A Survival Score for Patients Receiving Stereotactic Radiosurgery Alone for Brain Metastases from Breast Cancer.

abstract：AIM:This retrospective observational study evaluated the role of hypo-fractionated stereotactic radiotherapy (SRT) in patients with oligo-progressive metastatic renal cell carcinoma (mRCC) treated with first-line oral tyrosine kinase inhibitors (TKI). Data on local control, delay of further progression, and safety are ...

journal_title：Anticancer research

authors： Gebbia V,Girlando A,DI Grazia A,Fazio I,Borsellino N,Piazza D,Serretta V,Pergolizzi S,Pontoriero A,Firenze A,Valerio MR

更新日期：2020-12-01 00:00:00

abstract：AIM:To evaluate factors associated with the selection of first-line bevacizumab plus chemotherapy and clinical response in HER2-negative metastatic breast cancer (MBC) in clinical practice in Spain. PATIENTS AND METHODS:All consecutive adult female patients with HER2-negative MBC who had received first-line bevacizuma...

journal_title：Anticancer research

authors： Manso L,Palomo AG,Pérez Carrión R,Cassinello J,Gallegos Sancho I,Chacón López-Muñiz I,Olier C,Fernández-Aramburo A,Llorca C,González X,Llorente R,Torregrosa D,Álvarez I,Gálve E,Bueno C,Garau I,García MJ,González-Santiag

更新日期：2015-12-01 00:00:00

abstract：:Metastatic pancreatic malignant melanoma is considered to be a highly aggressive neoplasm, and only few metastasectomies for lesions originating from the skin or the ocular region have been reported. We report a case of resection of pancreatic metastasis of malignant melanoma originating from the nasal cavity. An isol...

journal_title：Anticancer research

authors： Sugimoto M,Gotohda N,Kato Y,Takahashi S,Kinoshita T,Shibasaki H,Kojima M,Ochiai A,Zenda S,Akimoto T,Konishi M

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Because treatment of advanced pancreatic cancer is often unsuccessful, early detection is important. Codon 12 c-Ki-ras mutations have been found in 80-90% of pancreatic cancer cases and are a potential early marker for pancreatic cancer, but obtaining tissue or fluid for analysis can be difficult. We therefo...

journal_title：Anticancer research

authors： Abbruzzese JL,Evans DB,Raijman I,Larry L,King T,Leach SD,Frazier ML

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:In 1979, Montgomery and Asberg introduced an inventory for screening of depression. To our knowledge, the associations between the MADRS and the risk of breast cancer (BC) are rarely considered together in a prospective study. PATIENTS AND METHODS:In an extension of the Kuopio Breast Cancer Study, 115 women...

journal_title：Anticancer research

authors： Eskelinen M,Ollonen P

更新日期：2011-03-01 00:00:00

abstract：:The expression of p53 and mdm-2 proteins was analysed in parrafin sections from 39 cases of Hodgkin's disease (HD) and compared to the presence of Epstein-Barr Virus (EBV). P53 protein was found in Hodgkin and Reed-Sternberg (HRS) cells in 12/39 cases. Mdm-2 protein was found in HRS cells in 10/39 cases. EBV-encoded E...

journal_title：Anticancer research

authors： Tzardi M,Kouvidou C,Panayiotides I,Koutsoubi K,Stefanaki K,Giannikaki E,Darivianaki K,Zois M,Eliopoulos G,Kakolyris S,Delides G,Rontogianni D,Kanavaros P

更新日期：1996-09-01 00:00:00

abstract：:Grape seed extracts were more cytotoxic than grape peel extracts. Methanol and 70% methanol extracts of grape seed selectively killed two human oral tumor cell lines, more efficiently than human gingival fibroblasts. ESR spectroscopy revealed that these extracts produced radicals under alkaline conditions and enhanced...

journal_title：Anticancer research

authors： Shirataki Y,Kawase M,Saito S,Kurihara T,Tanaka W,Satoh K,Sakagami H,Motohashi N

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Biodegradable loaded systems are promising devices for controlled and sustained release of anticancer drugs to brain tumours. We investigated the influence of drug-release profiles of 5-fluorouracil-loaded microspheres designed for the treatment of malignant gliomas. MATERIALS AND METHODS:2.5 mg 5-FU delive...

journal_title：Anticancer research

authors： Roullin VG,Lemaire L,Venier-Julienne MC,Faisant N,Franconi F,Benoit JP

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND/AIM:New anticancer drugs are usually tested on cancer cells in culture in a standard medium. We stimulated immune polynuclear cells by lipopolysaccharides to obtain an enriched medium (EM) containing inflammatory cytokines more closely reflecting the tumor microenvironment and tested a rhenium-diselenium (Re...

journal_title：Anticancer research

authors： Veena V,Harikrishnan A,Lakshmi B,Khanna S,Desmaele D,Collery P

更新日期：2020-04-01 00:00:00

abstract：:Bisphosphonates are strong inhibitors of osteoclastic bone resorption in both benign and malignant bone diseases. The nitrogen-containing bisphosphonates (N-BPs) have strong cytotoxicity via inhibition of protein prenylation in the mevalonate pathway, and also demonstrate direct cytostatic and proapoptotic effects on ...

