Abstract:
PURPOSE:To compare 2 different application methods of mitomycin C (MMC) in patients undergoing trabeculectomy. METHODS:This retrospective trial compared outcomes of 191 eyes that underwent trabeculectomy with small-area (96 eyes; 50.3%) and large-area (95 eyes; 49.7%) MMC application. Main outcome measures were changes in intraocular pressure (IOP), required glaucoma medications, the frequency of complications, and postsurgical interventions. RESULTS:Within both treatment groups, a highly significant IOP reduction was seen during follow-up (p < 0.0001). Statistical analyses revealed a significant difference in IOP between both groups. Patients treated with a larger size of surface area had a higher IOP reduction within the first postoperative year. Choroidal detachment, shallow anterior chamber, and bleb leak were seen more often in the large-area group with more aggressive MMC use. In contrast, complications associated with bleb failure such as bleb scarring were higher in the small-area group. Success rate was higher in the large-area MMC application group after 12 months. CONCLUSIONS:Large-area treatment seems to be a more efficient application method of MMC during trabeculectomy.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Matlach J,Panidou E,Grehn F,Klink Tdoi
10.5301/ejo.5000287subject
Has Abstractpub_date
2013-09-01 00:00:00pages
670-7issue
5eissn
1120-6721issn
1724-6016pii
64EE018E-29F5-4C26-A964-5BED9F37012Ejournal_volume
23pub_type
杂志文章abstract:PURPOSE:To study the effects of continuous ultrasonic phacoemulsification performed with and without an anterior chamber maintainer (ACM) on corneal endothelial damage in patients with hard nuclear cataract. METHODS:Sixty eyes in 60 patients with hard nuclear cataract (grade IV), one lesion per eye, were randomly allo...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.5301/ejo.5000537
更新日期:2015-05-01 00:00:00
abstract:PURPOSE:A pilot study was carried out to evaluate the practicality, reliability, and validity of an objective structured clinical examination (OSCE) for assessing the clinical skills and abilities of specialists in ophthalmology. METHODS:Ten unfolded OSCE style, criterion referenced questions were asked to nine candid...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210601600415
更新日期:2006-07-01 00:00:00
abstract:PURPOSE:Norrie disease (ND) is a rare X-linked recessive disorder characterized by congenital blindness, which is often associated with sensorineural hearing loss and mental retardation. X-linked familial exudative vitreoretinopathy (FEVR) is a hereditary disorder characterized by an abnormality of the peripheral retin...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067219900900312
更新日期:1999-07-01 00:00:00
abstract::Cone-rod dystrophy (CORD) is one of the inherited retinal diseases that result in central visual field deterioration and decreased visual acuity (VA). In CORD patients, impaired photoreceptor cells are observed as the disruption of ellipsoid zone (EZ) on optical coherence tomography (OCT) images. In the present study,...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672121990561
更新日期:2021-01-26 00:00:00
abstract::The objectives of this study were two-fold: to identify tear histamine content and its relationship to changes in tear histaminase activity during the early (EPR) and late phases (LPR) of the allergic reaction induced by a conjunctival provocation test (CPT) and to evaluate the effects of lodoxamide on histamine relea...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1996-04-01 00:00:00
abstract::Wet age-related macular degeneration is a chronic condition culminating, in most cases, in blindness. The introduction of anti-angiogenic agents in 2006 has represented a major breakthrough in the treatment of the disease, but timely and effective treatment with regular follow-up and monitoring is mandatory to stabili...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1177/1120672120915685
更新日期:2020-07-01 00:00:00
abstract:PURPOSE:To delineate and discuss a not yet described possible ocular complication of selective intra-arterial chemotherapy (SIAC) for treatment of retinoblastoma. METHODS:A 23-month-old girl with a large unilateral retinoblastoma was treated with repeated SIAC using 5 mg melphalan between July 2010 and January 2012. C...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000393
更新日期:2014-05-01 00:00:00
abstract:PURPOSE:The purpose of this study was to assess indications and outcome of carotid Doppler ultrasound requested by ophthalmologists from an eye hospital over a period of three years. METHODS:This retrospective study was designed to analyse data for all patients referred to have carotid Doppler ultrasound from 1999 to ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2004-05-01 00:00:00
abstract:PURPOSE:To compare between mitomycin C alone, porcine extracellular matrix alone, and combined low dose mitomycin C with porcine extracellular matrix in term of efficacy and safety in phaco-trabeculectomy surgery. STUDY DESIGN:Prospective comparative. METHODS:Sixty eyes of 60 patients complaining of primary open angl...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120944339
更新日期:2021-01-01 00:00:00
abstract::Although it is now possible to significantly reduce the incidence of blindness secondary to diabetes mellitus, large numbers of diabetic patients still experience visual loss due to retinal complications of the disease. This implies that protocols for the diagnosis and treatment of diabetic retinopathy used in the var...
