurate interpretation of i-scan images for prediction of advanced colorectal neoplasia can successfully be performed even by nonexpert endoscopists with a high overall accuracy and excellent interobserver agreements.
journal_name
J Clin Gastroenteroljournal_title
Journal of clinical gastroenterologyauthors
Albrecht H,Nägel A,Tasdelen H,Rath T,Grauer M,Vieth M,Neurath MF,Neumann Hdoi
10.1097/MCG.0000000000000527subject
Has Abstractpub_date
2016-11-01 00:00:00pages
e91-e94issue
10eissn
0192-0790issn
1539-2031journal_volume
50pub_type
杂志文章,多中心研究abstract:BACKGROUND:The impact of methicillin-resistant Staphylococcus aureus (MRSA) colonization of percutaneous endoscopic gastrostomy (PEG) sites on morbidity and mortality is uncertain. AIM:We investigated the impact of known prior MRSA colonization on the incidence of symptomatic PEG site wound infection and mortality. M...
journal_title:Journal of clinical gastroenterology
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abstract::Eosinophilic esophagitis (EoE) is a chronic, immune/antigen-mediated, esophageal disease characterized by esophageal dysfunction and eosinophilic inflammation, manifested mainly as dysphagia and frequent food impaction. EoE is recognized into the spectrum of food allergy, but food sensitization studies used not to be ...
journal_title:Journal of clinical gastroenterology
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