journal_title：Anticancer research

authors： Tanaka T,Kawashima H,Ohnishi K,Matsumura K,Yoshimura R,Matsuyama M,Kuratsukuri K,Nakatani T

更新日期：2009-04-01 00:00:00

abstract：:Hypoxia, a condition of reduced oxygen concentration, is observed in many physiological and pathophysiological states. However, there is rather limited information regarding hypoxic effects in the processes of immortalization and senescence of human cells. Here, the effects of hypoxia induced by either 1.5% O2, or by ...

journal_title：Anticancer research

authors： Poulios E,Trougakos IP,Gonos ES

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND/AIM:Failure of cancer chemotherapy caused by multidrug resistance (MDR) of tumor cells is mediated by ABC transporters that reduce the uptake of cytotoxic agents. Similar transporters are responsible for amyloid clearance in nerve cells in Alzheimer's disease (AD). The aim of this study was to compare the bi...

journal_title：Anticancer research

authors： Molnar J,Ocsovszki I,Pusztai R

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND/AIM:We evaluated the usefulness of reverse transcription-polymerase chain reaction (RT-PCR) for detecting anaplastic lymphoma kinase (ALK) translocations using cytology samples from lung cancer patients. MATERIALS AND METHODS:We analyzed ALK translocations by RT-PCR in cytology samples from lung cancer pati...

journal_title：Anticancer research

authors： Nakamichi S,Seike M,Miyanaga A,Chiba M,Matsuda K,Kobayashi K,Takahashi A,Takeuchi S,Minegishi Y,Kubota K,Gemma A

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND/AIM:The aim of this study was to investigate the effects of the macrophage colony-stimulating factor (M-CSF) receptor antagonist on hepatic carcinogenesis in mice. MATERIALS AND METHODS:Mice were injected with diethylnitrosamine (DEN) and treated with M-CSF receptor antagonist GW2580 (GW) or a saline vehicl...

journal_title：Anticancer research

authors： Akazawa Y,Kono H,Hara M,Furuya S,Nakata Y,Wakana H,Fukushima H,Sun C,Fujii H,Ichikawa D

更新日期：2019-09-01 00:00:00

abstract：:A consecutive series of 128 breast cancer patients detected by breast screening were enrolled in this study to analyze their age-dependent characteristics. They were classified into three groups; 40 years or less (young): 26 patients, 41-55 years (middle-aged): 67 patients and 56 years or over (old): 35 patients. The ...

journal_title：Anticancer research

authors： Takei H,Iino Y,Horiguchi J,Maemura M,Koibuchi Y,Horii Y,Nagaoka H,Matsumoto H,Ishikita T,Yokoe T,Morishita Y

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Women with recurrent ovarian cancer have a poor prognosis and short survival. However, some women are long-term survivors and it is unclear whether they share specific common characteristics. CASE REPORT:We present the case of a 63-year-old woman with histologically-proven recurrent ovarian cancer and a sur...

journal_title：Anticancer research

authors： Hilal Z,Schultheis B,Hartmann F,Dogan A,Cetin C,Krentel H,Schiermeier S,Tempfer CB

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND/AIM:Patients with obstructive jaundice due to cancer of the pancreatic head often undergo preoperative endoscopic biliary drainage (EBD). The aim of the study was to evaluate the long-term impact of preoperative EBD following pancreaticoduodenectomy (PD) for pancreatic ductal adenocarcinoma. PATIENTS AND ME...

journal_title：Anticancer research

authors： Furukawa K,Shiba H,Shirai Y,Horiuchi T,Iwase R,Haruki K,Fujiwara Y,Misawa T,Yanaga K

更新日期：2015-09-01 00:00:00

abstract：:In order to determine the efficacy of liposomal encapsulated daunorubicin (DaunoXome; DNX) in chronic Iymphocytic leukaemia, the sensitivities of cells from 10 patients with this disease were assessed and compared with that of free drug using the MTT assay. There was a marked variation in effect between patients for b...

journal_title：Anticancer research

authors： Sargent JM,Elgie AW,Williamson CJ,Lewandowicz GM,Taylor CG

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Pleomorphic rhabdomyosarcomas of the uterus, mainly occurring in postmenopausal women with leading symptoms of vaginal bleeding and abdominal pain, are very rare malignant tumors of the female genital tract. Due to the inefficiency of the adjuvant therapy, the outcome remains poor in the majority of the repo...

journal_title：Anticancer research

authors： Alavi S,Eckes L,Kratschell R,Taube ET,Rosseck F,Wieners G,Sehouli J

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) have been linked to a number of cancer types including breast cancer. The rate of brain metastases is 10-30% in patients with advanced breast cancer which is associated with poor prognosis. The potential application of miRNAs in the diagnostics and therapeutics of breast cancer with brain ...

