Abstract:
INTRODUCTION:To assess the association between miR-200 family expression and overall survival/progression-free survival in women with ovarian cancer. MATERIAL AND METHODS:A systematic literature search, up to September 2015, in PubMed, EMBASE and Cochrane Library was performed to identify articles that assessed the association between miR-200 family expression and the survival of women with ovarian cancer. Summary hazard ratios and 95% confidence interval were calculated to estimate the effect. RESULTS:A total of seven articles, consisting of 553 women, were included in this meta-analysis. Overall, significantly improved overall survival/progression-free survival were observed with higher expression of the miR-200 family in women with ovarian cancer (overall survival, hazard ratio = 0.34, 95% confidence interval 0.20-0.58; progression-free survival, hazard ratio = 0.64, 95% confidence interval 0.50-0.82). Subgroup analysis revealed that there was a significant association between enhanced expression of the miR-200c and improved overall survival (hazard ratio = 0.20, 95% confidence interval 0.10-0.42) and progression-free survival (hazard ratio = 0.30, 95% confidence interval 0.11-0.81). Moreover, in the Asian population, a significant association was found between higher expression of the miR-200 family and improved overall survival (hazard ratio = 0.20, 95% confidence interval 0.09-0.45). CONCLUSION:High expression of miR-200c may predict improved survival in women with ovarian cancer and high expression of the miR-200 family significantly improves overall survival for Asian women.
journal_name
Acta Obstet Gynecol Scandjournal_title
Acta obstetricia et gynecologica Scandinavicaauthors
Shi C,Zhang Zdoi
10.1111/aogs.12883subject
Has Abstractpub_date
2016-05-01 00:00:00pages
505-12issue
5eissn
0001-6349issn
1600-0412journal_volume
95pub_type
杂志文章,meta分析,评审abstract:BACKGROUND:To describe the prevalence of women using systemic hormone replacement therapy in various age groups. To identify their reasons for choosing or not choosing the therapy, reasons for discontinuing the treatment, the prevalence of side effects among current users, and to estimate the duration of treatment. ME...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract::The objective of this study was to assess the cost-effectiveness of hysterectomy performed for benign indications. Hysterectomy remains the most common major gynecological operation in the Western world. Rates of hysterectomy have not declined as expected with the introduction of new treatment options. Furthermore, us...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/aogs.12299
更新日期:2014-03-01 00:00:00
abstract::A case of traumatic rupture of a normal spleen in a complicated delivery is presented. The etiology of splenic rupture and therapeutic aspects of this unusual occurrence are discussed. It is pointed out that a violent expression of the fetus might be dangerous for the mother. ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016347809155903
更新日期:1978-01-01 00:00:00
abstract::One hundred and ten singleton breech infants with a birth-weight less than 2 500 g have been delivered at Huddinge University Hospital during the years 1972-78. The cesarean section rate was 30.1 per cent. Vaginal and abdominal deliveries were compared with regard to perinatal mortality and asphyxial morbidity at birt...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348109154124
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:Patients after treatment for cervical cancer have increased risk of developing second squamous cell malignancy of the lower genital tract. MATERIAL AND METHODS:A retrospective study of 46 patients with second lower genital tract epidermoid cancers following previous treatment for invasive cervical carcinoma...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:The objective was to elicit whether hormonal responses to and subjective symptoms of hypoglycemia are modified during pregnancy in patients with insulin-dependent diabetes mellitus. METHODS:In ten type I diabetic women, hyperinsulinemic hypoglycemic clamps, with target arterial blood glucose content of 2.2 ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0412.1998.770609.x
更新日期:1998-07-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to describe the echographic features and perinatal outcomes of fetuses with absence of ductus venosus. MATERIAL AND METHODS:Retrospective review of 10 cases with absence of ductus venosus diagnosed by prenatal ultrasonography between January 2014 and February 2016 at a single...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.13176
更新日期:2017-10-01 00:00:00
