Abstract:
PURPOSE:To study the effect of deep sclerectomy (DS) in primary open-angle glaucoma (POAG) and exfoliative glaucoma (EXG). METHODS:We retrospectively analyzed the intraocular pressure (IOP)-lowering effect of DS in 235 consecutive eyes. Eyes were divided into 2 groups according to glaucoma subtype: POAG (127 eyes) and EXG (108 eyes). Postoperative IOP was the main outcome measurement. We recorded complete and qualified surgical success, need for YAG-laser goniopuncture, and need for postoperative glaucoma medication. We studied factors related to outcome of surgery in a Cox regression model. RESULTS:In the POAG group, the mean (SD) IOP decreased from 22.6 (5.1) mm Hg preoperatively to 16.8 (7.5) mm Hg, with qualified success achieved in 70% of eyes. Postoperatively, 57% were without medication. In the EXG group, IOP decreased from 25.5 (6.5) mm Hg preoperatively to 16.5 (7.8) mm Hg postoperatively, with qualified success achieved in 66% of eyes. Postoperatively, 50% were without medication. Decrease in IOP was statistically significant in both groups (p<0.001). In the POAG group, 12%, and in the EXG group, 24% needed a reoperation in the follow-up period (p = 0.037). In the Cox regression model, 1 week IOP between 2 and 14 mm Hg without medication lowered the hazard rate of losing complete success by 34% (p = 0.031) and the hazard rate of losing qualified success by 54% (p = 0.004). CONCLUSIONS:The IOP 1 week postoperatively seems to be a prominent indicator of surgical success. Deep sclerectomy is effective in reducing IOP in POAG and EXG subgroups, with reoperations more common in EXG eyes.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Suominen SM,Harju MP,Vesti ETdoi
10.5301/ejo.5000762subject
Has Abstractpub_date
2016-11-04 00:00:00pages
568-574issue
6eissn
1120-6721issn
1724-6016pii
EA6A864B-9C22-4B54-A306-6FFB0B95496Ejournal_volume
26pub_type
杂志文章abstract:BACKGROUND/OBJECTIVES:The aim of this article was to study the lower punctum parameters in patients with acquired punctal stenosis using spectral-domain anterior segment optical coherence tomography. SUBJECTS/METHODS:This was a prospective nonrandomized study that included two groups. Group 1 was composed of 32 puncta...
journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究
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更新日期:2018-07-01 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2008-07-01 00:00:00
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journal_title:European journal of ophthalmology
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doi:10.1177/112067211002000109
更新日期:2010-01-01 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To evaluate the long-term efficacy and safety of standard-fluence photodynamic therapy (PDT) with verteporfin using the minimum PDT spot size in patients with diffuse retinal pigment epitheliopathy (DRPE). METHODS:This is a retrospective study of 67 DRPE cases treated with PDT using a standardized minimum spot...
journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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更新日期:2013-01-21 00:00:00
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更新日期:2020-09-01 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2012-01-01 00:00:00
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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