journal_title:European journal of ophthalmology
pub_type: 社论
doi:10.1177/112067219900900302
更新日期:1999-07-01 00:00:00
abstract:PURPOSE:To evaluate in a retrospective study the long-term usefulness of red 647 nm krypton and 670 nm diode laser for transscleral contact cyclophotocoagulation (CPC) in the treatment of therapy-resistant inflammatory glaucoma. METHODS:The authors treated 48 eyes of 38 consecutive patients (mean age 36.8 years, range...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700412
更新日期:2007-07-01 00:00:00
abstract:PURPOSE:To carry out a pilot study comparing the size of various types of metallic intraocular foreign bodies as imaged on computed tomographic (CT) scan to their actual size, and to determine the features of different types of metals on CT scan. METHODS:Metallic foreign bodies of predetermined standardized sizes were...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210901900528
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:To report management of diplopia with botulinum toxin injection in traumatic multiple ocular motor cranial neuropathies. METHODS:Alternate prism and cover measurement of deviation in different positions of gaze, examination of ductions, field of binocular single vision, and complete ocular anterior and poste...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000202
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:To analyze and compare the high performance liquid chromatography (HPLC) runs of tear proteins from diabetic (DIDRY) and non-diabetic (DRY) dry-eye patients, and healthy subjects (CTRL). The patterns were analyzed using multivariate statistical methods. METHODS:Tears (total 56 eyes: CTRL: n=16, DIDRY: n=21, an...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100105
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:To report on the microperimetric evaluation of the central visual field in a patient with retinopathy due to membranoproliferative glomerulonephritis. METHODS:The central 20 degrees visual field was evaluated using fundus-related perimetry with (Nidek MP1) microperimeter in a patient with proven membranoprolif...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210601600425
更新日期:2006-07-01 00:00:00
abstract:PURPOSE:Parry-Romberg syndrome (PRS) is a rare disease of unknown etiology and pathogenesis, characterized by progressive hemifacial atrophy. Diverse ocular manifestations were reported in association with PRS, including enophthalmos, lid retraction, blepharoptosis, restrictive strabismus, ocular motor nerve dysfunctio...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000132
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:To review the current practice of retreatment with Ozurdex injections in patients with macular edema (ME) secondary to retinal vein occlusion (RVO), and to recommend simple guidelines for Ozurdex reinjection in management of RVO. METHODS:This was a multicenter retrospective study of patients who received more ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.5301/ejo.5000376
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:To identify PAX6 mutations in patients from four Japanese families with aniridia. METHODS:Polymerase chain reaction (PCR)-single stand conformational polymorphism (SSCP) analysis (SSCA) was performed in probands of the families, and restriction analysis using MaeIII or AvaI was carried out in other affected fa...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1177/112067210001000213
更新日期:2000-04-01 00:00:00
abstract:PURPOSE:The authors wondered whether the spectrum of endophthalmitis and the type of therapy had changed. METHODS:Files of patients who were operated upon for endophthalmitis between 1988 and 2000 were retrospectively analyzed. They were divided into Group 1 (operated upon 1988 to 1994) and Group 2 (1995 to 2000). RE...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210601600217
更新日期:2006-03-01 00:00:00
abstract:PURPOSE:To survey the routine practice of consultant ophthalmic surgeons in the United Kingdom in preventing postoperative endophthalmitis following cataract surgery. METHODS:This is a cross-sectional questionnaire-based study. A questionnaire was sent to consultant ophthalmic surgeons in university teaching hospital ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1177/112067210601600306