abstract::In premenopausal women ovaries are the major sites of estrogen production, while in postmenopausal women estrogen is produced by aromatization of ovarian and adrenal androgens in extragonadal sites, mostly in adipose tissue. Aromatase is a cytochrome P450 hemoprotein-containing enzyme complex that catalyzes the rate-l...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.0001-6349.2004.00562.x
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVE:To investigate maternal risk factors and fetal conditions associated with abruption. METHODS:Prospective cohort study of 30,681 singleton pregnancies at least 28 weeks' gestation. Data collected by patient questionnaire at the first prenatal visit and by medical record review. RESULTS:307 women had abruptio...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349309021156
更新日期:1993-11-01 00:00:00
abstract:OBJECTIVE:To investigate the risk for anal sphincter tears (AST) in infibulated women. DESIGN:Population-based cohort study. SETTING:Nationwide study in Sweden. POPULATION:The study population included 250 491 primiparous women with a vaginal singleton birth at 37-41 completed gestational weeks during 1999-2008. We ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.12010
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Recent studies have indicated that the risk of thromboembolic disease (VTE) in users of combined oral contraceptive pills (COCs) varies not only with estrogen dose, but also with the progestogen in pills with the same estrogen dose. The aim of this article is to discuss sex hormone binding globulin (SHBG) as...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:
更新日期:2002-06-01 00:00:00
abstract:OBJECTIVE:To study the density of nerve fibers in cases of deep infiltrating endometriosis (DIE) of the rectovaginal septum in relation to various clinical factors. DESIGN:A research laboratory-based study. SETTING:A tertiary center together with a research laboratory. METHODS:Archived DIE tissue samples from 45 wom...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.12652
更新日期:2015-07-01 00:00:00
abstract::Serum folate levels were determined by a radio-isotopic assay method and then analysed in 253 normal full-term pregnant women. None of them had received any hematonic during their whole pregnancy period. Their mean age was 27.72 years and the mean pregnancy duration was 39.50 weeks. Mean hemoglobin concentration in th...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348809004252
更新日期:1988-01-01 00:00:00
abstract::Ovarian cancer often presents at an advanced stage, but tends to be an intra-peritoneal disease that respects peritoneal planes. Thus, colo-rectal perforation of the tumor is an extremely rare presentation. The surgical treatment of malignant colo-ovarian fistula should include complete cyto-reduction at the same time...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349.2010.501857
更新日期:2010-10-01 00:00:00
abstract::To investigate developments in perinatal care, all fetal and neonatal deaths among those born after at least 24 weeks of gestation at the University Hospital of Tromsø, Norway from 1976 to 1989, were subjected to medical audit. A decrease in total mortality rate was found when based on maturity (greater than or equal ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349109007872
更新日期:1991-01-01 00:00:00
abstract::Researchers in Copenhagen, Denmark conducted a study to determine if an IUD in a normal woman retards endometrial development. 14 Lippes loop users and 14 controls were studied. The device users had had their IUDs inserted at least 1 year previously and menstruated regularly. The basal temperature curve determined ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016347309158323
更新日期:1973-01-01 00:00:00
abstract::The results of 204 cases of regional analgesia by means of continuous epidural block during labour and delivery are reported. The frequency of instrummental intervention using forceps or the vacuum extractor is low, less than 15% for primi- and multi-gravidas combined, although pathological conditions were recognized ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016347509157101
更新日期:1975-01-01 00:00:00
abstract::In 1969 the Scan-Gallup institution interviewed a random sample of 503 women from all parts of Norway who had given birth during the last 24 months. Cesarean sections and forceps deliveries were excluded. The interviews revealed that 69% of the women were left unattended for a considerable part of the delivery, that t...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348909009899
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:To estimate the effect of vesicoamniotic shunting using a double-basket catheter on treating fetal bladder outlet obstruction. METHODS:A retrospective study involving 8 prenatally diagnosed bladder outlet obstruction cases that underwent vesicoamniotic shunt placement using a double-basket catheter from 199...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016340500449923