journal_title：Anticancer research

authors： Li Z,Peng Z,Gu S,Zheng J,Feng D,Qin Q,He J

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:One of the major changes in the new TNM classification (5th edition, 1997) for gastric cancer was made in the classification of N category: the 5th edition employs the number of involved nodes and a minimum of 15 examined nodes is required for N0 classification. The validity of the new TNM classification was...

journal_title：Anticancer research

authors： Nio Y,Yamasawa K,Yamaguchi K,Itakura M,Omori H,Koike M,Kitamura Y,Tsuji M,Endo S,Ogo Y,Yano S,Sumi S

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND/AIM:Although insulin-like growth factor-1 (IGF-1) is well-implicated in cancer biology, the potential roles of IGF-1 variants in different types of cancer are largely unknown. The aim of the present study was to in vitro characterize several human cancers for their IGF-1 variant expression patterns. MATERIA...

journal_title：Anticancer research

authors： Christopoulos PF,Philippou A,Koutsilieris M

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Cancer-related acute disseminated intravascular coagulation (DIC) is uncommon, but it is a severe complication resulting in a very dismal prognosis. Choosing the appropriate chemotherapy agents to treat the underlying cancer and stop the acute DIC process effectively, while avoiding chemotherapy-induced myel...

journal_title：Anticancer research

authors： Lin PH,Lu YS,Lin CH,Chang DY,Huang CS,Cheng AL,Yeh KH

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:A gastrostomy feeding tube is one method for long-term feeding support in patients undergoing radio(chemo)therapy for head and neck cancer (HNC). The aim of this study was to analyze the safety of prophylactic gastrostomy tube placement and usage in HNSCC patients. PATIENTS AND METHODS:HNC patients undergoi...

journal_title：Anticancer research

authors： Sieron HL,Eberle F,Gress TM,Mahnken AH,Wiegand S

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND/AIM:Small cell lung cancer (SCLC) is still a deadly type of cancer for which there are few effective therapeutic strategies. Development of a new molecule targeting agent is urgently desired. Previously we showed that recombination signal binding protein for immunoglobulin-kappa-J region (RBPJ) and mastermin...

journal_title：Anticancer research

authors： Onishi H,Ichimiya S,Yanai K,Umebayashi M,Nakamura K,Yamasaki A,Imaizumi A,Nagai S,Murahashi M,Ogata H,Morisaki T

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND/AIM:Few data are available on the utility of definitive radiation therapy (RT) for pediatric craniopharyngioma. This study sought to evaluate practice patterns and patient outcomes using the Surveillance Epidemiology and End Results database from 2004-2014. MATERIALS AND METHODS:Overall survival (OS) was co...

journal_title：Anticancer research

authors： Hill TK,Baine MJ,Verma V,Alam M,Lyden ER,Lin C,Connolly EP,Zhang C

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND/AIM:Intensity-modulated radiation therapy (IMRT) is a form of radiation therapy that allows accurate irradiation with reduced damage to surrounding tissues. Here, we analyzed borderline-resectable pancreatic cancer (BRPC) with arterial abutment (BR-A) patients with IMRT as neoadjuvant therapy and performed c...

journal_title：Anticancer research

authors： Masui T,Takaori K,Anazawa T,Sato A,Nakano K,Uchida Y,Yogo A,Goto Y,Matsumoto S,Kodama Y,Kanai M,Isoda H,Mizumoto M,Kawaguchi Y,Shibuya K,Itasaka S,Uemoto S

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND/AIM:Metabolomics is widely used for biomarker discovery, but conventional mass-spectrometry extraction procedures lose the spatial localization of metabolites. In this study, we directly analyzed breast carcinoma tissues embedded in frozen tissue microarrays (fTMAs) using MALDI mass-spectrometry imaging (MAL...

journal_title：Anticancer research

authors： Torata N,Kubo M,Miura D,Ohuchida K,Mizuuchi Y,Fujimura Y,Hayakawa E,Kai M,Oda Y,Mizumoto K,Hashizume M,Nakamura M

更新日期：2018-07-01 00:00:00

abstract：:Adjuvant radioimmunotherapy (RIT) for human colonic cancer was performed in a nude rat model of experimental liver metastases. Thirty-three rats were injected intraportally through a mesenteric vein with 5 x 10(6) cells from the human colonic cancer cell line LS174T. Within half an hour, 20 MBq (n = 2), 75 MBq (n = 5)...

journal_title：Anticancer research

authors： Mahteme H,Lövqvist A,Graf W,Lundqvist H,Carlsson J,Sundin A

更新日期：1998-03-01 00:00:00

abstract：:The therapeutic opportunities for an improved management of malignant bone disease are currently extensively studied. The conventional management of symptomatic bone lesions in patients with advanced cancer involves various combinations of local and systemic standard anticancer therapies and the symptomatic treatment ...

journal_title：Anticancer research

authors： Lüftner D,Henschke P,Possinger K

更新日期：2007-07-01 00:00:00