更新日期:2006-05-01 00:00:00
abstract:PURPOSE:To evaluate anterior chamber biometry of the eyes of normal children using ultrasound biomicroscopy (UBM) and to evaluate the differences in biometry between children and adults, and before and after pupil dilation in children. METHODS:Anterior chamber depth (ACD) and trabecular-iris angle (TIA) were measured ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800405
更新日期:2008-07-01 00:00:00
abstract:PURPOSE:To report clinical findings and surgical management of 4 patients with congenital nystagmus who presented with a new or reversal of their original horizontal compensatory head posture (CHP) after Anderson-Kestenbaum (A-K) surgery. METHOD:Retrospective chart review. RESULTS:All 4 patients demonstrated a 40°-45...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2011.8356
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To investigate the clinical effects and outcomes of intravitreal injection of 4 mg of triamcinolone acetonide (IVTA) after or concomitant with macular laser photocoagulation (MP) for clinically significant macular edema (CSME). METHODS:Forty-nine eyes of 49 patients with nonproliferative diabetic retinopathy a...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1177/112067210901900418
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:During the current coronavirus (COVID-19) pandemic, some ophthalmologists across the United Kingdom (UK) have been redeployed to areas of need across the National Health Service (NHS). This survey was performed to assess aspects of this process including training & education, tasks expected, availability of ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120953339
更新日期:2020-08-27 00:00:00
abstract:PURPOSE:To assess the difference in best-corrected visual acuity (BCVA) at presentation between the first and second eye in patients with bilateral neovascular age-related macular degeneration (AMD). METHODS:We reviewed the charts of all patients who had a clinical examination for neovascular AMD at the University Eye...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000649
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:To study the correlation between final visual acuity after successful anatomic macular hole repair and features on spectral domain optical coherence tomography (SD-OCT). METHODS:Retrospective review of charts of patients who underwent macular hole surgery. Data collection included pre- and postoperative best-c...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000306
更新日期:2010-05-01 00:00:00
abstract:PURPOSE:To describe the long-term clinical course of patients with low-pressure glaucoma (LPG) and to assess the risk factors for disease progression. METHODS:The Wills Eye Glaucoma Research Center retrospectively reviewed the charts of LPG patients with documented follow-up of >8 years between 2000 and 2013. Medical ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000624
更新日期:2015-11-01 00:00:00
abstract::Purpose. To investigate the sensitivity and specificity of machine learning classifiers (MLC) and spectral domain optical coherence tomography (SD-OCT) for the diagnosis of glaucoma. Methods. Sixty-two patients with early to moderate glaucomatous visual field damage and 48 healthy individuals were included. All subjec...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000183
更新日期:2012-06-15 00:00:00
abstract:PURPOSE:To describe a case of multiorganism, drug-resistant keratitis that responded well to corneal crosslinking (CXL) treatment. METHODS:A 52-year-old man presented to our institute with a 2-month ocular history of infectious keratitis in his right eye, on topical antibacterial, antifungal, and antiprotozoan treatme...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000755
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:To determine the prevalence of symptoms of computer vision syndrome and to identify its associated factors. The secondary objective was to assess knowledge and practices related to preventing computer vision syndrome symptoms. METHODS:The data for this cross-sectional study were collected through a self-admini...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672118815110
更新日期:2020-01-01 00:00:00