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:In this cross-sectional study, we analyze whether foreign-born women in Sweden had more non-normal childbirths than Swedish-born women during 1996-1998, adjusting for age, parity, level of education, number of antenatal care visits, and complications in pregnancy. METHODS:The study includes 215 497 singleto...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.0001-6349.2005.00686.x
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND:Anal sphincter tears during vaginal delivery are a major cause of anal incontinence. We wanted to assess the incidence in a Norwegian county where primary repairs are performed in four hospitals using similar per- and postoperative protocol for the treatment of such injuries. METHODS:A postal questionnaire ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.0001-6349.2004.00647.x
更新日期:2004-10-01 00:00:00
abstract:INTRODUCTION:The aim of this study is to evaluate the quality of the endometrial sample obtained by office endometrial aspiration when performed before or after saline contrast sonohysterography (SCSH) in women with postmenopausal bleeding and a thickened endometrium. To conduct a complete, minimally invasive and cost-...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.14086
更新日期:2021-01-17 00:00:00
abstract:BACKGROUND:Preterm infants are at 8 times higher risk than term infants for pre- and perinatal brain damage, resulting in cerebral palsy. In this paper we have analysed the influence of prenatal and birth-related risk factors on cerebral palsy in preterm infants. METHODS:In a register-based study, 175 preterm singleto...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,评审
doi:10.3109/00016349709024363
更新日期:1997-10-01 00:00:00
abstract::Minor degrees of endometriosis have often been regarded as being of no import and hence remain untreated, but a study of the natural history of endometriosis has demonstrated that 47% (95% confidence limits, 23-71%) of patients (n=35) given placebo in a double-blind, randomized controlled trial showed progression of t...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.1989.68.s150.27
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:To compare the diagnostic characteristics of the evaluation of myometrial invasion (MI) retrospectively between preoperative magnetic resonance imaging (MRI) and intraoperative frozen sections. DESIGN:A retrospective study. SETTING:University hospital. SAMPLE:201 women diagnosed with endometrial carcinoma....
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.12048
更新日期:2013-05-01 00:00:00
abstract:AIM OF STUDY:To clarify the impact of the presence of pelvic inflammatory disease (PID) and activation of the acute phase response on the serum level of tetranectin (Se-TN), a potential new tumor marker for ovarian cancer. MATERIALS AND METHODS:The study group consisted of 70 patients with a laparoscopically verified ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349509008939
更新日期:1995-03-01 00:00:00
abstract:BACKGROUND:In hypoxic conditions, fetal breathing movements (FBM) are reportedly inhibited with simultaneous elevation of the plasma level of catecholamines and arginine vasopressin (AVP). Although some kinds of catecholamines are reported to inhibit FBM, the effects of AVP on FBM are still unknown. The present study w...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349709050063
更新日期:1997-02-01 00:00:00
abstract:BACKGROUND:To evaluate vaginal stimulation of the pudendal nerve, a new method for investigation of pudendal nerve terminal motor latency (PNTML) and to assess the reproducibility of the method. METHODS:Thirteen healthy women and 11 female patients, median age 31 years (range 21-53 years), participated in the study. T...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0412.1997.tb07981.x
更新日期:1997-04-01 00:00:00
abstract:BACKGROUND:Clinical studies show that analysis of the fetal electrocardiographic (FECG) ST waveform at term gives important information on the myocardial response to intrapartum asphyxia. However, it is not known whether the preterm fetus responds in a similar fashion. The objective of the present study was to evaluate...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.0001-6349.2005.00594.x
更新日期:2005-02-01 00:00:00
abstract::The effect of physical exercise on beta-endorphin (beta-E) concentration in plasma was studied in 8 non-pregnant and in 8 pregnant women in their last trimester of pregnancy, using a 10-min bicycle ergometer test. In the non-pregnant women the mean beta-E levels were 2.4 +/- 0.7 (S.E.) pmol/l before the test, 4.3 +/- ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348609158397
更新日期:1986-01-01 00:00:00